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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_03310  ATI04849.1  246 aa hypothetical protein 2.5e-47 ●●○○○ -1.2 -1.20484022105846
Escherichia coli M12  CO715_17250  ATI07310.1  261 aa oxidoreductase 2.4e-20 ●●○○○ -1.2 -1.20484022105846
Escherichia coli M12  CO715_18640  ATI07557.1  400 aa ERCC4 helicase 6.5e-20 ●●○○○ -1.2 -1.20463157504421
Escherichia coli M12  CO715_15360  ATI06970.1  312 aa HTH-type transcriptional activator RhaR 0.00092 ●●○○○ -1.2 -1.20421428301571
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3160  WP_000056576.1  E8X9I5  lysA  420 aa diaminopimelate decarboxylase 0.023 ●●○○○ -1.2 -1.20413615735808
Escherichia coli M12  CO715_08130  ATI05682.1  297 aa hypothetical protein 7.3e-35 ●●○○○ -1.2 -1.20400563700146
Escherichia coli M12  CO715_09355  ATI05899.1  218 aa hypothetical protein 0.00039 ●●○○○ -1.2 -1.20337969895872
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3162  AIK81734.1  316 aa magnesium and cobalt transport protein CorA <1e-323 ●●○○○ -1.2 -1.20308491886529
Escherichia coli M12  CO715_21565  ATI08089.1  132 aa hypothetical protein 6.2e-5 ●●○○○ -1.2 -1.20296240693022
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2714  WP_001189503.1  E8XHI7  498 aa S49 family peptidase 0.00012 ●●○○○ -1.2 -1.20150254258481
Escherichia coli M12  CO715_20415  ATI07880.1  314 aa 2,3-dihydroxyphenylpropionate/2, 3-dihydroxicinnamic acid 1,2-dioxygenase 8.9e-44 ●●○○○ -1.2 -1.20129323881623
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4122  AIK82668.1  546 aa thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein 9.8e-14 ●●○○○ -1.2 -1.20064683272384
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3852  AIK82402.1  472 aa glutamate synthase (NADPH) small chain glutamatesynthase, small subunit <1e-323 ●●○○○ -1.2 -1.2005304649366
Escherichia coli M12  CO715_15635  ATI07018.1  383 aa acetylornithine deacetylase 2.5e-7 ●●○○○ -1.2 -1.19983271671648
Escherichia coli M12  CO715_20895  ATI07966.1  313 aa flagellar assembly peptidoglycan hydrolase FlgJ 0.00016 ●●○○○ -1.2 -1.19962407070224
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0072  CBW16173.1  A0A0H3N8X1  caiC  517 aa probable crotonobetaine/carnitine-CoA ligase 0.011 ●●○○○ -1.2 -1.1995075826128
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1972  AIK80578.1  297 aa binding-protein-dependent transport system innermembrane component family protein 3.4e-5 ●●○○○ -1.2 -1.19936578365059
Escherichia coli M12  CO715_05400  ATI05213.1  809 aa molybdopterin guanine dinucleotide-containing S/N-oxide reductase 5.2e-10 ●●○○○ -1.2 -1.19920677867374
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3545  AIK82101.1  104 aa ysaB-like lipofamily protein 2.9e-6 ●●○○○ -1.2 -1.19909054418972
Escherichia coli M12  CO715_21935  ATI08156.1  1105 aa diguanylate cyclase 1.9e-49 ●●○○○ -1.2 -1.19837219461674
Escherichia coli M12  CO715_03395  ATI04864.1  156 aa fimbrial protein 0.00011 ●●○○○ -1.2 -1.19816354860249
Escherichia coli M12  CO715_04085  ATI04993.1  190 aa peptidylprolyl isomerase A 8.9e-5 ●●○○○ -1.2 -1.19753761055975
Escherichia coli M12  CO715_03390  ATI04863.1  204 aa fimbrial protein 0.00053 ●●○○○ -1.2 -1.19712031853125
Escherichia coli M12  CO715_09310  ATI05891.1  427 aa type II citrate synthase 3.0e-10 ●●○○○ -1.2 -1.196911672517
Escherichia coli M12  CO715_06635  ATI05419.1  270 aa SAM-dependent methyltransferase 1.8e-5 ●●○○○ -1.2 -1.196911672517
