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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_20200  ATI08873.1  303 aa recombination-associated protein RdgC 1.5e-25 ●●○○○ -1.06 -1.05649290492752
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3918  AIK82465.1  147 aa putative uPF0306 protein yhbP 4.0e-6 ●●○○○ -1.06 -1.05610319639839
Escherichia coli M12  CO715_09165  ATI05865.1  134 aa acyl-CoA thioester hydrolase YbgC 0.014 ●●○○○ -1.06 -1.05607561289902
Acinetobacter baumannii ATCC 17978  A1S_0764  ABO11204.2  498 aa NADH dehydrogenase I chain N 0.0011 ●●○○○ -1.06 -1.05562031384434
Escherichia coli M12  CO715_05285  ATI05193.1  266 aa trehalose-phosphatase 8.6e-8 ●●○○○ -1.05 -1.05482373681353
Escherichia coli M12  CO715_21235  ATI08027.1  220 aa heme exporter protein B 0.0067 ●●○○○ -1.05 -1.05482373681353
Acinetobacter baumannii ATCC 17978  A1S_3130  ABO13527.2  489 aa succinylglutamic semialdehyde dehydrogenase 9.6e-7 ●●○○○ -1.05 -1.05478198120431
Escherichia coli M12  CO715_05280  ATI05192.1  328 aa arabinose ABC transporter permease 4.4e-11 ●●○○○ -1.05 -1.05461509079928
Escherichia coli M12  CO715_08875  ATI05817.1  413 aa cardiolipin synthase B 5.0e-5 ●●○○○ -1.05 -1.05398915275653
Escherichia coli M12  CO715_19795  ATI07762.1  183 aa adenine phosphoribosyltransferase 9.6e-6 ●●○○○ -1.05 -1.05336321471378
Escherichia coli M12  CO715_08710  ATI05788.1  306 aa transpeptidase 2.6e-13 ●●○○○ -1.05 -1.05273727667104
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0577  WP_000703614.1  E8X930  yfdH  308 aa glycosyltransferase 5.5e-6 ●●○○○ -1.05 -1.05268648910867
Escherichia coli M12  CO715_08435  ATI05736.1  242 aa arginine ABC transporter ATP-binding protein ArtP 3.7e-18 ●●○○○ -1.05 -1.05252863065679
Escherichia coli M12  CO715_08095  ATI05675.1  615 aa L,D-transpeptidase 2.1e-41 ●●○○○ -1.05 -1.05231998464254
Escherichia coli M12  CO715_19045  ATI07627.1  326 aa hypothetical protein 7.8e-5 ●●○○○ -1.05 -1.05231998464254
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1591  NP_231231.1  Q9KRP5  252 aa short chain dehydrogenase/reductase family oxidoreductase 1.0e-6 ●●○○○ -1.05 -1.05229600517433
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3149  AIK81721.1  253 aa uridine phosphorylase <1e-323 ●●○○○ -1.05 -1.05211258488101
Escherichia coli M12  CO715_06145  ATI05335.1  530 aa autoinducer-2 kinase 8.8e-56 ●●○○○ -1.05 -1.05190269261404
Escherichia coli M12  CO715_17565  ATI07367.1  343 aa transcriptional regulator 5.1e-8 ●●○○○ -1.05 -1.05190269261404
Escherichia coli M12  CO715_20030  ATI07807.1  163 aa nucleotide-binding protein 3.1e-10 ●●○○○ -1.05 -1.05148540058554
Escherichia coli M12  CO715_02960  ATI04788.1  285 aa MurR/RpiR family transcriptional regulator 0.00036 ●●○○○ -1.05 -1.05106810855705
Escherichia coli M12  CO715_17210  ATI07302.1  121 aa 6-carboxytetrahydropterin synthase QueD 3.5e-18 ●●○○○ -1.05 -1.04981623247155
Escherichia coli M12  CO715_02685  ATI04738.1  181 aa hydrogenase 4 subunit H 5.7e-6 ●●○○○ -1.05 -1.04981623247155
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3049  WP_001005807.1  E8XL37  mutS  855 aa DNA mismatch repair protein MutS 0.001 ●●○○○ -1.05 -1.04967937955183
Escherichia coli M12  CO715_14220  ATI06760.1  176 aa RNA 2',3'-cyclic phosphodiesterase 1.9e-5 ●●○○○ -1.05 -1.0496075864573
Acinetobacter baumannii ATCC 17978  A1S_2385  ABO12804.2  775 aa putative ferric acinetobactin receptor 2.6e-7 ●●○○○ -1.05 -1.04940838439296
