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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_05660  ATI05257.1  75 aa AlpA family phage regulatory protein 5.7e-15 ●●○○○ -1.13 -1.13118817802861
Escherichia coli M12  CO715_11085  ATI06197.1  267 aa hypothetical protein 1.7e-18 ●●○○○ -1.13 -1.13077088600011
Escherichia coli M12  CO715_20610  ATI07914.1  375 aa iron uptake system protein EfeO 2.9e-10 ●●○○○ -1.13 -1.13056223998586
Escherichia coli M12  CO715_22885  ATI08320.1  716 aa carbon starvation protein A 2.2e-8 ●●○○○ -1.13 -1.13056223998586
Escherichia coli M12  CO715_22315  ATI08225.1  67 aa LysR family transcriptional regulator 2.9e-5 ●●○○○ -1.13 -1.12972765592887
Escherichia coli M12  CO715_19475  ATI07707.1  644 aa exoribonuclease 2 4.5e-64 ●●○○○ -1.13 -1.12931036390037
Escherichia coli M12  CO715_05555  ATI05241.1  686 aa oligopeptidase B 1.9e-15 ●●○○○ -1.13 -1.12931036390037
Escherichia coli M12  CO715_19715  ATI07747.1  264 aa hypothetical protein 1.1e-24 ●●○○○ -1.13 -1.12826713382913
Escherichia coli M12  CO715_23940  ATI08491.1  252 aa DeoR/GlpR family transcriptional regulator 0.00033 ●●○○○ -1.13 -1.12784984180063
Streptococcus pyogenes M1 5448  SP5448_02490  WP_002983486.1  98 aa YlxR family protein 0.049 ●●○○○ -1.13 -1.12782427054904
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0764  NP_233150.1  Q9KLI0  185 aa MutT/nudix family protein 1.9e-5 ●●○○○ -1.13 -1.12672047902277
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2627  WP_000003211.1  E8XGL4  yfgB  388 aa bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN 0.0092 ●●○○○ -1.13 -1.12666404496772
Escherichia coli M12  CO715_20875  ATI07962.1  251 aa flagellar biosynthesis protein FlgF 5.7e-125 ●●○○○ -1.13 -1.12638931970089
Escherichia coli M12  CO715_19115  ATI07640.1  266 aa DUF218 domain-containing protein 1.8e-6 ●●○○○ -1.13 -1.12638931970089
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1575  NP_231215.1  Q9KRR1  152 aa hypothetical protein 1.1e-8 ●●○○○ -1.13 -1.12582259371569
Escherichia coli M12  CO715_00315  ATI04315.1  444 aa transcriptional regulator 0.00058 ●●○○○ -1.13 -1.12555473564389
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0117  NP_232518.1  Q9KN48  530 aa sigma-54 dependent transcriptional regulator 1.4e-6 ●●○○○ -1.13 -1.12552459566942
Escherichia coli M12  CO715_03710  ATI04926.1  402 aa deubiquitinase 5.0e-39 ●●○○○ -1.13 -1.12534608962964
Escherichia coli M12  CO715_19335  ATI07680.1  168 aa 2-Cys peroxiredoxin 6.6e-20 ●●○○○ -1.12 -1.12492879760114
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2622  WP_001177074.1  E8XGK9  yfgL  392 aa outer membrane protein assembly factor BamB 0.029 ●●○○○ -1.12 -1.12482698783251
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2411  AIK81008.1  144 aa type II secretion system protein G 0.039 ●●○○○ -1.12 -1.12478160230864
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4435  WP_000416272.1  E8X903  zur  171 aa zinc uptake transcriptional repressor Zur 0.005 ●●○○○ -1.12 -1.12399127905753
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4890  AIK83417.1  478 aa magnesium transporter 0.013 ●●○○○ -1.12 -1.12386603119773
Porphyromonas gingivalis ATCC 33277  PGN_1120  WP_004585530.1  B2RJU4  385 aa Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha <1e-323 ●●○○○ -1.12 -1.12365342636109
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2525  WP_000722926.1  E8XFN1  yfeN  253 aa outer membrane protein 0.025 ●●○○○ -1.12 -1.12360655357378
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1438  WP_001081022.1  E8XHC5  ydhO  284 aa peptidoglycan endopeptidase 2.0e-13 ●●○○○ -1.12 -1.12334122685375