Escherichia coli M12  CO715_07040  ATI05491.1  299 aa Replication protein O 1.9e-9 ●●○○○ -1.2 -1.19670302650275
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1720  WP_000481166.1  E8XKS0  osmB  72 aa osmotically-inducible lipoprotein OsmB 2.3e-7 ●●○○○ -1.2 -1.19653215281428
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1547  NP_231187.1  Q9KRT8  457 aa biopolymer transport protein ExbB-like protein 2.1e-11 ●●○○○ -1.2 -1.19530330238556
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1290  NP_230935.1  Q9KSG6  236 aa DNA polymerase III subunit epsilon 7.6e-8 ●●○○○ -1.19 -1.19400861335544
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4361  AIK82904.1  378 aa lactaldehyde reductase 9.4e-12 ●●○○○ -1.19 -1.19311353782882
Escherichia coli M12  CO715_06260  ATI05357.1  253 aa AraC family transcriptional regulator 1.1e-186 ●●○○○ -1.19 -1.19294739824627
Escherichia coli M12  CO715_13220  ATI06583.1  90 aa hypothetical protein 0.034 ●●○○○ -1.19 -1.19294739824627
Escherichia coli M12  CO715_23930  ATI08489.1  108 aa thiosulfate sulfurtransferase 0.039 ●●○○○ -1.19 -1.19294739824627
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0169  WP_000384308.1  E8XHV8  yacl  120 aa UPF0231 family protein 2.4e-5 ●●○○○ -1.19 -1.1928091398696
Escherichia coli CFT073  c1020  AAN79492.1  A0A0H2V5P1  130 aa Hypothetical protein 0.026 ●●○○○ -1.19 -1.19234503212158
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1439  NP_231082.1  Q9KS22  326 aa cytochrome c oxidase subunit CcoP 4.2e-9 ●●○○○ -1.19 -1.19219155354932
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4739  WP_000820693.1  E8XCI1  140 aa PTS sugar transporter subunit IIA 0.019 ●●○○○ -1.19 -1.19077075480281
Escherichia coli M12  CO715_13970  ATI06715.1  274 aa hypothetical protein 1.4e-26 ●●○○○ -1.19 -1.19044364607529
Escherichia coli M12  CO715_20570  ATI07907.1  212 aa transcriptional regulator 2.8e-31 ●●○○○ -1.19 -1.19023500006104
Acinetobacter baumannii ATCC 17978  A1S_2329  ABO12751.2  337 aa lipoate synthase 1.2e-5 ●●○○○ -1.19 -1.18996790263962
Escherichia coli M12  CO715_08440  ATI05737.1  243 aa arginine ABC transporter substrate-binding protein 3.4e-5 ●●○○○ -1.19 -1.18940041600404
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0039  WP_000971148.1  E8XG58  396 aa anaerobic sulfatase maturase 5.8e-7 ●●○○○ -1.19 -1.18933128346114
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3605  CBW19698.1  A0A0H3NMU0  lpfB  232 aa fimbrial chaperone protein (LpfB) 0.015 ●●○○○ -1.19 -1.18901397494984
Escherichia coli M12  CO715_06060  ATI05320.1  462 aa succinate-semialdehyde dehydrogenase 1.4e-47 ●●○○○ -1.19 -1.18898312397554
Escherichia coli M12  CO715_04985  ATI05144.1  468 aa phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) 3.2e-29 ●●○○○ -1.19 -1.18898312397554
Escherichia coli M12  CO715_21125  ATI08009.1  452 aa MFS transporter 7.5e-5 ●●○○○ -1.19 -1.18856583194705
Escherichia coli M12  CO715_12095  ATI06384.1  560 aa glycolate permease GlcA 2.2e-27 ●●○○○ -1.19 -1.1879398939043
Escherichia coli M12  CO715_00040  ATI04263.1  162 aa Fe-S cluster assembly transcriptional regulator IscR 0.0012 ●●○○○ -1.19 -1.1875226018758
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1946  WP_000002386.1  E8XA61  flhA  692 aa flagellar biosynthesis protein FlhA 0.048 ●●○○○ -1.19 -1.18751918199492
Escherichia coli M12  CO715_20240  ATI07846.1  152 aa DUF188 domain-containing protein 1.1e-18 ●●○○○ -1.19 -1.1871053098473
