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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_11170  ATI06213.1  447 aa succinylarginine dihydrolase 0.0043 ○○○○○ 0.07 0.0743684923013109
Escherichia coli M12  CO715_13995  ATI08815.1  84 aa Rho-binding antiterminator 0.014 ○○○○○ 0.07 0.0743684923013109
Escherichia coli M12  CO715_03160  ATI04822.1  285 aa AraC family transcriptional regulator 0.022 ○○○○○ 0.07 0.0743684923013109
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3263  AIK81824.1  278 aa cupin domain protein <1e-323 ○○○○○ 0.07 0.0743761237288959
Porphyromonas gingivalis ATCC 33277  PGN_0008  WP_012457165.1  B2RGN2  clpC  859 aa ATP-dependent Clp protease ATP-binding subunit 0.0017 ○○○○○ 0.07 0.0743787928851679
Escherichia coli M12  CO715_14610  ATI06834.1  117 aa hydroxymyristoyl-ACP dehydratase 0.044 ○○○○○ 0.07 0.0745771383155599
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1833  NP_231467.1  Q9KR14  nadA  353 aa quinolinate synthetase 0.00064 ○○○○○ 0.07 0.0749450986735423
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0384  NP_230038.1  Q9KUX4  cysJ  614 aa sulfite reductase (NADPH) flavoprotein subunit alpha 0.005 ○○○○○ 0.08 0.0751761882249614
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1701  AIK80321.1  330 aa transketolase, pyrimidine binding domain protein <1e-323 ○○○○○ 0.08 0.0761659868032281
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4347  AIK82890.1  352 aa membrane-bound lytic murein transglycosylase A <1e-323 ○○○○○ 0.08 0.076173365652653
Escherichia coli M12  CO715_22950  ATI08332.1  255 aa hypothetical protein 0.00026 ○○○○○ 0.08 0.0764549524437996
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4708  AIK83242.1  1037 aa acrD <1e-323 ○○○○○ 0.08 0.0764865625592026
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1398  NP_231041.1  Q9KS62  124 aa chemotaxis protein CheY 0.022 ○○○○○ 0.08 0.0765153513725964
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4635  AIK83169.1  278 aa hypothetical protein 9.7e-8 ○○○○○ 0.08 0.0765654782205426
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2301  NP_231932.1  Q9KPR5  226 aa transcriptional activator 0.0021 ○○○○○ 0.08 0.0767080566454339
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0853  NP_233239.1  Q9KL93  247 aa hypothetical protein 0.0062 ○○○○○ 0.08 0.0772831583631376
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0957  NP_230604.1  Q9KTE5  156 aa hypothetical protein 0.00023 ○○○○○ 0.08 0.077317335130066
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3837  AIK82387.1  299 aa L-tartrate dehydratase, &alpha subunit 3.7e-14 ○○○○○ 0.08 0.0774113393870514
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0002  NP_062586.1  Q9KVY6  mioC  144 aa flavodoxin 0.031 ○○○○○ 0.08 0.0775634773799251
Escherichia coli M12  CO715_11920  ATI06352.1  346 aa L-glyceraldehyde 3-phosphate reductase 1.5e-5 ○○○○○ 0.08 0.0779154745435415
Escherichia coli M12  CO715_13820  ATI06689.1  577 aa autotransporter assembly complex protein TamA 4.3e-13 ○○○○○ 0.08 0.0783327665720393
Escherichia coli M12  CO715_12135  ATI06391.1  497 aa type II secretion system protein GspE 1.2e-9 ○○○○○ 0.08 0.0789587046147859
Escherichia coli M12  CO715_12615  ATI06474.1  179 aa hypothetical protein 9.7e-6 ○○○○○ 0.08 0.0789587046147859
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3857  AIK82407.1  354 aa mannonate dehydratase <1e-323 ○○○○○ 0.08 0.0792485857567205
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1708  AIK80328.1  331 aa efflux transporter, RND family, MFP subunit 0.047 ○○○○○ 0.08 0.0793672845506257
