Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1653  WP_000139702.1  E8XJX1  hrpA  1300 aa ATP-dependent RNA helicase HrpA 2.7e-14 ●●○○○ -1.93 -1.93298438747829
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0753  CBW16851.1  A0A0H3N9R0  galE  338 aa UDP-glucose 4-epimerase 0.00065 ●●○○○ -1.93 -1.93253166680768
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4682  WP_000453340.1  E8XBN7  idnD  343 aa L-idonate 5-dehydrogenase 1.6e-11 ●●○○○ -1.93 -1.93164969359432
Mycobacterium avium subsp. paratuberculosis K10  MAP_1450c  AAS03767.1  Q740A1  541 aa hypothetical protein 0.02 ●●○○○ -1.93 -1.93159666473779
Escherichia coli O157:H7 str. EDL933  Z5203  AAG58908.1  476 aa tryptophanase 0.028 ●●○○○ -1.93 -1.93139391822992
Escherichia coli M12  CO715_03420  ATI04869.1  361 aa chorismate synthase 0.013 ●●○○○ -1.93 -1.93113699665874
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3358  CBW19453.1  A0A0H3NGL5  fis  98 aa Fis DNA-binding protein 0.00029 ●●○○○ -1.93 -1.93102035398298
Mycobacterium avium subsp. paratuberculosis K10  MAP_1215  AAS03532.1  Q740X7  118 aa hypothetical protein 0.02 ●●○○○ -1.93 -1.93093610482993
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1406  WP_001079760.1  E8XH95  sseC  484 aa SPI-2 type III secretion system translocon protein SseC 6.5e-13 ●●○○○ -1.93 -1.93063805345494
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4689  WP_001193068.1  E8XBP3  694 aa protease Lon-related BREX system protein BrxL 9.6e-5 ●●○○○ -1.93 -1.93059925337476
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2529  NP_232157.1  Q9KP49  487 aa RNA polymerase factor sigma-54 3.2e-9 ●●○○○ -1.93 -1.92998132771228
Streptococcus pyogenes M1 5448  SP5448_06895  WP_010922049.1  312 aa ABC transporter permease 0.041 ●●○○○ -1.93 -1.92957890993508
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4192  WP_001042092.1  E8XJJ6  282 aa hypothetical protein 1.2e-10 ●●○○○ -1.93 -1.92934765503954
Escherichia coli M12  CO715_05855  ATI08741.1  67 aa phage tail protein 5.6e-23 ●●○○○ -1.93 -1.9292591825305
Mycobacterium avium subsp. paratuberculosis K10  MAP_2551  AAS04868.1  Q73WV9  180 aa hypothetical protein 0.02 ●●○○○ -1.93 -1.92915033762455
Escherichia coli M12  CO715_16570  ATI07188.1  382 aa carbamoyl-phosphate synthase small subunit 6.5e-14 ●●○○○ -1.93 -1.92905053651625
Escherichia coli M12  CO715_02995  ATI04795.1  122 aa hypothetical protein 7.1e-6 ●●○○○ -1.93 -1.92884189050201
Mycobacterium avium subsp. paratuberculosis K10  MAP_2768c  AAS05085.1  Q73W92  345 aa hypothetical protein 0.02 ●●○○○ -1.93 -1.92844739230186
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4259  AIK82805.1  331 aa periplasmic binding and sugar binding domain of LacI family protein 1.2e-9 ●●○○○ -1.93 -1.92767087049286
Escherichia coli M12  CO715_23185  ATI08372.1  210 aa protein SgcE 3.8e-11 ●●○○○ -1.93 -1.92717272238801
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3880  CBW19970.1  A0A0H3NUD0  rffD  420 aa UDP-ManNAc dehydrogenase 1.8e-5 ●●○○○ -1.93 -1.92661452535705
Escherichia coli M12  CO715_05150  ATI05170.1  239 aa RNA polymerase sigma factor FliA 7.9e-15 ●●○○○ -1.93 -1.92654678434527
Mycobacterium avium subsp. paratuberculosis K10  MAP_3995c  AAS06545.1  Q73SS8  cmaA2  299 aa CmaA2 0.02 ●●○○○ -1.93 -1.92642686512998
Escherichia coli M12  CO715_10670  ATI06119.1  215 aa ribonuclease T 5.4e-6 ●●○○○ -1.93 -1.92592084630252
Escherichia coli O157:H7 str. EDL933  Z5106  AAG58819.1  374 aa secreted protein EspD 0.028 ●●○○○ -1.93 -1.92566685032546