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4277  WP_000841337.1  E8XKG2  cytR  341 aa DNA-binding transcriptional regulator CytR 1.0e-6 ●●○○○ -1.19 -1.18698309548423
Escherichia coli CFT073  c2447  AAN80906.1  A0A0H2V8C7  cbl  316 aa Transcriptional regulator cbl 0.037 ●●○○○ -1.19 -1.18661712147746
Acinetobacter baumannii ATCC 17978  A1S_3104  ABO13501.1  615 aa putative ATP-dependent RNA helicase 2.9e-12 ●●○○○ -1.19 -1.18615507241811
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4561  WP_001232417.1  E8XAP0  hflC  334 aa protease modulator HflC 3.8e-7 ●●○○○ -1.19 -1.18572358331195
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2923  AIK81509.1  706 aa ABC transporter family protein 4.8e-13 ●●○○○ -1.18 -1.18425077907491
Escherichia coli M12  CO715_08495  ATI05748.1  377 aa polyamine ABC transporter ATP-binding protein 2.1e-95 ●●○○○ -1.18 -1.18334968159082
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3628  AIK82183.1  112 aa hypothetical protein 4.4e-16 ●●○○○ -1.18 -1.18305989625813
Escherichia coli M12  CO715_22305  ATI08223.1  127 aa autonomous glycyl radical cofactor GrcA 0.00056 ●●○○○ -1.18 -1.18272374354808
Escherichia coli M12  CO715_11515  ATI06278.1  119 aa DUF1889 domain-containing protein 2.2e-12 ●●○○○ -1.18 -1.18251509753383
Escherichia coli M12  CO715_08750  ATI05795.1  167 aa DNA starvation/stationary phase protection protein 1.0e-6 ●●○○○ -1.18 -1.18188915949108
Acinetobacter baumannii ATCC 17978  A1S_2440  ABO12858.1  A3M7G4  hflD  244 aa putative purine metabolism protein 0.0097 ●●○○○ -1.18 -1.18129870701596
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1707  AIK80327.1  219 aa transcriptional repressor 0.0074 ●●○○○ -1.18 -1.18110449420628
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1582  AIK80202.1  96 aa doxX family protein <1e-323 ●●○○○ -1.18 -1.18069691496491
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1098  AIK79721.1  214 aa hypothetical protein 0.0036 ●●○○○ -1.18 -1.18063714044282
Escherichia coli M12  CO715_24160  ATI08533.1  429 aa 16S rRNA m5C967 methyltransferase 1.5e-37 ●●○○○ -1.18 -1.18042863739134
Escherichia coli M12  CO715_01285  ATI04485.1  541 aa isovaleryl-CoA dehydrogenase 9.6e-24 ●●○○○ -1.18 -1.18021999137709
Escherichia coli M12  CO715_02920  ATI04780.1  289 aa N-acetylmuramoyl-L-alanine amidase AmiA 6.1e-17 ●●○○○ -1.18 -1.18021999137709
Escherichia coli M12  CO715_06110  ATI05328.1  96 aa autoinducer 2-degrading protein LsrG 4.2e-17 ●●○○○ -1.18 -1.17980269934859
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3976  AIK82525.1  176 aa cob(I)alamin adenosyltransferase <1e-323 ●●○○○ -1.18 -1.1797522784615
Escherichia coli M12  CO715_00410  ATI04329.1  136 aa type II toxin-antitoxin system HicB family antitoxin 3.6e-7 ●●○○○ -1.18 -1.17959405333435
Escherichia coli M12  CO715_07775  ATI05619.1  332 aa Fe3+ dicitrate ABC transporter permease 1.4e-6 ●●○○○ -1.18 -1.17917676130585
Escherichia coli M12  CO715_09450  ATI05917.1  254 aa alpha/beta hydrolase 3.4e-10 ●●○○○ -1.18 -1.1789681152916
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4838  AIK83365.1  224 aa nuoB <1e-323 ●●○○○ -1.18 -1.17883987700806
Escherichia coli M12  CO715_11830  ATI06334.1  131 aa antitoxin 0.048 ●●○○○ -1.18 -1.17834217724885
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4341  WP_010989089.1  E8XLA1  114 aa hypothetical protein 0.017 ●●○○○ -1.18 -1.17823297321504
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4052  WP_001519938.1  E8XIJ3  gidB  207 aa 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 0.00081 ●●○○○ -1.18 -1.17822171135597
