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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4458  AIK83001.1  255 aa hydrogenase 3 and formate hydrogenlyase complex,HycG subunit 0.00038 ●●○○○ -1.63 -1.62980496457023
Escherichia coli M12  CO715_09900  ATI05994.1  137 aa proofreading thioesterase EntH 0.029 ●●○○○ -1.63 -1.62943486005489
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3955  CBW20045.1  A0A0H3NI16  typA  607 aa GTP-binding protein 0.00059 ●●○○○ -1.63 -1.62884941393853
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0436  CBW16537.1  A0A0H3N8D3  cyoB  663 aa cytochrome o ubiquinol oxidase subunit I 0.005 ●●○○○ -1.63 -1.62844289345084
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4430  WP_000002902.1  E8X8Z8  dgkA  122 aa diacylglycerol kinase 0.00093 ●●○○○ -1.63 -1.62778546099359
Acinetobacter baumannii ATCC 17978  A1S_0706  ABO11150.1  273 aa putative hydrolase 1.5e-14 ●●○○○ -1.63 -1.62707147613743
Mycobacterium avium subsp. paratuberculosis K10  MAP_2487c  AAS04804.1  Q73X23  163 aa hypothetical protein 0.035 ●●○○○ -1.63 -1.62697233671062
Mycobacterium avium subsp. paratuberculosis K10  MAP_1590  AAS03907.1  Q73ZL2  oxyR  325 aa OxyR 0.035 ●●○○○ -1.63 -1.62661020852494
Escherichia coli M12  CO715_16145  ATI07108.1  887 aa pyruvate dehydrogenase E1 component 2.9e-9 ●●○○○ -1.63 -1.62630516984116
Escherichia coli M12  CO715_11480  ATI06271.1  321 aa oxidoreductase 0.03 ●●○○○ -1.63 -1.62630516984116
Escherichia coli M12  CO715_14390  ATI06791.1  120 aa arsenical resistance operon transcriptional repressor ArsD 0.00034 ●●○○○ -1.63 -1.62547058578416
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1872  WP_000551143.1  E8X9A8  879 aa PqiB family protein 0.00018 ●●○○○ -1.63 -1.62502039987436
Escherichia coli M12  CO715_15165  ATI06936.1  236 aa hypothetical protein 8.7e-22 ●●○○○ -1.62 -1.62484464774142
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1641  CBW17736.1  A0A0H3NDF4  yciS  102 aa conserved hypothetical protein 0.013 ●●○○○ -1.62 -1.62469243484377
Escherichia coli M12  CO715_07080  ATI05499.1  122 aa lambda prophage-derived protein ea10 8.9e-56 ●●○○○ -1.62 -1.62421870969867
Escherichia coli M12  CO715_21640  ATI08100.1  243 aa osmoprotectant uptake system permease 1.3e-7 ●●○○○ -1.62 -1.62421870969867
Escherichia coli M12  CO715_16460  ATI07166.1  428 aa chaperone SurA 1.3e-12 ●●○○○ -1.62 -1.62380141767017
Escherichia coli M12  CO715_07330  ATI05542.1  132 aa hydrogenase-1 operon protein HyaE 0.0043 ●●○○○ -1.62 -1.62380141767017
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4637  WP_000435389.1  E8XBJ3  120 aa hypothetical protein 0.0011 ●●○○○ -1.62 -1.6233308945926
Acinetobacter baumannii ATCC 17978  A1S_0229  ABO10704.2  356 aa putative membrane protein 0.016 ●●○○○ -1.62 -1.62311548300798
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1685  NP_231321.1  Q9KRF7  256 aa hypothetical protein 1.3e-8 ●●○○○ -1.62 -1.62273424221975
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2509  AIK81105.1  233 aa thiamine ABC transporter, ATP-binding protein 1.5e-10 ●●○○○ -1.62 -1.62255671428573
Acinetobacter baumannii ATCC 17978  A1S_1000  ABO11432.2  302 aa sulfate adenylyltransferase subunit 2 3.4e-20 ●●○○○ -1.62 -1.62244065827732
Escherichia coli M12  CO715_17135  ATI07289.1  302 aa sulfate adenylyltransferase subunit 2 7.0e-8 ●●○○○ -1.62 -1.62234089557043
Escherichia coli M12  CO715_20540  ATI07902.1  164 aa FMN reductase 0.00021 ●●○○○ -1.62 -1.62234089557043
