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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3461  AIK82017.1  254 aa CDP-diacylglycerol pyrophosphatase 3.5e-6 ●○○○○ -0.64 -0.635160528362659
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3817  AIK82367.1  646 aa EAL domain protein <1e-323 ●○○○○ -0.63 -0.634884448373982
Acinetobacter baumannii ATCC 17978  A1S_0944  ABO11376.2  266 aa putative transcriptional regulator (PcaU-like) 4.2e-5 ●○○○○ -0.63 -0.634498236126662
Porphyromonas gingivalis ATCC 33277  PGN_0129  WP_080504436.1  B2RH03  40 aa DNA methylase <1e-323 ●○○○○ -0.63 -0.634256456660259
Porphyromonas gingivalis ATCC 33277  PGN_0129  WP_012457268.1  B2RH03  197 aa DUF3575 domain-containing protein <1e-323 ●○○○○ -0.63 -0.634256456660259
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2600  AIK81197.1  529 aa peptide chain release factor 3 1.3e-9 ●○○○○ -0.63 -0.634087937037661
Escherichia coli M12  CO715_06960  ATI05476.1  153 aa lysis protein 2.7e-6 ●○○○○ -0.63 -0.633776080059324
Porphyromonas gingivalis ATCC 33277  PGN_0565  WP_039416960.1  B2RI89  256 aa peroxide stress protein YaaA 0.029 ●○○○○ -0.63 -0.632283952961434
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3595  AIK82150.1  667 aa asmA family protein <1e-323 ●○○○○ -0.63 -0.632104217508536
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2954  AIK81538.1  252 aa integral membrane, YjbE family protein <1e-323 ●○○○○ -0.63 -0.631352002847178
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4623  AIK83157.1  112 aa regulatory protein P-II for glutamine synthetase 1.6e-5 ●○○○○ -0.63 -0.630783204552317
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2905  AIK81491.1  243 aa artI 0.0085 ●○○○○ -0.63 -0.630587477368165
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0858  NP_230505.1  Q9KTP3  184 aa type IV pilin 4.3e-8 ●○○○○ -0.63 -0.629715609602594
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1523  WP_000106265.1  E8XI92  dcp  680 aa peptidyl-dipeptidase Dcp 0.0026 ●○○○○ -0.63 -0.629471309211933
Porphyromonas gingivalis ATCC 33277  PGN_0826  WP_012457806.1  B2RJ00  449 aa dihydrolipoyl dehydrogenase <1e-323 ●○○○○ -0.63 -0.62927303041867
Escherichia coli M12  CO715_13940  ATI06709.1  343 aa methionine import ATP-binding protein MetN 3.0e-15 ●○○○○ -0.63 -0.629185867745849
Escherichia coli M12  CO715_08045  ATI05667.1  433 aa uracil/xanthine transporter 8.8e-6 ●○○○○ -0.63 -0.629185867745849
Porphyromonas gingivalis ATCC 33277  PGN_0231  WP_012457350.1  B2RHA5  394 aa delta-aminolevulinic acid dehydratase <1e-323 ●○○○○ -0.63 -0.629088626380369
Porphyromonas gingivalis ATCC 33277  PGN_2076  WP_010956523.1  B2RMJ9  94 aa DUF1661 domain-containing protein <1e-323 ●○○○○ -0.63 -0.629005335618899
Escherichia coli M12  CO715_23190  ATI08373.1  260 aa transcriptional regulator 1.2e-7 ●○○○○ -0.63 -0.628559929703103
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0568  NP_230219.1  Q9KUF3  zapE  367 aa hypothetical protein 0.00025 ●○○○○ -0.63 -0.627956172717942
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3211  WP_001112716.1  E8X9N5  argP  83 aa hypothetical protein 4.4e-5 ●○○○○ -0.63 -0.627720342513464
Acinetobacter baumannii ATCC 17978  A1S_1643  ABO12070.2  430 aa putative acyl-CoA dehydrogenase 0.0049 ●○○○○ -0.63 -0.627642655428814
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0465  WP_000098481.1  E8XKN2  ampG  491 aa muropeptide MFS transporter AmpG 0.015 ●○○○○ -0.63 -0.627557103200879
Escherichia coli M12  CO715_00890  ATI04414.1  357 aa DNA replication and repair protein RecF 2.5e-20 ●○○○○ -0.63 -0.627099407603361
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0587  NP_230237.1  Q9KUD5  548 aa sulfate permease family protein 0.00065 ●○○○○ -0.63 -0.626881620460444
