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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3870  AIK82420.1  328 aa putative isomerase <1e-323 ●●○○○ -1.08 -1.07811478605848
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1714  AIK80334.1  414 aa cardiolipin synthase 2 6.2e-5 ●●○○○ -1.08 -1.07636313949342
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4413  AIK82956.1  330 aa RNA polymerase sigma factor RpoS 6.8e-14 ●●○○○ -1.08 -1.07631682381031
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2079  AIK80684.1  260 aa hypothetical protein <1e-323 ●●○○○ -1.07 -1.07152830465808
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4195  AIK82740.1  146 aa urease subunit beta <1e-323 ●●○○○ -1.07 -1.07096536851981
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1933  AIK80539.1  402 aa enterochelin esterase <1e-323 ●●○○○ -1.07 -1.06974960138807
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3262  AIK81823.1  281 aa bacterial regulatory helix-turn-helix, AraC family protein <1e-323 ●●○○○ -1.07 -1.06957410474837
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2754  AIK81344.1  105 aa smpA / OmlA family protein <1e-323 ●●○○○ -1.07 -1.06661919627562
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3573  AIK82128.1  59 aa hypothetical protein 1.8e-5 ●●○○○ -1.07 -1.0657358621992
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4201  AIK82746.1  388 aa emrA Membrane Fusion Protein <1e-323 ●●○○○ -1.06 -1.06477427169298
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4556  AIK83094.1  266 aa putative oxalate/formate antiporter 1.7e-15 ●●○○○ -1.06 -1.06241164508471
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2765  AIK81355.1  415 aa integrase <1e-323 ●●○○○ -1.06 -1.06063190807365
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1401  AIK80025.1  67 aa hypothetical protein 0.044 ●●○○○ -1.06 -1.05994770516475
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3918  AIK82465.1  147 aa putative uPF0306 protein yhbP 4.0e-6 ●●○○○ -1.06 -1.05610319639839
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3149  AIK81721.1  253 aa uridine phosphorylase <1e-323 ●●○○○ -1.05 -1.05211258488101
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1039  AIK79662.1  251 aa phenylacetic acid catabolic family protein 1.5e-7 ●●○○○ -1.05 -1.04862613375556
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4069  AIK82616.1  37 aa hypothetical protein <1e-323 ●●○○○ -1.05 -1.04604044610017
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3827  AIK82377.1  296 aa aaeAB Hydroxylated, Aromatic Carboxylic Acid Efflux Transport System Protein A <1e-323 ●●○○○ -1.04 -1.043898931173
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4606  AIK83140.1  159 aa positive regulator of sigma(E), RseC/MucC familyprotein 2.5e-13 ●●○○○ -1.04 -1.04304811521491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2205  AIK80810.1  320 aa pfkB carbohydrate kinase family protein 7.8e-16 ●●○○○ -1.04 -1.04212003942494
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1235  AIK79858.1  492 aa succinylglutamic semialdehyde dehydrogenase <1e-323 ●●○○○ -1.04 -1.04151594851957
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3465  AIK82021.1  142 aa hypothetical protein 7.0e-5 ●●○○○ -1.04 -1.03744036088528
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3054  AIK81639.1  136 aa phosphate-starvation-inducible E family protein <1e-323 ●●○○○ -1.03 -1.03081743746938
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1962  AIK80568.1  253 aa ABC transporter family protein <1e-323 ●●○○○ -1.03 -1.03054879846423
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5129  AIK83654.1  50 aa hypothetical protein 2.5e-5 ●●○○○ -1.03 -1.0279774849597
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4126  AIK82672.1  342 aa erythrose-4-phosphate dehydrogenase 9.6e-8 ●●○○○ -1.03 -1.02725963644926
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2070  AIK80675.1  355 aa phosphoribosylaminoimidazole carboxylase, ATPasesubunit 0.00055 ●●○○○ -1.02 -1.01848201851722
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3320  AIK81877.1  139 aa D-ribose utilization <1e-323 ●●○○○ -1.02 -1.01596717820902
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1614  AIK80234.1  183 aa putative bacterial nucleoid DNA-binding protein 0.021 ●●○○○ -1.02 -1.01589664069229
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4300  AIK82845.1  417 aa N-acetylmuramyl-L-alanine amidase 1.8e-9 ●●○○○ -1.01 -1.01411107411875
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3140  AIK81713.1  263 aa magnesium-dependent DNase 1.4e-5 ●●○○○ -1.01 -1.01040835373583
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4486  AIK83029.1  166 aa recX family protein 9.3e-6 ●●○○○ -1.01 -1.00915543094441
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2997  AIK81582.1  185 aa fimbrial family protein 8.9e-16 ●●○○○ -1.01 -1.0084704976927
