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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Acinetobacter baumannii ATCC 17978  A1S_0687  ABO11131.2  429 aa histidinol dehydrogenase 0.00039 ●●○○○ -1.17 -1.16964462962683
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2393  AIK80990.1  207 aa hypothetical protein 0.00038 ●●○○○ -1.17 -1.16801668278664
Escherichia coli M12  CO715_20160  ATI07832.1  457 aa proline-specific permease ProY 1.7e-66 ●●○○○ -1.17 -1.16790987653641
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2937  AIK81523.1  107 aa copper binding protein CutA <1e-323 ●●○○○ -1.17 -1.16779396323001
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0214  NP_229871.2  Q9KVD2  slmA  196 aa nucleoid occlusion protein 2.7e-9 ●●○○○ -1.17 -1.167619893482
Escherichia coli M12  CO715_19030  ATI07624.1  222 aa DUF3313 domain-containing protein 2.2e-14 ●●○○○ -1.17 -1.16749258450791
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0372  WP_001651666.1  E8XJQ6  res  990 aa type III restriction-modification system endonuclease 2.5e-7 ●●○○○ -1.17 -1.16739937170446
Acinetobacter baumannii ATCC 17978  A1S_1531  ABO11958.1  232 aa putative cobalamin biosynthetic protein (CobB) 1.0e-11 ●●○○○ -1.17 -1.16739335511064
Escherichia coli M12  CO715_13205  ATI06580.1  312 aa malate dehydrogenase 1.9e-13 ●●○○○ -1.17 -1.16686664646516
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4792  WP_000371685.1  E8XDC0  rob  289 aa MDR efflux pump AcrAB transcriptional activator RobA 0.02 ●●○○○ -1.17 -1.16684993257363
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2590  AIK81187.1  338 aa lipoate-protein ligase A <1e-323 ●●○○○ -1.17 -1.16662138683095
Escherichia coli CFT073  c1857  AAN80320.1  A0A0H2V9I3  ydcO  431 aa Hypothetical protein ydcO 0.022 ●●○○○ -1.17 -1.16646771013607
Escherichia coli M12  CO715_03540  ATI04892.1  257 aa histidine transport ATP-binding protein HisP 1.8e-12 ●●○○○ -1.17 -1.16644935443667
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2571  AIK81168.1  309 aa homoserine kinase <1e-323 ●●○○○ -1.17 -1.16614188984443
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1757  NP_231393.1  Q9KR85  1016 aa AcrB/AcrD/AcrF family transporter 7.7e-8 ●●○○○ -1.17 -1.16612445305077
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3136  AIK81708.1  387 aa acetyl-CoA C-acyltransferase FadA 7.5e-13 ●●○○○ -1.16 -1.1646259334418
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3408  AIK81965.1  459 aa lamB porin family protein 4.6e-11 ●●○○○ -1.16 -1.1645554105222
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3380  WP_000422143.1  E8XBF4  yqjA  220 aa DedA family protein 7.7e-5 ●●○○○ -1.16 -1.16354529307151
Escherichia coli M12  CO715_10440  ATI06079.1  433 aa two-component system sensor histidine kinase RstB 3.3e-51 ●●○○○ -1.16 -1.16352831023718
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2257  AIK80862.1  52 aa hypothetical protein 3.3e-9 ●●○○○ -1.16 -1.16351415139484
Escherichia coli M12  CO715_12375  ATI06430.1  110 aa tRNA-binding protein 2.0e-29 ●●○○○ -1.16 -1.16227643415169
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0927  NP_233312.1  Q9KL22  116 aa hypothetical protein 0.0017 ●●○○○ -1.16 -1.16130458705038
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0008  NP_232409.1  Q9KNF6  553 aa methyl-accepting chemotaxis protein 9.8e-5 ●●○○○ -1.16 -1.16125034290452
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3579  AIK82134.1  158 aa cellulose synthase subunit D family protein <1e-323 ●●○○○ -1.16 -1.16116304375448
