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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0076  WP_000347134.1  E8XG94  caiA  380 aa crotonobetainyl-CoA dehydrogenase 0.02 ○○○○○ 1.21 1.21497903965457
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1035  AIK79658.1  262 aa phenylacetate degradation putative enoyl-CoA hydratase PaaB 2.1e-14 ○○○○○ 1.22 1.21587718688932
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5068  AIK83594.1  304 aa bacterial regulatory helix-turn-helix, lysR family protein 0.00016 ○○○○○ 1.22 1.21703170250951
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0267  WP_000648534.1  E8XIS1  yafC  304 aa LysR family transcriptional regulator 0.0073 ○○○○○ 1.22 1.21909461142627
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4057  WP_000956588.1  E8XIJ8  yieM  483 aa ATPase RavA stimulator ViaA 0.012 ○○○○○ 1.22 1.2194109686075
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1678  AIK80298.1  271 aa putative L,D-transpeptidase YbiS <1e-323 ○○○○○ 1.22 1.21947855823993
Escherichia coli M12  CO715_24515  ATI08594.1  204 aa peptide chain release factor H 0.012 ○○○○○ 1.22 1.22025240255606
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1226  AIK79849.1  452 aa PTS system, cellobiose-specific IIC component 3.1e-12 ○○○○○ 1.22 1.2207985349389
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0413  NP_230067.1  Q9KUV1  143 aa hypothetical protein 0.0062 ○○○○○ 1.22 1.22092122225459
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2214  WP_001197805.1  E8XCW7  yegN  1040 aa multidrug efflux RND transporter permease subunit MdtB 0.012 ○○○○○ 1.22 1.22092797675312
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1131  AIK79754.1  198 aa hypothetical protein 0.00039 ○○○○○ 1.22 1.22271102080171
Acinetobacter baumannii ATCC 17978  A1S_0624  ABO11073.2  264 aa putative lipoprotein 2.2e-6 ○○○○○ 1.22 1.22329978402517
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4776  WP_000841604.1  E8XDA4  190 aa outer membrane protein 0.01 ○○○○○ 1.22 1.22429038118975
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1741  AIK80361.1  895 aa HAD ATPase, P-type, IC family protein <1e-323 ○○○○○ 1.22 1.22434408298772
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4851  AIK83378.1  153 aa hypothetical protein 0.00012 ○○○○○ 1.22 1.22495276528692
Escherichia coli M12  CO715_13920  ATI06707.1  212 aa hypothetical protein 5.5e-47 ○○○○○ 1.23 1.22588584494078
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3896  AIK82445.1  41 aa hypothetical protein 8.4e-8 ○○○○○ 1.23 1.22621230231744
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4904  AIK83430.1  585 aa helicase conserved C-terminal domain protein <1e-323 ○○○○○ 1.23 1.22708173467173
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4687  AIK83221.1  297 aa beta-glucoside kinase <1e-323 ○○○○○ 1.23 1.22810052106478
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1470  AIK80091.1  765 aa glycerol dehydratase <1e-323 ○○○○○ 1.23 1.22978933106392
Acinetobacter baumannii ATCC 17978  A1S_2082  ABO12509.2  184 aa putative transcriptional regulator 3.3e-5 ○○○○○ 1.23 1.23113512116943
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4346  WP_000944073.1  E8XLA6  thiG  256 aa thiazole synthase 0.0092 ○○○○○ 1.23 1.23128628481168
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1267  AIK79890.1  644 aa protein kinase <1e-323 ○○○○○ 1.23 1.23186054776014
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2420  CBW18522.1  A0A0H3NFN5  eutC  298 aa Ethanolamine ammonia-lyase light chain 0.0081 ○○○○○ 1.23 1.23238803164398
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0156  WP_000024779.1  E8XH59  316 aa alpha-N-arabinofuranosidase 0.01 ○○○○○ 1.23 1.23311230131589
