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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1767  NP_231402.1  Q9KR76  470 aa hypothetical protein 3.3e-11 ●○○○○ -0.82 -0.821775936751
Acinetobacter baumannii ATCC 17978  A1S_0915  ABO11347.2  461 aa putative MFS transporter 3.2e-7 ●○○○○ -0.82 -0.821702989031606
Escherichia coli M12  CO715_14200  ATI06756.1  265 aa iron(3+)-hydroxamate import ATP-binding protein FhuC 0.00023 ●○○○○ -0.82 -0.821557492883299
Porphyromonas gingivalis ATCC 33277  PGN_1049  WP_012457985.1  B2RJM3  563 aa alkaline phosphatase <1e-323 ●○○○○ -0.82 -0.821479545028774
Escherichia coli M12  CO715_07725  ATI05612.1  69 aa hypothetical protein 0.0011 ●○○○○ -0.82 -0.821348846869051
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1915  WP_000173431.1  E8X9F0  purT  392 aa formate-dependent phosphoribosylglycinamide formyltransferase 0.00015 ●○○○○ -0.82 -0.820559896835869
Escherichia coli M12  CO715_06200  ATI05346.1  339 aa aldo/keto reductase 0.00072 ●○○○○ -0.82 -0.820514262812055
Escherichia coli M12  CO715_11455  ATI06267.1  212 aa leucine efflux protein 3.4e-19 ●○○○○ -0.82 -0.820305616797806
Porphyromonas gingivalis ATCC 33277  PGN_0703  WP_012457712.1  B2RIM7  308 aa hypothetical protein <1e-323 ●○○○○ -0.82 -0.820274276056904
Escherichia coli M12  CO715_21590  ATI08091.1  478 aa multidrug transporter permease 1.7e-24 ●○○○○ -0.82 -0.819262386726562
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3190  WP_000745625.1  E8X9L4  dsbC  237 aa bifunctional protein-disulfide isomerase/oxidoreductase DsbC 0.00015 ●○○○○ -0.82 -0.819053690436479
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0909  NP_230556.1  Q9KTJ3  316 aa trehalose repressor 4.8e-8 ●○○○○ -0.82 -0.818959679072182
Escherichia coli M12  CO715_12290  ATI08796.1  278 aa L(+)-tartrate dehydratase subunit alpha 8.4e-9 ●○○○○ -0.82 -0.818636448683815
Acinetobacter baumannii ATCC 17978  A1S_0712  ABO11156.2  406 aa hypothetical protein 2.3e-7 ●○○○○ -0.82 -0.818446542395372
Escherichia coli M12  CO715_07770  ATI05618.1  300 aa Fe(3+)-dicitrate ABC transporter substrate-binding protein FecB 2.0e-7 ●○○○○ -0.82 -0.818427802669566
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4750  WP_010989102.1  E8XCJ2  303 aa threonine/serine exporter ThrE family protein 0.0029 ●○○○○ -0.82 -0.817964521282867
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1153  WP_001159786.1  E8XES6  yceJ  190 aa cytochrome b 0.046 ●○○○○ -0.82 -0.817882770759265
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2664  WP_001100652.1  E8XGQ1  cadA  714 aa lysine decarboxylase CadA 0.0006 ●○○○○ -0.82 -0.817369780770856
Escherichia coli M12  CO715_08060  ATI05669.1  400 aa nicotinate phosphoribosyltransferase 0.011 ●○○○○ -0.82 -0.815298112455834
Porphyromonas gingivalis ATCC 33277  PGN_0388  WP_018964814.1  B2RHR2  tpx  167 aa thiol peroxidase <1e-323 ●○○○○ -0.82 -0.815192746283032
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4709  AIK83243.1  660 aa glutamate synthase, small subunit domain protein <1e-323 ●○○○○ -0.82 -0.815005777344398
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3510  WP_023893148.1  E8XD53  232 aa hypothetical protein 0.00047 ●○○○○ -0.81 -0.81466122784451
Escherichia coli M12  CO715_10315  ATI08784.1  807 aa dimethyl sulfoxide reductase subunit A 6.2e-23 ●○○○○ -0.81 -0.81404623637034
Escherichia coli M12  CO715_03110  ATI04812.1  400 aa nucleoside permease NupC 2.9e-10 ●○○○○ -0.81 -0.813420298327594
Escherichia coli M12  CO715_11885  ATI06345.1  219 aa DedA family protein 1.6e-5 ●○○○○ -0.81 -0.813420298327594
