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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio parahaemolyticus RIMD 2210633  VPA_0769  BAC62112.1  Q87I37  150 aa conserved hypothetical protein 0.0053 ●●●●○ -3.01 -3.00667825456131
Vibrio parahaemolyticus RIMD 2210633  VP_2057  BAC60320.1  Q87N19  plsX  341 aa fatty acid/phospholipid synthesis protein PlsX 0.0039 ●●●○○ -3 -2.99971008579772
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3917  WP_001068438.1  E8XGU3  spoU  229 aa tRNA (guanosine(18)-2'-O)-methyltransferase TrmH 1.2e-7 ●●●○○ -3 -2.99909257421267
Vibrio parahaemolyticus RIMD 2210633  VP_2514  BAC60777.1  Q87LU4  222 aa putative carbonic anhydrase 0.0039 ●●●○○ -3 -2.99690111631798
Mycobacterium avium subsp. paratuberculosis K10  MAP_1861c  AAS04178.1  Q73YU4  299 aa hypothetical protein 0.0015 ●●●○○ -3 -2.99521145677569
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1051  WP_001220671.1  E8XE16  ycbW  180 aa cell division protein ZapC 2.0e-23 ●●●○○ -2.99 -2.99080679979911
Vibrio parahaemolyticus RIMD 2210633  VPA_1340  BAC62683.1  Q87GH6  82 aa hypothetical protein 0.0056 ●●●○○ -2.99 -2.98927468194362
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2425  WP_000062993.1  E8XEH1  nuoA  147 aa NADH-quinone oxidoreductase subunit NuoA 2.0e-23 ●●●○○ -2.99 -2.98687597891374
Vibrio parahaemolyticus RIMD 2210633  VP_2571  BAC60834.1  Q87LP0  era  320 aa GTP-binding protein Era 0.004 ●●●○○ -2.98 -2.98414721573931
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3791  AIK82346.1  272 aa dehydroshikimate reductase <1e-323 ●●●○○ -2.98 -2.98352935873419
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0820  WP_000090729.1  E8XBQ8  bioB  346 aa biotin synthase 1.1e-7 ●●●○○ -2.98 -2.98290701020749
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3088  AIK81668.1  431 aa phosphoribosylamine--glycine ligase <1e-323 ●●●○○ -2.98 -2.98249609046259
Acinetobacter baumannii ATCC 17978  A1S_0419  ABO10874.1  169 aa hypothetical protein 1.3e-51 ●●●○○ -2.98 -2.97990407676851
Acinetobacter baumannii ATCC 17978  A1S_1930  ABO12357.2  368 aa cell division protein 3.4e-36 ●●●○○ -2.98 -2.97811463401141
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1495  NP_231136.1  Q9KRY8  238 aa hypothetical protein 4.4e-10 ●●●○○ -2.98 -2.97680573399661
Acinetobacter baumannii ATCC 17978  A1S_1908  ABO12335.2  351 aa 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase 9.6e-22 ●●●○○ -2.98 -2.97676130590156
Vibrio parahaemolyticus RIMD 2210633  VP_2898  BAC61161.1  Q87KS8  purD  429 aa phosphoribosylamine-glycine ligase 0.0042 ●●●○○ -2.97 -2.97432113808409
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3046  AIK81631.1  165 aa chorismate lyase <1e-323 ●●●○○ -2.97 -2.97297784271425
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3143  AIK81715.1  178 aa twin arginine-targeting protein translocase TatB 2.7e-10 ●●●○○ -2.97 -2.97189006724269
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0487  NP_230141.1  Q9KUM8  glmS  610 aa glucosamine--fructose-6-phosphate aminotransferase 6.7e-10 ●●●○○ -2.97 -2.9704419657895
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0337  WP_001285275.1  E8XJM4  proB  367 aa glutamate 5-kinase 1.1e-7 ●●●○○ -2.97 -2.96980398154874
Mycobacterium avium subsp. paratuberculosis K10  MAP_4294  AAS06844.1  Q73RY4  fadD1  546 aa FadD1_2 0.0016 ●●●○○ -2.97 -2.96980154820058
Acinetobacter baumannii ATCC 17978  A1S_2355  ABO12774.2  194 aa anthranilate synthase component II 2.9e-28 ●●●○○ -2.97 -2.96747460787639
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0239  NP_229896.1  Q9KVA7  590 aa hypothetical protein 3.5e-5 ●●●○○ -2.97 -2.96569320623185
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3307  WP_000665657.1  E8XAK7  134 aa hypothetical protein 3.8e-16 ●●●○○ -2.96 -2.96493746666693
