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Pathogen
Any pathogen
Acinetobacter baumannii ATCC 17978
Campylobacter jejuni subsp. jejuni 81-176
Escherichia coli CFT073
Escherichia coli M12
Escherichia coli O157:H7 str. EDL933
Haemophilus influenzae Rd KW20
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
Mycobacterium avium subsp. paratuberculosis K10
Porphyromonas gingivalis ATCC 33277
Salmonella enterica Serovar Typhimurium SL1344
Salmonella enterica Serovar Typhimurium ST4 74
Serratia marcescens Strain UMH9
Streptococcus pyogenes M1 5448
Vibrio cholerae O1 biovar El Tor str. N16961
Vibrio parahaemolyticus RIMD 2210633
Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):
Download Table
Pathogen
Locus
Protein
UniProt
Gene
Length
Product
p-Value
Fitness z-Score
Precise fitness z-Score
Mycobacterium avium subsp. paratuberculosis K10
MAP_1198
AAS03515.1
Q740Z4
545 aa
hypothetical protein
0.0085
○○○○○ 2.34
2.33797749138249
Mycobacterium avium subsp. paratuberculosis K10
MAP_2556c
AAS04873.1
Q73WV4
133 aa
hypothetical protein
0.0085
○○○○○ 2.34
2.33940931613557
Streptococcus pyogenes M1 5448
SP5448_02335
WP_011106637.1
150 aa
terminase small subunit
0.0069
○○○○○ 2.34
2.3397164779707
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_1052
WP_002869123.1
A0A0H3PH78
1005 aa
multidrug efflux RND transporter permease subunit CmeF
0.013
○○○○○ 2.34
2.34011747046
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0697
WP_002868850.1
A0A0H3PA66
dcuB
474 aa
anaerobic C4-dicarboxylate transporter
0.013
○○○○○ 2.34
2.34217843988
Serratia marcescens Strain UMH9
BVG96_19650
ASL99704.1
231 aa
LuxR family transcriptional regulator
0.0023
○○○○○ 2.34
2.34223473374282
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_1406
AIK80029.1
197 aa
bacterial regulatory, tetR family protein
9.9e-6
○○○○○ 2.35
2.34673028131647
Mycobacterium avium subsp. paratuberculosis K10
MAP_3242
AAS05790.1
Q73UX4
346 aa
hypothetical protein
0.0083
○○○○○ 2.35
2.34725605272547
Escherichia coli M12
CO715_20745
ATI07936.1
75 aa
YceK/YidQ family lipoprotein
7.7e-14
○○○○○ 2.35
2.34840140159965
Mycobacterium avium subsp. paratuberculosis K10
MAP_1324
AAS03641.1
Q740M6
508 aa
hypothetical protein
0.0083
○○○○○ 2.35
2.34906006848304
Escherichia coli M12
CO715_21060
ATI08881.1
210 aa
TetR/AcrR family transcriptional regulator
7.3e-6
○○○○○ 2.35
2.34965327768514
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_1477
AIK80098.1
342 aa
fe(3+) ions import ATP-binding protein FbpC
<1e-323
○○○○○ 2.35
2.35006171633444
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_4720
AIK83254.1
96 aa
BMC domain protein
7.8e-10
○○○○○ 2.35
2.35068278995382
Mycobacterium avium subsp. paratuberculosis K10
MAP_0207
AAS02524.1
Q745K0
261 aa
hypothetical protein
0.0082
○○○○○ 2.35
2.35467659759445
Mycobacterium avium subsp. paratuberculosis K10
MAP_2826
AAS05143.1
Q73W34
sigB