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3695  WP_010989078.1  E8XEN1  519 aa PstS family phosphate ABC transporter substrate-binding protein 0.0023 ●○○○○ -0.81 -0.813122518055959
Acinetobacter baumannii ATCC 17978  A1S_1590  ABO12017.2  220 aa peptidase U35 phage prohead HK97 0.0059 ●○○○○ -0.81 -0.813111114849171
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3359  WP_001281933.1  E8XBD4  uppP  273 aa undecaprenyl-diphosphate phosphatase 0.00037 ●○○○○ -0.81 -0.812519967569837
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2281  AIK80886.1  417 aa proA 1.0e-8 ●○○○○ -0.81 -0.812111736320002
Escherichia coli M12  CO715_13980  ATI06717.1  140 aa aminoacyl-tRNA hydrolase 0.034 ●○○○○ -0.81 -0.811959776227852
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2344  AIK80947.1  301 aa putative DNA-binding transcriptional regulator LYSR-type 0.00011 ●○○○○ -0.81 -0.811647674564552
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0894  NP_230541.2  Q9KTK8  thiI  483 aa thiamine biosynthesis protein ThiI 1.7e-6 ●○○○○ -0.81 -0.810359481181349
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4561  AIK83099.1  46 aa hypothetical protein 3.3e-6 ●○○○○ -0.81 -0.809558045017048
Porphyromonas gingivalis ATCC 33277  PGN_1535  WP_012458353.1  B2RL09  350 aa hypothetical protein 7.3e-11 ●○○○○ -0.81 -0.809492091398614
Acinetobacter baumannii ATCC 17978  A1S_0588  ABO11039.2  A3M295  283 aa hypothetical protein 4.4e-5 ●○○○○ -0.81 -0.809004645666305
Escherichia coli M12  CO715_11360  ATI06249.1  284 aa aldo/keto reductase 0.00035 ●○○○○ -0.81 -0.80862143999987
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4410  AIK82953.1  253 aa 5'/3'-nucleotidase SurE 9.4e-6 ●○○○○ -0.81 -0.807758251364924
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2619  NP_232247.1  Q9KNW1  193 aa para-aminobenzoate synthase component II 1.1e-7 ●○○○○ -0.81 -0.807725837676454
Escherichia coli CFT073  c2208  AAN80667.1  A0A0H2V985  rnd  375 aa Ribonuclease D 0.019 ●○○○○ -0.81 -0.807510359075225
Porphyromonas gingivalis ATCC 33277  PGN_1466  WP_012458292.1  B2RKU0  rgpB  736 aa Arg-gingipain RgpB <1e-323 ●○○○○ -0.81 -0.807351844438516
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0048  NP_232449.1  Q9KNB7  129 aa hypothetical protein 0.0026 ●○○○○ -0.81 -0.807218043685333
Escherichia coli M12  CO715_10695  ATI06124.1  389 aa MFS transporter 2.2e-5 ●○○○○ -0.81 -0.806952271885879
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1587  WP_000489731.1  E8XJ22  smvA  495 aa methyl viologen efflux MFS transporter SmvA 0.0032 ●○○○○ -0.81 -0.806041256231055
Escherichia coli M12  CO715_22770  ATI08301.1  148 aa ribosomal-protein-alanine N-acetyltransferase RimI 0.0024 ●○○○○ -0.81 -0.805909041814635
Escherichia coli M12  CO715_01020  ATI04437.1  296 aa phosphate ABC transporter, permease protein PstA 1.5e-7 ●○○○○ -0.8 -0.804657165729142
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0108  NP_229767.1  Q9KVN3  polA  934 aa DNA polymerase I 0.00018 ●○○○○ -0.8 -0.804448390836007
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3197  WP_001182976.1  E8X9M1  yqfB  103 aa ASCH domain-containing protein 0.043 ●○○○○ -0.8 -0.804372135090781
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5004  AIK83530.1  233 aa transcriptional regulatory, C terminal family protein 0.021 ●○○○○ -0.8 -0.804286418281508
Escherichia coli M12  CO715_12110  ATI06387.1  37 aa prepilin peptidase A domain protein 1.3e-5 ●○○○○ -0.8 -0.803822581672146
Escherichia coli M12  CO715_17850  ATI07415.1  310 aa carbamate kinase-like protein YqeA 7.0e-15 ●○○○○ -0.8 -0.803613935657897