Vibrio parahaemolyticus RIMD 2210633  VP_2293  BAC60556.1  Q87MG2  rnhA  154 aa ribonuclease HI 0.0043 ●●●○○ -2.96 -2.96485759055321
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2316  WP_000578121.1  E8XDR3  yejH  586 aa DEAD/DEAH box helicase 4.3e-9 ●●●○○ -2.96 -2.96463335856206
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0196  WP_000899412.1  E8XHY5  sfsA  234 aa DNA/RNA nuclease SfsA 9.8e-23 ●●●○○ -2.96 -2.96398647625535
Haemophilus influenzae Rd KW20  HI_0464  NP_438625.1  P44725  rpiA  219 aa ribose-5-phosphate isomerase A 0.0042 ●●●○○ -2.96 -2.96261632158149
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0244  NP_229901.1  Q9KVA5  367 aa perosamine synthase 1.1e-14 ●●●○○ -2.96 -2.96126840168355
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5039  AIK83565.1  258 aa imidazole glycerol phosphate synthase, HisF subunit 3.5e-14 ●●●○○ -2.96 -2.96054213125548
Serratia marcescens Strain UMH9  BVG96_07845  ASL97531.1  392 aa mannose-6-phosphate isomerase 0.0082 ●●●○○ -2.96 -2.96045020512213
Vibrio parahaemolyticus RIMD 2210633  VP_2388  BAC60651.1  Q87M70  519 aa aerobic glycerol-3-phosphate dehydrogenase 0.0043 ●●●○○ -2.96 -2.96044379947717
Vibrio parahaemolyticus RIMD 2210633  VP_0799  BAC59062.1  Q87RJ5  zipA  316 aa cell division protein ZipA 0.0044 ●●●○○ -2.96 -2.95879920159225
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0329  WP_002859851.1  A0A0H3PBD0  bioA  427 aa adenosylmethionine--8-amino-7-oxononanoate transaminase 0.0026 ●●●○○ -2.96 -2.9579880712
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4523  WP_000069440.1  E8X9X7  aspA  478 aa aspartate ammonia-lyase 2.8e-7 ●●●○○ -2.96 -2.95687171239907
Acinetobacter baumannii ATCC 17978  A1S_3386  ABO13775.1  386 aa phosphoserine phosphatase 1.1e-17 ●●●○○ -2.95 -2.95269484450715
Acinetobacter baumannii ATCC 17978  A1S_0454  ABO10909.2  134 aa putative biopolymer transport protein (ExbD) 2.5e-12 ●●●○○ -2.95 -2.94924141835739
Acinetobacter baumannii ATCC 17978  A1S_1520  ABO11947.1  257 aa transketolase 1.6e-9 ●●●○○ -2.95 -2.94669749485358
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2045  NP_231679.1  Q9KQF3  194 aa superoxide dismutase 4.9e-12 ●●●○○ -2.95 -2.94640550071322
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4082  WP_001127434.1  E8XIL5  ilvD  616 aa dihydroxy-acid dehydratase 8.1e-8 ●●●○○ -2.95 -2.94635992554813
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2286  CBW18388.1  A0A0H3NDP5  nuoM  509 aa NADH dehydrogenase I chain M 2.5e-7 ●●●○○ -2.94 -2.94415056519801
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1266  WP_001738208.1  E8XFJ1  197 aa LuxR family transcriptional regulator 3.1e-5 ●●●○○ -2.94 -2.94203000766339
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4460  CBW20549.1  A0A0H3NJ72  100 aa hypothetical protein 4.0e-7 ●●●○○ -2.94 -2.94190520341578
Streptococcus pyogenes M1 5448  SP5448_02090  WP_010922593.1  410 aa beta-ketoacyl-[acyl-carrier-protein] synthase II 0.0027 ●●●○○ -2.94 -2.94186624239731
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3436  CBW19531.1  A0A0H3NIH3  pabA  187 aa para-aminobenzoate synthase, glutamine amidotransferase component II 5.8e-9 ●●●○○ -2.94 -2.93895566051272
Acinetobacter baumannii ATCC 17978  A1S_2360  ABO12779.2  A3M785  trpC  268 aa indole-3-glycerol phosphate synthase (IGPS) 2.3e-29 ●●●○○ -2.94 -2.9387482268937
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3062  WP_000863168.1  E8XL50  475 aa UbiD family decarboxylase 6.9e-9 ●●●○○ -2.94 -2.9381977090899
Haemophilus influenzae Rd KW20  HI_1617  NP_439759.1  P44425  aspC  396 aa aromatic amino acid aminotransferase 0.0045 ●●●○○ -2.93 -2.93493616232242
Vibrio parahaemolyticus RIMD 2210633  VP_1818  BAC60081.1  Q87NQ0  52 aa hypothetical protein 0.0047 ●●●○○ -2.93 -2.93268987305634
