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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_21570  ATI08888.1  315 aa tRNA dihydrouridine(16) synthase DusC 0.001 ●○○○○ -0.43 -0.42930298609544
Escherichia coli M12  CO715_12490  ATI06450.1  258 aa transcriptional regulator ExuR 2.4e-6 ●○○○○ -0.43 -0.428051110009947
Escherichia coli M12  CO715_18790  ATI07582.1  121 aa hypothetical protein 7.2e-30 ●○○○○ -0.43 -0.426381941895956
Escherichia coli M12  CO715_14760  ATI06863.1  425 aa branched-chain amino acid ABC transporter permease 0.0058 ●○○○○ -0.43 -0.425964649867458
Escherichia coli M12  CO715_19305  ATI07674.1  537 aa peptide ABC transporter substrate-binding protein 7.0e-140 ●○○○○ -0.42 -0.421791729582481
Escherichia coli M12  CO715_15465  ATI06987.1  502 aa glycerol kinase 6.0e-6 ●○○○○ -0.42 -0.418036101326002
Escherichia coli M12  CO715_16000  ATI07081.1  243 aa fimbrial chaperone 4.4e-5 ●○○○○ -0.42 -0.417827455311753
Escherichia coli M12  CO715_10930  ATI06166.1  429 aa FAD-dependent oxidoreductase 1.5e-6 ●○○○○ -0.42 -0.416158287197762
Escherichia coli M12  CO715_23945  ATI08492.1  532 aa transcriptional regulator 2.5e-6 ●○○○○ -0.41 -0.414489119083771
Escherichia coli M12  CO715_11105  ATI06201.1  450 aa 6-phospho-beta-glucosidase <1e-323 ●○○○○ -0.41 -0.413237242998278
Escherichia coli M12  CO715_06375  ATI05377.1  137 aa DNA-binding protein H-NS 6.9e-38 ●○○○○ -0.41 -0.413237242998278
Escherichia coli M12  CO715_13685  ATI06665.1  197 aa TetR/AcrR family transcriptional regulator 0.00084 ●○○○○ -0.41 -0.411776720898536
Escherichia coli M12  CO715_05235  ATI05184.1  165 aa non-heme ferritin 3.0e-93 ●○○○○ -0.41 -0.411359428870038
Escherichia coli M12  CO715_04355  ATI05045.1  441 aa DNA-binding response regulator 5.4e-37 ●○○○○ -0.41 -0.410733490827292
Escherichia coli M12  CO715_12990  ATI08804.1  183 aa outer membrane lipid asymmetry maintenance protein MlaD 4.6e-5 ●○○○○ -0.41 -0.410316198798794
Escherichia coli M12  CO715_05385  ATI05210.1  188 aa VOC family protein 0.0013 ●○○○○ -0.41 -0.409064322713301
Escherichia coli M12  CO715_11060  ATI06192.1  286 aa fructosamine kinase family protein 8.2e-71 ●○○○○ -0.41 -0.40739515459931
Escherichia coli M12  CO715_00025  ATI04260.1  284 aa alpha/beta hydrolase 1.0e-10 ●○○○○ -0.41 -0.405934632499568
Escherichia coli M12  CO715_13845  ATI06694.1  184 aa YtfJ family protein 7.5e-13 ●○○○○ -0.41 -0.405308694456821
Escherichia coli M12  CO715_19910  ATI07783.1  590 aa multidrug ABC transporter permease/ATP-binding protein 1.8e-9 ●○○○○ -0.4 -0.404891402428323
Escherichia coli M12  CO715_05665  ATI05258.1  291 aa nucleic acid-binding protein 7.9e-24 ●○○○○ -0.4 -0.404682756414075
Escherichia coli M12  CO715_04030  ATI04982.1  408 aa phosphopentomutase 1.6e-21 ●○○○○ -0.4 -0.400927128157595
Escherichia coli M12  CO715_18615  ATI07552.1  102 aa PTS sorbitol transporter 3.9e-8 ●○○○○ -0.4 -0.4000925441006
Escherichia coli M12  CO715_10960  ATI06172.1  348 aa phospho-2-dehydro-3-deoxyheptonate aldolase Trp-sensitive 0.013 ●○○○○ -0.4 -0.399675252072102
Escherichia coli M12  CO715_23170  ATI08369.1  437 aa permease 1.4e-43 ●○○○○ -0.4 -0.398006083958111