Escherichia coli M12  CO715_22115  ATI08187.1  87 aa acetolactate synthase isozyme 2 small subunit 3.6e-7 ○○○○○ 0.08 0.0806278727287768
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0838  NP_230486.1  P0C6D6  tcpN  276 aa TCP pilus virulence regulatory protein 0.025 ○○○○○ 0.08 0.0808715182500104
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2212  AIK80817.1  457 aa amino acid permease family protein <1e-323 ○○○○○ 0.08 0.0812578664315145
Porphyromonas gingivalis ATCC 33277  PGN_0424  WP_012457496.1  B2RHU8  129 aa HIT family protein 4.4e-10 ○○○○○ 0.08 0.0814808535353669
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1028  NP_233412.1  Q56652  lamB  416 aa maltoporin 0.0065 ○○○○○ 0.08 0.0820960466627021
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1766  AIK80386.1  347 aa galactose mutarotase <1e-323 ○○○○○ 0.08 0.082136705117664
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0712  NP_233099.1  Q9KLN1  206 aa pyrazinamidase/nicotinamidase 0.031 ○○○○○ 0.08 0.0828540304379364
Escherichia coli M12  CO715_18415  ATI07519.1  711 aa ornithine decarboxylase 8.7e-5 ○○○○○ 0.08 0.0835489169282608
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4727  AIK83261.1  453 aa ethanolamine ammonia-lyase, putative regulatory subunit <1e-323 ○○○○○ 0.08 0.0835495573628747
Escherichia coli M12  CO715_13430  ATI08808.1  372 aa oxidoreductase 2.0e-14 ○○○○○ 0.08 0.0843835009852563
Escherichia coli M12  CO715_21205  ATI08886.1  239 aa periplasmic nitrate reductase subunit alpha 5.1e-9 ○○○○○ 0.08 0.0843835009852563
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1999  AIK80605.1  383 aa oxidoreductase, NAD-binding Rossmann fold family protein 1.1e-16 ○○○○○ 0.08 0.0844729246304344
Escherichia coli M12  CO715_00440  ATI04335.1  220 aa 3-keto-L-gulonate-6-phosphate decarboxylase 0.001 ○○○○○ 0.08 0.0845921469995051
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0273  NP_229929.1  Q9KV83  hupA  90 aa DNA-binding protein HU 0.00028 ○○○○○ 0.09 0.0850262000727858
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2020  AIK80626.1  258 aa lysine-arginine-ornithine-binding periplasmic family protein 1.2e-8 ○○○○○ 0.09 0.0852121989198547
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1433  NP_231076.1  Q9KS28  315 aa universal stress protein UspE 0.019 ○○○○○ 0.09 0.0852936379431458
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2282  NP_231913.1  Q9KPT0  362 aa hypothetical protein 0.05 ○○○○○ 0.09 0.0853386737264366
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1002  AIK79625.1  402 aa putative inner membrane protein 1.8e-12 ○○○○○ 0.09 0.0855094820866056
Escherichia coli M12  CO715_08980  ATI05838.1  350 aa 4-oxalomesaconate tautomerase 2.8e-9 ○○○○○ 0.09 0.0856353770707495
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3443  AIK82000.1  232 aa putative cytoplasmic protein 3.2e-8 ○○○○○ 0.09 0.0857113544216052
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3059  AIK81644.1  152 aa acetyltransferase family protein 0.013 ○○○○○ 0.09 0.0864208773662737
Porphyromonas gingivalis ATCC 33277  PGN_0872  WP_012457841.1  B2RJ46  152 aa histidinol-phosphate aminotransferase <1e-323 ○○○○○ 0.09 0.0865894137962273
Porphyromonas gingivalis ATCC 33277  PGN_0688  WP_012457701.1  B2RIL2  194 aa DUF3109 family protein 5.8e-10 ○○○○○ 0.09 0.0865894137962273
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2586  AIK81183.1  410 aa nicotinamide-nucleotide adenylyltransferase 3.6e-5 ○○○○○ 0.09 0.086622938142138
