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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Serratia marcescens Strain UMH9  BVG96_00530  ASL96187.1  479 aa serine endoprotease 0.0011 ●●●●○ -3.56 -3.56333666885775
Vibrio parahaemolyticus RIMD 2210633  VP_1052  BAC59315.1  Q87QU7  ruvB  334 aa holliday junction DNA helicase RuvB 0.00061 ●●●●○ -3.56 -3.56140423801191
Streptococcus pyogenes M1 5448  SP5448_00020  WP_010921763.1  371 aa redox-regulated ATPase YchF 0.00041 ●●●●○ -3.56 -3.55904427415492
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2293  NP_231924.1  P0C6E0  nqrC  257 aa Na(+)-translocating NADH-quinone reductase subunit C 1.3e-11 ●●●●○ -3.56 -3.55881086405241
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2122  WP_001000023.1  E8XBZ1  pduF  264 aa propanediol diffusion facilitator PduF 3.1e-22 ●●●●○ -3.56 -3.55632854308823
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3862  AIK82412.1  284 aa putative P-loop containing ATPase 4.8e-7 ●●●●○ -3.56 -3.5555567952866
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3967  WP_000350272.1  E8XHM7  rbsK  306 aa ribokinase 3.4e-25 ●●●●○ -3.55 -3.55473466078425
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1021  NP_230666.1  Q9KT84  luxO  455 aa LuxO repressor protein 9.8e-13 ●●●●○ -3.55 -3.55177181813874
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2288  CBW18390.1  A0A0H3NDU8  nuoK  100 aa NADH dehydrogenase I chain k 9.0e-14 ●●●●○ -3.55 -3.54642182826184
Acinetobacter baumannii ATCC 17978  A1S_0228  ABO10703.2  366 aa putative membrane protein 6.9e-11 ●●●●○ -3.54 -3.54465596511213
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3036  WP_000927219.1  E8XL24  inva  685 aa type III secretion system export apparatus protein InvA 1.5e-8 ●●●●○ -3.54 -3.5434803504728
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0839  NP_230487.1  P0C6D9  tcpJ  253 aa leader peptidase TcpJ 3.7e-8 ●●●●○ -3.54 -3.54167908309083
Acinetobacter baumannii ATCC 17978  A1S_0236  ABO10711.2  211 aa response regulator 1.8e-30 ●●●●○ -3.54 -3.54163799288447
Acinetobacter baumannii ATCC 17978  A1S_1144  ABO11574.2  263 aa merops peptidase family S24 6.4e-40 ●●●●○ -3.54 -3.53869933697145
Serratia marcescens Strain UMH9  BVG96_02675  ASL96571.1  180 aa replication initiation regulator SeqA 0.032 ●●●●○ -3.54 -3.53821391775542
Serratia marcescens Strain UMH9  BVG96_04570  ASL96920.1  457 aa phosphomannomutase/phosphoglucomutase 3.3e-6 ●●●●○ -3.54 -3.53730592947798
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4883  AIK83410.1  216 aa rcsB <1e-323 ●●●●○ -3.54 -3.53534473705801
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4777  WP_000876250.1  E8XDA5  stjB  802 aa fimbrial biogenesis outer membrane usher protein 9.1e-27 ●●●●○ -3.53 -3.53260880886723
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1353  CBW17449.1  A0A0H3NGA7  ssaR  215 aa Type III secretion system protein 8.1e-20 ●●●●○ -3.53 -3.53199970108495
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4664  WP_000410846.1  E8XBL9  arcA  406 aa arginine deiminase 2.0e-39 ●●●●○ -3.53 -3.5316277496139
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4295  CBW20381.1  A0A0H3NIR6  hfq  102 aa host factor-I protein(HF-I) 3.2e-13 ●●●●○ -3.53 -3.52737605720367
Vibrio parahaemolyticus RIMD 2210633  VP_1061  BAC59324.1  Q87QT8  pal  174 aa peptidoglycan-associated lipoprotein 0.00069 ●●●●○ -3.53 -3.52730671883994
Serratia marcescens Strain UMH9  BVG96_21650  ASM00064.1  260 aa hydrolase TatD 2.9e-5 ●●●●○ -3.52 -3.52429638744827
Vibrio parahaemolyticus RIMD 2210633  VP_1059  BAC59322.1  Q87QU0  356 aa TolA protein 0.00071 ●●●●○ -3.52 -3.51924444809933
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3978  AIK82526.1  117 aa hypothetical protein 1.9e-12 ●●●●○ -3.52 -3.518389219254