Acinetobacter baumannii ATCC 17978  A1S_2735  ABO13148.2  415 aa AdeI 0.0023 ○○○○○ 1.23 1.23315433260092
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2858  AIK81447.1  123 aa hxlR-like helix-turn-helix family protein <1e-323 ○○○○○ 1.23 1.23320995010269
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1024  AIK79647.1  459 aa efflux transporter, outer membrane factor (OMF) lipo, NodT family protein <1e-323 ○○○○○ 1.23 1.23336170574627
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3186  AIK81754.1  293 aa glucose-1-phosphate thymidylyltransferase <1e-323 ○○○○○ 1.23 1.23395625373015
Acinetobacter baumannii ATCC 17978  A1S_0669  ABO11117.1  173 aa Bile acid:sodium symporter 0.0012 ○○○○○ 1.23 1.23468399913742
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1809  AIK80422.1  218 aa allophanate hydrolase subunit 1 family protein <1e-323 ○○○○○ 1.23 1.23494894643642
Acinetobacter baumannii ATCC 17978  A1S_1706  ABO12133.1  214 aa putative membrane protein 0.00012 ○○○○○ 1.24 1.23620958369327
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1041  AIK79664.1  309 aa phenylacetic acid catabolic family protein 6.3e-15 ○○○○○ 1.24 1.23625466652385
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0737  NP_233124.1  Q9KLK6  luxP  364 aa luxP protein 0.0033 ○○○○○ 1.24 1.23716653618278
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0441  WP_001199859.1  E8XKK8  yajO  324 aa aldo/keto reductase 0.014 ○○○○○ 1.24 1.23718195476052
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2030  AIK80636.1  114 aa hypothetical protein 9.8e-9 ○○○○○ 1.24 1.23733049207114
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4944  AIK83470.1  277 aa PRD domain protein <1e-323 ○○○○○ 1.24 1.23746273497529
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5150  AIK83671.1  238 aa C-5 cytosine-specific DNA methylase family protein 1.1e-6 ○○○○○ 1.24 1.23897148009357
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0521  WP_000561177.1  E8X887  ybbJ  150 aa NfeD family protein 0.014 ○○○○○ 1.24 1.23928989164808
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1732  AIK80352.1  410 aa adenosylmethionine-8-amino-7-oxononanoate transaminase <1e-323 ○○○○○ 1.24 1.23962323031668
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0550  WP_000580915.1  E8X8B6  fdrA  554 aa acyl-CoA synthetase FdrA 0.0048 ○○○○○ 1.24 1.24049043719158
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1852  AIK80458.1  224 aa amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein <1e-323 ○○○○○ 1.24 1.24057598648859
Acinetobacter baumannii ATCC 17978  A1S_0484  ABO10939.2  206 aa hypothetical protein 3.1e-7 ○○○○○ 1.24 1.24146176754339
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4134  WP_001277136.1  E8XJE4  155 aa thioesterase family protein 0.00012 ○○○○○ 1.24 1.24179922506062
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0795  WP_000128327.1  E8XB00  359 aa iron ABC transporter permease 0.0045 ○○○○○ 1.24 1.24193954026341
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2143  WP_001201306.1  E8XC12  pduX  300 aa L-threonine kinase PduX 0.0092 ○○○○○ 1.24 1.242153034181
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0728  NP_233115.1  Q9KLL5  723 aa hypothetical protein 0.00031 ○○○○○ 1.24 1.24319895775433
Escherichia coli M12  CO715_03780  ATI04937.1  296 aa 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase ArnD 3.8e-7 ○○○○○ 1.24 1.24445534020892
Acinetobacter baumannii ATCC 17978  A1S_0486  ABO10941.2  170 aa thermoresistant gluconokinase 4.6e-7 ○○○○○ 1.24 1.24464027657466
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1650  CBW17745.1  A0A0H3NLR7  btuR  196 aa COB(I) alamin adenosyltransferase 0.0081 ○○○○○ 1.25 1.24652866053283