Escherichia coli M12  CO715_21385  ATI08054.1  190 aa elongation factor P-like protein YeiP 1.0e-60 ●●○○○ -1.16 -1.16081591205195
Escherichia coli M12  CO715_12150  ATI06394.1  187 aa type II secretion system protein GspH 0.00031 ●●○○○ -1.16 -1.1606072660377
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4432  AIK82975.1  113 aa nitrous oxide-stimulated promoter family protein 4.0e-7 ●●○○○ -1.16 -1.16002458144343
Escherichia coli M12  CO715_17440  ATI07345.1  147 aa cysteine desulfurase sulfur acceptor subunit CsdE 9.0e-14 ●●○○○ -1.16 -1.1597726819807
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2802  WP_001537507.1  E8XIF6  corE  263 aa inner membrane protein YpjD 7.6e-7 ●●○○○ -1.16 -1.15969180074488
Escherichia coli M12  CO715_14740  ATI06859.1  127 aa aspartate 1-decarboxylase autocleavage activator PanM 4.6e-5 ●●○○○ -1.16 -1.15935538995221
Escherichia coli M12  CO715_13885  ATI06701.1  321 aa EamA/RhaT family transporter 5.5e-13 ●●○○○ -1.16 -1.15872945190946
Escherichia coli M12  CO715_06435  ATI05384.1  1247 aa nitrate reductase subunit alpha 7.2e-76 ●●○○○ -1.16 -1.15810351386671
Escherichia coli M12  CO715_09925  ATI05999.1  318 aa Fe2+-enterobactin ABC transporter substrate-binding protein 2.7e-7 ●●○○○ -1.16 -1.15747757582397
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1488  NP_231129.1  Q9KRZ5  rlmL  708 aa 23S rRNA m(2)G2445 methyltransferase 9.9e-8 ●●○○○ -1.16 -1.15670497402129
Escherichia coli M12  CO715_10800  ATI06142.1  470 aa pyruvate kinase 0.00052 ●●○○○ -1.16 -1.15643434575272
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0029  CBW16130.1  A0A0H3NGZ4  109 aa hypothetical membrane protein 0.032 ●●○○○ -1.16 -1.15627988287064
Escherichia coli M12  CO715_04350  ATI05044.1  458 aa two-component system sensor histidine kinase ZraS 1.5e-47 ●●○○○ -1.16 -1.15601705372422
Escherichia coli M12  CO715_06710  ATI05433.1  513 aa Na+/H+ antiporter NhaB 4.7e-20 ●●○○○ -1.16 -1.15539111568148
Acinetobacter baumannii ATCC 17978  A1S_0144  ABO10627.2  259 aa high affinity Zn transport protein 2.7e-5 ●●○○○ -1.15 -1.15435925615193
Acinetobacter baumannii ATCC 17978  A1S_1530  ABO11957.2  480 aa SSS family major sodium/proline symporter 9.0e-12 ●●○○○ -1.15 -1.15424005824367
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0274  NP_232672.1  Q9KMP6  239 aa carbonic anhydrase 1.3e-7 ●●○○○ -1.15 -1.15409580957926
Porphyromonas gingivalis ATCC 33277  PGN_0714  WP_012457721.1  B2RIN8  170 aa isochorismatase family protein <1e-323 ●●○○○ -1.15 -1.15396514016751
Escherichia coli M12  CO715_18225  ATI07483.1  314 aa Band 7 protein 1.4e-6 ●●○○○ -1.15 -1.15372194756749
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3244  AIK81805.1  105 aa met Apo-repressor, MetJ family protein 8.3e-8 ●●○○○ -1.15 -1.15358582958416
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2753  AIK81343.1  199 aa hypothetical protein 3.8e-15 ●●○○○ -1.15 -1.15345247107761
Escherichia coli M12  CO715_15615  ATI07014.1  113 aa PTS fructose-like transporter subunit EIIB 1.3e-9 ●●○○○ -1.15 -1.15330465553899
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4028  AIK82575.1  275 aa calcineurin-like phosphoesterase family protein 0.00053 ●●○○○ -1.15 -1.1527808329847
Escherichia coli M12  CO715_05155  ATI05171.1  183 aa flagella biosynthesis regulatory protein FliZ 1.6e-14 ●●○○○ -1.15 -1.15267871749624
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2092  NP_231724.1  Q9KQA8  431 aa type II citrate synthase 6.8e-7 ●●○○○ -1.15 -1.15261081126282
