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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3365  AIK81922.1  377 aa surface antigen family protein <1e-323 ●○○○○ -0.71 -0.706585300608322
Escherichia coli M12  CO715_02160  ATI04640.1  90 aa hypothetical protein 7.1e-12 ●○○○○ -0.7 -0.703463848818444
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4499  WP_000611307.1  E8X9V4  dcuR  239 aa two-component system response regulator DcuR 0.0051 ●○○○○ -0.7 -0.703104917737184
Porphyromonas gingivalis ATCC 33277  PGN_0463  WP_012457525.1  B2RHY7  593 aa hypothetical protein <1e-323 ●○○○○ -0.7 -0.703018122609377
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3675  AIK82230.1  431 aa glucose-1-phosphate adenylyltransferase <1e-323 ●○○○○ -0.7 -0.700627676114841
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1437  NP_231080.1  Q9KS24  790 aa cation transporter E1-E2 family ATPase 4.5e-6 ●○○○○ -0.7 -0.700415966292133
Porphyromonas gingivalis ATCC 33277  PGN_0532  WP_012457581.1  B2RI56  331 aa MoxR family ATPase 3.9e-14 ●○○○○ -0.7 -0.700396581543201
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4290  WP_000007508.1  E8XL62  metF  296 aa methylenetetrahydrofolate reductase 0.00094 ●○○○○ -0.7 -0.700228905027504
Escherichia coli M12  CO715_19390  ATI07691.1  426 aa FAD-binding oxidoreductase 0.0053 ●○○○○ -0.7 -0.700125512590462
Porphyromonas gingivalis ATCC 33277  PGN_0244  WP_012457361.1  B2RHB8  69 aa hypothetical protein 1.2e-13 ●○○○○ -0.7 -0.699943301149482
Porphyromonas gingivalis ATCC 33277  PGN_1210  WP_039417152.1  B2RK34  356 aa hypothetical protein 1.1e-9 ●○○○○ -0.7 -0.699943301149482
Porphyromonas gingivalis ATCC 33277  PGN_0530  WP_012457579.1  B2RI54  318 aa hypothetical protein 2.2e-7 ●○○○○ -0.7 -0.699943301149482
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2416  AIK81013.1  387 aa type II secretion system protein L 0.0084 ●○○○○ -0.7 -0.699078881271273
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0634  WP_000278499.1  E8X985  ybdQ  142 aa universal stress protein UspG 0.022 ●○○○○ -0.7 -0.698579482013967
Porphyromonas gingivalis ATCC 33277  PGN_0140  WP_012457275.1  B2RH14  msrA  352 aa peptide-methionine (R)-S-oxide reductase MsrB <1e-323 ●○○○○ -0.7 -0.698360684009222
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4245  AIK82790.1  279 aa fimbrial family protein 2.2e-16 ●○○○○ -0.7 -0.698295945401244
Escherichia coli M12  CO715_15955  ATI07073.1  729 aa fatty acid oxidation complex subunit alpha FadB <1e-323 ●○○○○ -0.7 -0.697830406433725
Escherichia coli M12  CO715_21985  ATI08165.1  405 aa colanic acid biosynthesis glycosyltransferase WcaC 1.3e-14 ●○○○○ -0.7 -0.697830406433725
Acinetobacter baumannii ATCC 17978  A1S_0790  ABO11230.2  269 aa putative membrane protein 0.021 ●○○○○ -0.7 -0.697592485233373
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2569  AIK81166.1  125 aa hypothetical protein 2.4e-7 ●○○○○ -0.7 -0.697394188039189
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4211  AIK82756.1  102 aa hypothetical protein <1e-323 ●○○○○ -0.7 -0.697197907420795
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3198  WP_001230141.1  E8X9M2  bglA  477 aa 6-phospho-beta-glucosidase 0.00049 ●○○○○ -0.7 -0.696918300676485
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3006  AIK81592.1  518 aa EAL domain protein <1e-323 ●○○○○ -0.7 -0.696739233290868
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2855  WP_000104129.1  E8XJ80  285 aa DNA adenine methylase 0.0009 ●○○○○ -0.7 -0.696597725101765
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5046  AIK83572.1  274 aa putative epimerase, with NAD(P)-binding Rossmann-fold domain 0.00035 ●○○○○ -0.7 -0.696182364699856