332 aa
SigB
0.0081
○○○○○ 2.36
2.35733588507167
Mycobacterium avium subsp. paratuberculosis K10
MAP_2342c
AAS04659.1
Q73XG7
521 aa
hypothetical protein
0.0081
○○○○○ 2.36
2.35736208943639
Mycobacterium avium subsp. paratuberculosis K10
MAP_2986c
AAS05303.1
Q73VM7
glnD
814 aa
GlnD
0.0081
○○○○○ 2.36
2.35859648969294
Streptococcus pyogenes M1 5448
SP5448_09010
WP_010922743.1
346 aa
elongation factor Ts
0.00017
○○○○○ 2.36
2.36182721742619
Mycobacterium avium subsp. paratuberculosis K10
MAP_3695
AAS06245.1
Q73TM3
357 aa
hypothetical protein
0.008
○○○○○ 2.36
2.36311605283451
Mycobacterium avium subsp. paratuberculosis K10
MAP_1693c
AAS04010.1
Q73ZB0
188 aa
hypothetical protein
0.008
○○○○○ 2.36
2.36345916025271
Streptococcus pyogenes M1 5448
SP5448_02555
WP_010922573.1
141 aa
galactose-6-phosphate isomerase subunit LacA
0.0024
○○○○○ 2.36
2.36374989042232
Vibrio parahaemolyticus RIMD 2210633
VP_1838
BAC60101.1
Q87NN0
30 aa
hypothetical protein
0.021
○○○○○ 2.36
2.36396124248734
Mycobacterium avium subsp. paratuberculosis K10
MAP_1031c
AAS03348.1
Q741Q6
speE
523 aa
SpeE
0.008
○○○○○ 2.36
2.36463056762382
Mycobacterium avium subsp. paratuberculosis K10
MAP_3865c
AAS06415.1
Q73T54
298 aa
hypothetical protein
0.0079
○○○○○ 2.37
2.36673597996357
Mycobacterium avium subsp. paratuberculosis K10
MAP_1490
AAS03807.1
Q73ZW1
293 aa
hypothetical protein
0.0079
○○○○○ 2.37
2.36986046613912
Mycobacterium avium subsp. paratuberculosis K10
MAP_2217c
AAS04534.1
P60791
lepA
660 aa
LepA
0.0078
○○○○○ 2.37
2.37211172488364
Porphyromonas gingivalis ATCC 33277
PGN_0026
WP_004583429.1
B2RGQ0
158 aa
cytidine deaminase
2.7e-9
○○○○○ 2.38
2.37504829266102
Mycobacterium avium subsp. paratuberculosis K10
MAP_3344c
AAS05894.1
Q73UM2
384 aa
hypothetical protein
0.0078
○○○○○ 2.38
2.37580179219102
Escherichia coli M12
CO715_22575
ATI08267.1
258 aa
peroxide stress protein YaaA
4.1e-10
○○○○○ 2.38
2.3759426754805
Mycobacterium avium subsp. paratuberculosis K10
MAP_3186c
AAS05734.1
Q73V30
114 aa
hypothetical protein
0.0078
○○○○○ 2.38
2.37636863552143
Escherichia coli M12
CO715_23590
ATI08431.1
292 aa
2-hydroxy-3-oxopropionate reductase
6.3e-9
○○○○○ 2.38
2.37698590555174
Mycobacterium avium subsp. paratuberculosis K10
MAP_3728
AAS06278.1
Q73TJ0
345 aa
hypothetical protein
0.0078
○○○○○ 2.38
2.37713995467768
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_1450
AIK80071.1
415 aa
histidine phosphatase super family protein
<1e-323
○○○○○ 2.38
2.37721600365023
Vibrio parahaemolyticus RIMD 2210633
VPA_0597
BAC61940.1
Q87IK9
57 aa
hypotheteical protein
0.029
○○○○○ 2.38
2.3782908228402
Mycobacterium avium subsp. paratuberculosis K10
MAP_3693
AAS06243.1
Q73TM5
fadA2
448 aa
FadA2
0.0077
○○○○○ 2.38
2.37854125700749
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_2096
AIK80701.1
110 aa
DNA-binding protein, YbaB/EbfC family
0.00014
○○○○○ 2.38
2.3786495301739