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2141  AIK80746.1  590 aa ABC transporter family protein 2.1e-11 ●○○○○ -0.63 -0.625930108461974
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1688  AIK80308.1  167 aa stationary phase nucleoid protein that sequesters iron and protects DNA from damage 8.1e-8 ●○○○○ -0.63 -0.625271752463222
Porphyromonas gingivalis ATCC 33277  PGN_0064  WP_004332888.1  B2RGT8  traI  203 aa DUF4141 domain-containing protein <1e-323 ●○○○○ -0.63 -0.625261758327095
Porphyromonas gingivalis ATCC 33277  PGN_0710  WP_012457717.1  B2RIN4  535 aa indolepyruvate ferredoxin oxidoreductase <1e-323 ●○○○○ -0.62 -0.624861507736597
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3741  AIK82296.1  72 aa slyX family protein 1.0e-15 ●○○○○ -0.62 -0.624790610840092
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4839  AIK83366.1  598 aa nuoC 0.00051 ●○○○○ -0.62 -0.624498321891453
Escherichia coli M12  CO715_17510  ATI07357.1  156 aa prepilin-type cleavage/methylation domain-containing protein 0.00039 ●○○○○ -0.62 -0.624387009418126
Acinetobacter baumannii ATCC 17978  A1S_0444  ABO10899.2  177 aa hypothetical protein 0.00019 ●○○○○ -0.62 -0.62413027320949
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1457  NP_231100.1  P01555  ctxA  258 aa cholera enterotoxin subunit A 0.046 ●○○○○ -0.62 -0.622241175972803
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2626  AIK81220.1  336 aa putative glucosamine-fructose-6-phosphate aminotransferase <1e-323 ●○○○○ -0.62 -0.621959372123584
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3846  AIK82396.1  375 aa putative ATP-dependent endonuclease <1e-323 ●○○○○ -0.62 -0.621770935975149
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2672  AIK81266.1  412 aa sugar (and other) transporter family protein <1e-323 ●○○○○ -0.62 -0.621029170964647
Porphyromonas gingivalis ATCC 33277  PGN_1892  WP_012458593.1  B2RM16  755 aa hypothetical protein 0.019 ●○○○○ -0.62 -0.620975861903413
Escherichia coli M12  CO715_20595  ATI07912.1  447 aa hypothetical protein 1.3e-5 ●○○○○ -0.62 -0.620840027175895
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3816  AIK82366.1  63 aa hypothetical protein 1.1e-8 ●○○○○ -0.62 -0.620706583420177
Escherichia coli M12  CO715_19905  ATI07782.1  593 aa multidrug resistance-like ATP-binding protein MdlB 8.7e-36 ●○○○○ -0.62 -0.620422735147397
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0682  NP_233070.1  Q9KLR0  208 aa transcriptional regulator UhpA 3.4e-7 ●○○○○ -0.62 -0.619689802717618
Escherichia coli M12  CO715_16025  ATI07085.1  264 aa 3-methyl-2-oxobutanoate hydroxymethyltransferase 2.0e-6 ●○○○○ -0.62 -0.619379505076153
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1390  WP_000269830.1  E8XH79  ttrB  250 aa tetrathionate reductase subunit TtrB 0.0034 ●○○○○ -0.62 -0.619239094922492
Acinetobacter baumannii ATCC 17978  A1S_2717  ABO13130.2  463 aa dihydrolipoamide dehydrogenase 0.015 ●○○○○ -0.62 -0.618724766733821
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3397  WP_000108129.1  E8XC60  tdcC  443 aa threonine/serine transporter TdcC 0.0049 ●○○○○ -0.62 -0.618172164902552
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0020  WP_000155792.1  E8XG40  998 aa chitinase 0.007 ●○○○○ -0.62 -0.618089961017198
Porphyromonas gingivalis ATCC 33277  PGN_0671  WP_012457687.1  B2RIJ5  pdxJ  238 aa pyridoxine 5'-phosphate synthase 0.039 ●○○○○ -0.62 -0.618019763929255
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1765  AIK80385.1  382 aa galactokinase 7.3e-5 ●○○○○ -0.62 -0.617094505931921
Escherichia coli M12  CO715_01750  ATI04565.1  194 aa phosphonate C-P lyase system protein PhnH 1.9e-7 ●○○○○ -0.62 -0.616458460876669