Escherichia coli M12  CO715_02025  ATI04616.1  171 aa transcriptional regulator Zur 2.6e-13 ●○○○○ -0.7 -0.695743946291236
Escherichia coli M12  CO715_24595  ATI08608.1  318 aa hypothetical protein 7.3e-70 ●○○○○ -0.7 -0.695326654262738
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2384  WP_001112763.1  E8XED0  58 aa hypothetical protein 0.0015 ●○○○○ -0.7 -0.695263418626585
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4278  AIK82822.1  159 aa acetyltransferase family protein 2.2e-8 ●○○○○ -0.7 -0.695181894687063
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2043  NP_231677.1  Q9KQF5  topB  647 aa DNA topoisomerase III 0.0035 ●○○○○ -0.7 -0.695159738305693
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1854  WP_001518647.1  E8X8K3  manZ  283 aa PTS mannose transporter subunit IID 0.0052 ●○○○○ -0.69 -0.694994095260451
Acinetobacter baumannii ATCC 17978  A1S_1825  ABO12252.2  182 aa hypothetical protein 8.0e-6 ●○○○○ -0.69 -0.694231056005562
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2658  NP_232286.1  Q9KNS3  frdC  127 aa fumarate reductase subunit C 2.0e-6 ●○○○○ -0.69 -0.692605655840492
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2121  NP_231752.1  Q9KQ80  260 aa flagellar biosynthesis protein FliR 3.7e-7 ●○○○○ -0.69 -0.692577802148635
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0705  NP_233092.1  Q9KLN8  789 aa phosphoglycerate transport regulatory protein PgtB 0.017 ●○○○○ -0.69 -0.692498603612666
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4848  AIK83375.1  509 aa NADH:ubiquinone oxidoreductase, membrane subunitM 0.00033 ●○○○○ -0.69 -0.692205452452173
Escherichia coli M12  CO715_19315  ATI07676.1  306 aa alpha/beta hydrolase 2.0e-12 ●○○○○ -0.69 -0.691988318034756
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0916  NP_230563.1  Q9KTI6  166 aa phosphotyrosine protein phosphatase 1.1e-5 ●○○○○ -0.69 -0.691855349354623
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3316  AIK81873.1  309 aa ribokinase 0.00065 ●○○○○ -0.69 -0.691320727464093
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3342  WP_000442833.1  E8XBB7  ygiC  387 aa glutathionylspermidine synthase family protein 0.004 ●○○○○ -0.69 -0.691143768157056
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3290  WP_000774852.1  E8XAJ0  yghU  288 aa glutathione-dependent disulfide-bond oxidoreductase 0.0012 ●○○○○ -0.69 -0.690732739901931
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2880  AIK81468.1  251 aa ulaR transcriptional repressor 0.0043 ●○○○○ -0.69 -0.69047602886689
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4651  AIK83185.1  771 aa penicillin-binding protein 1C <1e-323 ●○○○○ -0.69 -0.690223275108588
Escherichia coli M12  CO715_14705  ATI06852.1  198 aa 16S rRNA (guanine(966)-N(2))-methyltransferase 0.00075 ●○○○○ -0.69 -0.689901857892268
Escherichia coli M12  CO715_08605  ATI05769.1  128 aa type II toxin-antitoxin system RelE/ParE family toxin 7.3e-25 ●○○○○ -0.69 -0.689693211878019
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0662  NP_230311.1  Q9KU61  437 aa branched-chain amino acid ABC transporter substrate-binding protein 0.00055 ●○○○○ -0.69 -0.689620907052333
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0300  WP_000968384.1  E8XIV3  173 aa DUF2778 domain-containing protein 0.005 ●○○○○ -0.69 -0.689284417360131
Escherichia coli M12  CO715_12680  ATI06485.1  157 aa PTS N-acetylgalactosamine transporter subunit IIB 4.7e-5 ●○○○○ -0.69 -0.689275919849521
Acinetobacter baumannii ATCC 17978  A1S_1913  ABO12340.2  A3M5Z6  argC  349 aa N-acetyl-gamma-glutamyl-phosphate reductase 1.5e-5 ●○○○○ -0.69 -0.689082812967205
Porphyromonas gingivalis ATCC 33277  PGN_1198  WP_012458097.1  B2RK22  486 aa sodium-solute transporter 1.1e-5 ●○○○○ -0.69 -0.688978022935806