Mycobacterium avium subsp. paratuberculosis K10  MAP_0115  AAS02432.1  Q745B8  261 aa hypothetical protein 0.02 ●●○○○ -1.93 -1.92540465747931
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1513  WP_001066440.1  E8XI83  ynfB  113 aa DUF1283 family protein 4.5e-14 ●●○○○ -1.92 -1.92421841001131
Escherichia coli O157:H7 str. EDL933  Z1445  AAG55572.1  153 aa unknown protein encoded by bacteriophage BP-933W 0.028 ●●○○○ -1.92 -1.92319493972095
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3938  WP_000392694.1  E8XGW2  mgtC  231 aa MgtC family protein 4.5e-13 ●●○○○ -1.92 -1.92260653293289
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0159  CBW16261.1  A0A0H3N962  acnB  865 aa aconitate hydratase 2 (citrate hydro-lyase 2) 0.00033 ●●○○○ -1.92 -1.92148591784816
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1134  CBW17230.1  A0A0H3NC50  fabF  413 aa 3-oxoacyl-[acyl-carrier-protein] synthase II 0.00049 ●●○○○ -1.92 -1.92134103443946
Mycobacterium avium subsp. paratuberculosis K10  MAP_2863c  AAS05180.1  Q73VZ8  rnj  558 aa hypothetical protein 0.021 ●●○○○ -1.92 -1.92045675655358
Escherichia coli M12  CO715_13555  ATI06641.1  614 aa ATP-dependent DNA helicase RecQ 3.5e-21 ●●○○○ -1.92 -1.9202874039178
Acinetobacter baumannii ATCC 17978  A1S_2775  ABO13187.2  244 aa 3'-phosphoadenylylsulfate reductase 0.00037 ●●○○○ -1.92 -1.91943293211361
Escherichia coli M12  CO715_19625  ATI07734.1  531 aa bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD 1.1e-10 ●●○○○ -1.92 -1.91924417384656
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2678  WP_000684022.1  E8XHF1  305 aa oxidoreductase 7.2e-14 ●●○○○ -1.92 -1.91890916686509
Escherichia coli M12  CO715_07215  ATI05525.1  153 aa hypothetical protein 3.2e-8 ●●○○○ -1.92 -1.91882688181806
Escherichia coli M12  CO715_05895  ATI05292.1  232 aa phage minor tail protein L 2.4e-14 ●●○○○ -1.92 -1.91861823580381
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2409  WP_000419093.1  E8XEF5  elaC  305 aa ribonuclease BN 0.00021 ●●○○○ -1.92 -1.91753707245414
Acinetobacter baumannii ATCC 17978  A1S_2134  ABO12561.2  A3M6L7  coq7  211 aa putative ubiquinone biosynthesis protein 8.7e-5 ●●○○○ -1.92 -1.91691264878701
Escherichia coli M12  CO715_13910  ATI06706.1  206 aa peptidylprolyl isomerase 1.3e-6 ●●○○○ -1.92 -1.91674042167557
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0801  NP_233187.1  Q9KLE5  434 aa inosine-guanosine kinase 9.2e-10 ●●○○○ -1.92 -1.91627631547934
Escherichia coli O157:H7 str. EDL933  Z3203  AAG57099.1  394 aa O antigen polymerase 0.029 ●●○○○ -1.91 -1.91456726212142
Escherichia coli O157:H7 str. EDL933  Z0839  AAG55013.1  732 aa ornithine decarboxylase isozyme, inducible 0.029 ●●○○○ -1.91 -1.91360567814155
Escherichia coli M12  CO715_12440  ATI06443.1  167 aa M48 family peptidase 0.014 ●●○○○ -1.91 -1.91194156334785
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4195  WP_000084251.1  E8XJJ9  yihP  460 aa hypothetical protein 1.1e-5 ●●○○○ -1.91 -1.91100684924941
Escherichia coli M12  CO715_07995  ATI05657.1  169 aa 5-(carboxyamino)imidazole ribonucleotide mutase 2.1e-33 ●●○○○ -1.91 -1.91027239523386
Escherichia coli M12  CO715_10685  ATI06122.1  275 aa endopeptidase 7.2e-11 ●●○○○ -1.91 -1.90943781117686
Escherichia coli M12  CO715_12755  ATI06500.1  191 aa osmotically-inducible protein OsmY 8.9e-13 ●●○○○ -1.91 -1.90881187313412
Escherichia coli M12  CO715_01185  ATI04466.1  230 aa FadR family transcriptional regulator 4.7e-13 ●●○○○ -1.91 -1.90860322711987
Mycobacterium avium subsp. paratuberculosis K10  MAP_1317c  AAS03634.1  Q740N3  197 aa hypothetical protein 0.021 ●●○○○ -1.91 -1.90665091992821
