Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4157  AIK82703.1  88 aa flavinator of succinate dehydrogenase family protein 5.5e-10 ●●●○○ -2.72 -2.71907240619755
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2914  WP_001738474.1  E8XK20  pipB2  350 aa SPI-2 type III secretion system effector PipB2 4.0e-10 ●●●○○ -2.72 -2.71843438373103
Streptococcus pyogenes M1 5448  SP5448_01150  WP_002986111.1  148 aa dUTP diphosphatase 0.018 ●●●○○ -2.71 -2.71402949235596
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0093  CBW16195.1  A0A0H3NH51  surA  428 aa survival protein SurA precursor 7.3e-10 ●●●○○ -2.71 -2.71391446372748
Streptococcus pyogenes M1 5448  SP5448_02745  WP_002983603.1  247 aa amino acid ABC transporter ATP-binding protein 0.016 ●●●○○ -2.71 -2.71306815585789
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4202  AIK82747.1  211 aa bacterial regulatory, luxR family protein 1.5e-10 ●●●○○ -2.71 -2.71288497383065
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0717  CBW16815.1  A0A0H3N9N1  sdhB  239 aa succinate dehydrogenase iron-sulfur protein 9.1e-6 ●●●○○ -2.71 -2.7121725341282
Haemophilus influenzae Rd KW20  HI_1702  NP_439844.1  P45331  metE  756 aa 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.0085 ●●●○○ -2.71 -2.70996642668883
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0763  NP_230412.1  Q9KTW7  der  494 aa GTP-binding protein EngA 2.0e-11 ●●●○○ -2.71 -2.70881113397556
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2517  CBW18618.1  A0A0H3NPT7  glyA  417 aa serine hydroxymethyltransferase 2.8e-8 ●●●○○ -2.7 -2.70340635859345
Acinetobacter baumannii ATCC 17978  A1S_0979  ABO11411.2  A3M3B7  nfuA  212 aa putative membrane-bound protein in GNT I transport system (GntY) 3.6e-21 ●●●○○ -2.7 -2.70039669709188
Acinetobacter baumannii ATCC 17978  A1S_0326  ABO10790.2  198 aa dephosphocoenzyme A kinase 5.3e-5 ●●●○○ -2.7 -2.69719872073768
Vibrio parahaemolyticus RIMD 2210633  VP_0520  BAC58783.1  Q87SA4  rppH  174 aa MutT/nudix family protein 0.0092 ●●●○○ -2.7 -2.69660867190421
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0584  WP_009882282.1  A0A0H3PAG1  311 aa pyridine nucleotide-disulfide oxidoreductase 0.0055 ●●●○○ -2.69 -2.69220893509
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0101  WP_002851985.1  A0A0H3PCJ0  288 aa MinD/ParA family protein 0.0056 ●●●○○ -2.69 -2.68721234811
Vibrio parahaemolyticus RIMD 2210633  VPA_1372  BAC62715.1  Q87GE4  36 aa hypothetical protein 0.013 ●●●○○ -2.69 -2.68592683473276
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0065  CBW16166.1  A0A0H3NH29  dapB  273 aa dihydrodipicolinate reductase 4.3e-7 ●●●○○ -2.68 -2.68463754155589
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2234  NP_231865.1  Q9KPX8  rnhA  156 aa ribonuclease H 1.1e-14 ●●●○○ -2.68 -2.68437889087073
Escherichia coli M12  CO715_09170  ATI05866.1  97 aa cyd operon protein YbgE 6.6e-6 ●●●○○ -2.68 -2.68330587802589
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1753  CBW17848.1  A0A0H3NDP6  pabB  454 aa para-aminobenzoate synthase component I 7.1e-6 ●●●○○ -2.68 -2.68234969921322
Vibrio parahaemolyticus RIMD 2210633  VPA_0517  BAC61860.1  Q87IT9  427 aa conserved hypothetical protein 0.013 ●●●○○ -2.68 -2.68218047671461