Porphyromonas gingivalis ATCC 33277  PGN_0286  WP_012457395.1  B2RHG0  107 aa DUF1661 domain-containing protein 0.00032 ○○○○○ 1.25 1.24668405334845
Porphyromonas gingivalis ATCC 33277  PGN_0061  WP_012457207.1  B2RGT5  110 aa DUF3989 domain-containing protein 0.041 ○○○○○ 1.25 1.24668405334845
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0624  NP_233013.1  Q9KLW7  tkt2  680 aa transketolase 0.027 ○○○○○ 1.25 1.24708766471866
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3344  WP_000115874.1  E8XBB9  ygiE  257 aa zinc transporter ZupT 0.0097 ○○○○○ 1.25 1.24810342795734
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0221  WP_000017171.1  E8XI10  433 aa MFS transporter 0.01 ○○○○○ 1.25 1.24968999675208
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2640  WP_000133541.1  E8XGM7  pepB  427 aa aminopeptidase PepB 0.0035 ○○○○○ 1.25 1.25013702961622
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5155  AIK83676.1  305 aa exonuclease, RdgC family protein <1e-323 ○○○○○ 1.25 1.25024718676388
Escherichia coli M12  CO715_17840  ATI07414.1  403 aa YgeY family selenium metabolism-linked hydrolase 6.5e-11 ○○○○○ 1.25 1.25071472063639
Escherichia coli M12  CO715_08215  ATI05699.1  246 aa pyruvate formate lyase-activating protein 1.5e-30 ○○○○○ 1.25 1.25092336665064
Escherichia coli M12  CO715_12790  ATI06507.1  174 aa SCP2 domain-containing protein 2.0e-35 ○○○○○ 1.25 1.25134065867914
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0374  WP_000393711.1  E8XJQ8  467 aa cytochrome ubiquinol oxidase subunit I 0.0016 ○○○○○ 1.25 1.2519945550219
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1086  AIK79709.1  197 aa bacterial regulatory, tetR family protein 3.8e-10 ○○○○○ 1.25 1.25329067352728
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5055  AIK83581.1  107 aa hypothetical protein <1e-323 ○○○○○ 1.25 1.25342047582233
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2920  WP_000744413.1  E8XK26  325 aa tripartite tricarboxylate transporter substrate binding protein 0.0012 ○○○○○ 1.25 1.25354986366692
Escherichia coli M12  CO715_13975  ATI06716.1  236 aa copper homeostasis/adhesion lipoprotein NlpE 4.2e-10 ○○○○○ 1.25 1.25384441085012
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4027  AIK82574.1  130 aa hypothetical protein <1e-323 ○○○○○ 1.26 1.25519311194116
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4424  WP_000179176.1  E8X8Z2  malK  369 aa maltose/maltodextrin ABC transporter ATP-binding protein MalK 0.0034 ○○○○○ 1.26 1.25703620931315
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4813  AIK83340.1  67 aa hypothetical protein <1e-323 ○○○○○ 1.26 1.25747795308293
Acinetobacter baumannii ATCC 17978  A1S_1753  ABO12180.2  247 aa AdeR 5.5e-7 ○○○○○ 1.26 1.25764370894777
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4184  WP_072077162.1  E8XJI8  glnL  66 aa hypothetical protein 0.0053 ○○○○○ 1.26 1.2577222536624
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1608  AIK80228.1  95 aa hypothetical protein 1.0e-15 ○○○○○ 1.26 1.25818304258469
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2692  CBW18794.1  A0A0H3NEV3  277 aa hypothetical capsid protein 0.049 ○○○○○ 1.26 1.25821930755061
Escherichia coli M12  CO715_23565  ATI08426.1  308 aa HTH-type transcriptional activator AllS 4.4e-61 ○○○○○ 1.26 1.2584346231636
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0560  NP_232950.1  Q9KM29  412 aa diguanylate cyclase 0.039 ○○○○○ 1.26 1.25912689169692
Escherichia coli M12  CO715_13745  ATI06675.1  551 aa alpha,alpha-phosphotrehalase 0.00031 ○○○○○ 1.26 1.25926920722059
