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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Acinetobacter baumannii ATCC 17978  A1S_2852  ABO13258.2  401 aa putative thiolase; putative acyl-CoA thiolase 0.0054 ●○○○○ -0.54 -0.540907947243775
Escherichia coli CFT073  c3047  AAN81497.1  A0A0H2VAZ2  sseB  261 aa Protein sseB 0.046 ●○○○○ -0.54 -0.540651078392893
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4264  AIK82809.1  447 aa maltoporin periplasmic N-terminal extension family protein 1.1e-7 ●○○○○ -0.54 -0.539742040849491
Escherichia coli M12  CO715_12985  ATI06541.1  211 aa phospholipid-binding protein 2.0e-5 ●○○○○ -0.54 -0.539676727633088
Acinetobacter baumannii ATCC 17978  A1S_1888  ABO12315.1  322 aa putative transport protein 0.013 ●○○○○ -0.54 -0.53927685485338
Escherichia coli M12  CO715_07480  ATI05569.1  369 aa hypothetical protein 5.1e-12 ●○○○○ -0.54 -0.538842143576092
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2515  NP_232144.1  Q9KP61  84 aa BolA/YrbA family protein 5.0e-5 ●○○○○ -0.54 -0.538250607302626
Escherichia coli M12  CO715_09640  ATI05946.1  184 aa sel1 repeat family protein 2.1e-17 ●○○○○ -0.54 -0.538216205533346
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4539  AIK83077.1  282 aa bacterial extracellular solute-binding, 3 familyprotein 0.00016 ●○○○○ -0.54 -0.537501396047818
Escherichia coli M12  CO715_21790  ATI08129.1  321 aa sugar kinase 1.8e-23 ●○○○○ -0.54 -0.53738162147635
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0438  NP_230092.1  Q9KUS7  289 aa hypothetical protein 2.2e-7 ●○○○○ -0.54 -0.537142727840482
Porphyromonas gingivalis ATCC 33277  PGN_0387  WP_012457470.1  B2RHR1  216 aa O-methyltransferase <1e-323 ●○○○○ -0.54 -0.535872826141354
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1611  AIK80231.1  561 aa aspT/YidE/YbjL antiporter duplication domain protein 4.0e-6 ●○○○○ -0.53 -0.534439942448454
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2277  AIK80882.1  188 aa nlpC/P60 family protein 0.036 ●○○○○ -0.53 -0.534174547745022
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3911  AIK82459.1  335 aa luciferase oxidoreductase, group 1 family protein <1e-323 ●○○○○ -0.53 -0.534039704108892
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3270  AIK81831.1  334 aa branched-chain amino acid transport system / permease component family protein 2.4e-14 ●○○○○ -0.53 -0.533958943286063
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0171  NP_232571.1  Q9KMZ5  646 aa hypothetical protein 0.0019 ●○○○○ -0.53 -0.533866032103425
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1817  AIK80430.1  895 aa kdpD, KdpD-Phis 6.9e-6 ●○○○○ -0.53 -0.533388455726107
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0341  NP_232737.1  Q9K3D3  132 aa biphenyl-2,3-diol 1,2-dioxygenase 0.00057 ●○○○○ -0.53 -0.533297523000655
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5158  AIK83679.1  327 aa bacterial regulatory, gntR family protein 0.012 ●○○○○ -0.53 -0.533089918877519
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2007  NP_231641.1  Q9KQJ1  405 aa ROK family transcriptional regulator 2.4e-5 ●○○○○ -0.53 -0.532839562007034
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4863  AIK83390.1  401 aa L-rhamnonate dehydratase <1e-323 ●○○○○ -0.53 -0.53261000472827
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1347  NP_230991.1  Q9KSB2  maiA  215 aa glutathione S-transferase 1.4e-5 ●○○○○ -0.53 -0.532335422938699
Acinetobacter baumannii ATCC 17978  A1S_1682  ABO12109.2  361 aa putative poly(R)-hydroxyalkanoic acid synthase 0.042 ●○○○○ -0.53 -0.532254629967803
Escherichia coli M12  CO715_24485  ATI08589.1  256 aa putative lateral flagellar export/assembly protein LafU 0.0044 ●○○○○ -0.53 -0.531539533077382