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1698  NP_231334.1  Q9KRE4  215 aa hypothetical protein 2.5e-12 ●●●○○ -2.68 -2.68187912076284
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1914  NP_231548.1  Q9KQT4  ihfB  92 aa integration host factor subunit beta 2.0e-12 ●●●○○ -2.68 -2.67979879483475
Streptococcus pyogenes M1 5448  SP5448_03075  WP_010922518.1  251 aa class I SAM-dependent methyltransferase 0.017 ●●●○○ -2.68 -2.67942137842562
Vibrio parahaemolyticus RIMD 2210633  VP_0575  BAC58838.1  Q87S49  557 aa phosphate ABC transporter, permease protein 0.0096 ●●●○○ -2.68 -2.67917635212084
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3181  AIK81749.1  448 aa wzyE family protein <1e-323 ●●●○○ -2.68 -2.67894636091956
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0673  WP_001044182.1  E8XA11  642 aa sigma-54-dependent transcriptional regulator 2.4e-20 ●●●○○ -2.68 -2.67874848247288
Acinetobacter baumannii ATCC 17978  A1S_0737  ABO11177.2  347 aa 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase 2.2e-24 ●●●○○ -2.68 -2.6773453677468
Streptococcus pyogenes M1 5448  SP5448_07570  WP_010921970.1  158 aa NUDIX domain-containing protein 0.017 ●●●○○ -2.68 -2.67653736893143
Vibrio parahaemolyticus RIMD 2210633  VP_3067  BAC61330.1  Q87KB0  glmU  453 aa UDP-N-acetylglucosamine pyrophosphorylase 0.0097 ●●●○○ -2.68 -2.6754892050711
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0869  NP_230516.1  Q9KTN2  purL  1297 aa phosphoribosylformylglycinamidine synthase 1.5e-11 ●●●○○ -2.68 -2.67543152890975
Acinetobacter baumannii ATCC 17978  A1S_0826  ABO11264.1  95 aa peptidyl-tRNA hydrolase 2.0e-12 ●●●○○ -2.68 -2.67542519829409
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4081  WP_000208528.1  E8XIL4  ilvE  309 aa branched-chain-amino-acid transaminase 6.7e-7 ●●●○○ -2.67 -2.67362079175362
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1069  WP_000847719.1  E8XE34  ycct  220 aa DUF2057 family protein 0.0022 ●●●○○ -2.67 -2.67310375941941
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1500  WP_002869208.1  A0A0H3PAD3  fdhD  260 aa formate dehydrogenase accessory sulfurtransferase FdhD 0.0058 ●●●○○ -2.67 -2.67303439367
Streptococcus pyogenes M1 5448  SP5448_00850  WP_010921826.1  292 aa hypothetical protein 0.011 ●●●○○ -2.67 -2.67076934994304
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0648  WP_000958610.1  E8X9Y6  dcuC  461 aa anaerobic C4-dicarboxylate transporter DcuC 1.6e-5 ●●●○○ -2.67 -2.66969048343188
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3269  WP_001112898.1  E8XAG9  cilB  280 aa CoA ester lyase 4.1e-30 ●●●○○ -2.67 -2.66861771787241
Mycobacterium avium subsp. paratuberculosis K10  MAP_2252c  AAS04569.1  Q73XQ7  257 aa hypothetical protein 0.0037 ●●●○○ -2.67 -2.66737748612658
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2179  WP_000973708.1  E8XC48  rfbC  183 aa dTDP-4-dehydrorhamnose 3,5-epimerase 9.0e-18 ●●●○○ -2.67 -2.66706286362776
Serratia marcescens Strain UMH9  BVG96_20130  ASL99788.1  55 aa 50S ribosomal protein L33 0.004 ●●●○○ -2.67 -2.66596750123719