Escherichia coli M12  CO715_09740  ATI05965.1  37 aa DNA-binding protein 0.0011 ●●○○○ -1.12 -1.1230509834729
Escherichia coli M12  CO715_08765  ATI05797.1  219 aa glutamine ABC transporter permease 0.025 ●●○○○ -1.12 -1.1230509834729
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3523  CBW19617.2  A0A0H3NH34  ugpB  430 aa glycerol-3-phosphate-binding periplasmic protein 0.031 ●●○○○ -1.12 -1.1228989338491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4715  AIK83249.1  111 aa BMC domain protein 0.0015 ●●○○○ -1.12 -1.1228469513278
Escherichia coli M12  CO715_21355  ATI08048.1  604 aa ABC transporter substrate-binding protein 7.9e-19 ●●○○○ -1.12 -1.12284233745865
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1509  WP_001117602.1  E8XI79  ynfe  812 aa dimethyl sulfoxide reductase subunit A 0.025 ●●○○○ -1.12 -1.12248691466746
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2945  WP_000246625.1  E8XK51  nrdE  714 aa class 1b ribonucleoside-diphosphate reductase subunit alpha 6.4e-7 ●●○○○ -1.12 -1.12230124459407
Escherichia coli M12  CO715_10340  ATI06061.1  231 aa dethiobiotin synthase 0.0079 ●●○○○ -1.12 -1.12221639941591
Escherichia coli M12  CO715_07200  ATI05522.1  285 aa spermidine/putrescine ABC transporter permease PotB 1.2e-28 ●●○○○ -1.12 -1.12179910738741
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4003  WP_000106953.1  E8XHR2  torS  911 aa TMAO reductase system sensor histidine kinase/response regulator TorS 0.025 ●●○○○ -1.12 -1.12113025636731
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4799  AIK83326.1  662 aa tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 0.00018 ●●○○○ -1.12 -1.12084607947159
Acinetobacter baumannii ATCC 17978  A1S_2781  ABO13193.2  346 aa rod shape-determining protein 1.0e-11 ●●○○○ -1.12 -1.12027842781177
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2957  AIK81542.1  123 aa plasmid stability family protein 3.6e-5 ●●○○○ -1.12 -1.11922670211382
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2041  NP_231675.1  Q9KQF7  600 aa hypothetical protein 5.0e-7 ●●○○○ -1.12 -1.11866296333714
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4490  WP_000093130.1  E8X9U5  yjdE  445 aa arginine/agmatine antiporter 0.00043 ●●○○○ -1.12 -1.11847756560634
Escherichia coli M12  CO715_10890  ATI06158.1  288 aa quinate/shikimate dehydrogenase 8.1e-16 ●●○○○ -1.12 -1.11825212514518
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0394  CBW16494.1  A0A0H3NI36  brnQ  439 aa branched chain amino acid transport system II carrier protein 0.046 ●●○○○ -1.12 -1.11810890142097
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2207  NP_231838.1  Q9KQ00  222 aa hypothetical protein 7.3e-7 ●●○○○ -1.12 -1.11700415754892
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3198  AIK81766.1  240 aa hypothetical protein <1e-323 ●●○○○ -1.12 -1.11667584602847
Escherichia coli M12  CO715_18805  ATI07585.1  386 aa bifunctional chorismate mutase/prephenate dehydratase 2.1e-66 ●●○○○ -1.12 -1.11658295703119
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1853  AIK80459.1  241 aa ABC transporter family protein 2.4e-9 ●●○○○ -1.12 -1.11638043442519
Escherichia coli M12  CO715_13155  ATI06571.1  212 aa stringent starvation protein A 3.7e-11 ●●○○○ -1.12 -1.11616566500269
Escherichia coli M12  CO715_22165  ATI08197.1  421 aa ATP-dependent RNA helicase RhlB 6.0e-58 ●●○○○ -1.11 -1.1144964968887
Escherichia coli M12  CO715_23830  ATI08472.1  50 aa protein HokE 1.3e-5 ●●○○○ -1.11 -1.1144964968887