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0303  WP_000932531.1  E8XIV6  rhs1  87 aa hypothetical protein 2.2e-13 ●●○○○ -1.91 -1.90565955487485
Mycobacterium avium subsp. paratuberculosis K10  MAP_2279  AAS04596.1  Q73XN0  306 aa hypothetical protein 0.021 ●●○○○ -1.91 -1.90509300868137
Escherichia coli M12  CO715_06255  ATI08746.1  65 aa Two-protein-system connector protein SafA 5.9e-11 ●●○○○ -1.9 -1.90443030683489
Acinetobacter baumannii ATCC 17978  A1S_2423  ABO12841.1  A3M7E7  rpmE  74 aa 50S ribosomal protein L31 3.2e-12 ●●○○○ -1.9 -1.90428398164109
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5060  AIK83586.1  129 aa malonate semialdehyde decarboxylase 0.0018 ●●○○○ -1.9 -1.90348634564569
Escherichia coli O157:H7 str. EDL933  Z0502  AAG54750.1  481 aa hypothetical protein 0.029 ●●○○○ -1.9 -1.90322410518314
Escherichia coli M12  CO715_08270  ATI05709.1  1368 aa DNA translocase FtsK 2.1e-6 ●●○○○ -1.9 -1.9031784307494
Escherichia coli M12  CO715_05090  ATI05162.1  348 aa hypothetical protein 3.7e-7 ●●○○○ -1.9 -1.9027611387209
Escherichia coli M12  CO715_22030  ATI08174.1  456 aa phosphomannomutase CpsG 4.4e-38 ●●○○○ -1.9 -1.90255249270665
Escherichia coli O157:H7 str. EDL933  Z3183  AAG57080.1  356 aa histidinol-phosphate aminotransferase 0.029 ●●○○○ -1.9 -1.90203738082535
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3203  AIK81772.1  495 aa threonine ammonia-lyase, biosynthetic <1e-323 ●●○○○ -1.9 -1.90184902772316
Escherichia coli M12  CO715_23260  ATI08385.1  73 aa hypothetical protein 1.6e-5 ●●○○○ -1.9 -1.90004874053566
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1550  WP_002851328.1  A0A0H3PAU5  pflA  788 aa paralyzed flagella protein PflA 0.034 ●●○○○ -1.9 -1.8993000663
Escherichia coli M12  CO715_20245  ATI07847.1  269 aa pyrroline-5-carboxylate reductase 3.9e-8 ●●○○○ -1.9 -1.89921415647867
Streptococcus pyogenes M1 5448  SP5448_06790  WP_010922103.1  186 aa hydrolase 0.037 ●●○○○ -1.9 -1.89881614199701
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4049  AIK82596.1  141 aa tonB system transport protein ExbD 2.5e-7 ●●○○○ -1.9 -1.89824830218754
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0014  NP_232415.1  Q9KNF0  726 aa 4-alpha-glucanotransferase 1.4e-9 ●●○○○ -1.9 -1.89822586225262
Escherichia coli M12  CO715_17570  ATI07368.1  420 aa diaminopimelate decarboxylase 6.6e-14 ●●○○○ -1.9 -1.89796228039317
Escherichia coli M12  CO715_05345  ATI05203.1  349 aa chemotaxis response regulator protein-glutamate methylesterase 2.1e-10 ●●○○○ -1.9 -1.89775363437893
Acinetobacter baumannii ATCC 17978  A1S_2252  ABO12675.2  195 aa putative colicin V producing membrane protein 2.0e-25 ●●○○○ -1.9 -1.89676047838192
Escherichia coli M12  CO715_17490  ATI07353.1  1122 aa exonuclease V subunit gamma 2.9e-8 ●●○○○ -1.9 -1.89671040430768
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1921  NP_231555.1  Q9KQS7  clpX  426 aa ATP-dependent protease ATP-binding subunit ClpX 3.4e-7 ●●○○○ -1.9 -1.89657752698082
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0055  CBW16156.1  A0A0G2QBP4  dcoB  433 aa oxaloacetate decarboxylase beta chain (ec 4.1.1.3) 0.00014 ●●○○○ -1.9 -1.89617926373188
Escherichia coli O157:H7 str. EDL933  Z5119  AAG58832.1  446 aa escN 0.03 ●●○○○ -1.9 -1.89589123389759
Escherichia coli M12  CO715_09660  ATI05949.1  160 aa hypothetical protein 3.2e-13 ●●○○○ -1.9 -1.89587582025069
Escherichia coli M12  CO715_06120  ATI05330.1  340 aa autoinducer 2 ABC transporter substrate-binding protein 6.7e-9 ●●○○○ -1.89 -1.89420665213669