Escherichia coli M12  CO715_20390  ATI07875.1  403 aa 3-(3-hydroxy-phenyl)propionate transporter MhpT 3.7e-36 ●○○○○ -0.4 -0.397588791929613
Escherichia coli M12  CO715_13115  ATI06564.1  291 aa N-acetylmannosamine kinase 0.002 ●○○○○ -0.4 -0.396754207872618
Escherichia coli M12  CO715_10450  ATI06080.1  467 aa class II fumarate hydratase 3.7e-6 ●○○○○ -0.4 -0.39633691584412
Escherichia coli M12  CO715_20260  ATI07850.1  471 aa alkaline phosphatase 1.9e-79 ●○○○○ -0.4 -0.395085039758627
Escherichia coli M12  CO715_08640  ATI05775.1  623 aa glutathione ABC transporter ATP-binding protein GsiA 8.7e-29 ●○○○○ -0.39 -0.394041809687383
Escherichia coli M12  CO715_02085  ATI04627.1  371 aa maltose/maltodextrin import ATP-binding protein MalK 0.037 ●○○○○ -0.39 -0.392372641573392
Escherichia coli M12  CO715_17285  ATI07317.1  301 aa hypothetical protein 2.6e-10 ●○○○○ -0.39 -0.391746703530645
Escherichia coli M12  CO715_24600  ATI08609.1  732 aa xanthine dehydrogenase 7.9e-118 ●○○○○ -0.39 -0.390286181430903
Escherichia coli M12  CO715_11790  ATI06327.1  193 aa modulator of drug activity B 0.0084 ●○○○○ -0.39 -0.389451597373908
Escherichia coli M12  CO715_19890  ATI07779.1  286 aa acyl-CoA thioesterase II 9.0e-22 ●○○○○ -0.39 -0.388408367302663
Escherichia coli M12  CO715_09735  ATI05964.1  317 aa LysR family transcriptional regulator 2.8e-8 ●○○○○ -0.39 -0.388408367302663
Escherichia coli M12  CO715_10395  ATI06071.1  344 aa pheromone autoinducer 2 transporter 9.2e-10 ●○○○○ -0.39 -0.386947845202921
Escherichia coli M12  CO715_03775  ATI04936.1  550 aa 4-amino-4-deoxy-L-arabinose lipid A transferase 7.4e-46 ●○○○○ -0.39 -0.38527867708893
Escherichia coli M12  CO715_11125  ATI06204.1  106 aa PTS sugar transporter subunit IIB 7.5e-5 ●○○○○ -0.38 -0.384652739046184
Escherichia coli M12  CO715_15230  ATI06946.1  413 aa AGE family epimerase/isomerase 0.0011 ●○○○○ -0.38 -0.384444093031935
Escherichia coli M12  CO715_24310  ATI08559.1  910 aa type VI secretion system ATPase TssH 2.2e-21 ●○○○○ -0.38 -0.381940340860949
Escherichia coli M12  CO715_03000  ATI04796.1  283 aa pyridoxine kinase 0.0011 ●○○○○ -0.38 -0.381105756803953
Escherichia coli M12  CO715_20195  ATI07838.1  302 aa fructokinase 0.022 ●○○○○ -0.38 -0.379436588689962
Escherichia coli M12  CO715_06555  ATI05406.1  92 aa hypothetical protein 7.1e-13 ●○○○○ -0.38 -0.376932836518976
Escherichia coli M12  CO715_10125  ATI06030.1  71 aa lysis protein S 1.1e-16 ●○○○○ -0.38 -0.376306898476229
Escherichia coli M12  CO715_11045  ATI06189.1  252 aa DUF481 domain-containing protein 2.5e-7 ●○○○○ -0.37 -0.374637730362239
Escherichia coli M12  CO715_25145  ATI08677.1  115 aa antirestriction protein 5.4e-12 ●○○○○ -0.37 -0.373385854276745
Escherichia coli M12  CO715_13060  ATI06555.1  210 aa hypothetical protein 2.7e-19 ●○○○○ -0.37 -0.372342624205501
Escherichia coli M12  CO715_16655  ATI07204.1  388 aa Na+/H+ antiporter NhaA 0.00045 ●○○○○ -0.37 -0.372342624205501
Escherichia coli M12  CO715_04685  ATI05093.1  207 aa helix-turn-helix transcriptional regulator 6.6e-39 ●○○○○ -0.37 -0.370464810077261