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0924  NP_233309.2  Q9KL25  605 aa hypothetical protein 0.0052 ●○○○○ -0.8 -0.803524109089028
Escherichia coli M12  CO715_06860  ATI05459.1  403 aa diguanylate phosphodiesterase 9.0e-99 ●○○○○ -0.8 -0.803196643629399
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0105  NP_229764.1  Q9KVN6  347 aa delta-aminolevulinic acid dehydratase 2.2e-7 ●○○○○ -0.8 -0.802939352450293
Porphyromonas gingivalis ATCC 33277  PGN_1722  WP_005873721.1  B2RLJ6  udk  207 aa uridine kinase <1e-323 ●○○○○ -0.8 -0.802664364718876
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2101  AIK80706.1  57 aa hypothetical protein 3.2e-11 ●○○○○ -0.8 -0.802542888244859
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1503  WP_001211193.1  E8XI73  300 aa osmoprotectant ABC transporter substrate-binding protein OsmX 0.00016 ●○○○○ -0.8 -0.801770013639535
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0959  NP_230606.1  Q9KTE3  corC  291 aa hemolysin 0.00012 ●○○○○ -0.8 -0.801681695341681
Acinetobacter baumannii ATCC 17978  A1S_2379  ABO12798.2  A3M7A4  hdc  383 aa putative acinetobactin biosynthesis protein 7.1e-5 ●○○○○ -0.8 -0.801679472565328
Escherichia coli M12  CO715_17475  ATI07350.1  608 aa exodeoxyribonuclease V subunit alpha 4.1e-20 ●○○○○ -0.8 -0.80131882950116
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0520  NP_232911.1  Q9KM68  sbcD  379 aa exonuclease SbcD 0.0026 ●○○○○ -0.8 -0.801275889505114
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2454  AIK81051.1  37 aa hypothetical protein 5.2e-9 ●○○○○ -0.8 -0.801170075323225
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5101  AIK83627.1  409 aa esterase family protein 1.7e-11 ●○○○○ -0.8 -0.801112551160483
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4059  AIK82606.1  358 aa hypothetical protein 2.5e-11 ●○○○○ -0.8 -0.801090681601361
Escherichia coli M12  CO715_02655  ATI04732.1  487 aa beta-barrel assembly-enhancing protease 0.00017 ●○○○○ -0.8 -0.800901537472662
Acinetobacter baumannii ATCC 17978  A1S_1673  ABO12100.2  372 aa inner membrane permease protein 8.8e-7 ●○○○○ -0.8 -0.800854042317935
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3437  WP_000224386.1  E8XC96  mtr  414 aa tryptophan permease 0.0093 ●○○○○ -0.8 -0.800332013516472
Porphyromonas gingivalis ATCC 33277  PGN_0412  WP_012457491.1  B2RHT6  261 aa nucleoside triphosphate pyrophosphohydrolase 1.1e-8 ●○○○○ -0.8 -0.800209897371003
Escherichia coli M12  CO715_00375  ATI04325.1  400 aa 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD+ reductase component 2.1e-10 ●○○○○ -0.8 -0.799858307401418
Acinetobacter baumannii ATCC 17978  A1S_2922  ABO13327.1  100 aa hypothetical protein 0.00035 ●○○○○ -0.8 -0.799604715859376
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0740  NP_233127.1  Q9KLK3  216 aa hypothetical protein 0.0062 ●○○○○ -0.8 -0.799591719396575
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2649  AIK81243.1  146 aa homoprotocatechuate degradation operon regulator, HpaR <1e-323 ●○○○○ -0.8 -0.798529325637838
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2433  NP_232063.1  Q9KPD7  cpdA  272 aa cyclic 3',5'-adenosine monophosphate phosphodiesterase 0.0013 ●○○○○ -0.8 -0.798313674583863
Acinetobacter baumannii ATCC 17978  A1S_0348  ABO10808.2  539 aa 2-octaprenylphenol hydroxylase of ubiquinone biosynthetic pathway 4.7e-7 ●○○○○ -0.8 -0.798070393818427
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4955  AIK83481.1  305 aa substrate binding domain of ABC-type glycine betaine transport system family protein <1e-323 ●○○○○ -0.8 -0.798056558561303