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1724  WP_071525150.1  E8XKS4  yciS  73 aa hypothetical protein 0.00035 ○○○○○ 1.26 1.25940579409526
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1725  WP_000948651.1  E8XKS5  pgpB  254 aa phosphatidylglycerophosphatase B 0.00035 ○○○○○ 1.26 1.25940579409526
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1982  CBW18079.1  A0A0H3ND47  722 aa hypothetical exported protein 0.018 ○○○○○ 1.26 1.25986650881096
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2328  CBW18430.1  A0A0H3NDY4  473 aa hypothetical amino acid transporter 0.0077 ○○○○○ 1.26 1.26034065857899
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1856  WP_000457305.1  E8X8K5  yebn  206 aa manganese efflux pump MntP 0.004 ○○○○○ 1.26 1.26049287404574
Escherichia coli M12  CO715_12165  ATI06397.1  322 aa type II secretion system protein 3.4e-55 ○○○○○ 1.26 1.26072972932034
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2168  AIK80773.1  558 aa glucose inhibited division A family protein <1e-323 ○○○○○ 1.26 1.26136173113463
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4136  AIK82682.1  198 aa 5-formyltetrahydrofolate cyclo-ligase <1e-323 ○○○○○ 1.26 1.26238173841541
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1658  NP_231295.1  Q9KRI3  417 aa serine transporter 0.018 ○○○○○ 1.26 1.26266565992985
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3377  WP_000617687.1  E8XBF1  ygjR  332 aa Gfo/Idh/MocA family oxidoreductase 0.017 ○○○○○ 1.26 1.26274750851404
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0972  WP_000056911.1  E8XDD8  ycaQ  410 aa winged helix-turn-helix domain-containing protein 0.0058 ○○○○○ 1.26 1.26398367489297
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3218  WP_000218569.1  E8X9P2  141 aa DUF296 domain-containing protein 0.0097 ○○○○○ 1.26 1.26410061989463
Escherichia coli M12  CO715_16545  ATI07183.1  261 aa carnitinyl-CoA dehydratase 4.2e-20 ○○○○○ 1.26 1.26469400359106
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0924  WP_000458775.1  E8XCP5  hcp  550 aa hydroxylamine reductase 0.0069 ○○○○○ 1.26 1.26498108892486
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4058  WP_000940991.1  E8XIJ9  yieN  498 aa ATPase RavA 0.013 ○○○○○ 1.27 1.26500228890977
Escherichia coli M12  CO715_01760  ATI04567.1  281 aa carbon-phosphorus lyase complex subunit PhnJ 1.8e-61 ○○○○○ 1.27 1.26511129561956
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1354  AIK79977.1  85 aa protein involved in stress resistance and biofilm formation <1e-323 ○○○○○ 1.27 1.26565721838393
Escherichia coli M12  CO715_02125  ATI04634.1  245 aa hypothetical protein 0.034 ○○○○○ 1.27 1.26615452569081
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5070  AIK83596.1  278 aa non-heme chloroperoxidase 9.6e-11 ○○○○○ 1.27 1.26680036015991
Acinetobacter baumannii ATCC 17978  A1S_0654  ABO11103.2  102 aa regulatory protein ArsR 5.0e-6 ○○○○○ 1.27 1.26725124099936
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3814  WP_001188414.1  E8XFV7  tag  193 aa DNA-3-methyladenine glycosylase I 0.0078 ○○○○○ 1.27 1.26739114338396
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3815  WP_000619902.1  E8XFV8  yiac  146 aa N-acetyltransferase 0.0078 ○○○○○ 1.27 1.26739114338396
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4077  AIK82623.1  237 aa hypothetical protein <1e-323 ○○○○○ 1.27 1.26834237949033
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4311  WP_000813834.1  E8XL83  yijD  119 aa YijD family membrane protein 0.005 ○○○○○ 1.27 1.26857685677967
Escherichia coli M12  CO715_13695  ATI06666.1  131 aa hypothetical protein 1.3e-5 ○○○○○ 1.27 1.26907556989029
Retrieved entries 34,801–34,900 out of 36,363 total in 598.4 ms (Link to these results)