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4333  AIK82878.1  351 aa cobalamin synthesis G family protein 2.6e-9 ●○○○○ -0.69 -0.688831101893836
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3159  WP_000968354.1  E8X9I4  340 aa LacI family DNA-binding transcriptional regulator 0.00092 ●○○○○ -0.69 -0.68877912828974
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0459  NP_232851.1  Q9KMB4  186 aa hypothetical protein 3.8e-5 ●○○○○ -0.69 -0.688777443518438
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4803  AIK83330.1  378 aa D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain protein 1.6e-12 ●○○○○ -0.69 -0.688568961422727
Porphyromonas gingivalis ATCC 33277  PGN_1158  WP_005874312.1  B2RJY2  292 aa phosphorylase <1e-323 ●○○○○ -0.69 -0.688469007512751
Escherichia coli M12  CO715_03790  ATI04939.1  322 aa undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase 1.3e-30 ●○○○○ -0.69 -0.688441335792526
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1704  NP_231340.1  Q9KRD8  metE  761 aa 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1.2e-6 ●○○○○ -0.69 -0.688202107675737
Porphyromonas gingivalis ATCC 33277  PGN_0287  WP_012457396.1  B2RHG1  mfa1  563 aa Mfa1 fimbrilin <1e-323 ●○○○○ -0.69 -0.687433369850585
Escherichia coli M12  CO715_13375  ATI06612.1  73 aa hypothetical protein 6.5e-7 ●○○○○ -0.69 -0.687189459707033
Escherichia coli M12  CO715_20345  ATI07867.1  320 aa taurine ABC transporter substrate-binding protein 5.7e-16 ●○○○○ -0.69 -0.686980813692784
Escherichia coli M12  CO715_11160  ATI06211.1  161 aa ATP-independent periplasmic protein-refolding chaperone 1.4e-17 ●○○○○ -0.69 -0.686772167678535
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2431  AIK81028.1  146 aa PTS system fructose IIA component family protein 5.3e-11 ●○○○○ -0.69 -0.686538257660256
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0192  NP_232592.1  Q9KMX4  331 aa D-lactate dehydrogenase 2.2e-5 ●○○○○ -0.69 -0.686276149433261
Porphyromonas gingivalis ATCC 33277  PGN_0566  WP_004585363.1  B2RI90  139 aa acyl-CoA thioesterase <1e-323 ●○○○○ -0.69 -0.686217180838079
Porphyromonas gingivalis ATCC 33277  PGN_0092  WP_004366620.1  B2RGW6  100 aa DNA-binding protein 1.5e-9 ●○○○○ -0.69 -0.686217180838079
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0721  NP_230370.1  Q9KU09  325 aa phosphate ABC transporter substrate-binding protein 0.047 ●○○○○ -0.69 -0.686122099946726
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0705  NP_230354.1  Q9KU24  391 aa chorismate mutase 8.5e-8 ●○○○○ -0.69 -0.686104959880009
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0807  NP_230456.1  Q9KTT1  227 aa hypothetical protein 4.7e-5 ●○○○○ -0.69 -0.68600092696055
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3966  AIK82514.1  98 aa autoinducer 2-degrading protein 2.5e-13 ●○○○○ -0.69 -0.685831521284116
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4031  WP_000078081.1  E8XHU0  yieH  221 aa 6-phosphogluconate phosphatase 0.0023 ●○○○○ -0.69 -0.685739975975903
Escherichia coli M12  CO715_01290  ATI04486.1  387 aa hypothetical protein 6.5e-8 ●○○○○ -0.69 -0.685728937607291
Escherichia coli M12  CO715_07475  ATI05568.1  702 aa bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL 5.6e-41 ●○○○○ -0.69 -0.685311645578793
Escherichia coli M12  CO715_07345  ATI05545.1  597 aa hydrogenase 2 large subunit 9.9e-45 ●○○○○ -0.68 -0.684685707536046
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0061  WP_001181452.1  E8XG80  citC2  348 aa [citrate (pro-3S)-lyase] ligase 0.0059 ●○○○○ -0.68 -0.684388277131355
Escherichia coli M12  CO715_13245  ATI06588.1  481 aa metalloprotease TldD 0.0001 ●○○○○ -0.68 -0.683016539422055