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4707  AIK83241.1  117 aa transcriptional regulator, Spx/MgsR family protein <1e-323 ●●○○○ -1.01 -1.00721993698053
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3090  AIK81671.1  145 aa heavy-metal resistance family protein 6.8e-14 ●●○○○ -1 -1.00421132778764
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4248  AIK82793.1  190 aa bacterial regulatory, luxR family protein 1.0e-7 ●○○○○ -1 -0.998760026482244
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4033  AIK82580.1  449 aa sensor protein qseC <1e-323 ●○○○○ -1 -0.998650617643058
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3875  AIK82425.1  211 aa mlaC <1e-323 ●○○○○ -1 -0.995565599647985
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3562  AIK82118.1  187 aa 3-methyladenine DNA glycosylase I <1e-323 ●○○○○ -0.99 -0.994515768097818
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3480  AIK82036.1  566 aa acyltransferase family protein <1e-323 ●○○○○ -0.99 -0.986858504858952
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3183  AIK81751.1  416 aa polysaccharide biosynthesis family protein 1.6e-8 ●○○○○ -0.98 -0.984524320293708
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2522  AIK81119.1  275 aa dnaJ domain protein <1e-323 ●○○○○ -0.98 -0.981282605576323
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4277  AIK82823.1  338 aa galR transcriptional repressor GalR transcriptional dual regulator 8.0e-14 ●○○○○ -0.98 -0.979822889893516
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2356  AIK80953.1  118 aa putative regulator in colanic acid synthesis; interacts with RcsB <1e-323 ●○○○○ -0.98 -0.979493696628959
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4353  AIK82896.1  131 aa hypothetical protein <1e-323 ●○○○○ -0.98 -0.97813487626046
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3285  AIK81846.1  309 aa formate dehydrogenase accessory protein FdhE <1e-323 ●○○○○ -0.97 -0.972443856350512
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2510  AIK81107.1  281 aa araC 0.0026 ●○○○○ -0.97 -0.969086751204925
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2384  AIK80981.1  264 aa methionine aminopeptidase, type I 0.00056 ●○○○○ -0.97 -0.967101492042232
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1212  AIK79835.1  179 aa intracellular septation protein A 4.2e-5 ●○○○○ -0.96 -0.963354555175817
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3897  AIK82446.1  209 aa cyclic nucleotide-binding domain protein <1e-323 ●○○○○ -0.96 -0.962857601616783
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3193  AIK81761.1  109 aa thioredoxin <1e-323 ●○○○○ -0.96 -0.961449885955664
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2983  AIK81568.1  252 aa hypothetical protein 1.0e-12 ●○○○○ -0.95 -0.954975034736963
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2593  AIK81190.1  440 aa thymidine phosphorylase <1e-323 ●○○○○ -0.95 -0.951697280153892
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3658  AIK82213.1  295 aa ugpA <1e-323 ●○○○○ -0.95 -0.947259212829144
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2740  AIK81330.1  865 aa pglZ domain protein 2.2e-5 ●○○○○ -0.95 -0.94582770858952
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4080  AIK82626.1  360 aa hypothetical protein <1e-323 ●○○○○ -0.95 -0.945779845767583
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3532  AIK82088.1  161 aa putative electron transport protein HydN 4.2e-8 ●○○○○ -0.95 -0.945278893391205
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3314  AIK81872.1  327 aa rbsR transcriptional repressor <1e-323 ●○○○○ -0.94 -0.943373438349715
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3296  AIK81857.1  349 aa ntrB 0.0059 ●○○○○ -0.94 -0.942097770193866
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1951  AIK80557.1  195 aa transcriptional repressor BetI 1.2e-6 ●○○○○ -0.94 -0.941839188820062
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3057  AIK81642.1  106 aa branched-chain amino acid transport family protein 0.0041 ●○○○○ -0.93 -0.934510037903876
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2275  AIK80880.1  221 aa HAD phosphoserine phosphatase-like hydrolase, IBfamily protein 2.0e-6 ●○○○○ -0.93 -0.931101635176441
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3139  AIK81711.1  39 aa hypothetical protein 7.3e-14 ●○○○○ -0.93 -0.931071153921515
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3258  AIK81819.1  457 aa sensory histidine kinase in two-component regulatory system with CpxR 8.6e-10 ●○○○○ -0.93 -0.927785839947628
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4213  AIK82758.1  190 aa hypothetical protein 5.0e-15 ●○○○○ -0.93 -0.926783136840346
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3553  AIK82109.1  218 aa hypothetical protein <1e-323 ●○○○○ -0.92 -0.922987540040914
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3734  AIK82289.1  72 aa hypothetical protein <1e-323 ●○○○○ -0.92 -0.920457861466697
