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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0888  NP_230535.1  Q9KTL4  truC  244 aa tRNA pseudouridine synthase C 0.043 ○○○○○ 0.17 0.166415394802157
Porphyromonas gingivalis ATCC 33277  PGN_1814  WP_012458552.1  B2RLT8  344 aa tRNA 2-selenouridine(34) synthase MnmH <1e-323 ○○○○○ 0.17 0.166614680173403
Porphyromonas gingivalis ATCC 33277  PGN_0138  WP_004584701.1  B2RH12  139 aa DUF3127 domain-containing protein 9.3e-9 ○○○○○ 0.17 0.166614680173403
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2663  AIK81257.1  716 aa carbon starvation CstA family protein <1e-323 ○○○○○ 0.17 0.167046737444216
Escherichia coli M12  CO715_04820  ATI05113.1  258 aa DUF2135 domain-containing protein 1.3e-6 ○○○○○ 0.17 0.16805055269905
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3466  AIK82022.1  248 aa ferredoxin-NADP reductase 0.032 ○○○○○ 0.17 0.168705063600609
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3491  AIK82047.1  218 aa DNA repair RadC family protein 3.2e-5 ○○○○○ 0.17 0.168735136278311
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3053  AIK81638.1  294 aa malG <1e-323 ○○○○○ 0.17 0.169624664861271
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4250  AIK82795.1  292 aa putative oxidoreductase, NAD(P)-binding protein <1e-323 ○○○○○ 0.17 0.169773511994657
Escherichia coli M12  CO715_19350  ATI07683.1  465 aa hypothetical protein 8.2e-7 ○○○○○ 0.17 0.169928366827289
Escherichia coli M12  CO715_08525  ATI05754.1  95 aa hypothetical protein 0.0031 ○○○○○ 0.17 0.170762950884285
Escherichia coli M12  CO715_23140  ATI08365.1  181 aa N-acetyltransferase 0.0073 ○○○○○ 0.17 0.170762950884285
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0919  NP_230566.1  Q9KTI3  184 aa serine acetyltransferase-like protein 0.0062 ○○○○○ 0.17 0.170906904647079
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2040  AIK80646.1  343 aa branched-chain amino acid transport system / permease component family protein 3.1e-9 ○○○○○ 0.17 0.17092240548001
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4385  AIK82928.1  379 aa glycerate kinase I 0.041 ○○○○○ 0.17 0.170925831642735
Escherichia coli M12  CO715_15365  ATI06971.1  344 aa rhamnose/proton symporter RhaT 0.0035 ○○○○○ 0.17 0.171388888927031
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2604  NP_232232.1  Q9KNX6  slyD  201 aa FKBP-type peptidylprolyl isomerase 0.045 ○○○○○ 0.17 0.171536908928013
Escherichia coli M12  CO715_03385  ATI04862.1  249 aa fimbrial protein 0.0013 ○○○○○ 0.17 0.17159753494128
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0116  NP_229775.1  Q9KVM5  480 aa coproporphyrinogen III oxidase 0.0014 ○○○○○ 0.17 0.171660027870199
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2810  AIK81399.1  902 aa magnesium-translocating P-type ATPase 1.6e-5 ○○○○○ 0.17 0.171705496056432
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0925  NP_230572.1  Q9KTH7  365 aa polysaccharide biosynthesis protein 0.0077 ○○○○○ 0.17 0.171705655611622
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2452  NP_232081.1  Q9KPC1  rlmD  440 aa 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD 0.00016 ○○○○○ 0.17 0.172058456947251
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4048  AIK82595.1  238 aa tonB-system energizer ExbB 7.5e-8 ○○○○○ 0.17 0.172925664766734
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4123  AIK82669.1  422 aa porin D <1e-323 ○○○○○ 0.17 0.17298262598075
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1806  NP_231441.1  Q9KR40  328 aa hypothetical protein 0.029 ○○○○○ 0.17 0.173062024921122