Vibrio parahaemolyticus RIMD 2210633  VP_0838  BAC59101.1  Q87RF9  seqA  180 aa SeqA protein 0.00073 ●●●●○ -3.51 -3.51019779729248
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0210  CBW16312.1  A0A0H3N9B4  htrA  475 aa protease DO precursor; heat shock protein HtrA 7.3e-10 ●●●●○ -3.51 -3.50883912349348
Haemophilus influenzae Rd KW20  HI_0286  NP_438453.1  P71348  alaA  404 aa aminotransferase AlaT 0.00073 ●●●●○ -3.5 -3.50326736970956
Vibrio parahaemolyticus RIMD 2210633  VPA_1192  BAC62535.1  Q87GX3  154 aa putative deoxycytidylate deaminase 0.0011 ●●●●○ -3.5 -3.49838228081622
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1496  NP_231137.1  Q9KRY7  665 aa carboxy-terminal protease 9.0e-12 ●●●●○ -3.49 -3.49475250463704
Acinetobacter baumannii ATCC 17978  A1S_0218  ABO10693.2  112 aa nitrogen assimilation regulatory protein P-II 2 2.0e-10 ●●●●○ -3.49 -3.4903409723282
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3473  WP_000531566.1  E8XCD0  yrbF  270 aa phospholipid ABC transporter ATP-binding protein MlaF 6.3e-26 ●●●●○ -3.49 -3.49028601024745
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0741  WP_001194239.1  E8XAV2  246 aa hypothetical protein 1.7e-26 ●●●●○ -3.49 -3.48606936061612
Vibrio parahaemolyticus RIMD 2210633  VP_0194  BAC58457.1  Q87T76  351 aa putative lipopolysaccharide biosynthesis protein 0.0008 ●●●●○ -3.48 -3.48488975534238
Vibrio parahaemolyticus RIMD 2210633  VP_2731  BAC60994.1  Q87L81  pgi  550 aa glucose-6-phosphate isomerase 0.00081 ●●●●○ -3.48 -3.48341725852809
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2237  WP_000945364.1  E8XCZ0  stcC  829 aa fimbrial biogenesis outer membrane usher protein 4.7e-23 ●●●●○ -3.48 -3.48307329584481
Serratia marcescens Strain UMH9  BVG96_15180  ASL98890.1  112 aa outer membrane protein assembly factor BamE 8.6e-5 ●●●●○ -3.48 -3.47696792133539
Acinetobacter baumannii ATCC 17978  A1S_2952  ABO13357.2  467 aa putative pyridine nucleotide-disulfide oxidoreductase class I 3.5e-27 ●●●●○ -3.47 -3.47376872621831
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3931  CBW20022.1  A0A0H3NJR3  rfaH  162 aa transcriptional activator 2.0e-10 ●●●●○ -3.47 -3.47174769962056
Acinetobacter baumannii ATCC 17978  A1S_1575  ABO12002.2  A3M508  pyrF  232 aa orotidine-5'-phosphate decarboxylase 2.4e-33 ●●●●○ -3.47 -3.47112231195409
Vibrio parahaemolyticus RIMD 2210633  VP_1060  BAC59323.1  Q87QT9  tolB  450 aa TolB protein 0.00085 ●●●●○ -3.47 -3.46694379365467
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2378  WP_000858952.1  E8XEC4  glpQ  356 aa glycerophosphodiester phosphodiesterase 2.3e-7 ●●●●○ -3.45 -3.45462528832111
Vibrio parahaemolyticus RIMD 2210633  VP_2285  BAC60548.1  Q87MH0  purM  346 aa phosphoribosylformylglycinamidine cyclo-ligase 0.0009 ●●●●○ -3.45 -3.45096609384476
Vibrio parahaemolyticus RIMD 2210633  VP_2577  BAC60840.1  Q87LN4  212 aa sigma-E factor negative regulatory protein RseA 0.00091 ●●●●○ -3.45 -3.44898205230677
Serratia marcescens Strain UMH9  BVG96_04550  ASL96916.1  444 aa hypothetical protein 2.7e-5 ●●●●○ -3.45 -3.44882948913746
Streptococcus pyogenes M1 5448  SP5448_04070  WP_002989295.1  419 aa UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.00074 ●●●●○ -3.45 -3.44849057687746
Streptococcus pyogenes M1 5448  SP5448_06590  WP_011285473.1  222 aa ABC transporter ATP-binding protein 0.00085 ●●●●○ -3.45 -3.4475292403794
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4344  WP_001526923.1  E8XLA4  62 aa hypothetical protein 7.0e-27 ●●●●○ -3.44 -3.44486344178355
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3150  WP_000564481.1  E8X8T7  ygdP  176 aa RNA pyrophosphohydrolase 2.1e-25 ●●●●○ -3.44 -3.44371581077506
Vibrio parahaemolyticus RIMD 2210633  VP_0509  BAC58772.1  Q87SB5  xerD  305 aa integrase/recombinase XerD 0.00095 ●●●●○ -3.44 -3.43592116492073