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3200  WP_000194975.1  E8X9M4  gcvP  957 aa aminomethyl-transferring glycine dehydrogenase 2.2e-6 ●●○○○ -1.18 -1.17778566563341
Escherichia coli M12  CO715_15440  ATI06984.1  146 aa DUF805 domain-containing protein 0.00085 ●●○○○ -1.18 -1.17729894717761
Escherichia coli M12  CO715_10325  ATI06058.1  284 aa dimethyl sulfoxide reductase anchor subunit 1.6e-47 ●●○○○ -1.18 -1.17688165514911
Escherichia coli M12  CO715_24235  ATI08546.1  304 aa LysR family transcriptional regulator 6.1e-7 ●●○○○ -1.18 -1.17667300913486
Escherichia coli M12  CO715_03565  ATI04897.1  214 aa glutathione S-transferase 5.1e-5 ●●○○○ -1.18 -1.17646436312061
Escherichia coli M12  CO715_09080  ATI05857.1  239 aa nicotinamide riboside transporter PnuC 0.0074 ●●○○○ -1.18 -1.17646436312061
Escherichia coli M12  CO715_14195  ATI06755.1  296 aa iron-hydroxamate transporter substrate-binding subunit 1.3e-7 ●●○○○ -1.18 -1.17625571710636
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4698  WP_000484490.1  E8XCE0  yeeN  241 aa YebC/PmpR family DNA-binding transcriptional regulator 8.4e-6 ●●○○○ -1.18 -1.17539677117198
Porphyromonas gingivalis ATCC 33277  PGN_0080  WP_043876307.1  B2RGV4  83 aa hypothetical protein <1e-323 ●●○○○ -1.18 -1.17505334190739
Porphyromonas gingivalis ATCC 33277  PGN_0080  WP_012457224.1  B2RGV4  108 aa tetracycline resistance element mobilization regulatory protein RteC <1e-323 ●●○○○ -1.18 -1.17505334190739
Acinetobacter baumannii ATCC 17978  A1S_1566  ABO11993.2  198 aa putative 6-pyruvoyl-tetrahydropterin synthase 3.1e-8 ●●○○○ -1.17 -1.17492405398765
Escherichia coli M12  CO715_03900  ATI04958.1  239 aa DNA-binding response regulator 9.0e-71 ●●○○○ -1.17 -1.17437790297812
Escherichia coli M12  CO715_07635  ATI05598.1  308 aa peptide ABC transporter ATP-binding protein 9.4e-11 ●●○○○ -1.17 -1.17437790297812
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2591  WP_000331877.1  E8XGH9  nlpB  344 aa outer membrane protein assembly factor BamC 0.018 ●●○○○ -1.17 -1.17434893012261
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3810  WP_000220312.1  E8XFV3  lpfC  842 aa outer membrane usher protein LpfC 0.0072 ●●○○○ -1.17 -1.17393692503649
Escherichia coli M12  CO715_06970  ATI05478.1  71 aa holin 2.5e-40 ●●○○○ -1.17 -1.17354331892113
Escherichia coli M12  CO715_16815  ATI07234.1  142 aa hypothetical protein 0.00034 ●●○○○ -1.17 -1.17354331892113
Escherichia coli M12  CO715_20175  ATI07835.1  229 aa DNA-binding response regulator 0.0068 ●●○○○ -1.17 -1.17312602689263
Escherichia coli M12  CO715_21240  ATI08028.1  245 aa heme ABC transporter permease 3.8e-27 ●●○○○ -1.17 -1.17208279682139
Escherichia coli M12  CO715_15420  ATI06980.1  251 aa CDP-diacylglycerol pyrophosphatase 3.7e-19 ●●○○○ -1.17 -1.17187415080714
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4622  WP_000172704.1  E8XBH8  iolG  336 aa inositol 2-dehydrogenase IolG1 0.0045 ●●○○○ -1.17 -1.17111137465771
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4172  AIK82717.1  462 aa sugar (and other) transporter family protein 1.0e-6 ●●○○○ -1.17 -1.17085177785009
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2363  AIK80960.1  84 aa modulator of Rho-dependent transcription termination 1.8e-12 ●●○○○ -1.17 -1.17056165973334
Escherichia coli M12  CO715_19535  ATI07719.1  891 aa aconitate hydratase AcnA 1.4e-53 ●●○○○ -1.17 -1.1704136287074
Retrieved entries 3,601–3,700 out of 36,363 total in 439.3 ms (Link to these results)