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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4233  WP_000378721.1  E8XKB8  227 aa hypothetical protein 4.0e-5 ●●○○○ -1.31 -1.31448383047922
Acinetobacter baumannii ATCC 17978  A1S_1980  ABO12407.2  A3M663  argF  306 aa ornithine carbamoyltransferase 3.6e-15 ●●○○○ -1.31 -1.31356214703066
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2663  WP_000100008.1  E8XGQ0  cadB  443 aa cadaverine/lysine antiporter 1.4e-8 ●●○○○ -1.31 -1.31330400922835
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1590  NP_231230.1  Q9KRP6  567 aa acetolactate synthase 1.8e-8 ●●○○○ -1.31 -1.31297841268571
Escherichia coli M12  CO715_08240  ATI05703.1  287 aa dimethyl sulfoxide reductase anchor subunit 0.00012 ●●○○○ -1.31 -1.31250156441087
Escherichia coli M12  CO715_02635  ATI04728.1  208 aa uracil phosphoribosyltransferase 0.00077 ●●○○○ -1.31 -1.31229291839662
Escherichia coli M12  CO715_02935  ATI04783.1  191 aa RpoE-regulated lipoprotein 2.2e-33 ●●○○○ -1.31 -1.31208427238237
Escherichia coli M12  CO715_03185  ATI04827.1  80 aa DUF2545 domain-containing protein 1.5e-6 ●●○○○ -1.31 -1.31187562636812
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0202  WP_001205357.1  E8XHZ1  fhuD  296 aa Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD 0.0076 ●●○○○ -1.31 -1.31181409892495
Escherichia coli M12  CO715_22780  ATI08303.1  343 aa 16S rRNA methyltransferase 7.8e-19 ●●○○○ -1.31 -1.31145833433963
Acinetobacter baumannii ATCC 17978  A1S_1598  ABO12025.2  952 aa hypothetical protein 7.2e-15 ●●○○○ -1.31 -1.31137392068368
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0918  NP_230565.1  Q9KTI4  413 aa UDP-N-acetyl-D-mannosamine dehydrogenase 1.4e-9 ●●○○○ -1.31 -1.3111723247049
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3371  WP_000094651.1  E8XBE5  aer  506 aa PAS domain-containing methyl-accepting chemotaxis protein 0.0042 ●●○○○ -1.31 -1.31022782458165
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2178  NP_231809.1  Q9KQ26  prmC  286 aa protein-(glutamine-N5) methyltransferase HemK 2.0e-6 ●●○○○ -1.31 -1.30992107074252
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0277  NP_232674.1  Q9KMP5  gcvH  126 aa glycine cleavage system protein H 3.8e-8 ●●○○○ -1.31 -1.30974080652968
Escherichia coli M12  CO715_07195  ATI05521.1  378 aa Fe3+/spermidine/putrescine ABC transporter ATP-binding protein 3.4e-19 ●●○○○ -1.31 -1.30916322818289
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0958  NP_233342.1  Q9KKZ2  505 aa hypothetical protein 1.4e-6 ●●○○○ -1.31 -1.30698796989746
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2060  CBW18156.1  A0A0H3NN75  rfbK  477 aa phosphomannomutase 0.015 ●●○○○ -1.31 -1.30666410778647
Acinetobacter baumannii ATCC 17978  A1S_2459  ABO12877.2  356 aa putative oxidoreductase 0.0011 ●●○○○ -1.31 -1.30635559268173
Escherichia coli M12  CO715_24490  ATI08590.1  351 aa DNA polymerase IV 1.3e-19 ●●○○○ -1.31 -1.30603353796916
Escherichia coli M12  CO715_19485  ATI07709.1  661 aa cyclic di-GMP phosphodiesterase 2.0e-15 ●●○○○ -1.31 -1.30603353796916
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2645  NP_232273.1  Q9KNT5  argE  378 aa acetylornithine deacetylase 7.0e-10 ●●○○○ -1.31 -1.3057870410401
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1527  NP_231167.1  Q9KRV7  606 aa bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MoeA 0.0004 ●●○○○ -1.31 -1.30573174673361