Escherichia coli M12  CO715_07140  ATI05511.1  416 aa isocitrate dehydrogenase (NADP(+)) 8.4e-31 ●●○○○ -1.05 -1.04939894044306
Escherichia coli M12  CO715_07665  ATI05604.1  807 aa oxygen-sensing cyclic-di-GMP phosphodiesterase 6.8e-12 ●●○○○ -1.05 -1.04939894044306
Escherichia coli M12  CO715_12500  ATI06452.1  127 aa modulator protein MzrA 3.0e-5 ●●○○○ -1.05 -1.04877300240031
Escherichia coli CFT073  c1764  AAN80230.1  A0A0H2V703  1005 aa Acriflavine resistance protein B 0.042 ●●○○○ -1.05 -1.04870416469947
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1039  AIK79662.1  251 aa phenylacetic acid catabolic family protein 1.5e-7 ●●○○○ -1.05 -1.04862613375556
Escherichia coli M12  CO715_19620  ATI07733.1  520 aa anthranilate synthase component I 1.9e-15 ●●○○○ -1.05 -1.04814706435756
Acinetobacter baumannii ATCC 17978  A1S_0528  ABO10981.1  A3M237  secB  152 aa protein exporting molecular chaperone 1.3e-8 ●●○○○ -1.05 -1.04776189351088
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0128  NP_229786.1  Q9KVL4  xerC  311 aa site-specific tyrosine recombinase XerC 9.7e-9 ●●○○○ -1.05 -1.04641080282956
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4069  AIK82616.1  37 aa hypothetical protein <1e-323 ●●○○○ -1.05 -1.04604044610017
Escherichia coli M12  CO715_17370  ATI07332.1  455 aa L-serine ammonia-lyase 3.8e-9 ●●○○○ -1.05 -1.04585195820083
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0088  WP_000066317.1  E8XGZ3  629 aa sulfatase 0.014 ●●○○○ -1.05 -1.04516426468941
Escherichia coli M12  CO715_19085  ATI07634.1  546 aa methyl-accepting chemotaxis protein 6.8e-57 ●●○○○ -1.04 -1.04480872812958
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3827  AIK82377.1  296 aa aaeAB Hydroxylated, Aromatic Carboxylic Acid Efflux Transport System Protein A <1e-323 ●●○○○ -1.04 -1.043898931173
Escherichia coli M12  CO715_17085  ATI07279.1  379 aa murein hydrolase activator NlpD 1.7e-16 ●●○○○ -1.04 -1.04355685204409
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4606  AIK83140.1  159 aa positive regulator of sigma(E), RseC/MucC familyprotein 2.5e-13 ●●○○○ -1.04 -1.04304811521491
Escherichia coli M12  CO715_01680  ATI04554.1  222 aa two-component system response regulator BasR 5.1e-33 ●●○○○ -1.04 -1.04293091400134
Escherichia coli M12  CO715_07350  ATI05546.1  372 aa hydrogenase-1 small chain 5.5e-50 ●●○○○ -1.04 -1.04272226798709
Escherichia coli M12  CO715_06300  ATI05363.1  98 aa hypothetical protein 1.2e-47 ●●○○○ -1.04 -1.04251362197284
Escherichia coli M12  CO715_21215  ATI08023.1  287 aa quinol dehydrogenase ferredoxin subunit NapH 0.00048 ●●○○○ -1.04 -1.04251362197284
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2205  AIK80810.1  320 aa pfkB carbohydrate kinase family protein 7.8e-16 ●●○○○ -1.04 -1.04212003942494
Escherichia coli M12  CO715_06580  ATI05409.1  955 aa outer membrane autotransporter barrel domain-containing protein 4.3e-122 ●●○○○ -1.04 -1.0418876839301
Escherichia coli M12  CO715_19495  ATI07711.1  249 aa DeoR family transcriptional regulator 1.2e-86 ●●○○○ -1.04 -1.0418876839301
Escherichia coli M12  CO715_08720  ATI05790.1  155 aa transcriptional regulator MntR 5.9e-9 ●●○○○ -1.04 -1.0418876839301
Escherichia coli M12  CO715_17535  ATI07362.1  229 aa DNA mismatch repair protein MutH 3.2e-21 ●●○○○ -1.04 -1.04167903791585
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1235  AIK79858.1  492 aa succinylglutamic semialdehyde dehydrogenase <1e-323 ●●○○○ -1.04 -1.04151594851957