Escherichia coli M12  CO715_04335  ATI08722.1  231 aa DUF1481 domain-containing protein 3.1e-77 ●○○○○ -0.37 -0.370047518048764
Escherichia coli M12  CO715_16710  ATI07213.1  114 aa hypothetical protein 7.6e-15 ●○○○○ -0.37 -0.366500535806533
Escherichia coli M12  CO715_11925  ATI06353.1  47 aa carboxymethylenebutenolidase 1.0e-6 ●○○○○ -0.37 -0.366291889792284
Escherichia coli M12  CO715_22960  ATI08334.1  286 aa hypothetical protein 2.7e-12 ●○○○○ -0.36 -0.363996783635547
Escherichia coli M12  CO715_00305  ATI04313.1  475 aa two-component sensor histidine kinase 5.6e-5 ●○○○○ -0.36 -0.363579491607049
Escherichia coli M12  CO715_05605  ATI08736.1  479 aa 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF 0.00098 ●○○○○ -0.36 -0.362953553564302
Escherichia coli M12  CO715_16920  ATI07250.1  479 aa anaerobic nitric oxide reductase flavorubredoxin 5.0e-18 ●○○○○ -0.36 -0.362536261535805
Escherichia coli M12  CO715_23430  ATI08404.1  94 aa malate transporter 3.2e-9 ●○○○○ -0.36 -0.361284385450311
Escherichia coli M12  CO715_20475  ATI07890.1  427 aa cytosine deaminase 0.0046 ●○○○○ -0.36 -0.361075739436062
Escherichia coli M12  CO715_04470  ATI05057.1  484 aa AMP nucleosidase 3.6e-5 ●○○○○ -0.36 -0.359823863350569
Escherichia coli M12  CO715_02285  ATI04662.1  143 aa rhodanese-like domain-containing protein 8.3e-7 ●○○○○ -0.36 -0.359615217336321
Escherichia coli M12  CO715_24950  ATI08658.1  157 aa antirestriction protein 1.9e-11 ●○○○○ -0.36 -0.358363341250827
Escherichia coli M12  CO715_02800  ATI04760.1  191 aa GDP-mannose pyrophosphatase NudK 0.0016 ●○○○○ -0.36 -0.357737403208081
Escherichia coli M12  CO715_03735  ATI04930.1  556 aa 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 0.0013 ●○○○○ -0.36 -0.357528757193832
Escherichia coli M12  CO715_09955  ATI06005.1  1293 aa enterobactin synthase subunit F 6.7e-25 ●○○○○ -0.36 -0.357320111179583
Escherichia coli M12  CO715_16860  ATI07238.1  166 aa regulatory protein RecX 3.8e-8 ●○○○○ -0.36 -0.35606823509409
Escherichia coli M12  CO715_05885  ATI05290.1  859 aa phage tail tape measure protein 2.0e-20 ●○○○○ -0.36 -0.355233651037094
Escherichia coli M12  CO715_22005  ATI08169.1  373 aa GDP-mannose 4,6-dehydratase 2.2e-9 ●○○○○ -0.35 -0.350852084737868
Escherichia coli M12  CO715_22555  ATI08264.1  188 aa succinate-acetate/proton symporter SatP 2.6e-27 ●○○○○ -0.35 -0.350434792709371
Escherichia coli M12  CO715_01235  ATI04475.1  284 aa L-ribulose-5-phosphate 3-epimerase UlaE 5.2e-5 ●○○○○ -0.35 -0.350434792709371
Escherichia coli M12  CO715_19210  ATI07658.1  377 aa phosphoporin PhoE 1.6e-28 ●○○○○ -0.35 -0.349600208652375
Escherichia coli M12  CO715_00150  ATI04284.1  725 aa intimin-like inverse autotransporter protein SinH 2.7e-79 ●○○○○ -0.35 -0.347931040538384
Escherichia coli M12  CO715_20000  ATI07801.1  315 aa cytochrome ubiquinol oxidase subunit II 1.1e-51 ●○○○○ -0.35 -0.345427288367398
Escherichia coli M12  CO715_14800  ATI06871.1  146 aa hypothetical protein 1.9e-22 ●○○○○ -0.34 -0.344592704310403
Escherichia coli M12  CO715_05655  ATI05256.1  411 aa integrase 8.1e-14 ●○○○○ -0.34 -0.344175412281905
Escherichia coli M12  CO715_00955  ATI04426.1  319 aa transcriptional regulator 0.026 ●○○○○ -0.34 -0.343549474239158