Acinetobacter baumannii ATCC 17978  A1S_2966  ABO13369.2  457 aa UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 0.0013 ●○○○○ -0.62 -0.616106710456303
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3550  AIK82106.1  70 aa cspA transcriptional activator 6.5e-7 ●○○○○ -0.62 -0.616001705850267
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1463  WP_000231891.1  E8XI37  rsxD  352 aa electron transport complex subunit RsxD 7.8e-5 ●○○○○ -0.62 -0.615784560938211
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4209  AIK82754.1  319 aa putative oxidoreductase, NAD(P)-binding putativeNAD(P)H-dependent xylose reductase <1e-323 ●○○○○ -0.62 -0.615489409253949
Acinetobacter baumannii ATCC 17978  A1S_2892  ABO13298.2  691 aa putative TonB-dependent receptor protein 6.1e-5 ●○○○○ -0.61 -0.614961642586108
Porphyromonas gingivalis ATCC 33277  PGN_1983  WP_012458662.1  B2RMA6  303 aa ion transporter 0.0004 ●○○○○ -0.61 -0.614493100188765
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1590  AIK80210.1  171 aa putative lipoprotein 5.5e-7 ●○○○○ -0.61 -0.61390419762002
Porphyromonas gingivalis ATCC 33277  PGN_1536  WP_012458354.1  B2RL10  346 aa hypothetical protein <1e-323 ●○○○○ -0.61 -0.613798310402954
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2944  AIK81529.1  87 aa hypothetical protein 0.0052 ●○○○○ -0.61 -0.613787318349313
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4602  WP_000689229.1  E8XAT0  68 aa DUF1107 domain-containing protein 0.012 ●○○○○ -0.61 -0.613551483224042
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3622  AIK82177.1  167 aa P-coumaric acid decarboxylase <1e-323 ●○○○○ -0.61 -0.612178922403568
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1178  NP_230823.1  Q9KSS8  206 aa hypothetical protein 0.0021 ●○○○○ -0.61 -0.611900721662381
Porphyromonas gingivalis ATCC 33277  PGN_0345  WP_004583890.1  B2RHL9  284 aa hypothetical protein <1e-323 ●○○○○ -0.61 -0.611395934846989
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3576  AIK82131.1  703 aa cellulose synthase catalytic subunit (UDP-forming) <1e-323 ●○○○○ -0.61 -0.611145562864855
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2544  AIK81141.1  594 aa oxaloacetate decarboxylase alpha subunit 7.7e-5 ●○○○○ -0.61 -0.611070033397821
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0725  WP_000997487.1  E8XA56  kdpD  894 aa two-component system sensor histidine kinase KdbD 0.0027 ●○○○○ -0.61 -0.611067109115697
Acinetobacter baumannii ATCC 17978  A1S_0913  ABO11345.2  368 aa hypothetical protein 0.00018 ●○○○○ -0.61 -0.610952688587481
Escherichia coli M12  CO715_20400  ATI07877.1  316 aa acetaldehyde dehydrogenase 0.00069 ●○○○○ -0.61 -0.610407726463452
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3939  AIK82487.1  130 aa doxX family protein 0.00018 ●○○○○ -0.61 -0.60959701518564
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1653  AIK80273.1  197 aa PAP2 superfamily protein 0.0028 ●○○○○ -0.61 -0.609406191053165
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1487  WP_000014056.1  E8XI58  pntB  462 aa Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.0067 ●○○○○ -0.61 -0.609272136726279
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3282  AIK81843.1  804 aa formate dehydrogenase, alpha subunit <1e-323 ●○○○○ -0.61 -0.609173140914126
Acinetobacter baumannii ATCC 17978  A1S_0265  ABO10740.1  72 aa hypothetical protein 0.00048 ●○○○○ -0.61 -0.609087064960145
Porphyromonas gingivalis ATCC 33277  PGN_0237  WP_012457355.1  B2RHB1  206 aa YigZ family protein <1e-323 ●○○○○ -0.61 -0.608653456892976
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4514  WP_000842434.1  E8X9W9  phoN  250 aa non-specific acid phosphatase 0.0031 ●○○○○ -0.61 -0.608480742634499