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0558  NP_232948.1  Q9KM31  522 aa gamma-glutamyltranspeptidase 1.1e-6 ●●○○○ -1.04 -1.04097902613288
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2217  WP_000870070.1  E8XCX0  baeS  467 aa two-component system sensor histidine kinase BaeS 2.9e-6 ●●○○○ -1.04 -1.04072564800149
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0388  WP_000556518.1  E8XJS2  yaiU  978 aa autotransporter outer membrane beta-barrel domain-containing protein 2.8e-6 ●●○○○ -1.04 -1.04045893678841
Acinetobacter baumannii ATCC 17978  A1S_2609  ABO13026.2  319 aa putative lipid A biosynthesis lauroyl acyltransferase 4.3e-9 ●●○○○ -1.04 -1.04031071616002
Escherichia coli M12  CO715_14225  ATI06761.1  234 aa DNA/RNA nuclease SfsA 4.8e-17 ●●○○○ -1.04 -1.04021851581611
Escherichia coli M12  CO715_11275  ATI06233.1  183 aa NAD(P)H nitroreductase 5.0e-55 ●●○○○ -1.04 -1.04000986980186
Escherichia coli M12  CO715_19940  ATI07789.1  123 aa hypothetical protein 8.5e-13 ●●○○○ -1.04 -1.03980122378761
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1667  WP_001156208.1  E8XJY4  ydaO  311 aa tRNA 2-thiocytidine(32) synthetase TtcA 2.7e-6 ●●○○○ -1.04 -1.03958452608373
Porphyromonas gingivalis ATCC 33277  PGN_1213  WP_012458110.1  B2RK37  1063 aa DUF87 domain-containing protein 1.4e-10 ●●○○○ -1.04 -1.03944304122333
Porphyromonas gingivalis ATCC 33277  PGN_0462  WP_012457524.1  B2RHY6  407 aa HAD-IIB family hydrolase 6.7e-14 ●●○○○ -1.04 -1.03922110287192
Porphyromonas gingivalis ATCC 33277  PGN_0225  WP_012457344.1  B2RH99  328 aa glycosyltransferase <1e-323 ●●○○○ -1.04 -1.03890952458067
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3973  WP_000828740.1  E8XHN3  emrD  394 aa multidrug efflux MFS transporter EmrD 0.027 ●●○○○ -1.04 -1.03853097153378
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3465  AIK82021.1  142 aa hypothetical protein 7.0e-5 ●●○○○ -1.04 -1.03744036088528
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1052  NP_233434.1  Q9KKQ0  240 aa hypothetical protein 2.0e-8 ●●○○○ -1.04 -1.03731405595894
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4410  WP_000777266.1  E8X8X8  104 aa membrane protein 1.7e-5 ●●○○○ -1.04 -1.03682164816359
Escherichia coli M12  CO715_01495  ATI04521.1  342 aa EF-P beta-lysylation protein EpmB 7.3e-11 ●●○○○ -1.04 -1.03604559553113
Escherichia coli M12  CO715_15580  ATI07007.1  367 aa glycerol dehydrogenase 5.3e-6 ●●○○○ -1.04 -1.03541965748838
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0409  WP_000964305.1  E8XKH6  rdgC  303 aa recombination-associated protein RdgC 0.0092 ●●○○○ -1.04 -1.03526223381637
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4666  WP_000103041.1  E8XBM1  argI  334 aa ornithine carbamoyltransferase 0.035 ●●○○○ -1.04 -1.03509413112141
Acinetobacter baumannii ATCC 17978  A1S_3444  ABO13833.2  125 aa putative membrane protein 3.0e-8 ●●○○○ -1.04 -1.03507190656772
Porphyromonas gingivalis ATCC 33277  PGN_1212  WP_012458109.1  B2RK36  214 aa hypothetical protein 0.00091 ●●○○○ -1.04 -1.03503368587933
Escherichia coli M12  CO715_05775  ATI05276.1  439 aa capsid assembly protein 2.5e-14 ●●○○○ -1.03 -1.03458507343139
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4623  WP_000678386.1  E8XBH9  srfJ  447 aa lysosomal glucosyl ceramidase-like type III secretion effector SrfJ 1.1e-5 ●●○○○ -1.03 -1.03427859408818
Escherichia coli M12  CO715_17695  ATI07389.1  244 aa EscJ/YscJ/HrcJ family type III secretion inner membrane ring protein 9.2e-31 ●●○○○ -1.03 -1.03416778140289