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2711  AIK81301.1  242 aa merR regulatory family protein 2.7e-7 ●○○○○ -0.53 -0.531003783290917
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1494  NP_231135.1  Q9KRY9  868 aa aminopeptidase 6.2e-6 ●○○○○ -0.53 -0.53092597760199
Acinetobacter baumannii ATCC 17978  A1S_2835  ABO13241.2  611 aa GTP-binding elongation factor family protein 0.00037 ●○○○○ -0.53 -0.530776632747612
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4802  WP_000811635.1  E8XDD0  223 aa Crp/Fnr family transcriptional regulator 0.0074 ●○○○○ -0.53 -0.530598978173029
Escherichia coli M12  CO715_17235  ATI07307.1  259 aa electron transfer flavoprotein 2.0e-5 ●○○○○ -0.53 -0.530287656991889
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0884  NP_233270.1  Q9KL63  353 aa hypothetical protein 0.00052 ●○○○○ -0.53 -0.530238420646211
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4182  AIK82727.1  440 aa sel1 repeat family protein <1e-323 ●○○○○ -0.53 -0.530126822220152
Escherichia coli M12  CO715_05675  ATI05260.1  121 aa host cell division inhibitor Icd-like protein 4.4e-14 ●○○○○ -0.53 -0.53007901097764
Escherichia coli M12  CO715_09600  ATI05939.1  302 aa amino acid ABC transporter substrate-binding protein 0.0017 ●○○○○ -0.53 -0.529035780906396
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4274  AIK82819.1  445 aa PTS system, lactose/cellobiose IIC component family protein <1e-323 ●○○○○ -0.53 -0.528927607205362
Escherichia coli M12  CO715_02910  ATI04779.1  350 aa AraC family transcriptional regulator 2.2e-9 ●○○○○ -0.53 -0.528827134892147
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0804  NP_233190.1  Q9KLE2  deaD  663 aa ATP-dependent RNA helicase DeaD 0.00031 ●○○○○ -0.53 -0.528495473248413
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3566  AIK82122.1  452 aa ankyrin repeat family protein <1e-323 ●○○○○ -0.53 -0.528195385862833
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4325  AIK82870.1  303 aa bacterial regulatory helix-turn-helix, AraC family protein 6.0e-5 ●○○○○ -0.53 -0.527487064330294
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4597  AIK83131.1  361 aa RNA 2'-O ribose methyltransferase substrate binding family protein 0.011 ●○○○○ -0.53 -0.527401802694058
Acinetobacter baumannii ATCC 17978  A1S_0873  ABO11305.2  A3M311  bpt  271 aa putative arginine-tRNA-protein transferase 0.0007 ●○○○○ -0.53 -0.527379581620932
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1773  NP_231408.1  Q9KR70  356 aa hypothetical protein 6.9e-6 ●○○○○ -0.53 -0.527354460284233
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2588  WP_001279831.1  E8XGH6  ypfI  672 aa tRNA cytosine(34) acetyltransferase TmcA 0.031 ●○○○○ -0.53 -0.527283651693239
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3653  AIK82208.1  255 aa ABC transporter family protein 0.0028 ●○○○○ -0.53 -0.52725524636805
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4471  WP_000083882.1  E8X9S6  acs  652 aa acetate--CoA ligase 0.02 ●○○○○ -0.53 -0.526952601021253
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2172  AIK80777.1  454 aa sugar (and other) transporter family protein 2.4e-12 ●○○○○ -0.53 -0.526547383806416
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4307  AIK82852.1  408 aa rnfC Barrel sandwich hybrid domain protein 4.5e-5 ●○○○○ -0.53 -0.526388597262079
Acinetobacter baumannii ATCC 17978  A1S_2049  ABO12476.1  199 aa hypothetical protein 0.00074 ●○○○○ -0.52 -0.523905768378905
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3272  AIK81833.1  104 aa L-rhamnose 1-epimerase <1e-323 ●○○○○ -0.52 -0.523822438973835