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3929  WP_000015517.1  E8XGV3  rhuM  57 aa transposase 3.6e-7 ●●○○○ -1.15 -1.15188798414917
Escherichia coli M12  CO715_10365  ATI06065.1  111 aa acid shock protein 2.5e-14 ●●○○○ -1.15 -1.15184413343925
Escherichia coli M12  CO715_06520  ATI05400.1  277 aa protein-(glutamine-N5) methyltransferase, release factor-specific 0.029 ●●○○○ -1.15 -1.15184413343925
Escherichia coli M12  CO715_19655  ATI07739.1  168 aa ferritin-like domain-containing protein 1.8e-37 ●●○○○ -1.15 -1.151635487425
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4114  WP_000138962.1  E8XIP2  hemX  389 aa uroporphyrinogen-III C-methyltransferase 0.02 ●●○○○ -1.15 -1.15147618575031
Escherichia coli M12  CO715_23045  ATI08350.1  167 aa protein FimG 2.6e-27 ●●○○○ -1.15 -1.14996631931101
Escherichia coli M12  CO715_10830  ATI06148.1  248 aa Fe-S cluster assembly ATPase SufC 4.2e-13 ●●○○○ -1.15 -1.14996631931101
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1866  WP_000416128.1  E8X9A2  457 aa MFS transporter 0.036 ●●○○○ -1.15 -1.14951347366693
Escherichia coli M12  CO715_22745  ATI08296.1  357 aa patatin family protein 1.5e-41 ●●○○○ -1.15 -1.14913173525401
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0964  NP_230611.1  Q9KTD8  169 aa PTS system glucose-specific transporter subunit 4.8e-7 ●●○○○ -1.15 -1.14892915230687
Escherichia coli M12  CO715_19415  ATI07695.1  461 aa APC family permease 2.5e-20 ●●○○○ -1.15 -1.14892308923976
Escherichia coli M12  CO715_14845  ATI06878.1  231 aa pirin family protein 3.7e-28 ●●○○○ -1.15 -1.14808850518277
Escherichia coli M12  CO715_10380  ATI06068.1  109 aa spermidine export protein MdtI 1.8e-5 ●●○○○ -1.15 -1.14767121315427
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0901  NP_230548.1  Q9KTK1  753 aa hypothetical protein 1.0e-6 ●●○○○ -1.15 -1.14718278079684
Escherichia coli M12  CO715_17395  ATI07337.1  591 aa L-fucose isomerase 3.2e-6 ●●○○○ -1.15 -1.14683662909727
Porphyromonas gingivalis ATCC 33277  PGN_1373  WP_012458224.1  B2RKJ7  199 aa response regulator transcription factor 4.2e-5 ●●○○○ -1.15 -1.14683469931531
Escherichia coli M12  CO715_20385  ATI07874.1  179 aa DUF2058 domain-containing protein 4.0e-40 ●●○○○ -1.15 -1.14579339902603
Escherichia coli M12  CO715_01150  ATI08701.1  139 aa D-ribose pyranase 2.8e-28 ●●○○○ -1.15 -1.14537610699753
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3647  WP_000472323.1  E8XEI3  56 aa DUF4223 domain-containing protein 0.005 ●●○○○ -1.14 -1.14371027030099
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3671  WP_000980662.1  E8XEK7  776 aa RNA-binding transcriptional accessory protein 2.1e-5 ●●○○○ -1.14 -1.14218408119039
Escherichia coli M12  CO715_09455  ATI08772.1  97 aa LexA regulated protein 7.2e-15 ●●○○○ -1.14 -1.14099454069831
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0414  NP_232808.1  Q9KME6  141 aa hypothetical protein 1.7e-6 ●●○○○ -1.14 -1.1408771937187
Acinetobacter baumannii ATCC 17978  A1S_2388  ABO12807.2  315 aa putative ferric acinetobactin transport system permease protein 1.0e-5 ●●○○○ -1.14 -1.14076975417065
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3935  WP_000106461.1  E8XGV9  slsA  226 aa isochorismatase family protein 0.00035 ●●○○○ -1.14 -1.14049857618994
Escherichia coli M12  CO715_06600  ATI05413.1  472 aa dihydroxyacetone kinase subunit DhaM 8.4e-19 ●●○○○ -1.14 -1.13953401859856
Acinetobacter baumannii ATCC 17978  A1S_2439  ABO12857.1  A3M7G3  mnmA  265 aa tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 0.00091 ●●○○○ -1.14 -1.13941817525628