Mycobacterium avium subsp. paratuberculosis K10
MAP_4048c
AAS06598.1
Q73SM5
fadD8
533 aa
FadD8
0.0077
○○○○○ 2.38
2.38036007512638
Mycobacterium avium subsp. paratuberculosis K10
MAP_2016
AAS04333.1
Q73YE0
170 aa
hypothetical protein
0.0076
○○○○○ 2.38
2.38308575395406
Vibrio parahaemolyticus RIMD 2210633
VP_2167
BAC60430.1
Q87MR4
94 aa
conserved hypothetical protein
0.02
○○○○○ 2.38
2.38461863498336
Mycobacterium avium subsp. paratuberculosis K10
MAP_3014
AAS05562.1
Q73VJ9
477 aa
hypothetical protein
0.0076
○○○○○ 2.39
2.38648044529367
Mycobacterium avium subsp. paratuberculosis K10
MAP_3674
AAS06224.1
Q73TP4
52 aa
hypothetical protein
0.0076
○○○○○ 2.39
2.38708209659505
Streptococcus pyogenes M1 5448
SP5448_03120
WP_002989022.1
187 aa
hypothetical protein
0.025
○○○○○ 2.39
2.38778330287394
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0970
WP_009882583.1
A0A0H3PA23
448 aa
hypothetical protein
0.012
○○○○○ 2.39
2.38941957106
Escherichia coli M12
CO715_08515
ATI05752.1
300 aa
30S ribosomal protein S6--L-glutamate ligase
0.045
○○○○○ 2.39
2.39075654249217
Streptococcus pyogenes M1 5448
SP5448_08670
WP_003059481.1
267 aa
ABC transporter ATP-binding protein
0.0094
○○○○○ 2.39
2.3916286488662
Mycobacterium avium subsp. paratuberculosis K10
MAP_0379c
AAS02696.1
Q744G2
rsbR
300 aa
RsbR
0.0075
○○○○○ 2.39
2.3917643250735
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_1022
AIK79645.1
550 aa
major Facilitator Superfamily protein
<1e-323
○○○○○ 2.39
2.3920346599957
Mycobacterium avium subsp. paratuberculosis K10
MAP_4257
AAS06807.1
Q73S19
gadB
463 aa
GadB
0.0075
○○○○○ 2.39
2.39307250228419
Vibrio cholerae O1 biovar El Tor str. N16961
VC_0046
NP_229705.1
Q9KVU3
def1
169 aa
peptide deformylase
0.012
○○○○○ 2.39
2.3941383019303
Mycobacterium avium subsp. paratuberculosis K10
MAP_0336c
AAS02653.1
Q744K5
400 aa
hypothetical protein
0.0074
○○○○○ 2.4
2.39501926820169
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0652
WP_002785900.1
A0A0H3PAZ6
hypB
247 aa
hydrogenase accessory protein HypB
0.012
○○○○○ 2.4
2.39712107471
Streptococcus pyogenes M1 5448
SP5448_01010
WP_002987933.1
71 aa
IS3 family transposase
0.03
○○○○○ 2.4
2.39835800435265
Streptococcus pyogenes M1 5448
SP5448_04745
WP_010922368.1
203 aa
alkaline shock response membrane anchor protein AmaP
0.027
○○○○○ 2.4
2.40028067734878
Vibrio parahaemolyticus RIMD 2210633
VP_1684
BAC59947.1
Q87P34
166 aa
hypothetical protein
0.019
○○○○○ 2.4
2.40149105297726
Mycobacterium avium subsp. paratuberculosis K10
MAP_4121
AAS06671.1
Q73SF3
1407 aa
hypothetical protein
0.0073
○○○○○ 2.4
2.40317860062226
Mycobacterium avium subsp. paratuberculosis K10
MAP_0986c
AAS03303.1
Q741V1
lysA
444 aa
LysA_1
0.0072
○○○○○ 2.41
2.4076298798988
Mycobacterium avium subsp. paratuberculosis K10
MAP_2272c
AAS04589.1
Q73XN7
419 aa
hypothetical protein
0.0071
○○○○○ 2.41
2.4112482205456
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_1516