Escherichia coli M12  CO715_18045  ATI07452.1  200 aa 5-formyltetrahydrofolate cyclo-ligase 0.00013 ●○○○○ -0.52 -0.523819630550174
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2028  NP_231662.1  Q9KQH0  rluC  315 aa ribosomal large subunit pseudouridine synthase C 5.8e-7 ●○○○○ -0.52 -0.523268961193184
Escherichia coli M12  CO715_17045  ATI07271.1  853 aa DNA mismatch repair protein MutS 5.1e-118 ●○○○○ -0.52 -0.523193692507428
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1441  NP_231084.1  Q9KS20  206 aa cbb3-type cytochrome c oxidase subunit II 0.0023 ●○○○○ -0.52 -0.522849913338229
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2005  AIK80611.1  494 aa feaB 1.6e-7 ●○○○○ -0.52 -0.522708215068277
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2625  NP_232253.1  Q9KNV5  236 aa ribulose-phosphate 3-epimerase 0.0048 ●○○○○ -0.52 -0.521959779771704
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3660  AIK82215.1  356 aa ugpC 9.4e-11 ●○○○○ -0.52 -0.521368481852737
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0131  NP_232532.1  Q9KN34  rbsK  306 aa ribokinase 0.01 ●○○○○ -0.52 -0.521217765816894
Porphyromonas gingivalis ATCC 33277  PGN_2065  WP_012458726.1  B2RMI8  293 aa hypothetical protein <1e-323 ●○○○○ -0.52 -0.521073853025529
Escherichia coli M12  CO715_03125  ATI04815.1  418 aa ion channel protein 2.8e-19 ●○○○○ -0.52 -0.520689940336441
Acinetobacter baumannii ATCC 17978  A1S_2289  ABO12712.2  119 aa putative signal peptide 0.0026 ●○○○○ -0.52 -0.519923517399998
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0682  WP_001207419.1  E8XA20  rihA  311 aa pyrimidine-specific ribonucleoside hydrolase RihA 0.012 ●○○○○ -0.52 -0.519634951289225
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4653  AIK83187.1  388 aa 23S rRNA m2A2503 methyltransferase 6.4e-9 ●○○○○ -0.52 -0.519588098582954
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2331  AIK80935.1  814 aa acyl-CoA dehydrogenase, C-terminal domain protein <1e-323 ●○○○○ -0.52 -0.519382793706572
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0289  NP_229944.1  Q9KV68  332 aa gluconate utilization system gnt-I transcriptional repressor 1.7e-5 ●○○○○ -0.52 -0.519289969900987
Escherichia coli M12  CO715_00275  ATI04307.1  282 aa MurR/RpiR family transcriptional regulator 4.5e-5 ●○○○○ -0.52 -0.518812126208202
Porphyromonas gingivalis ATCC 33277  PGN_0349  WP_004583895.1  B2RHM3  ustA  84 aa hypothetical protein <1e-323 ●○○○○ -0.52 -0.518709679533095
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3155  WP_000558962.1  E8X9I0  tas  346 aa NADP(H)-dependent aldo-keto reductase 0.019 ●○○○○ -0.52 -0.518250932892927
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2299  NP_231930.1  Q9KPR7  194 aa peptidyl-prolyl cis-trans isomerase A 3.6e-6 ●○○○○ -0.52 -0.518093900097339
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0533  NP_230184.1  Q9KUI7  311 aa lipoprotein NlpD 1.3e-6 ●○○○○ -0.52 -0.517624475282905
Porphyromonas gingivalis ATCC 33277  PGN_1092  WP_012458020.1  B2RJR6  471 aa helicase 3.9e-7 ●○○○○ -0.52 -0.517475352635601
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2231  WP_001012658.1  E8XCY4  321 aa sugar kinase 0.035 ●○○○○ -0.52 -0.517469366312954
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1167  NP_230812.1  Q9KST9  tdk  192 aa thymidine kinase 6.1e-5 ●○○○○ -0.52 -0.517412165563194
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3253  WP_000252197.1  E8XAF4  yggM  335 aa DUF1202 domain-containing protein 0.026 ●○○○○ -0.52 -0.517410234542086
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1459  NP_231102.1  P38441  ace  97 aa accessory cholera enterotoxin 5.6e-5 ●○○○○ -0.52 -0.516870982835032