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2215  AIK80820.1  431 aa phosphate regulon sensor kinase PhoR <1e-323 ●●●●○ -3.43 -3.43438178987804
Haemophilus influenzae Rd KW20  HI_0039  NP_438212.1  P44476  mreD  162 aa rod shape-determining protein MreD 0.00092 ●●●●○ -3.43 -3.43431004284706
Vibrio parahaemolyticus RIMD 2210633  VP_0121  BAC58384.1  Q87TE8  469 aa glutamate-ammonia ligase 0.00098 ●●●●○ -3.43 -3.42567300738003
Acinetobacter baumannii ATCC 17978  A1S_3025  ABO13422.2  A3M928  mdh  328 aa malate dehydrogenase 5.1e-24 ●●●●○ -3.43 -3.42527743474369
Acinetobacter baumannii ATCC 17978  A1S_2585  ABO13002.2  1277 aa phosphoribosylformylglycinamidine synthase 7.3e-15 ●●●●○ -3.42 -3.42419568212477
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2026  NP_231660.1  Q9KQH2  174 aa hypothetical protein 1.7e-6 ●●●●○ -3.42 -3.42330255057261
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2469  WP_000699178.1  E8XF25  pdxB  378 aa 4-phosphoerythronate dehydrogenase PdxB 4.6e-7 ●●●●○ -3.42 -3.42244555998346
Acinetobacter baumannii ATCC 17978  A1S_0418  ABO10873.1  A3M1S9  leuD  215 aa 3-isopropylmalate isomerase (dehydratase) subunit with LeuC 7.8e-50 ●●●●○ -3.42 -3.42047630797008
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1539  WP_000513122.1  E8XIX5  180 aa nuclear transport factor 2 family protein 3.1e-24 ●●●●○ -3.42 -3.41626928195957
Acinetobacter baumannii ATCC 17978  A1S_2768  ABO13180.2  A3M8D6  uppP  272 aa bacitracin resistance protein 4.3e-43 ●●●●○ -3.41 -3.41457909880922
Haemophilus influenzae Rd KW20  HI_0138  NP_438307.1  P43807  rnhA  154 aa ribonuclease H 0.00099 ●●●●○ -3.41 -3.41427747333741
Vibrio parahaemolyticus RIMD 2210633  VP_2202  BAC60465.1  Q87MM9  aroC  361 aa chorismate synthase 0.001 ●●●●○ -3.41 -3.40831963087326
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0803  WP_000096928.1  E8XB08  modf  491 aa molybdate ABC transporter ATP-binding protein ModF 1.1e-26 ●●●●○ -3.41 -3.40748607051422
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1567  WP_000201080.1  E8XJ02  335 aa LacI family DNA-binding transcriptional regulator 6.5e-7 ●●●●○ -3.41 -3.40582209110901
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2614  NP_232242.1  Q9KNW6  210 aa cAMP-regulatory protein 2.1e-6 ●●●●○ -3.4 -3.40192525143486
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3482  WP_000609332.1  E8XD25  ptsN  163 aa PTS IIA-like nitrogen regulatory protein PtsN 2.6e-8 ●●●●○ -3.4 -3.40118018763437
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0419  NP_232813.1  Q9KME2  261 aa hypothetical protein 1.2e-8 ●●●●○ -3.39 -3.39168323609424
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2293  CBW18395.1  A0A0H3NDV2  nuoF  445 aa NADH dehydrogenase I chain F 2.0e-12 ●●●●○ -3.39 -3.39056311338035
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2063  CBW18159.1  A0A0H3NIL6  rfbU  353 aa glycosyltransferase 3.7e-10 ●●●●○ -3.39 -3.38863145902885
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2857  WP_001528723.1  E8XJ82  64 aa DUF2724 domain-containing protein 3.0e-9 ●●●●○ -3.39 -3.38800213617425
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2857  WP_000963476.1  E8XJ82  113 aa hypothetical protein 3.0e-9 ●●●●○ -3.39 -3.38800213617425
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2369  WP_000705579.1  E8XEB5  400 aa mandelate racemase/muconate lactonizing enzyme family protein 1.1e-23 ●●●●○ -3.39 -3.38704458006662
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2436  NP_232066.1  Q9K2Y1  tolC  438 aa outer membrane channel protein 2.3e-13 ●●●●○ -3.38 -3.3828572813204
Acinetobacter baumannii ATCC 17978  A1S_0420  ABO10875.2  359 aa 3-isopropylmalate dehydrogenase 4.2e-48 ●●●●○ -3.38 -3.38086579693942
Streptococcus pyogenes M1 5448  SP5448_06600  WP_002990406.1  128 aa DUF1722 domain-containing protein 0.00012 ●●●●○ -3.38 -3.3792743490168