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3910  AIK82458.1  414 aa mtr tryptophan ArAAP transporter <1e-323 ○○○○○ 0.09 0.0871592042413046
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2788  AIK81377.1  501 aa methylmalonate-semialdehyde dehydrogenase <1e-323 ○○○○○ 0.09 0.0874131582132089
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2725  AIK81315.1  212 aa HNH endonuclease family protein 1.0e-7 ○○○○○ 0.09 0.0880585785033011
Escherichia coli M12  CO715_01110  ATI04454.1  207 aa ribosomal RNA small subunit methyltransferase G 0.0012 ○○○○○ 0.09 0.0883477752559847
Escherichia coli M12  CO715_12000  ATI06366.1  230 aa ATP-binding protein 2.0e-19 ○○○○○ 0.09 0.0887650672844823
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0238  NP_229895.1  Q9KVA8  188 aa hexapaptide repeat-containing transferase 0.0028 ○○○○○ 0.09 0.0891825694256412
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2438  NP_232067.1  Q9KPD4  glnE  948 aa [glutamate--ammonia-ligase] adenylyltransferase 0.0028 ○○○○○ 0.09 0.0894892998388408
Escherichia coli M12  CO715_01990  ATI04610.1  397 aa aromatic amino acid transaminase 3.8e-5 ○○○○○ 0.09 0.0895996513414778
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4790  AIK83317.1  714 aa fatty oxidation complex, alpha subunit FadJ 0.0011 ○○○○○ 0.09 0.0896769461748099
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2742  NP_232368.1  Q9KNJ6  297 aa ribonuclease BN 0.00062 ○○○○○ 0.09 0.0898515236597629
Porphyromonas gingivalis ATCC 33277  PGN_0011  WP_012457168.1  B2RGN5  256 aa 2-phosphosulfolactate phosphatase 3.4e-7 ○○○○○ 0.09 0.0904354802418289
Porphyromonas gingivalis ATCC 33277  PGN_1924  WP_012458611.1  B2RM48  cas2  96 aa CRISPR-associated endonuclease Cas2 9.3e-7 ○○○○○ 0.09 0.0904354802418289
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3026  AIK81611.1  941 aa excinuclease ABC subunit A <1e-323 ○○○○○ 0.09 0.0905325324019164
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2536  NP_232164.1  Q9KP43  193 aa hypothetical protein 2.6e-6 ○○○○○ 0.09 0.090588161336478
Porphyromonas gingivalis ATCC 33277  PGN_0811  WP_012457795.1  B2RIY5  872 aa carboxypeptidase-like regulatory domain-containing protein 4.0e-6 ○○○○○ 0.09 0.0907858817304432
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4188  AIK82733.1  507 aa bacterial extracellular solute-binding, 5 Middlefamily protein <1e-323 ○○○○○ 0.09 0.0912658257555913
Escherichia coli M12  CO715_03955  ATI04968.1  259 aa DNA utilization protein HofM 6.8e-15 ○○○○○ 0.09 0.0916861114839664
Escherichia coli M12  CO715_23815  ATI08469.1  372 aa glutamate--cysteine ligase 4.6e-6 ○○○○○ 0.09 0.0916861114839664
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1440  AIK80061.1  236 aa pyrimidine utilization protein B 4.4e-15 ○○○○○ 0.09 0.0922656498992678
Escherichia coli M12  CO715_18600  ATI07549.1  400 aa DUF3883 domain-containing protein 0.0044 ○○○○○ 0.09 0.0923120495267131
Escherichia coli M12  CO715_20315  ATI07861.1  207 aa hydrogen peroxide resistance inhibitor IprA 3.7e-10 ○○○○○ 0.09 0.0933552795979573
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2241  AIK80846.1  572 aa acyltransferase family protein <1e-323 ○○○○○ 0.09 0.0934941851216996
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4070  AIK82617.1  131 aa fimbrial family protein 0.019 ○○○○○ 0.09 0.0939798600757961
Escherichia coli M12  CO715_16175  ATI07113.1  297 aa carboxylating nicotinate-nucleotide diphosphorylase 0.0027 ○○○○○ 0.09 0.0939812176407039