Escherichia coli M12  CO715_07565  ATI05585.1  366 aa phosphoporin PhoE 5.0e-6 ○○○○○ 0.17 0.173892641098018
Escherichia coli M12  CO715_18115  ATI07463.1  298 aa LysR family transcriptional regulator 2.3e-13 ○○○○○ 0.17 0.174101287112267
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1146  NP_230791.2  Q9KSW0  grx  87 aa glutaredoxin 1 0.016 ○○○○○ 0.17 0.174203253576033
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0058  NP_229717.1  Q9KVT1  184 aa carbonic anhydrase 0.00019 ○○○○○ 0.17 0.174410424218277
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2252  AIK80857.1  299 aa branched-chain amino acid transport system / permease component family protein <1e-323 ○○○○○ 0.17 0.174861601230887
Escherichia coli M12  CO715_07550  ATI05582.1  462 aa NarK family nitrate/nitrite MFS transporter 1.4e-9 ○○○○○ 0.17 0.174935871169262
Escherichia coli M12  CO715_13010  ATI06545.1  328 aa arabinose-5-phosphate isomerase KdsD 0.00018 ○○○○○ 0.17 0.174935871169262
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1277  NP_230922.1  Q9KSH9  216 aa LuxR family transcriptional regulator 0.0033 ○○○○○ 0.17 0.174983595451059
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2444  AIK81041.1  120 aa hypothetical protein <1e-323 ○○○○○ 0.18 0.175040278731776
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3150  AIK81722.1  270 aa putative dienelactone hydrolase 1.7e-9 ○○○○○ 0.18 0.17564156192827
Escherichia coli M12  CO715_05920  ATI05296.1  199 aa Ail/Lom family protein 1.5e-6 ○○○○○ 0.18 0.175979101240506
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1485  AIK80105.1  524 aa periplasmic oligopeptide-binding protein 5.4e-14 ○○○○○ 0.18 0.17607456558665
Escherichia coli M12  CO715_15685  ATI07026.1  614 aa TonB-dependent vitamin B12 receptor BtuB 3.9e-6 ○○○○○ 0.18 0.176187747254755
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1617  AIK80237.1  848 aa phage tail-collar fiber family protein <1e-323 ○○○○○ 0.18 0.176417797998679
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3533  AIK82089.1  418 aa valine-pyruvate aminotransferase 6.8e-14 ○○○○○ 0.18 0.176734680858247
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1799  NP_231434.1  Q9KR47  585 aa hypothetical protein 0.028 ○○○○○ 0.18 0.177308805563719
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3984  AIK82532.1  607 aa glycerol dehydratase large subunit <1e-323 ○○○○○ 0.18 0.178073685207082
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2459  NP_232088.1  Q9KPB4  recO  241 aa DNA repair protein RecO 0.0028 ○○○○○ 0.18 0.178175992905534
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0243  NP_232641.1  Q9KMS7  273 aa hypothetical protein 0.0014 ○○○○○ 0.18 0.178418497413788
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3851  AIK82401.1  234 aa N-acetylmannosamine-6-phosphate 2-epimerase 0.00066 ○○○○○ 0.18 0.178490279139208
Porphyromonas gingivalis ATCC 33277  PGN_0014  WP_012457171.1  B2RGN8  748 aa hypothetical protein 9.9e-8 ○○○○○ 0.18 0.178614631834425
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3424  AIK81981.1  387 aa drug resistance transporter, Bcr/CflA subfamily protein <1e-323 ○○○○○ 0.18 0.178808988322693
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4079  AIK82625.1  417 aa nupG nucleoside MFS transporter <1e-323 ○○○○○ 0.18 0.17953160202829
Porphyromonas gingivalis ATCC 33277  PGN_0793  WP_012457783.1  B2RIW7  897 aa 4-alpha-glucanotransferase 9.5e-11 ○○○○○ 0.18 0.180219519722168