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3874  AIK82424.1  183 aa mlaD 2.0e-7 ●●○○○ -1.14 -1.13927415379628
Escherichia coli M12  CO715_03050  ATI04806.1  308 aa LysR family transcriptional regulator 2.2e-14 ●●○○○ -1.14 -1.13911672657007
Escherichia coli M12  CO715_00055  ATI04266.1  107 aa iron-sulfur cluster assembly accessory protein 0.0013 ●●○○○ -1.14 -1.13890808055582
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3303  AIK81864.1  207 aa DSBA-like thioredoxin domain protein 0.0038 ●●○○○ -1.14 -1.13887267800632
Escherichia coli M12  CO715_10295  ATI06055.1  186 aa spermidine acetyltransferase 2.2e-36 ●●○○○ -1.14 -1.13869943454157
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4213  WP_000027730.1  E8XK98  fdhE  309 aa formate dehydrogenase accessory protein FdhE 0.025 ●●○○○ -1.14 -1.13854391815859
Escherichia coli M12  CO715_20025  ATI07806.1  454 aa MFS transporter 1.3e-5 ●●○○○ -1.14 -1.13849078852732
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3836  WP_000761305.1  E8XFX8  malS  675 aa alpha-amylase 4.2e-6 ●●○○○ -1.14 -1.13847223974403
Escherichia coli M12  CO715_07555  ATI05583.1  418 aa leucine-rich repeat domain-containing protein 2.6e-73 ●●○○○ -1.14 -1.13807349649882
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0120  WP_001575587.1  E8XH25  leuL  28 aa leu operon leader peptide 0.027 ●●○○○ -1.14 -1.13684209265436
Escherichia coli M12  CO715_04635  ATI05085.1  156 aa very short patch repair endonuclease 0.0095 ●●○○○ -1.14 -1.13640432838483
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1048  NP_233430.1  Q9KKQ4  311 aa Gfo/Idh/MocA family oxidoreductase 3.7e-5 ●●○○○ -1.14 -1.13591847861704
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0813  NP_233199.1  Q9KLD3  501 aa aminopeptidase 9.6e-7 ●●○○○ -1.14 -1.13569827580608
Escherichia coli M12  CO715_10940  ATI06168.1  548 aa cyclohexanecarboxylate-CoA ligase 1.2e-145 ●●○○○ -1.14 -1.13536109831359
Escherichia coli M12  CO715_10260  ATI06048.1  431 aa site-specific integrase 3.8e-119 ●●○○○ -1.13 -1.13473516027084
Escherichia coli M12  CO715_19325  ATI07678.1  242 aa murein peptide amidase A 1.8e-25 ●●○○○ -1.13 -1.13473516027084
Escherichia coli M12  CO715_18100  ATI07460.1  331 aa methylmalonyl Co-A mutase-associated GTPase MeaB 0.0019 ●●○○○ -1.13 -1.13306599215685
Escherichia coli M12  CO715_18595  ATI07548.1  211 aa 3-hexulose-6-phosphate synthase 2.8e-16 ●●○○○ -1.13 -1.1328573461426
Porphyromonas gingivalis ATCC 33277  PGN_1042  WP_012457979.1  B2RJL6  387 aa cytochrome d ubiquinol oxidase subunit II <1e-323 ●●○○○ -1.13 -1.13241071598625
Escherichia coli M12  CO715_10725  ATI06130.1  382 aa cyclopropane-fatty-acyl-phospholipid synthase 1.2e-5 ●●○○○ -1.13 -1.13223140809985
Escherichia coli M12  CO715_05340  ATI05202.1  286 aa protein-glutamate O-methyltransferase CheR 0.00027 ●●○○○ -1.13 -1.1320227620856
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3648  WP_000165562.1  E8XEI4  trpS  334 aa tryptophan--tRNA ligase 0.0063 ●●○○○ -1.13 -1.13199654250789
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1085  NP_233466.1  Q9KKL8  556 aa hypothetical protein 1.0e-5 ●●○○○ -1.13 -1.13189597926572
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1602  AIK80222.1  317 aa potH 2.3e-6 ●●○○○ -1.13 -1.13176969185565
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2328  AIK80933.1  255 aa glutamine amidotransferase domain protein <1e-323 ●●○○○ -1.13 -1.13172320333761
Retrieved entries 3,701–3,800 out of 36,363 total in 454.2 ms (Link to these results)