Escherichia coli M12  CO715_18970  ATI07613.1  474 aa gamma-aminobutyraldehyde dehydrogenase 2.1e-20 ●○○○○ -0.8 -0.796937263201934
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0084  NP_232485.1  Q9KN81  148 aa DNA-binding transcriptional dual regulator SoxR 1.8e-5 ●○○○○ -0.8 -0.796195112437127
Escherichia coli M12  CO715_07670  ATI05605.1  460 aa diguanylate cyclase 1.8e-35 ●○○○○ -0.8 -0.795894033130689
Escherichia coli M12  CO715_21815  ATI08134.1  420 aa tagatose-bisphosphate aldolase subunit GatZ 4.9e-22 ●○○○○ -0.8 -0.795059449073694
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3503  WP_001739021.1  E8XD46  250 aa DUF695 domain-containing protein 0.00022 ●○○○○ -0.79 -0.794584014344156
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0463  WP_001239449.1  E8XKN0  cyoA  318 aa cytochrome o ubiquinol oxidase subunit II 0.00079 ●○○○○ -0.79 -0.793935211611597
Escherichia coli M12  CO715_14565  ATI06826.1  409 aa beta-ketoacyl-ACP synthase II 3.8e-30 ●○○○○ -0.79 -0.793807572988201
Escherichia coli M12  CO715_10910  ATI06162.1  303 aa AraC family transcriptional regulator 7.4e-36 ●○○○○ -0.79 -0.793598926973952
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1923  AIK80529.1  283 aa isochorismatase 1.4e-10 ●○○○○ -0.79 -0.793318070922716
Escherichia coli M12  CO715_02980  ATI04792.1  291 aa sulfate ABC transporter permease subunit CysW 0.0073 ●○○○○ -0.79 -0.792972988931205
Escherichia coli M12  CO715_08845  ATI05811.1  332 aa transporter 1.2e-7 ●○○○○ -0.79 -0.792764342916956
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3381  AIK81938.1  115 aa hypothetical protein 4.0e-12 ●○○○○ -0.79 -0.79242624750557
Escherichia coli M12  CO715_08375  ATI05726.1  550 aa hydroxylamine reductase 2.1e-5 ●○○○○ -0.79 -0.792347050888459
Escherichia coli M12  CO715_22035  ATI08175.1  464 aa undecaprenyl-phosphate glucose phosphotransferase 1.5e-12 ●○○○○ -0.79 -0.79213840487421
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3292  AIK81853.1  199 aa &alpha-D-glucose-1-phosphatase <1e-323 ●○○○○ -0.79 -0.791849074639035
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0515  WP_000670396.1  E8X881  ushA  550 aa bifunctional UDP-sugar hydrolase/5'-nucleotidase 0.00028 ●○○○○ -0.79 -0.791467654471908
Escherichia coli M12  CO715_08590  ATI05766.1  371 aa aldose dehydrogenase 2.8e-67 ●○○○○ -0.79 -0.790886528788717
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3802  WP_000028047.1  E8XFU7  dppA  535 aa ABC transporter substrate-binding protein 0.0065 ●○○○○ -0.79 -0.790862158432681
Acinetobacter baumannii ATCC 17978  A1S_2048  ABO12475.1  114 aa hypothetical protein 3.7e-6 ●○○○○ -0.79 -0.790709632575294
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1016  WP_000798705.1  E8XDH9  149 aa hypothetical protein 0.00065 ●○○○○ -0.79 -0.790547971986991
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3416  AIK81973.1  246 aa glcNAc-PI de-N-acetylase family protein <1e-323 ●○○○○ -0.79 -0.790443706000435
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4216  AIK82761.1  430 aa arsB <1e-323 ●○○○○ -0.79 -0.789582495421628
Escherichia coli M12  CO715_10790  ATI06140.1  208 aa hypothetical protein 5.8e-44 ●○○○○ -0.79 -0.789426006688975
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2982  AIK81567.1  305 aa hypothetical protein <1e-323 ●○○○○ -0.79 -0.789342512293834
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3264  AIK81825.1  488 aa rhamnulokinase <1e-323 ●○○○○ -0.79 -0.788709195666586
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3241  AIK81803.1  810 aa metL <1e-323 ●○○○○ -0.79 -0.788261631811689
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