Escherichia coli M12  CO715_07375  ATI05550.1  396 aa 23S rRNA (cytosine(1962)-C(5))-methyltransferase 2.8e-6 ○○○○○ 0.18 0.182029835653723
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2084  NP_231716.1  Q9KQB6  sucD  290 aa succinyl-CoA synthetase subunit alpha 0.029 ○○○○○ 0.18 0.18242743232416
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3606  AIK82161.1  423 aa PAP2 superfamily protein <1e-323 ○○○○○ 0.18 0.18260451753822
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2218  AIK80823.1  1045 aa ATP-dependent dsDNA exonuclease 8.5e-7 ○○○○○ 0.18 0.182667860870312
Escherichia coli M12  CO715_20230  ATI07844.1  63 aa hypothetical protein 3.1e-34 ○○○○○ 0.18 0.183073065724968
Escherichia coli M12  CO715_25085  ATI08670.1  305 aa hypothetical protein 0.0079 ○○○○○ 0.18 0.183073065724968
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4162  AIK82708.1  577 aa single-stranded-DNA-specific exonuclease RecJ 1.2e-8 ○○○○○ 0.18 0.184187588603468
Escherichia coli M12  CO715_08340  ATI05720.1  648 aa macrolide ABC transporter ATP-binding protein/permease MacB 0.029 ○○○○○ 0.18 0.184324941810461
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3556  AIK82112.1  311 aa pfkB carbohydrate kinase family protein <1e-323 ○○○○○ 0.19 0.185665194607961
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0760  NP_230409.1  Q9KTX0  hisS  422 aa histidyl-tRNA synthetase 5.5e-5 ○○○○○ 0.19 0.185830383410909
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1004  NP_233388.1  Q9KKU6  204 aa hypothetical protein 0.041 ○○○○○ 0.19 0.185849655691289
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3931  AIK82479.1  154 aa hypothetical protein <1e-323 ○○○○○ 0.19 0.187014073622879
Escherichia coli M12  CO715_02505  ATI04704.1  772 aa alpha-xylosidase 3.5e-9 ○○○○○ 0.19 0.187245986009945
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1224  NP_230869.1  Q9KSN2  259 aa hypothetical protein 0.0054 ○○○○○ 0.19 0.187715497248077
Escherichia coli M12  CO715_23795  ATI08465.1  415 aa miniconductance mechanosensitive channel YbdG 6.0e-10 ○○○○○ 0.19 0.187871924052691
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1744  NP_231380.1  Q9KR98  93 aa hypothetical protein 0.023 ○○○○○ 0.19 0.188499249255534
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2390  AIK80987.1  504 aa dgt 1.8e-11 ○○○○○ 0.19 0.188565081281694
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3503  AIK82059.1  359 aa glycosyltransferase 9 family protein <1e-323 ○○○○○ 0.19 0.189142548314762
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0199  NP_229856.1  Q9KVE7  611 aa hemolysin secretion ATP-binding protein 0.027 ○○○○○ 0.19 0.189543482277418
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0605  NP_230255.1  Q9KUB7  126 aa hypothetical protein 0.03 ○○○○○ 0.19 0.189685880438888
Escherichia coli M12  CO715_11955  ATI06358.1  392 aa Ni/Fe-hydrogenase b-type cytochrome subunit 9.6e-13 ○○○○○ 0.19 0.190167030209429
Escherichia coli M12  CO715_14515  ATI06816.1  93 aa PTS sugar transporter subunit IIB 1.2e-17 ○○○○○ 0.19 0.190792968252176
Escherichia coli M12  CO715_01620  ATI04544.1  239 aa two-component system response regulator DcuR 1.3e-11 ○○○○○ 0.19 0.19183619832342
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4376  AIK82919.1  445 aa putative oxidoreductase <1e-323 ○○○○○ 0.19 0.192815156239124
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3557  AIK82113.1  249 aa xylose isomerase-like TIM barrel family protein <1e-323 ○○○○○ 0.19 0.193364561185047
Escherichia coli M12  CO715_18885  ATI07599.1  801 aa type VI secretion system tip protein VgrG 9.7e-5 ○○○○○ 0.19 0.193505366437411