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2113  AIK80719.1  47 aa ribosomal protein L36 3.7e-10 ●○○○○ -0.52 -0.516706386803599
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2419  AIK81016.1  266 aa type 4 prepilin-like proteins leader peptide-processing enzyme 9.6e-10 ●○○○○ -0.52 -0.516435184168627
Porphyromonas gingivalis ATCC 33277  PGN_0025  WP_005874467.1  B2RGP9  180 aa TrmH family RNA methyltransferase <1e-323 ●○○○○ -0.52 -0.516018825119867
Escherichia coli M12  CO715_02845  ATI04768.1  267 aa ethanolamine utilization cob(I)yrinic acid a,c-diamide adenosyltransferase EutT 1.5e-7 ●○○○○ -0.52 -0.51547378998022
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4530  AIK83068.1  173 aa fimbrial family protein 1.0e-6 ●○○○○ -0.51 -0.514675295416936
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1923  NP_231557.1  Q9KQS5  tig  433 aa trigger factor 0.0067 ●○○○○ -0.51 -0.514163761279724
Acinetobacter baumannii ATCC 17978  A1S_3329  ABO13718.2  230 aa EsvJ 0.00092 ●○○○○ -0.51 -0.514054464721178
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3275  AIK81836.1  331 aa HTH-type transcriptional regulator rafR <1e-323 ●○○○○ -0.51 -0.513756147189022
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3338  AIK81895.1  55 aa hypothetical protein <1e-323 ●○○○○ -0.51 -0.513748536740732
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2662  NP_232290.1  Q9KNR9  191 aa hypothetical protein 0.00087 ●○○○○ -0.51 -0.513325658260068
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0507  NP_232898.1  Q9K344  114 aa transposase OrfAB subunit A 0.0006 ●○○○○ -0.51 -0.513143444808135
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4518  AIK83056.1  132 aa putative inner membrane protein 2.1e-12 ●○○○○ -0.51 -0.513074384582407
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3003  AIK81588.1  449 aa permease family protein 1.8e-7 ●○○○○ -0.51 -0.512872894759008
Escherichia coli M12  CO715_23275  ATI08387.1  73 aa hypothetical protein 7.0e-30 ●○○○○ -0.51 -0.512761391794985
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0076  NP_232477.1  Q9KN89  458 aa hypothetical protein 5.6e-5 ●○○○○ -0.51 -0.512253587146022
Acinetobacter baumannii ATCC 17978  A1S_0268  ABO10743.1  108 aa putative DNA binding protein 0.029 ●○○○○ -0.51 -0.512119054748917
Porphyromonas gingivalis ATCC 33277  PGN_1795  WP_004583528.1  B2RLR9  148 aa hypothetical protein <1e-323 ●○○○○ -0.51 -0.511696492373527
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3771  WP_000934257.1  E8XFB6  treF  549 aa alpha,alpha-trehalase TreF 0.018 ●○○○○ -0.51 -0.51152072730106
Escherichia coli M12  CO715_18135  ATI07467.1  291 aa mechanosensitive ion channel protein MscS 7.0e-41 ●○○○○ -0.51 -0.511509515709491
Escherichia coli M12  CO715_19435  ATI07699.1  321 aa antimicrobial peptide ABC transporter permease SapB 0.00061 ●○○○○ -0.51 -0.511092223680994
Escherichia coli M12  CO715_13670  ATI06662.1  334 aa ornithine carbamoyltransferase 0.0016 ●○○○○ -0.51 -0.510257639623998
Escherichia coli M12  CO715_14425  ATI06798.1  250 aa ribosomal RNA small subunit methyltransferase J 0.0097 ●○○○○ -0.51 -0.51004899360975
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2493  AIK81090.1  523 aa 2-isopropylmalate synthase <1e-323 ●○○○○ -0.51 -0.509915870118097
Escherichia coli M12  CO715_19470  ATI07706.1  375 aa CMD domain-containing protein 1.5e-7 ●○○○○ -0.51 -0.509840347595501
Escherichia coli M12  CO715_21980  ATI08164.1  162 aa colanic acid biosynthesis acetyltransferase WcaB 1.1e-5 ●○○○○ -0.51 -0.509840347595501
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0779  NP_233165.1  Q9KLG5  477 aa hypothetical protein 4.5e-5 ●○○○○ -0.51 -0.509672767667534
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