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3050  AIK81635.1  95 aa putative cheW domain protein 2.3e-8 ●●○○○ -1.31 -1.30571508088476
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0014  CBW16115.1  A0A0H3NGX9  315 aa hypothetical regulatory protein 0.0089 ●●○○○ -1.31 -1.30546580659014
Escherichia coli M12  CO715_06720  ATI05435.1  422 aa DNA polymerase V subunit UmuC 1.6e-27 ●●○○○ -1.3 -1.30457301586941
Escherichia coli M12  CO715_21635  ATI08099.1  308 aa ATP-binding protein 6.7e-31 ●●○○○ -1.3 -1.30436436985516
Escherichia coli M12  CO715_10455  ATI06081.1  548 aa fumarate hydratase class I, aerobic 1.8e-22 ●●○○○ -1.3 -1.30415572384092
Escherichia coli M12  CO715_20380  ATI07873.1  277 aa S-formylglutathione hydrolase 4.0e-22 ●●○○○ -1.3 -1.30332113978392
Escherichia coli M12  CO715_11850  ATI06338.1  470 aa cell division protein FtsP 1.2e-24 ●●○○○ -1.3 -1.30290384775542
Acinetobacter baumannii ATCC 17978  A1S_3204  ABO13597.2  610 aa septum formation penicillin binding protein 3, peptidoglycan synthetase 0.05 ●●○○○ -1.3 -1.30279953328917
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0433  WP_000198484.1  E8XKK0  yaji  179 aa DUF3251 domain-containing protein 9.9e-13 ●●○○○ -1.3 -1.30239162819369
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2848  WP_000698372.1  E8XJ74  125 aa ASCH domain-containing protein 0.011 ●●○○○ -1.3 -1.30227233588949
Escherichia coli M12  CO715_06320  ATI05367.1  486 aa cardiolipin synthase A 1.3e-62 ●●○○○ -1.3 -1.30186061768418
Acinetobacter baumannii ATCC 17978  A1S_1001  ABO11433.2  537 aa ATP-sulfurylase subunit 1 2.6e-10 ●●○○○ -1.3 -1.30185958571738
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4339  AIK82884.1  93 aa cobalt transport family protein 0.0015 ●●○○○ -1.3 -1.30117788583416
Escherichia coli M12  CO715_18490  ATI07530.1  422 aa L-2-hydroxyglutarate oxidase 0.00063 ●●○○○ -1.3 -1.30102603362718
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0956  NP_233340.1  Q9KKZ4  vdcA  339 aa diguanylate cyclase 2.7e-6 ●●○○○ -1.3 -1.30079489953649
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4368  AIK82911.1  340 aa ABC transporter family protein 4.2e-9 ●●○○○ -1.3 -1.3003434921054
Escherichia coli M12  CO715_22760  ATI08299.1  529 aa peptide chain release factor 3 2.7e-12 ●●○○○ -1.3 -1.30019144957019
Escherichia coli M12  CO715_05795  ATI05280.1  117 aa phage tail protein 3.3e-12 ●●○○○ -1.3 -1.30019144957019
Escherichia coli M12  CO715_16810  ATI07233.1  518 aa glutamate--cysteine ligase 0.00029 ●●○○○ -1.3 -1.29977415754169
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3863  WP_001079584.1  E8XG05  1461 aa autotransporter adhesin SadA 6.1e-5 ●●○○○ -1.3 -1.29916601437082
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0269  NP_229925.1  Q9KV87  399 aa mannose-6-phosphate isomerase 3.5e-8 ●●○○○ -1.3 -1.29860377373959
Escherichia coli M12  CO715_04780  ATI05109.1  222 aa SOS response-associated peptidase 2.1e-16 ●●○○○ -1.3 -1.29831363544195
Escherichia coli M12  CO715_03685  ATI04921.1  613 aa NADH-quinone oxidoreductase subunit L 0.00088 ●●○○○ -1.3 -1.29831363544195
Escherichia coli M12  CO715_10660  ATI06117.1  365 aa alkene reductase 2.3e-5 ●●○○○ -1.3 -1.29789634341345
Acinetobacter baumannii ATCC 17978  A1S_2056  ABO12483.2  702 aa DNA polymerase III tau and gamma subunits (DNA elongation factor III) 0.0021 ●●○○○ -1.3 -1.29772100012664
Porphyromonas gingivalis ATCC 33277  PGN_0199  WP_012457321.1  B2RH73  61 aa hypothetical protein <1e-323 ●●○○○ -1.3 -1.29765635956299