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2308  WP_000957746.1  E8XDQ5  rtn  518 aa cyclic di-GMP phosphodiesterase 0.00018 ●●○○○ -1.89 -1.89345573264083
Escherichia coli M12  CO715_00130  ATI04281.1  206 aa ancillary SecYEG translocon subunit 2.7e-14 ●●○○○ -1.89 -1.8933720680797
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0567  WP_000754233.1  E8X921  fimD  870 aa fimbrial biogenesis outer membrane usher protein 0.00011 ●●○○○ -1.89 -1.89283321190706
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0927  WP_002853332.1  A0A0H3PGI3  250 aa amino acid ABC transporter permease 0.035 ●●○○○ -1.89 -1.89265967832
Escherichia coli M12  CO715_21650  ATI08102.1  243 aa HTH-type transcriptional regulator MlrA 6.3e-20 ●●○○○ -1.89 -1.8925374840227
Escherichia coli M12  CO715_07855  ATI05633.1  183 aa protein YmfL 4.6e-14 ●●○○○ -1.89 -1.8925374840227
Escherichia coli M12  CO715_06335  ATI05370.1  337 aa ABC transporter ATP-binding protein 5.4e-10 ●●○○○ -1.89 -1.89232883800846
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0120  NP_232521.1  Q9KN45  1181 aa IcmF-like protein 1.9e-7 ●●○○○ -1.89 -1.89191179359844
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0126  NP_229784.2  Q9KVL6  dapF  276 aa diaminopimelate epimerase 5.6e-10 ●●○○○ -1.89 -1.89174369014481
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1327  CBW17423.1  A0A0H3NAY4  ssaB  133 aa Type III secretion system effector protein, Interferes with endosomal trafficking 0.00082 ●●○○○ -1.89 -1.89145008415737
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0511  NP_232902.1  Q9KM77  706 aa anaerobic ribonucleoside triphosphate reductase 4.2e-7 ●●○○○ -1.89 -1.89124506331831
Mycobacterium avium subsp. paratuberculosis K10  MAP_2927  AAS05244.1  Q73VT4  312 aa hypothetical protein 0.022 ●●○○○ -1.89 -1.89043878071098
Escherichia coli O157:H7 str. EDL933  Z4289  AAG58075.1  165 aa hypothetical protein 0.03 ●●○○○ -1.89 -1.89024645522407
Porphyromonas gingivalis ATCC 33277  PGN_1199  WP_012458098.1  B2RK23  152 aa histidinol phosphate phosphatase <1e-323 ●●○○○ -1.89 -1.88972326226292
Escherichia coli M12  CO715_05480  ATI08734.1  310 aa zinc ABC transporter substrate-binding protein 9.3e-8 ●●○○○ -1.89 -1.88919914779472
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1424  WP_002860370.1  A0A0H3PDW4  339 aa dehydrogenase 0.035 ●●○○○ -1.89 -1.88740198497
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2066  WP_001241579.1  E8XB54  129 aa RusA family crossover junction endodeoxyribonuclease 5.9e-14 ●●○○○ -1.89 -1.88716650833864
Escherichia coli M12  CO715_22715  ATI08290.1  407 aa phosphopentomutase 2.5e-14 ●●○○○ -1.89 -1.88711268765223
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2570  AIK81167.1  426 aa threonine synthase <1e-323 ●●○○○ -1.89 -1.88698546896814
Mycobacterium avium subsp. paratuberculosis K10  MAP_1637c  AAS03954.1  Q73ZG6  479 aa hypothetical protein 0.022 ●●○○○ -1.89 -1.88696511468895
Mycobacterium avium subsp. paratuberculosis K10  MAP_2704  AAS05021.1  Q73WF6  257 aa hypothetical protein 0.022 ●●○○○ -1.89 -1.88693291345823
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4846  AIK83373.1  100 aa NADH:ubiquinone oxidoreductase, membrane subunitK 0.00043 ●●○○○ -1.89 -1.88624241373225
Escherichia coli M12  CO715_22735  ATI08294.1  287 aa YjjW family glycine radical enzyme activase 6.4e-85 ●●○○○ -1.89 -1.88586081156674
Retrieved entries 1,901–2,000 out of 36,363 total in 1807.6 ms (Link to these results)