Escherichia coli M12  CO715_09050  ATI05852.1  346 aa galactose-1-epimerase 0.0057 ●○○○○ -0.34 -0.342506244167914
Escherichia coli M12  CO715_02715  ATI04744.1  672 aa hydrogenase 4 subunit B 2.3e-64 ●○○○○ -0.34 -0.342088952139416
Escherichia coli M12  CO715_00015  ATI04258.1  379 aa 3-phenylpropionate MFS transporter 0.0017 ●○○○○ -0.34 -0.342088952139416
Escherichia coli M12  CO715_13725  ATI06671.1  898 aa magnesium-translocating P-type ATPase 6.2e-21 ●○○○○ -0.34 -0.341254368082421
Escherichia coli M12  CO715_16490  ATI07172.1  620 aa glutathione-regulated potassium-efflux system protein KefC 1.9e-9 ●○○○○ -0.34 -0.341254368082421
Escherichia coli M12  CO715_09030  ATI05848.1  490 aa molybdate ABC transporter ATP-binding protein ModF 0.0067 ●○○○○ -0.34 -0.341254368082421
Escherichia coli M12  CO715_09575  ATI05934.1  474 aa tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB 5.8e-8 ●○○○○ -0.34 -0.341045722068172
Escherichia coli M12  CO715_20535  ATI07901.1  440 aa pyrimidine utilization transport protein G 0.035 ●○○○○ -0.34 -0.341045722068172
Escherichia coli M12  CO715_17155  ATI07292.1  216 aa type I-E CRISPR-associated protein Cas6/Cse3/CasE 0.0065 ●○○○○ -0.34 -0.338750615911434
Escherichia coli M12  CO715_23870  ATI08479.1  431 aa glucose-1-phosphate adenylyltransferase 1.4e-71 ●○○○○ -0.33 -0.334786341640706
Escherichia coli M12  CO715_14625  ATI06837.1  83 aa acyl carrier protein 0.0038 ●○○○○ -0.33 -0.333117173526715
Escherichia coli M12  CO715_24495  ATI08591.1  97 aa antitoxin YafN 0.0014 ●○○○○ -0.33 -0.332908527512466
Escherichia coli M12  CO715_08485  ATI05746.1  281 aa putrescine ABC transporter permease PotI 0.0015 ●○○○○ -0.33 -0.332073943455471
Escherichia coli M12  CO715_13785  ATI06683.1  331 aa sugar ABC transporter permease YjfF 0.0031 ●○○○○ -0.33 -0.330196129327231
Escherichia coli M12  CO715_09400  ATI05907.1  68 aa DUF2517 domain-containing protein 1.2e-56 ●○○○○ -0.33 -0.329778837298733
Escherichia coli M12  CO715_10905  ATI06161.1  383 aa acyl-CoA dehydrogenase 1.8e-16 ●○○○○ -0.33 -0.329778837298733
Escherichia coli M12  CO715_21740  ATI08119.1  224 aa fimbrial assembly protein 5.9e-108 ●○○○○ -0.33 -0.329361545270236
Escherichia coli M12  CO715_17875  ATI07420.1  442 aa chlorohydrolase 7.7e-22 ●○○○○ -0.33 -0.32852696121324
Escherichia coli M12  CO715_22405  ATI08240.1  498 aa insulinase family protein 6.1e-91 ●○○○○ -0.33 -0.325814563028005
Escherichia coli M12  CO715_22630  ATI08276.1  474 aa two-component system sensor histidine kinase CreC 2.3e-8 ●○○○○ -0.33 -0.325605917013756
Escherichia coli M12  CO715_14130  ATI06744.1  128 aa hypothetical protein 2.6e-5 ●○○○○ -0.32 -0.324562686942512
Escherichia coli M12  CO715_05240  ATI05185.1  107 aa hypothetical protein 2.0e-9 ●○○○○ -0.32 -0.324354040928263
Escherichia coli M12  CO715_16540  ATI07182.1  517 aa ATP-dependent acyl-CoA ligase 1.2e-6 ●○○○○ -0.32 -0.324354040928263
Escherichia coli M12  CO715_06620  ATI05416.1  340 aa iron ABC transporter substrate-binding protein 0.0043 ●○○○○ -0.32 -0.322684872814272
Retrieved entries 1,601–1,700 out of 3,550 total in 51 ms (Link to these results)