Escherichia coli M12  CO715_24265  ATI08552.1  155 aa ribonuclease HI 0.01 ●●○○○ -1.3 -1.29747905138495
Escherichia coli M12  CO715_04865  ATI05122.1  890 aa phosphotransferase RcsD 2.9e-17 ●●○○○ -1.3 -1.29664446732796
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0741  CBW16839.2  A0A0H3NEE8  308 aa LysR-family transcriptional regulator 0.039 ●●○○○ -1.3 -1.29613216567588
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3029  CBW19128.1  A0A0H3NRH8  gcvP  957 aa Glycine dehydrogenase [decarboxylating] 0.024 ●●○○○ -1.3 -1.29569223681421
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3258  CBW19354.1  A0A0H3NI71  rbfA  133 aa ribosome-binding factor A (P15B protein) 0.01 ●●○○○ -1.29 -1.29466607568656
Porphyromonas gingivalis ATCC 33277  PGN_1080  WP_012458011.1  B2RJQ4  339 aa branched-chain amino acid aminotransferase 0.0036 ●●○○○ -1.29 -1.29458948892059
Escherichia coli M12  CO715_11640  ATI06299.1  205 aa glycerol-3-phosphate acyltransferase 2.8e-12 ●●○○○ -1.29 -1.29414071515697
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3052  CBW19151.1  A0A0H3NLW5  tktA  648 aa transketolase 0.022 ●●○○○ -1.29 -1.29413916209939
Escherichia coli M12  CO715_03865  ATI04952.1  78 aa ferrous iron transporter C 3.7e-8 ●●○○○ -1.29 -1.29330613109997
Escherichia coli M12  CO715_22550  ATI08263.1  237 aa hypothetical protein 2.3e-14 ●●○○○ -1.29 -1.29309748508573
Escherichia coli M12  CO715_07910  ATI05642.1  101 aa hypothetical protein 3.0e-14 ●●○○○ -1.29 -1.29309748508573
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3160  CBW19259.1  A0A0H3NI01  tolC  491 aa outer membrane protein TolC precursor 0.046 ●●○○○ -1.29 -1.29295206917289
Escherichia coli M12  CO715_07760  ATI05616.1  317 aa protein FecR 5.2e-87 ●●○○○ -1.29 -1.29268019305723
Escherichia coli M12  CO715_20395  ATI07876.1  337 aa 4-hydroxy-2-oxovalerate aldolase 2.7e-24 ●●○○○ -1.29 -1.29226290102873
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4501  WP_077248243.1  E8X9V6  799 aa dimethyl sulfoxide reductase subunit A 3.4e-8 ●●○○○ -1.29 -1.29149394999745
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2432  AIK81029.1  255 aa ABC-2 type transporter family protein 1.3e-12 ●●○○○ -1.29 -1.29117152795504
Escherichia coli M12  CO715_12530  ATI06458.1  328 aa glutathione S-transferase family protein 4.2e-12 ●●○○○ -1.29 -1.29080237892899
Escherichia coli M12  CO715_17965  ATI07438.1  135 aa hypothetical protein 6.1e-50 ●●○○○ -1.29 -1.29059373291474
Acinetobacter baumannii ATCC 17978  A1S_1724  ABO12151.2  428 aa dicarboxylic acid transport protein; alpha-ketoglutarate permease (MFS superfamily) 1.1e-14 ●●○○○ -1.29 -1.28924696192296
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2663  CBW18765.1  A0A0H3NQ78  726 aa hypothetical type I secretion protein, ATP-binding protein 0.015 ●●○○○ -1.29 -1.28904518050574
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1502  CBW17596.1  A0A0H3NGS1  yddG  274 aa hypothetical integral membrane protein 0.012 ●●○○○ -1.29 -1.28818602985417
Escherichia coli M12  CO715_20900  ATI07967.1  547 aa flagellar hook-associated protein FlgK 7.0e-15 ●●○○○ -1.29 -1.28808998074375
Escherichia coli M12  CO715_11245  ATI06227.1  135 aa NTP pyrophosphohydrolase 4.3e-6 ●●○○○ -1.29 -1.28808998074375
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0193  WP_000174614.1  E8XHY2  pcnB  472 aa polynucleotide adenylyltransferase PcnB 0.039 ●●○○○ -1.29 -1.28727876067912
Escherichia coli M12  CO715_01275  ATI04483.1  109 aa biofilm peroxide resistance protein BsmA 3.9e-13 ●●○○○ -1.29 -1.28662945864401