Acinetobacter baumannii ATCC 17978  A1S_0876  ABO11308.2  1010 aa putative cell division protein (FstK) 9.0e-24 ●●●○○ -2.93 -2.93259228153706
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2285  CBW18387.1  A0A0H3NFA5  nuoN  485 aa NADH dehydrogenase I chain N 9.5e-9 ●●●○○ -2.93 -2.92983370236172
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1301  NP_230946.1  Q9KSF5  417 aa serine transporter 2.0e-13 ●●●○○ -2.93 -2.9287004525718
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1645  CBW17740.1  A0A0H3NLR3  cysB  324 aa cys regulon transcriptional activator 1.4e-8 ●●●○○ -2.93 -2.92819971229692
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0165  NP_232565.1  Q9KN01  710 aa diguanylate cyclase 2.0e-11 ●●●○○ -2.93 -2.92675478840423
Vibrio parahaemolyticus RIMD 2210633  VPA_1315  BAC62658.1  Q87GK1  66 aa hypothetical protein 0.0068 ●●●○○ -2.93 -2.92668295455514
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2226  NP_231857.1  Q9KPY6  purM  346 aa phosphoribosylaminoimidazole synthetase 1.5e-10 ●●●○○ -2.93 -2.925375885636
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3438  WP_077905150.1  E8XC97  deaD  646 aa DEAD/DEAH family ATP-dependent RNA helicase 1.7e-6 ●●●○○ -2.92 -2.92168813995557
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4268  WP_000136809.1  E8XKF3  glpK  502 aa glycerol kinase GlpK 7.5e-5 ●●●○○ -2.92 -2.92124688135182
Vibrio parahaemolyticus RIMD 2210633  VP_1011  BAC59274.1  Q87QY7  741 aa isocitrate dehydrogenase 0.0049 ●●●○○ -2.92 -2.91802683597962
Mycobacterium avium subsp. paratuberculosis K10  MAP_3853  AAS06403.1  Q73T66  clpB  848 aa ClpB 0.0019 ●●●○○ -2.92 -2.91783192308892
Serratia marcescens Strain UMH9  BVG96_04545  ASL96915.1  379 aa hypothetical protein 0.00011 ●●●○○ -2.91 -2.91265465367239
Acinetobacter baumannii ATCC 17978  A1S_0784  ABO11224.2  A3M2T0  dcd  189 aa deoxycytidine triphosphate deaminase 4.0e-13 ●●●○○ -2.91 -2.91232634987753
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3041  WP_000381610.1  E8XL29  149 aa membrane protein 5.2e-34 ●●●○○ -2.91 -2.90962455710439
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0896  CBW16992.1  A0A0H3N9M1  trxB  322 aa thioredoxin reductase 1.1e-8 ●●●○○ -2.91 -2.90931518172408
Escherichia coli CFT073  c2392  AAN80851.1  A0A0H2VAK2  406 aa Putative P4-family integrase 0.036 ●●●○○ -2.91 -2.90909801547975
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0404  WP_002857514.1  A1VYA1  pyrF  226 aa orotidine-5'-phosphate decarboxylase 0.003 ●●●○○ -2.91 -2.9084959878
Acinetobacter baumannii ATCC 17978  A1S_1573  ABO12000.2  100 aa integration host factor beta subunit 1.5e-26 ●●●○○ -2.91 -2.90841784829268
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2504  CBW18605.1  A0A0H3NEC0  nifU  128 aa NifU-like protein 2.5e-9 ●●●○○ -2.91 -2.90799946563644
Vibrio parahaemolyticus RIMD 2210633  VP_0236  BAC58499.1  Q87T34  388 aa nucleotide sugar dehydrogenase 0.0051 ●●●○○ -2.9 -2.90493761212062
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1797  AIK80410.1  238 aa succinate dehydrogenase iron-sulfur protein 6.1e-5 ●●●○○ -2.9 -2.90377684964005
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3700  WP_000724553.1  E8XEN6  251 aa IclR family transcriptional regulator 2.2e-7 ●●●○○ -2.9 -2.90300353587496
Streptococcus pyogenes M1 5448  SP5448_01615  WP_001182060.1  259 aa uridine phosphorylase 0.0014 ●●●○○ -2.9 -2.90245144597666
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2954  WP_000645139.1  E8XK60  456 aa glycoporin 4.1e-23 ●●●○○ -2.9 -2.90138516268868
Streptococcus pyogenes M1 5448  SP5448_05530  WP_010922277.1  72 aa helix-turn-helix transcriptional regulator 0.0087 ●●●○○ -2.9 -2.90052877298053