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3869  WP_000981552.1  E8XG11  351 aa LacI family DNA-binding transcriptional regulator 4.4e-5 ●●○○○ -1.03 -1.03348700421475
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0669  NP_233058.1  Q9KLS2  431 aa sugar transporter family protein 0.00012 ●●○○○ -1.03 -1.03303344007156
Escherichia coli M12  CO715_13195  ATI06578.1  455 aa periplasmic pH-dependent serine endoprotease DegQ 6.4e-18 ●●○○○ -1.03 -1.0329159053174
Escherichia coli M12  CO715_00655  ATI04373.1  119 aa type II toxin-antitoxin system RelE/ParE family toxin 5.1e-55 ●●○○○ -1.03 -1.0312467372034
Escherichia coli CFT073  c3025  AAN81475.1  A0A0H2V9E3  yfgI  179 aa Hypothetical protein yfgI 0.032 ●●○○○ -1.03 -1.03089290875703
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3054  AIK81639.1  136 aa phosphate-starvation-inducible E family protein <1e-323 ●●○○○ -1.03 -1.03081743746938
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1962  AIK80568.1  253 aa ABC transporter family protein <1e-323 ●●○○○ -1.03 -1.03054879846423
Escherichia coli M12  CO715_07585  ATI05589.1  294 aa formate dehydrogenase subunit beta 9.5e-25 ●●○○○ -1.03 -1.03020350713216
Escherichia coli M12  CO715_13105  ATI06562.1  375 aa DUF1016 domain-containing protein 3.2e-6 ●●○○○ -1.03 -1.02978621510366
Escherichia coli M12  CO715_16935  ATI07253.1  175 aa electron transporter HydN 1.6e-5 ●●○○○ -1.03 -1.02936892307517
Escherichia coli M12  CO715_06240  ATI05354.1  167 aa fimbrial protein 3.8e-20 ●●○○○ -1.03 -1.02895163104667
Escherichia coli M12  CO715_05055  ATI05156.1  309 aa LysR family transcriptional regulator 0.029 ●●○○○ -1.03 -1.02853433901817
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1155  NP_230800.1  Q9KSV1  181 aa response regulator 3.9e-7 ●●○○○ -1.03 -1.02842725850195
Escherichia coli M12  CO715_14825  ATI06874.1  392 aa type VI secretion system tube protein Hcp 4.4e-12 ●●○○○ -1.03 -1.02832569300392
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5129  AIK83654.1  50 aa hypothetical protein 2.5e-5 ●●○○○ -1.03 -1.0279774849597
Escherichia coli M12  CO715_06685  ATI05428.1  478 aa hypothetical protein 2.3e-25 ●●○○○ -1.03 -1.02769975496117
Escherichia coli CFT073  c2036  AAN80496.1  A0A0H2V9U6  ydhJ  299 aa Hypothetical protein ydhJ 0.011 ●●○○○ -1.03 -1.02756706771692
Escherichia coli M12  CO715_03905  ATI04959.1  450 aa two-component system sensor histidine kinase EnvZ 4.3e-44 ●●○○○ -1.03 -1.02749110894693
Escherichia coli M12  CO715_06340  ATI05371.1  302 aa peptide ABC transporter permease 4.1e-21 ●●○○○ -1.03 -1.02728246293268
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4126  AIK82672.1  342 aa erythrose-4-phosphate dehydrogenase 9.6e-8 ●●○○○ -1.03 -1.02725963644926
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0078  NP_232479.1  Q9KN87  110 aa hypothetical protein 0.0021 ●●○○○ -1.03 -1.02717483141641
Escherichia coli M12  CO715_17375  ATI07333.1  251 aa flap endonuclease Xni 5.5e-9 ●●○○○ -1.03 -1.02707381691843
Porphyromonas gingivalis ATCC 33277  PGN_1340  WP_012458200.1  B2RKG4  987 aa tetratricopeptide repeat protein <1e-323 ●●○○○ -1.03 -1.0265567601522
Escherichia coli M12  CO715_13945  ATI06710.1  217 aa methionine ABC transporter 5.5e-6 ●●○○○ -1.03 -1.02644787887568
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1930  WP_000716748.1  E8X9G4  yebb  199 aa YebB family permuted papain-like enzyme 3.6e-6 ●●○○○ -1.03 -1.02637640110803
Retrieved entries 4,001–4,100 out of 36,363 total in 6.4 ms (Link to these results)