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2851  AIK81440.1  410 aa lacY lactose MFS transporter 9.0e-8 ●○○○○ -0.68 -0.682905434139243
Escherichia coli M12  CO715_10035  ATI06016.1  192 aa phage tail protein 0.027 ●○○○○ -0.68 -0.682599247393558
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5134  AIK83658.1  540 aa alpha/beta hydrolase family protein <1e-323 ●○○○○ -0.68 -0.682394584447884
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2673  NP_232301.1  Q9KNQ8  menA  305 aa 1,4-dihydroxy-2-naphthoate polyprenyltransferase 3.7e-6 ●○○○○ -0.68 -0.682221240633753
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0608  WP_000194140.1  E8X959  entF  1294 aa enterobactin non-ribosomal peptide synthetase EntF 0.0033 ●○○○○ -0.68 -0.681282791709394
Porphyromonas gingivalis ATCC 33277  PGN_0351  WP_012457445.1  B2RHM5  619 aa oxaloacetate decarboxylase <1e-323 ●○○○○ -0.68 -0.681184888204741
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3304  AIK81865.1  328 aa serine/threonine protein kinase <1e-323 ●○○○○ -0.68 -0.68113966814219
Escherichia coli M12  CO715_16990  ATI07262.1  203 aa formate hydrogenlyase subunit 2 9.7e-9 ●○○○○ -0.68 -0.681138725293816
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5153  AIK83674.1  261 aa hypothetical protein <1e-323 ●○○○○ -0.68 -0.680542789780171
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1932  NP_231566.1  Q9KQR6  56 aa hypothetical protein 0.0021 ●○○○○ -0.68 -0.680382700489283
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3803  AIK82353.1  379 aa acrA Membrane Fusion Protein <1e-323 ●○○○○ -0.68 -0.680193310601774
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3252  AIK81813.1  306 aa 1,4-dihydroxy-2-naphthoate octaprenyltransferase <1e-323 ●○○○○ -0.68 -0.679693174879263
Escherichia coli M12  CO715_12465  ATI06447.1  414 aa serine/threonine transporter SstT 1.7e-81 ●○○○○ -0.68 -0.679052265151327
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2251  AIK80856.1  378 aa receptor ligand binding region family protein 5.5e-14 ●○○○○ -0.68 -0.678703073242904
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3512  AIK82068.1  315 aa divergent polysaccharide deacetylase family protein <1e-323 ●○○○○ -0.68 -0.678624833629621
Escherichia coli M12  CO715_19830  ATI07769.1  215 aa DNA-binding transcriptional repressor AcrR 3.8e-27 ●○○○○ -0.68 -0.67842632710858
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3385  AIK81942.1  445 aa dsdX Gnt transporter <1e-323 ●○○○○ -0.68 -0.678281707160214
Acinetobacter baumannii ATCC 17978  A1S_0212  ABO10688.2  371 aa hypothetical protein 1.7e-5 ●○○○○ -0.68 -0.67786851017589
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1555  NP_231195.1  Q9KRT1  170 aa hypothetical protein 4.1e-5 ●○○○○ -0.68 -0.677724893077169
Escherichia coli M12  CO715_12760  ATI06501.1  346 aa permease 2.7e-8 ●○○○○ -0.68 -0.676548512980341
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4240  AIK82785.1  298 aa triose-phosphate Transporter family protein 1.1e-16 ●○○○○ -0.68 -0.675806271525824
Escherichia coli M12  CO715_09490  ATI05924.1  648 aa PTS N-acetyl glucosamine transporter subunit IIABC 2.0e-8 ●○○○○ -0.68 -0.675713928923345
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0170  WP_001022089.1  E8XHV9  kdgT  317 aa 2-keto-3-deoxygluconate permease 1 3.5e-6 ●○○○○ -0.68 -0.67570500572707
Escherichia coli M12  CO715_03815  ATI04944.1  402 aa competence/damage-inducible protein A 0.014 ●○○○○ -0.68 -0.675296636894848
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3760  WP_001098275.1  E8XFA5  dtpB  490 aa dipeptide/tripeptide permease DtpB 0.023 ●○○○○ -0.68 -0.675164106207534
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