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2588  AIK81185.1  323 aa phosphoserine phosphatase SerB 1.7e-5 ●●●○○ -2.9 -2.89752393328699
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0118  CBW16221.1  A0A0H3NH80  fruR  334 aa fructose repressor 7.7e-10 ●●●○○ -2.9 -2.89657000629199
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1034  WP_000725267.1  E8XDJ7  165 aa Ail/OmpX 6.7e-5 ●●●○○ -2.9 -2.89605160938168
Vibrio parahaemolyticus RIMD 2210633  VP_0337  BAC58600.1  Q87ST5  pdxA  332 aa pyridoxal phosphate biosynthetic protein PdxA 0.0053 ●●●○○ -2.89 -2.89476718140736
Haemophilus influenzae Rd KW20  HI_0066  NP_438239.1  P44493  amiB  432 aa N-acetylmuramoyl-L-alanine amidase 0.0051 ●●●○○ -2.89 -2.89219319321079
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3687  AIK82242.1  191 aa iron-sulfur cluster scaffold protein 0.031 ●●●○○ -2.89 -2.89053404464674
Streptococcus pyogenes M1 5448  SP5448_00580  WP_010921794.1  418 aa tyrosine--tRNA ligase 0.0092 ●●●○○ -2.89 -2.88899273500375
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4840  AIK83367.1  166 aa nuoE 0.0039 ●●●○○ -2.89 -2.88769557297034
Acinetobacter baumannii ATCC 17978  A1S_1988  ABO12415.1  122 aa putative intracellular sulfur oxidation protein (DsrE-like) 3.6e-8 ●●●○○ -2.89 -2.88725583222091
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1827  CBW17921.1  A0A0H3NDW8  znuB  261 aa high-affinity zinc uptake system membrane protein 6.9e-8 ●●●○○ -2.89 -2.88538053833188
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1634  WP_001081943.1  E8XJV2  mdoD  551 aa glucan biosynthesis protein D 5.7e-23 ●●●○○ -2.89 -2.88533341725911
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1003  NP_230649.1  Q9KTA0  163 aa bacteriocin production protein 5.2e-12 ●●●○○ -2.88 -2.88387413068333
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4571  WP_000547737.1  E8XAP9  yjfL  132 aa DUF350 domain-containing protein 2.2e-7 ●●●○○ -2.88 -2.88072191291038
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3797  WP_001150163.1  E8XFE1  yhjV  432 aa transporter 2.2e-7 ●●●○○ -2.88 -2.88072191291038
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0263  NP_229919.1  Q9KV93  184 aa galactosyl-transferase 4.7e-17 ●●●○○ -2.88 -2.87953552772892
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2294  CBW18396.1  A0A0H3NNY3  nuoE  166 aa NADH dehydrogenase I chain E 9.2e-7 ●●●○○ -2.88 -2.87833224341267
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4260  WP_000774147.1  E8XKE5  yneB  291 aa 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase 9.1e-8 ●●●○○ -2.88 -2.87527324207023
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1986  WP_000218080.1  E8XA97  fliZ  183 aa flagella biosynthesis regulatory protein FliZ 2.5e-7 ●●●○○ -2.87 -2.87489143409659
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2688  WP_000790154.1  E8XHG1  lepA  599 aa elongation factor 4 2.0e-7 ●●●○○ -2.87 -2.8740469634436
Acinetobacter baumannii ATCC 17978  A1S_2376  ABO12795.1  89 aa putative ABC transporter 2.1e-17 ●●●○○ -2.87 -2.87283503156776
Acinetobacter baumannii ATCC 17978  A1S_2189  ABO12616.1  428 aa phosphoribosylamine--glycine ligase 1.0e-8 ●●●○○ -2.87 -2.87235480463594
Haemophilus influenzae Rd KW20  HI_0769  NP_438928.1  P44871  ftsE  218 aa cell division ATP-binding protein 0.0055 ●●●○○ -2.87 -2.86979065401554
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0485  NP_230139.1  Q9KUN0  470 aa pyruvate kinase 1.8e-11 ●●●○○ -2.87 -2.8691801881839
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2402  WP_001255561.1  E8XEE8  menC  320 aa o-succinylbenzoate synthase 1.9e-6 ●●●○○ -2.87 -2.86831726076759
Acinetobacter baumannii ATCC 17978  A1S_1547  ABO11974.1  169 aa organic solvent tolerance protein precursor 1.1e-14 ●●●○○ -2.87 -2.86765133587807
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