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4723  AIK83257.1  279 aa ethanolamine utilization protein EutJ 1.2e-11 ●○○○○ -0.91 -0.912491624034988
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3735  AIK82290.1  319 aa alpha/beta hydrolase fold family protein <1e-323 ●○○○○ -0.91 -0.912104017155658
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1727  AIK80347.1  70 aa putative dTDP-4-dehydrorhamnose reductase 0.019 ●○○○○ -0.91 -0.907755497736225
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4275  AIK82820.1  470 aa 6-phospho-beta-glucosidase gmuD <1e-323 ●○○○○ -0.91 -0.905015974041412
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4421  AIK82964.1  50 aa hokE 2.3e-7 ●○○○○ -0.9 -0.904019256961218
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4088  AIK82634.1  342 aa periplasmic binding and sugar binding domain of LacI family protein 0.00022 ●○○○○ -0.9 -0.901448683076368
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3369  AIK81926.1  367 aa galactonate dehydratase 9.2e-14 ●○○○○ -0.9 -0.899250114078673
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3078  AIK81663.1  434 aa isocitrate lyase 1.8e-15 ●○○○○ -0.9 -0.898960138362041
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2806  AIK81395.1  150 aa toxin-antitoxin biofilm protein 5.6e-7 ●○○○○ -0.9 -0.898624269355331
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2706  AIK81296.1  114 aa periplasmic copper/silver-binding protein <1e-323 ●○○○○ -0.89 -0.891693065265998
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4144  AIK82690.1  957 aa glycine dehydrogenase <1e-323 ●○○○○ -0.89 -0.890594645182373
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1985  AIK80591.1  194 aa bacterial regulatory, tetR family protein 7.0e-6 ●○○○○ -0.89 -0.88937556177052
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2870  AIK81459.1  91 aa hypothetical protein 2.6e-10 ●○○○○ -0.89 -0.887292615119137
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1195  AIK79818.1  452 aa indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase <1e-323 ●○○○○ -0.89 -0.886919473802629
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4282  AIK82827.1  72 aa putative lipoprotein 3.5e-9 ●○○○○ -0.88 -0.884552568868707
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2516  AIK81113.1  968 aa DEAD/DEAH box helicase family protein 1.1e-13 ●○○○○ -0.88 -0.88358554106087
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2860  AIK81449.1  274 aa bacterial regulatory helix-turn-helix, AraC family protein <1e-323 ●○○○○ -0.88 -0.877061037135237
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4071  AIK82618.1  103 aa gram-negative pili assembly chaperone, C-terminal domain protein 0.00082 ●○○○○ -0.88 -0.875765491085267
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2388  AIK80985.1  385 aa cdaR transcriptional activator 4.2e-11 ●○○○○ -0.88 -0.875381822778105
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4085  AIK82631.1  239 aa hypothetical protein <1e-323 ●○○○○ -0.87 -0.872420687470254
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3823  AIK82373.1  1236 aa hypothetical protein <1e-323 ●○○○○ -0.87 -0.87223904241984
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1616  AIK80236.1  49 aa hypothetical protein 0.0014 ●○○○○ -0.87 -0.872081416600331
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3727  AIK82282.1  200 aa stationary-phase protein with possible role in p-aminobenzoate/folate biosynthesis <1e-323 ●○○○○ -0.87 -0.871805035267212
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3364  AIK81921.1  354 aa hypothetical protein <1e-323 ●○○○○ -0.87 -0.869923413407085
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2389  AIK80986.1  433 aa degP 6.7e-16 ●○○○○ -0.87 -0.867903904276841
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3488  AIK82044.1  198 aa cell division inhibitor <1e-323 ●○○○○ -0.87 -0.86697816947006
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2654  AIK81248.1  126 aa 5-carboxymethyl-2-hydroxymuconate Delta-isomerase 8.4e-9 ●○○○○ -0.86 -0.862842860747616
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3009  AIK81594.1  78 aa hypothetical protein <1e-323 ●○○○○ -0.86 -0.86264995648728
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4066  AIK82613.1  456 aa CBS domain protein 4.8e-13 ●○○○○ -0.86 -0.861155492023929
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2768  AIK81357.1  489 aa sulfate transporter family protein 2.6e-15 ●○○○○ -0.86 -0.860589611123095
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2000  AIK80606.1  340 aa xylose isomerase-like TIM barrel family protein 2.6e-6 ●○○○○ -0.86 -0.859915664410589
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2127  AIK80732.1  513 aa EAL domain protein <1e-323 ●○○○○ -0.86 -0.859095917950609
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4119  AIK82665.1  264 aa putative short-chain dehydrogenase 0.00017 ●○○○○ -0.86 -0.856576530273263
Retrieved entries 301–400 out of 3,098 total in 23.1 ms (Link to these results)