Mycobacterium avium subsp. paratuberculosis K10  MAP_4313  AAS06863.1  Q73RW5  374 aa hypothetical protein 0.035 ●●○○○ -1.62 -1.62221044279899
Mycobacterium avium subsp. paratuberculosis K10  MAP_1202  AAS03519.1  Q740Z0  208 aa hypothetical protein 0.035 ●●○○○ -1.62 -1.62176128530718
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2273  AIK80878.1  173 aa transposase family protein 1.4e-6 ●●○○○ -1.62 -1.62050095250413
Mycobacterium avium subsp. paratuberculosis K10  MAP_0027  AAS02344.1  Q744S8  632 aa hypothetical protein 0.035 ●●○○○ -1.62 -1.61974595618958
Escherichia coli M12  CO715_05695  ATI05264.1  81 aa hypothetical protein 4.1e-10 ●●○○○ -1.62 -1.61941985137094
Escherichia coli M12  CO715_02245  ATI04657.1  309 aa homoserine O-succinyltransferase 0.03 ●●○○○ -1.62 -1.61941985137094
Escherichia coli M12  CO715_21660  ATI08104.1  239 aa DNA-binding response regulator 0.00012 ●●○○○ -1.62 -1.6192112053567
Escherichia coli M12  CO715_02665  ATI04734.1  282 aa formate transporter FocA 2.2e-7 ●●○○○ -1.62 -1.61858526731395
Escherichia coli M12  CO715_09910  ATI05996.1  285 aa isochorismatase 9.0e-11 ●●○○○ -1.62 -1.61816797528545
Escherichia coli M12  CO715_20625  ATI07917.1  354 aa phosphate starvation protein PhoH 0.00022 ●●○○○ -1.62 -1.61816797528545
Mycobacterium avium subsp. paratuberculosis K10  MAP_3579c  AAS06129.1  Q73TY9  183 aa hypothetical protein 0.035 ●●○○○ -1.62 -1.61804350947368
Escherichia coli M12  CO715_05125  ATI05166.1  121 aa flagellar protein FliT 0.0017 ●●○○○ -1.62 -1.61733339122846
Streptococcus pyogenes M1 5448  SP5448_05830  WP_010922236.1  553 aa ribonuclease J 0.0033 ●●○○○ -1.62 -1.61714454806402
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2273  WP_000920081.1  E8XDM1  sanA  239 aa outer membrane permeability protein SanA 0.0014 ●●○○○ -1.62 -1.61669147767776
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1464  WP_000915668.1  E8XI38  rsxC  735 aa electron transport complex subunit RsxC 0.0019 ●●○○○ -1.62 -1.61630024310328
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0314  WP_001535430.1  E8XIW7  safB  245 aa pili assembly chaperone PapD 0.0002 ●●○○○ -1.62 -1.61604768477433
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3842  WP_000794981.1  E8XFY4  310 aa DUF4862 family protein 6.4e-19 ●●○○○ -1.62 -1.61593659764274
Escherichia coli M12  CO715_11670  ATI06304.1  433 aa inorganic triphosphatase 0.00024 ●●○○○ -1.61 -1.61462099304322
Streptococcus pyogenes M1 5448  SP5448_07765  WP_010921943.1  726 aa class 1b ribonucleoside-diphosphate reductase subunit alpha 0.049 ●●○○○ -1.61 -1.61426053856982
Escherichia coli M12  CO715_22085  ATI08182.1  279 aa transcriptional regulator 0.0049 ●●○○○ -1.61 -1.61399505500047
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0824  WP_000042502.1  E8XBR2  uvrB  673 aa excinuclease ABC subunit B 0.0018 ●●○○○ -1.61 -1.61343621721602
Escherichia coli M12  CO715_11590  ATI06291.1  269 aa 23S rRNA (guanine(745)-N(1))-methyltransferase 1.8e-16 ●●○○○ -1.61 -1.61316047094348
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2746  NP_232372.1  Q9KNJ2  glnAv  469 aa glutamine synthetase 5.2e-8 ●●○○○ -1.61 -1.61309873151243
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3842  AIK82392.1  236 aa ATP:dephospho-CoA triphosphoribosyl transferase family protein 1.9e-11 ●●○○○ -1.61 -1.61158067454457
Escherichia coli O157:H7 str. EDL933  Z0318  AAG54580.1  196 aa DNA invertase from prophage CP-933H 0.049 ●●○○○ -1.61 -1.6114307333465
Escherichia coli O157:H7 str. EDL933  Z1481  AAG55602.1  153 aa unknown protein encoded by bacteriophage BP-933W 0.049 ●●○○○ -1.61 -1.6114271639328