WP_002855997.1
A1W1D0
dapF
249 aa
diaminopimelate epimerase
0.011
○○○○○ 2.41
2.41178448766
Mycobacterium avium subsp. paratuberculosis K10
MAP_4071
AAS06621.1
Q73SK2
galT
365 aa
GalT
0.0071
○○○○○ 2.41
2.41307012518578
Mycobacterium avium subsp. paratuberculosis K10
MAP_4191c
AAS06741.1
Q73S85
356 aa
hypothetical protein
0.0071
○○○○○ 2.41
2.41401881439128
Acinetobacter baumannii ATCC 17978
A1S_1586
ABO12013.2
128 aa
EsvK1
0.0001
○○○○○ 2.41
2.41422676454405
Streptococcus pyogenes M1 5448
SP5448_06350
WP_002990245.1
419 aa
uracil permease
0.0077
○○○○○ 2.42
2.41566206131782
Streptococcus pyogenes M1 5448
SP5448_08735
WP_076640004.1
64 aa
hypothetical protein
0.023
○○○○○ 2.42
2.41566206131782
Streptococcus pyogenes M1 5448
SP5448_08735
WP_010922715.1
529 aa
M protein trans-acting positive regulator
0.023
○○○○○ 2.42
2.41566206131782
Mycobacterium avium subsp. paratuberculosis K10
MAP_2552
AAS04869.1
Q73WV8
454 aa
hypothetical protein
0.0071
○○○○○ 2.42
2.41653414944065
Mycobacterium avium subsp. paratuberculosis K10
MAP_4188
AAS06738.1
Q73S88
sppA
595 aa
SppA
0.007
○○○○○ 2.42
2.41785275388556
Mycobacterium avium subsp. paratuberculosis K10
MAP_2734
AAS05051.1
Q73WC6
446 aa
hypothetical protein
0.007
○○○○○ 2.42
2.41951834573203
Mycobacterium avium subsp. paratuberculosis K10
MAP_2575c
AAS04892.1
Q73WT5
383 aa
hypothetical protein
0.007
○○○○○ 2.42
2.41962090586207
Mycobacterium avium subsp. paratuberculosis K10
MAP_4015
AAS06565.1
Q73SQ8
105 aa
hypothetical protein
0.007
○○○○○ 2.42
2.41984154714912
Mycobacterium avium subsp. paratuberculosis K10
MAP_1228
AAS03545.1
Q740W4
lipL
428 aa
LipL
0.007
○○○○○ 2.42
2.41999945742615
Vibrio parahaemolyticus RIMD 2210633
VP_1111
BAC59374.1
Q87QN8
88 aa
putative zinc-finger containing protein
0.019
○○○○○ 2.42
2.42025879676509
Mycobacterium avium subsp. paratuberculosis K10
MAP_2223c
AAS04540.1
Q73XT6
558 aa
hypothetical protein
0.007
○○○○○ 2.42
2.42070308013714
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
VK055_1018
AIK79641.1
424 aa
glutamate dehydrogenase
<1e-323
○○○○○ 2.42
2.42239980606523
Acinetobacter baumannii ATCC 17978
A1S_0645
ABO11094.2
376 aa
hypothetical protein
2.6e-29
○○○○○ 2.42
2.42383501031892
Mycobacterium avium subsp. paratuberculosis K10
MAP_1111
AAS03428.1
Q741H9
frdA
906 aa
FrdA
0.0069
○○○○○ 2.43
2.4259181435273
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_1526
WP_002851457.1
A1W1E0
pxpA
255 aa
LamB/YcsF family protein
0.011
○○○○○ 2.43
2.42723166646
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0671
WP_002852330.1
A0A0H3PJ41
414 aa
PleD family two-component system response regulator
0.011
○○○○○ 2.43
2.42953808408
Mycobacterium avium subsp. paratuberculosis K10
MAP_4127c
AAS06677.1
Q73SE7
251 aa
hypothetical protein
0.0068
○○○○○ 2.43
2.42955616973115
Mycobacterium avium subsp. paratuberculosis K10
MAP_2675c
AAS04992.1
Q73WI5
167 aa