Escherichia coli M12  CO715_06740  ATI05438.1  219 aa isomerase/hydrolase 7.7e-9 ●●○○○ -1.11 -1.11428785087445
Acinetobacter baumannii ATCC 17978  A1S_0768  ABO11208.2  295 aa putative transcriptional regulator (LysR family) 5.2e-8 ●●○○○ -1.11 -1.11420208181213
Escherichia coli M12  CO715_19730  ATI07750.1  550 aa bifunctional UDP-sugar hydrolase/5'-nucleotidase 1.7e-17 ●●○○○ -1.11 -1.11366191283171
Escherichia coli M12  CO715_19410  ATI07694.1  472 aa gamma-glutamylputrescine synthetase PuuA 3.4e-52 ●●○○○ -1.11 -1.11282732877471
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2435  AIK81032.1  178 aa hypoxanthine phosphoribosyltransferase 6.6e-5 ●●○○○ -1.11 -1.11248208979857
Escherichia coli M12  CO715_00610  ATI04368.1  232 aa autotransporter outer membrane beta-barrel domain-containing protein 7.2e-27 ●●○○○ -1.11 -1.11241003674621
Escherichia coli M12  CO715_18325  ATI07501.1  234 aa YggS family pyridoxal phosphate enzyme 3.1e-6 ●●○○○ -1.11 -1.11220139073196
Escherichia coli M12  CO715_22310  ATI08224.1  195 aa cysteine/O-acetylserine transporter 0.008 ●●○○○ -1.11 -1.11157545268922
Escherichia coli M12  CO715_14700  ATI06851.1  89 aa hypothetical protein 1.9e-5 ●●○○○ -1.11 -1.11053222261797
Escherichia coli M12  CO715_05170  ATI05174.1  222 aa amino acid ABC transporter permease 0.0003 ●●○○○ -1.11 -1.11053222261797
Porphyromonas gingivalis ATCC 33277  PGN_0533  WP_005874622.1  B2RI57  308 aa quinolinate synthase NadA <1e-323 ●●○○○ -1.11 -1.10947120268965
Acinetobacter baumannii ATCC 17978  A1S_3134  ABO13531.2  423 aa glutamate dehydrogenase (NAD(P)+) oxidoreductase protein 1.2e-11 ●●○○○ -1.11 -1.10944458396467
Escherichia coli M12  CO715_21440  ATI08064.1  416 aa NupC/NupG family nucleoside CNT transporter 1.8e-23 ●●○○○ -1.11 -1.10928034653248
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1147  NP_230792.1  Q9KSV9  422 aa iron-containing alcohol dehydrogenase 1.6e-5 ●●○○○ -1.11 -1.10914017323659
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0008  WP_000380372.1  E8XG28  mogA  196 aa molybdopterin adenylyltransferase 0.029 ●●○○○ -1.11 -1.10849564854955
Escherichia coli M12  CO715_23925  ATI08488.1  501 aa glycerol-3-phosphate dehydrogenase 0.00014 ●●○○○ -1.11 -1.10844576247548
Acinetobacter baumannii ATCC 17978  A1S_2331  ABO12753.1  480 aa putative acyl-CoA dehydrogenase 3.4e-8 ●●○○○ -1.11 -1.10791140106655
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0704  NP_233091.1  Q9KLN9  439 aa phosphoglycerate transport system transcriptional regulatory protein PgtA 4.3e-8 ●●○○○ -1.11 -1.10783473794021
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0011  CBW16112.1  A0A0H3N7A1  yaaI  134 aa conserved hypothetical protein 0.039 ●●○○○ -1.11 -1.10775758441811
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4919  AIK83445.1  44 aa hypothetical protein 0.0084 ●●○○○ -1.11 -1.10770626301782
Escherichia coli M12  CO715_19925  ATI07786.1  566 aa hypothetical protein 7.1e-12 ●●○○○ -1.11 -1.10656794834724
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2167  NP_231798.1  Q9KQ37  145 aa hypothetical protein 0.0045 ●●○○○ -1.11 -1.10598492667536
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3568  WP_001129708.1  E8XDU7  yrdD  180 aa DNA topoisomerase 8.0e-7 ●●○○○ -1.11 -1.10587618821835
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4023  WP_001738600.1  E8XHT2  int  235 aa recombinase 0.0089 ●●○○○ -1.11 -1.10575302234563
Escherichia coli M12  CO715_00165  ATI04286.1  458 aa exodeoxyribonuclease 7 large subunit 2.5e-65 ●●○○○ -1.11 -1.10531607226175