Streptococcus pyogenes M1 5448  SP5448_08860  WP_002991275.1  326 aa sugar-binding transcriptional regulator 0.0011 ●●●●○ -3.38 -3.37831301251873
Vibrio parahaemolyticus RIMD 2210633  VP_2193  BAC60456.1  Q87MN8  pdxB  377 aa erythronate-4-phosphate dehydrogenase 0.0012 ●●●●○ -3.37 -3.37413446864485
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0237  NP_229894.1  H9L4P0  399 aa hypothetical protein 2.5e-13 ●●●●○ -3.37 -3.37117700669953
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0288  WP_001541860.1  E8XIU1  51 aa hypothetical protein 1.4e-6 ●●●●○ -3.37 -3.36890759128355
Serratia marcescens Strain UMH9  BVG96_11095  ASL98133.1  136 aa flagellar protein FliS 6.9e-5 ●●●●○ -3.37 -3.36752506200158
Vibrio parahaemolyticus RIMD 2210633  VP_0666  BAC58929.1  Q87RW0  purL  1302 aa phosphoribosylformylglycinamidine synthase 0.0012 ●●●●○ -3.37 -3.36581174339158
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1552  WP_001518759.1  E8XIY8  263 aa FadR family transcriptional regulator 1.6e-6 ●●●●○ -3.36 -3.36130130539017
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3613  AIK82168.1  397 aa flavo, HI0933 family protein 3.7e-9 ●●●●○ -3.36 -3.36106694856597
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2414  NP_232044.1  Q9KPF4  886 aa pyruvate dehydrogenase subunit E1 2.7e-13 ●●●●○ -3.36 -3.36037224155209
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1431  WP_002860363.1  Q29VV3  566 aa hypothetical protein 0.00074 ●●●●○ -3.36 -3.35720902645
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2067  NP_231699.1  Q9KQD3  313 aa MinD-like protein 1.4e-8 ●●●●○ -3.35 -3.35307785052905
Mycobacterium avium subsp. paratuberculosis K10  MAP_0686  AAS03003.1  Q742Z9  389 aa hypothetical protein 0.00048 ●●●●○ -3.35 -3.35097402543567
Vibrio parahaemolyticus RIMD 2210633  VP_1040  BAC59303.1  Q87QV9  322 aa hypothetical protein 0.0013 ●●●●○ -3.35 -3.35096412430834
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4273  WP_000139639.1  E8XKF8  menA  309 aa 1,4-dihydroxy-2-naphthoate polyprenyltransferase 2.9e-8 ●●●●○ -3.35 -3.35035758994379
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1726  NP_231362.1  Q9KRB6  glgA  484 aa glycogen synthase 6.6e-9 ●●●●○ -3.35 -3.34956188924918
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2332  CBW18434.1  A0A0H3NJT2  cvpA  162 aa colicin V production protein (DedE protein) 2.5e-12 ●●●●○ -3.35 -3.34839566625773
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3396  WP_001001853.1  E8XC59  tdcD  402 aa propionate kinase 5.7e-23 ●●●●○ -3.35 -3.34792159363704
Vibrio parahaemolyticus RIMD 2210633  VP_2831  BAC61094.1  Q87KZ3  secB  154 aa protein-transport protein SecB 0.0013 ●●●●○ -3.34 -3.34438622182295
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0083  NP_229742.1  Q9KVQ6  ubiE  260 aa ubiquinone/menaquinone biosynthesis methyltransferase 4.1e-13 ●●●●○ -3.34 -3.3442734261983
Acinetobacter baumannii ATCC 17978  A1S_2687  ABO13100.2  1076 aa carbamoyl-phosphate synthase large subunit 1.6e-29 ●●●●○ -3.34 -3.34312538008961
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3095  CBW19194.1  A0A0H3NHU1  242 aa hypothetical LysR-family transcriptional regulator 5.8e-14 ●●●●○ -3.34 -3.33903126622674
Serratia marcescens Strain UMH9  BVG96_21205  ASL99980.1  376 aa UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) 0.00096 ●●●●○ -3.34 -3.33821379149441
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1895  NP_231529.1  Q9KQV3  129 aa hypothetical protein 1.5e-11 ●●●●○ -3.34 -3.33606574026407
Vibrio parahaemolyticus RIMD 2210633  VP_0142  BAC58405.1  Q87TC8  164 aa general secretion pathway protein M 0.0013 ●●●●○ -3.34 -3.33598212144806
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2296  CBW18398.1  A0A0H3NDQ5  nuoB  220 aa NADH dehydrogenase I chain B 2.1e-13 ●●●●○ -3.33 -3.3345619795647
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