Escherichia coli M12  CO715_17270  ATI07314.1  200 aa LemA family protein 8.0e-21 ○○○○○ 0.09 0.0941898636549528
Porphyromonas gingivalis ATCC 33277  PGN_1123  WP_012458044.1  B2RJU7  399 aa hypothetical protein 2.6e-15 ○○○○○ 0.09 0.0942968919333165
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1500  AIK80120.1  169 aa SOS cell division inhibitor 1.2e-9 ○○○○○ 0.09 0.0945868327186917
Escherichia coli M12  CO715_03280  ATI04844.1  354 aa P-loop NTPase 2.6e-22 ○○○○○ 0.1 0.0952330937261971
Escherichia coli M12  CO715_17310  ATI07322.1  433 aa 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD 0.00023 ○○○○○ 0.1 0.0952330937261971
Escherichia coli M12  CO715_12645  ATI06478.1  444 aa MFS transporter 5.2e-7 ○○○○○ 0.1 0.0954417397404459
Escherichia coli M12  CO715_17275  ATI07315.1  307 aa hypothetical protein 2.1e-5 ○○○○○ 0.1 0.0956503857546948
Escherichia coli M12  CO715_20500  ATI07894.1  306 aa curved DNA-binding protein 0.014 ○○○○○ 0.1 0.0960676777831925
Escherichia coli M12  CO715_05915  ATI05295.1  1158 aa host specificity protein J 3.7e-31 ○○○○○ 0.1 0.0973195538686857
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4624  AIK83158.1  396 aa oxidoreductase NAD-binding domain protein 0.0035 ○○○○○ 0.1 0.097688011453615
Escherichia coli M12  CO715_19695  ATI07744.1  451 aa transporter 3.1e-9 ○○○○○ 0.1 0.0977368458971834
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1140  NP_230785.2  Q9F855  rluE  241 aa 23S rRNA pseudouridine synthase E 0.014 ○○○○○ 0.1 0.0977733124108782
Escherichia coli M12  CO715_00485  ATI04343.1  157 aa electron transporter 1.4e-5 ○○○○○ 0.1 0.0979454919114322
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3153  AIK81725.1  266 aa sugar phosphatase <1e-323 ○○○○○ 0.1 0.0984773123421161
Escherichia coli M12  CO715_10885  ATI06157.1  421 aa MFS transporter 2.3e-38 ○○○○○ 0.1 0.0985714299541788
Escherichia coli M12  CO715_08940  ATI05830.1  384 aa 8-amino-7-oxononanoate synthase 4.2e-5 ○○○○○ 0.1 0.0987800759684277
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1857  NP_231491.1  Q9KQZ0  187 aa primosomal replication protein N`` 0.003 ○○○○○ 0.1 0.0988816277016314
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1854  NP_231488.1  Q9KQZ3  368 aa porin 3.2e-6 ○○○○○ 0.1 0.0988961451675709
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4544  AIK83082.1  506 aa amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein 0.018 ○○○○○ 0.1 0.0990024172552607
Escherichia coli M12  CO715_20735  ATI08880.1  511 aa glucan biosynthesis protein G 2.7e-7 ○○○○○ 0.1 0.0991973679969254
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1998  NP_231632.1  Q9KQK0  msrB  147 aa methionine sulfoxide reductase B 0.006 ○○○○○ 0.1 0.100111905548244
Escherichia coli M12  CO715_01465  ATI04515.1  377 aa BlaEC family class C beta-lactamase 3.4e-5 ○○○○○ 0.1 0.101075182125165
Escherichia coli M12  CO715_09480  ATI05922.1  468 aa chitoporin 2.8e-8 ○○○○○ 0.1 0.101283828139414
Escherichia coli M12  CO715_05940  ATI08743.1  97 aa hypothetical protein 1.7e-6 ○○○○○ 0.1 0.101283828139414
Escherichia coli M12  CO715_09895  ATI05993.1  701 aa carbon starvation protein 0.00055 ○○○○○ 0.1 0.101283828139414
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0618  NP_230267.1  Q9KUA5  341 aa peptide ABC transporter permease 0.0037 ○○○○○ 0.1 0.10131750197836
Escherichia coli M12  CO715_19820  ATI07767.1  1120 aa mechanosensitive channel MscK 0.00012 ○○○○○ 0.1 0.101492474153663
Retrieved entries 31,901–32,000 out of 36,363 total in 7 ms (Link to these results)