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2070  CBW18166.1  A0A0H3NN86  rfbI  330 aa reductase 1.1e-6 ●●●○○ -2.67 -2.66502045826822
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0487  NP_232879.1  Q9KM94  177 aa hypothetical protein 3.4e-9 ●●●○○ -2.66 -2.66482596134474
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4708  WP_000841654.1  E8XCF0  257 aa Uxu operon transcriptional regulator 3.6e-18 ●●●○○ -2.66 -2.66456737566505
Mycobacterium avium subsp. paratuberculosis K10  MAP_1070c  AAS03387.1  Q741M0  887 aa hypothetical protein 0.0038 ●●●○○ -2.66 -2.66384669227912
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4010  WP_000061259.1  E8XHR9  420 aa MFS transporter 3.7e-18 ●●●○○ -2.66 -2.66377161102056
Vibrio parahaemolyticus RIMD 2210633  VP_2945  BAC61208.1  Q87KN2  lexA  206 aa LexA repressor 0.01 ●●●○○ -2.66 -2.66111903826719
Vibrio parahaemolyticus RIMD 2210633  VP_0234  BAC58497.1  Q87T36  391 aa pilin glycosylation protein 0.01 ●●●○○ -2.66 -2.65914734551097
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4981  AIK83507.1  333 aa helix-turn-helix family protein <1e-323 ●●●○○ -2.65 -2.65355982585037
Acinetobacter baumannii ATCC 17978  A1S_2710  ABO13123.2  424 aa hypothetical protein 3.5e-23 ●●●○○ -2.65 -2.65322502181965
Haemophilus influenzae Rd KW20  HI_1740  NP_439884.1  P43809  recG  693 aa ATP-dependent DNA helicase RecG 0.01 ●●●○○ -2.65 -2.65243969570963
Haemophilus influenzae Rd KW20  HI_0856  NP_439016.1  P43741  polA  930 aa DNA polymerase I 0.01 ●●●○○ -2.65 -2.65243969570963
Acinetobacter baumannii ATCC 17978  A1S_2446  ABO12864.2  465 aa high-affinity phosphate transport protein 8.2e-33 ●●●○○ -2.65 -2.65118301650273
Vibrio parahaemolyticus RIMD 2210633  VPA_1368  BAC62711.1  Q87GE8  85 aa hypothetical protein 0.015 ●●●○○ -2.65 -2.65004102163003
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0152  NP_232552.1  Q9KN14  107 aa monovalent cation/H+ antiporter subunit G 5.6e-8 ●●●○○ -2.65 -2.64845397891013
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0248  NP_232646.1  Q9KMS2  355 aa L-ascorbate 6-phosphate lactonase 6.4e-8 ●●●○○ -2.65 -2.64763422047122
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0724  NP_233111.1  Q9KLL9  modC  366 aa molybdate transporter ATP-binding protein 6.0e-8 ●●●○○ -2.64 -2.64497704522197
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1574  NP_231214.1  Q9KRR2  127 aa hypothetical protein 2.3e-10 ●●●○○ -2.64 -2.64142945979305
Streptococcus pyogenes M1 5448  SP5448_01955  WP_002988556.1  234 aa ABC transporter permease 0.012 ●●●○○ -2.64 -2.6390452455069
Serratia marcescens Strain UMH9  BVG96_14880  ASL98833.1  173 aa co-chaperone HscB 0.0042 ●●●○○ -2.64 -2.63662303181163
Streptococcus pyogenes M1 5448  SP5448_05865  WP_002990002.1  393 aa AI-2E family transporter 8.1e-5 ●●●○○ -2.64 -2.63616123601271
Haemophilus influenzae Rd KW20  HI_0896  NP_439057.1  Q57434  204 aa cell division protein 0.01 ●●●○○ -2.64 -2.63548916958549
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0700  NP_233087.1  Q9KLP3  1051 aa chitodextrinase 4.0e-13 ●●●○○ -2.63 -2.63438064745133
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4184  WP_000146194.1  E8XJI8  glnL  349 aa nitrogen regulation protein NR(II) 9.3e-7 ●●●○○ -2.63 -2.63432441444726