Escherichia coli M12  CO715_12945  ATI06534.1  321 aa EamA family transporter 1.3e-9 ●●○○○ -1.29 -1.28537758255852
Escherichia coli M12  CO715_10825  ATI06147.1  423 aa signal peptide peptidase SppA 7.6e-22 ●●○○○ -1.29 -1.28516893654427
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3049  AIK81634.1  369 aa malK <1e-323 ●●○○○ -1.29 -1.28504996583458
Escherichia coli M12  CO715_03370  ATI04859.1  161 aa phosphohistidine phosphatase 1.0e-6 ●●○○○ -1.28 -1.28496029053002
Escherichia coli M12  CO715_10740  ATI06133.1  418 aa hypothetical protein 0.00087 ●●○○○ -1.28 -1.28496029053002
Escherichia coli CFT073  c1928  AAN80386.1  Q8FHG0  ydeO  253 aa Hypothetical transcriptional regulator ydeO 0.045 ●●○○○ -1.28 -1.28438995791605
Escherichia coli M12  CO715_07705  ATI05609.1  115 aa IS66 family insertion sequence hypothetical protein 1.7e-46 ●●○○○ -1.28 -1.28433435248727
Escherichia coli M12  CO715_22455  ATI08248.1  62 aa hypothetical protein 1.7e-16 ●●○○○ -1.28 -1.28433435248727
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0589  WP_001520101.1  E8X940  ybdg  60 aa hypothetical protein 4.9e-8 ●●○○○ -1.28 -1.28371778067893
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2225  AIK80831.1  140 aa hypothetical protein 0.003 ●●○○○ -1.28 -1.28296209468189
Escherichia coli M12  CO715_02860  ATI04770.1  95 aa ethanolamine utilization protein EutN 8.2e-22 ●●○○○ -1.28 -1.28287383038753
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1361  AIK79984.1  336 aa beta-hexosaminidase 7.0e-8 ●●○○○ -1.28 -1.28264174631499
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3392  AIK81949.1  95 aa ilvN <1e-323 ●●○○○ -1.28 -1.28225944618768
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1714  NP_231350.1  Q9KRC8  mukB  1491 aa cell division protein MukB 1.9e-8 ●●○○○ -1.28 -1.28119287834429
Escherichia coli M12  CO715_13560  ATI06642.1  210 aa serine recombinase 2.0e-32 ●●○○○ -1.28 -1.28099601625929
Escherichia coli M12  CO715_20545  ATI07903.1  196 aa nitroreductase family protein 3.1e-5 ●●○○○ -1.28 -1.28078737024504
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2977  WP_000010814.1  E8XK78  ygaA  506 aa nitric oxide reductase transcriptional regulator NorR 1.9e-7 ●●○○○ -1.28 -1.28071100608009
Escherichia coli M12  CO715_03340  ATI04854.1  415 aa hypothetical protein 1.0e-39 ●●○○○ -1.28 -1.28057872423079
Escherichia coli M12  CO715_14530  ATI06819.1  133 aa nickel-responsive transcriptional regulator NikR 3.9e-13 ●●○○○ -1.28 -1.27995278618805
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0047  CBW16148.1  A0A0H3NCJ4  ileS  944 aa isoleucyl-tRNA synthetase 0.0061 ●●○○○ -1.28 -1.27947155803399
Escherichia coli M12  CO715_00500  ATI04346.1  274 aa protein bax 1.2e-24 ●●○○○ -1.28 -1.27849226408831
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3054  CBW19153.1  A0A0H3NRN3  speB  306 aa Agmatinase 0.0066 ●●○○○ -1.28 -1.27817739865687
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1738  AIK80358.1  318 aa formimidoylglutamase 0.016 ●●○○○ -1.28 -1.27808780558371
Escherichia coli M12  CO715_23060  ATI08353.1  241 aa molecular chaperone FimC 3.3e-29 ●●○○○ -1.28 -1.27807497205981
Escherichia coli M12  CO715_19675  ATI07742.1  179 aa intracellular septation protein A 1.2e-6 ●●○○○ -1.28 -1.27682309597431
Escherichia coli M12  CO715_08330  ATI05718.1  106 aa ATP-dependent Clp protease adaptor ClpS 2.2e-17 ●●○○○ -1.28 -1.27661444996007
Retrieved entries 3,301–3,400 out of 36,363 total in 656.7 ms (Link to these results)