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2519  AIK81116.1  454 aa citrate/malate transporter 1.4e-14 ○○○○○ 0.19 0.193666741376588
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4153  AIK82699.1  242 aa helix-turn-helix domain, rpiR family protein 7.0e-14 ○○○○○ 0.19 0.193793897931333
Escherichia coli M12  CO715_06360  ATI05374.1  215 aa MarC family protein 1.9e-5 ○○○○○ 0.19 0.193922658465908
Escherichia coli M12  CO715_03475  ATI04879.1  337 aa aspartate-semialdehyde dehydrogenase 0.00017 ○○○○○ 0.19 0.193922658465908
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0037  NP_229696.1  Q9KVV2  92 aa hypothetical protein 0.02 ○○○○○ 0.19 0.194085711071125
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0776  NP_233162.1  Q9KLG8  pxpA  246 aa LamB/YcsF family protein 0.0094 ○○○○○ 0.19 0.194085836686076
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3475  AIK82031.1  416 aa voltage gated chloride channel family protein 3.2e-8 ○○○○○ 0.19 0.194281443175762
Escherichia coli M12  CO715_14335  ATI06780.1  342 aa hemin-degrading factor 6.2e-10 ○○○○○ 0.19 0.194548596508655
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3297  AIK81858.1  469 aa nitrogen regulation protein NR 3.3e-9 ○○○○○ 0.19 0.194699787204262
Escherichia coli M12  CO715_22800  ATI08305.1  262 aa hydroxamate siderophore iron reductase FhuF 0.023 ○○○○○ 0.19 0.194965888537153
Escherichia coli M12  CO715_05200  ATI05180.1  182 aa CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 6.2e-8 ○○○○○ 0.2 0.195174534551402
Escherichia coli M12  CO715_21315  ATI08041.1  586 aa ATP-dependent helicase 0.041 ○○○○○ 0.2 0.195174534551402
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0018  NP_229677.1  Q9KVX0  145 aa 16 kDa heat shock protein A 0.037 ○○○○○ 0.2 0.195185444651018
Escherichia coli M12  CO715_01585  ATI04537.1  485 aa MFS transporter 0.011 ○○○○○ 0.2 0.195591826579899
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0632  NP_230281.1  Q9KU91  487 aa D-alanyl-D-alanine carboxypeptidase/endopeptidase 0.0055 ○○○○○ 0.2 0.195797888049987
Porphyromonas gingivalis ATCC 33277  PGN_1639  WP_005874159.1  B2RLB3  109 aa cupin domain-containing protein <1e-323 ○○○○○ 0.2 0.195872204518818
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0498  NP_232889.1  Q9KM84  173 aa hypothetical protein 0.029 ○○○○○ 0.2 0.195872746542157
Escherichia coli M12  CO715_06985  ATI05481.1  174 aa hypothetical protein 3.1e-12 ○○○○○ 0.2 0.196009118608397
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2670  NP_232298.1  Q9KNR1  tpiA  265 aa triosephosphate isomerase 0.019 ○○○○○ 0.2 0.196206896633196
Escherichia coli M12  CO715_14500  ATI06813.1  89 aa HPr family phosphocarrier protein 3.1e-27 ○○○○○ 0.2 0.196426410636895
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2364  NP_231994.2  Q9KPK3  819 aa bifunctional aspartokinase I/homoserine dehydrogenase I 0.023 ○○○○○ 0.2 0.197528324439117
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0817  NP_230466.1  Q9KTS1  327 aa transposase 0.014 ○○○○○ 0.2 0.197648659562599
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0039  NP_229698.1  Q9KVV0  280 aa SpoOM-like protein 0.043 ○○○○○ 0.2 0.197838178749486
Escherichia coli M12  CO715_09620  ATI05942.1  311 aa pyrimidine-specific ribonucleoside hydrolase RihA 8.3e-8 ○○○○○ 0.2 0.197886932736637
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1208  NP_230853.1  Q9KSP8  106 aa dsDNA-mimic protein 0.026 ○○○○○ 0.2 0.197925180521094
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