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1376  CBW17472.1  A0A0H3NCU0  slyA  146 aa Transcriptional regulator slyA. 0.032 ●●○○○ -1.11 -1.10525953124589
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3711  WP_000172397.1  E8XEP7  yhhX  345 aa oxidoreductase 5.8e-5 ●●○○○ -1.11 -1.10500176037629
Escherichia coli M12  CO715_19035  ATI07625.1  197 aa tellurite resistance methyltransferase TehB 1.4e-13 ●●○○○ -1.1 -1.10489878023325
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4247  WP_000777317.1  E8XKD2  444 aa MFS transporter 0.0057 ●●○○○ -1.1 -1.10437936583599
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0937  NP_230584.1  Q9KTG5  737 aa exopolysaccharide biosynthesis protein 2.6e-5 ●●○○○ -1.1 -1.10437223992538
Acinetobacter baumannii ATCC 17978  A1S_0762  ABO11202.2  629 aa NADH dehydrogenase I chain L 0.00011 ●●○○○ -1.1 -1.10339993009673
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2163  AIK80768.1  109 aa cytochrome o ubiquinol oxidase subunit IV 5.6e-6 ●●○○○ -1.1 -1.10263480115316
Escherichia coli M12  CO715_16080  ATI07096.1  220 aa carbonic anhydrase 1.8e-10 ●●○○○ -1.1 -1.10239502806227
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3057  WP_000912488.1  E8XL45  ygbK  420 aa 3-oxo-tetronate kinase 0.014 ●●○○○ -1.1 -1.10141218275296
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0188  WP_000245304.1  E8XHX7  yadE  409 aa polysaccharide deacetylase family protein 9.3e-6 ●●○○○ -1.1 -1.10087586203133
Escherichia coli M12  CO715_17005  ATI08844.1  116 aa protein HypA 0.0038 ●●○○○ -1.1 -1.10072585994828
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3647  CBW19740.1  A0A0H3NTL9  selB  616 aa selenocysteine-specific elongation factor 0.027 ●●○○○ -1.1 -1.10053497243611
Escherichia coli M12  CO715_06345  ATI05372.1  306 aa peptide ABC transporter permease 1.5e-25 ●●○○○ -1.1 -1.10030856791978
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2608  WP_014343875.1  E8XGJ6  78 aa hypothetical protein 9.3e-7 ●●○○○ -1.1 -1.10012886571312
Escherichia coli M12  CO715_20950  ATI07977.1  356 aa phosphate acyltransferase 2.7e-8 ●●○○○ -1.1 -1.10009992190553
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2756  WP_000219174.1  E8XIB5  srmB  444 aa ATP-dependent RNA helicase SrmB 2.3e-9 ●●○○○ -1.1 -1.09950116273773
Acinetobacter baumannii ATCC 17978  A1S_0222  ABO10697.2  430 aa putative DNA modification methylase 1.2e-6 ●●○○○ -1.1 -1.09932400310683
Escherichia coli M12  CO715_12495  ATI06451.1  220 aa DedA family protein 2.9e-49 ●●○○○ -1.1 -1.09926533784853
Escherichia coli M12  CO715_07460  ATI05565.1  546 aa paraquat-inducible protein B 9.4e-16 ●●○○○ -1.1 -1.09926533784853
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1902  NP_231536.1  Q9KQU6  dsbB  173 aa disulfide bond formation protein B 3.2e-9 ●●○○○ -1.1 -1.09906196459152
Escherichia coli M12  CO715_06980  ATI05480.1  319 aa DUF1722 domain-containing protein 1.8e-113 ●●○○○ -1.1 -1.09905669183428
Escherichia coli M12  CO715_07325  ATI05541.1  285 aa hydrogenase expression/formation protein 5.3e-6 ●●○○○ -1.1 -1.09884804582004
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3433  AIK81990.1  208 aa pyridoxamine 5'-phosphate oxidase family protein 2.6e-6 ●●○○○ -1.1 -1.09863285277341
Escherichia coli M12  CO715_05580  ATI05246.1  290 aa hypothetical protein 3.2e-7 ●●○○○ -1.1 -1.09843075379154
Escherichia coli M12  CO715_08300  ATI05714.1  234 aa leucyl/phenylalanyl-tRNA--protein transferase 4.3e-5 ●●○○○ -1.1 -1.09843075379154
Retrieved entries 3,801–3,900 out of 36,363 total in 549.5 ms (Link to these results)