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0459  WP_000971352.1  E8XKM6  cyoE  296 aa protoheme IX farnesyltransferase 5.8e-10 ●●○○○ -1.61 -1.61126696276193
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0677  NP_233065.1  Q9KLR5  napD  113 aa nitrate reductase assembly protein NapD 5.7e-7 ●●○○○ -1.61 -1.61082326572831
Escherichia coli M12  CO715_01655  ATI04550.1  302 aa melibiose operon regulatory protein 1.2e-20 ●●○○○ -1.61 -1.61044807275824
Escherichia coli O157:H7 str. EDL933  Z2914  AAG56852.1  233 aa hypothetical protein 0.049 ●●○○○ -1.61 -1.60995479153531
Escherichia coli M12  CO715_16170  ATI07112.1  183 aa 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.031 ●●○○○ -1.61 -1.6098221347155
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3018  CBW19117.1  A0A0H3NFS0  recJ  577 aa single-stranded DNA-specific exonuclease 0.0013 ●●○○○ -1.61 -1.60967732088001
Escherichia coli M12  CO715_08625  ATI05772.1  303 aa glutathione ABC transporter permease GsiD 6.9e-9 ●●○○○ -1.61 -1.60857025863
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3419  CBW19514.1  A0A0H3NGT1  yheO  244 aa conserved hypothetical protein 0.0039 ●●○○○ -1.61 -1.60801087696002
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4442  AIK82985.1  423 aa PTS system, lactose/cellobiose IIC component family protein 0.0088 ●●○○○ -1.61 -1.60792535105998
Escherichia coli M12  CO715_19630  ATI08869.1  452 aa bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 2.9e-9 ●●○○○ -1.61 -1.60710973653026
Mycobacterium avium subsp. paratuberculosis K10  MAP_4307  AAS06857.1  Q73RX1  355 aa hypothetical protein 0.036 ●●○○○ -1.61 -1.60666185014864
Escherichia coli M12  CO715_08090  ATI08766.1  182 aa hypothetical protein 2.7e-6 ●●○○○ -1.61 -1.60648379848752
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1557  WP_000199411.1  E8XIZ3  502 aa hypothetical protein 2.4e-10 ●●○○○ -1.61 -1.60630340821177
Mycobacterium avium subsp. paratuberculosis K10  MAP_2302  AAS04619.1  Q73XK7  395 aa hypothetical protein 0.036 ●●○○○ -1.61 -1.60625198821678
Escherichia coli O157:H7 str. EDL933  Z3206  AAG57102.1  331 aa putative UDP-galactose 4-epimerase 0.049 ●●○○○ -1.61 -1.60599267181735
Mycobacterium avium subsp. paratuberculosis K10  MAP_0987  AAS03304.1  Q741V0  mfd  1221 aa Mfd 0.036 ●●○○○ -1.6 -1.60484782908571
Escherichia coli M12  CO715_07905  ATI05641.1  120 aa hypothetical protein 6.9e-16 ●●○○○ -1.6 -1.60481463037352
Mycobacterium avium subsp. paratuberculosis K10  MAP_0664c  AAS02981.1  Q73XK7  395 aa hypothetical protein 0.036 ●●○○○ -1.6 -1.60468740362703
Escherichia coli M12  CO715_19850  ATI07773.1  72 aa hemolysin expression-modulating protein Hha 0.0018 ●●○○○ -1.6 -1.60439733834503
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4672  AIK83206.1  73 aa addiction module antidote protein, HigA family 5.2e-6 ●●○○○ -1.6 -1.60368542594075
Escherichia coli M12  CO715_17195  ATI07299.1  244 aa phosphoadenosine phosphosulfate reductase 8.3e-9 ●●○○○ -1.6 -1.60356275428803
Escherichia coli M12  CO715_01550  ATI04531.1  191 aa transcriptional regulator 0.00017 ●●○○○ -1.6 -1.60356275428803
Escherichia coli CFT073  c2486  AAN80945.1  A0A0H2VAU5  236 aa Hypothetical protein 0.0084 ●●○○○ -1.6 -1.60296681616611
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2341  WP_001554888.1  E8XDT6  48 aa hypothetical protein 1.1e-10 ●●○○○ -1.6 -1.60208764608931
Escherichia coli M12  CO715_19965  ATI07794.1  207 aa ATP-dependent Clp protease proteolytic subunit 0.0022 ●●○○○ -1.6 -1.60126764813129