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3289  WP_000033690.1  E8XAI9  gsp  618 aa bifunctional glutathionylspermidine amidase/synthase 0.0048 ●○○○○ -0.61 -0.608366773306204
Porphyromonas gingivalis ATCC 33277  PGN_1426  WP_012458261.1  B2RKQ0  322 aa restriction endonuclease subunit M 3.2e-13 ●○○○○ -0.61 -0.608203725910955
Escherichia coli M12  CO715_14560  ATI06825.1  195 aa 4'-phosphopantetheinyl transferase AcpT 9.6e-7 ●○○○○ -0.61 -0.608112620306714
Escherichia coli M12  CO715_06770  ATI05444.1  231 aa septum site-determining protein MinC 1.5e-36 ●○○○○ -0.61 -0.607903974292465
Porphyromonas gingivalis ATCC 33277  PGN_1817  WP_012458555.1  B2RLU1  145 aa T9SS type A sorting domain-containing protein 4.8e-5 ●○○○○ -0.61 -0.607772030728597
Escherichia coli M12  CO715_11065  ATI06193.1  178 aa hypothetical protein 1.2e-49 ●○○○○ -0.61 -0.60706939023547
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0811  WP_001094775.1  E8XBP9  ybhC  427 aa putative acyl-CoA thioester hydrolase 0.0028 ●○○○○ -0.61 -0.606263837419415
Escherichia coli M12  CO715_00320  ATI04316.1  112 aa nitrogen regulatory protein P-II 1 2.2e-13 ●○○○○ -0.61 -0.606234806178474
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4309  AIK82854.1  462 aa aldehyde dehydrogenase family protein 2.6e-13 ●○○○○ -0.61 -0.605884501148651
Porphyromonas gingivalis ATCC 33277  PGN_1960  WP_012458643.1  B2RM83  cas1  338 aa type I-B CRISPR-associated endonuclease Cas1 4.6e-8 ●○○○○ -0.61 -0.605397307332418
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4511  AIK83049.1  701 aa ribonucleoside-diphosphate reductase, alpha subunit 3.1e-8 ●○○○○ -0.61 -0.605146372929327
Escherichia coli CFT073  c2052  AAN80512.1  Q8FH72  purR  341 aa Purine nucleotide synthesis repressor 0.015 ●○○○○ -0.6 -0.604873933882396
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0633  WP_000417097.1  E8X984  ynfH  255 aa hydrogenase 0.0029 ●○○○○ -0.6 -0.604025002582233
Escherichia coli M12  CO715_12245  ATI06410.1  295 aa dTDP-4-dehydrorhamnose reductase 5.6e-5 ●○○○○ -0.6 -0.603731054007488
Acinetobacter baumannii ATCC 17978  A1S_0305  ABO10773.2  A3M1H9  fadA  390 aa 3-ketoacyl-CoA thiolase 0.00015 ●○○○○ -0.6 -0.603642075935009
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3074  AIK81659.1  518 aa sodium-dependent inorganic phosphate (Pi) transporter family protein <1e-323 ●○○○○ -0.6 -0.60360811983208
Escherichia coli M12  CO715_04665  ATI05090.1  271 aa mannosyl-3-phosphoglycerate phosphatase-related protein 3.2e-9 ●○○○○ -0.6 -0.603522407993239
Acinetobacter baumannii ATCC 17978  A1S_1916  ABO12343.2  513 aa threonine dehydratase 8.7e-5 ●○○○○ -0.6 -0.603409052207133
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3411  AIK81968.1  104 aa PTS system, Lactose/Cellobiose specific IIB subunit 0.00091 ●○○○○ -0.6 -0.603144105277267
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1478  NP_231119.1  Q9K3D5  290 aa transposase OrfAB subunit B 5.8e-6 ●○○○○ -0.6 -0.603025304865311
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1077  WP_000374050.1  E8XE42  ycca  219 aa FtsH protease modulator YccA 0.00069 ●○○○○ -0.6 -0.6026828352401
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3106  AIK81687.1  101 aa PTS system, Lactose/Cellobiose specific IIB subunit 2.1e-12 ●○○○○ -0.6 -0.602482903851828
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2069  WP_000061500.1  E8XB56  272 aa helix-turn-helix domain-containing protein 0.0047 ●○○○○ -0.6 -0.602422610267902
Acinetobacter baumannii ATCC 17978  A1S_3028  ABO13425.1  137 aa putative tRNA-i(6)A37 modification enzyme 0.00071 ●○○○○ -0.6 -0.602039666018036
Retrieved entries 5,101–5,200 out of 36,363 total in 8.9 ms (Link to these results)