hypothetical protein
0.0068
○○○○○ 2.43
2.43049376229825
Escherichia coli M12
CO715_01730
ATI04561.1
338 aa
phosphonate ABC transporter substrate-binding protein
7.6e-5
○○○○○ 2.43
2.4314425152707
Mycobacterium avium subsp. paratuberculosis K10
MAP_1021c
AAS03338.1
Q741R6
280 aa
hypothetical protein
0.0068
○○○○○ 2.43
2.43429121590451
Escherichia coli M12
CO715_03570
ATI04898.1
184 aa
phosphodiesterase YfcE
0.00028
○○○○○ 2.43
2.43498949751293
Mycobacterium avium subsp. paratuberculosis K10
MAP_0676
AAS02993.1
Q743A9
346 aa
hypothetical protein
0.0067
○○○○○ 2.44
2.43508894327222
Mycobacterium avium subsp. paratuberculosis K10
MAP_2100
AAS04417.1
Q73Y57
586 aa
hypothetical protein
0.0067
○○○○○ 2.44
2.43787806782772
Escherichia coli O157:H7 str. EDL933
Z3494
AAG57367.1
396 aa
putative antibiotic efflux protein
0.0092
○○○○○ 2.44
2.43813309305108
Mycobacterium avium subsp. paratuberculosis K10
MAP_1657
AAS03974.1
Q73ZE6
300 aa
hypothetical protein
0.0067
○○○○○ 2.44
2.43872094111631
Acinetobacter baumannii ATCC 17978
A1S_1693
ABO12120.2
334 aa
putative adenine-specific methylase
0.022
○○○○○ 2.44
2.43898749253902
Streptococcus pyogenes M1 5448
SP5448_00675
WP_011285355.1
105 aa
thioredoxin family protein
0.011
○○○○○ 2.44
2.44450215625976
Streptococcus pyogenes M1 5448
SP5448_03505
WP_010922204.1
88 aa
hypothetical protein
0.037
○○○○○ 2.45
2.44642482925589
Mycobacterium avium subsp. paratuberculosis K10
MAP_0760
AAS03077.1
Q742S5
340 aa
hypothetical protein
0.0065
○○○○○ 2.45
2.44764069525272
Streptococcus pyogenes M1 5448
SP5448_02880
WP_002983660.1
246 aa
Stp1/IreP family PP2C-type Ser/Thr phosphatase
0.016
○○○○○ 2.45
2.44834750225202
Mycobacterium avium subsp. paratuberculosis K10
MAP_3881
AAS06431.1
Q73T38
296 aa
hypothetical protein
0.0064
○○○○○ 2.45
2.45392594190317
Vibrio parahaemolyticus RIMD 2210633
VPA_1179
BAC62522.1
Q87GY6
50 aa
hypothetical protein
0.024
○○○○○ 2.46
2.45552403073082
Escherichia coli M12
CO715_04320
ATI05039.1
223 aa
endonuclease V
7.6e-5
○○○○○ 2.46
2.45564545292356
Mycobacterium avium subsp. paratuberculosis K10
MAP_1424c
AAS03741.1
Q740C7
152 aa
hypothetical protein
0.0064
○○○○○ 2.46
2.4579110287288
Mycobacterium avium subsp. paratuberculosis K10
MAP_3428c
AAS05978.1
Q73UE0
235 aa
hypothetical protein
0.0064
○○○○○ 2.46
2.45875347900366
Mycobacterium avium subsp. paratuberculosis K10
MAP_1875c
AAS04192.1
Q73YT0
901 aa
hypothetical protein
0.0064
○○○○○ 2.46
2.45906168306087
Campylobacter jejuni subsp. jejuni 81-176
CJJ81176_0759
WP_002869375.1
A0A0H3PAP5
642 aa
hypothetical protein
0.01
○○○○○ 2.46
2.46068275413
Escherichia coli M12
CO715_04535
ATI05070.1
600 aa
ABC transporter ATP-binding protein
0.00034
○○○○○ 2.46
2.46127889530828
Porphyromonas gingivalis ATCC 33277
PGN_1611
WP_012458405.1
B2RL85
485 aa
internalin
1.6e-5
○○○○○ 2.46
2.46255504516591
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