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3550  WP_001145331.1  E8XD93  699 aa bifunctional diguanylate cyclase/phosphodiesterase 2.7e-8 ●●○○○ -1.6 -1.60117525582172
Escherichia coli M12  CO715_05495  ATI05230.1  480 aa pyruvate kinase 1.9e-55 ●●○○○ -1.6 -1.6008503561028
Acinetobacter baumannii ATCC 17978  A1S_2180  ABO12607.2  516 aa hypothetical protein 3.9e-15 ●●○○○ -1.6 -1.60082619510011
Escherichia coli O157:H7 str. EDL933  Z1546  AAG55661.1  182 aa putative fatty acyl chain dehydrase 0.05 ●●○○○ -1.6 -1.60044375027221
Escherichia coli M12  CO715_17165  ATI07294.1  351 aa type I-E CRISPR-associated protein Cas7/Cse4/CasC 2.2e-34 ●●○○○ -1.6 -1.6000157720458
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1656  WP_000760345.1  E8XJX4  ydbL  107 aa DUF1318 domain-containing protein 0.0086 ●●○○○ -1.6 -1.59962092452701
Escherichia coli M12  CO715_09610  ATI05940.1  224 aa amino acid ABC transporter permease 8.5e-18 ●●○○○ -1.6 -1.5995984800173
Escherichia coli M12  CO715_16480  ATI07170.1  280 aa bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 3.1e-6 ●●○○○ -1.6 -1.5995984800173
Escherichia coli M12  CO715_02370  ATI04679.1  265 aa lipopolysaccharide core heptose(I) kinase RfaP 2.7e-18 ●●○○○ -1.6 -1.59938983400305
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2404  AIK81001.1  185 aa putative general secretion pathway protein B <1e-323 ●●○○○ -1.6 -1.59931518776291
Mycobacterium avium subsp. paratuberculosis K10  MAP_0856c  AAS03173.1  Q742H9  575 aa hypothetical protein 0.036 ●●○○○ -1.6 -1.59865295858709
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3339  CBW19435.1  A0A0H3NIB4  yhcS  309 aa probable LysR-family transcriptional regulator 0.015 ●●○○○ -1.6 -1.59841839539257
Mycobacterium avium subsp. paratuberculosis K10  MAP_3082c  AAS05630.1  Q73VD2  254 aa hypothetical protein 0.036 ●●○○○ -1.6 -1.59837908197637
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4284  AIK82829.1  231 aa DNA mismatch repair endonuclease MutH <1e-323 ●●○○○ -1.6 -1.59812057727736
Escherichia coli M12  CO715_05755  ATI05274.1  192 aa phage tail protein 6.3e-5 ●●○○○ -1.6 -1.59751201987481
Acinetobacter baumannii ATCC 17978  A1S_0500  ABO10953.2  258 aa type 4 fimbrial biogenesis protein 3.4e-9 ●●○○○ -1.6 -1.59745747999682
Escherichia coli M12  CO715_20975  ATI07982.1  413 aa beta-ketoacyl-[acyl-carrier-protein] synthase II 0.00063 ●●○○○ -1.6 -1.59709472784632
Escherichia coli O157:H7 str. EDL933  Z4365  AAG58148.1  236 aa putative enzyme 0.05 ●●○○○ -1.6 -1.59687263229549
Escherichia coli M12  CO715_11175  ATI06214.1  492 aa N-succinylglutamate 5-semialdehyde dehydrogenase 4.8e-8 ●●○○○ -1.6 -1.59646878980357
Escherichia coli M12  CO715_15915  ATI07065.1  89 aa twin-arginine translocase subunit TatA 3.3e-5 ●●○○○ -1.59 -1.59479962168958
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3594  AIK82149.1  61 aa putative antibiotic biosynthesis monooxygenase 8.4e-11 ●●○○○ -1.59 -1.59228442614906
Mycobacterium avium subsp. paratuberculosis K10  MAP_1812  AAS04129.1  Q73YZ1  cobI  496 aa CobI 0.037 ●●○○○ -1.59 -1.59165221821147
Mycobacterium avium subsp. paratuberculosis K10  MAP_4092c  AAS06642.1  Q73SI1  619 aa hypothetical protein 0.037 ●●○○○ -1.59 -1.59122275428732
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2914  AIK81500.1  120 aa fumarate reductase membrane protein <1e-323 ●●○○○ -1.59 -1.59096408796701
Retrieved entries 2,501–2,600 out of 36,363 total in 839 ms (Link to these results)