Streptococcus pyogenes M1 5448  SP5448_03540  WP_002985390.1  79 aa hypothetical protein 0.012 ●●●○○ -2.63 -2.63423856301658
Vibrio parahaemolyticus RIMD 2210633  VP_1035  BAC59298.1  Q87QW4  mukF  445 aa MukF protein 0.011 ●●●○○ -2.63 -2.63340751936315
Vibrio parahaemolyticus RIMD 2210633  VPA_0864  BAC62207.1  Q87HU2  568 aa putative ABC transporter periplasmic solute binding protein 0.015 ●●●○○ -2.63 -2.63227920882495
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2457  WP_000072512.1  E8XF13  473 aa amino acid permease 9.3e-21 ●●●○○ -2.63 -2.63179048057701
Acinetobacter baumannii ATCC 17978  A1S_3118  ABO13515.2  325 aa glycyl-tRNA synthetase alpha chain 3.7e-12 ●●●○○ -2.63 -2.62994200016358
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0712  CBW16810.1  A0A0H3N9M7  gltA  427 aa citrate synthase 5.9e-7 ●●●○○ -2.63 -2.62975376480003
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4034  WP_000212197.1  E8XHU3  pstA  296 aa phosphate ABC transporter permease PstA 1.2e-6 ●●●○○ -2.63 -2.62778431127994
Serratia marcescens Strain UMH9  BVG96_16890  ASL99194.1  887 aa pyruvate dehydrogenase (acetyl-transferring), homodimeric type 0.0059 ●●●○○ -2.63 -2.62671853897993
Streptococcus pyogenes M1 5448  SP5448_06990  WP_002985511.1  77 aa hypothetical protein 0.015 ●●●○○ -2.63 -2.625586534534
Vibrio parahaemolyticus RIMD 2210633  VP_2896  BAC61159.1  Q87KT0  purH  530 aa phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.011 ●●●○○ -2.63 -2.62549523142247
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3280  WP_000338754.1  E8XAI0  161 aa Hcp1 family type VI secretion system effector 1.0e-20 ●●●○○ -2.63 -2.62507347129155
Mycobacterium avium subsp. paratuberculosis K10  MAP_3448  AAS05998.1  Q73UC0  394 aa hypothetical protein 0.0042 ●●●○○ -2.62 -2.62313573276385
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3746  WP_000187489.1  E8XF91  yhhQ  221 aa 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter 8.5e-17 ●●●○○ -2.62 -2.62297522845191
Acinetobacter baumannii ATCC 17978  A1S_0059  ABO10554.2  344 aa putative glycosyltransferase 1.6e-5 ●●●○○ -2.62 -2.6226619692432
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0610  NP_232999.1  Q9KLY1  216 aa isoprenoid biosynthesis protein 1.8e-9 ●●●○○ -2.62 -2.62035747219933
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1300  WP_002855735.1  A0A0H3PE22  447 aa potassium transporter 0.0067 ●●●○○ -2.62 -2.61912212886
Serratia marcescens Strain UMH9  BVG96_21185  ASL99976.1  108 aa thiol reductase thioredoxin 0.0053 ●●●○○ -2.62 -2.61800591880503
Serratia marcescens Strain UMH9  BVG96_17805  ASL99363.1  284 aa RNase adaptor protein RapZ 0.01 ●●●○○ -2.62 -2.61546443104675
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3199  WP_000819369.1  E8X9M3  297 aa transporter 9.8e-7 ●●●○○ -2.61 -2.61495690423627
Acinetobacter baumannii ATCC 17978  A1S_3066  ABO13463.2  A3M969  rplF  177 aa 50S ribosomal protein L6 0.00025 ●●●○○ -2.61 -2.6140972412087
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1564  AIK80184.1  164 aa lrp transcriptional dual regulator 5.5e-10 ●●●○○ -2.61 -2.60910664048036
Acinetobacter baumannii ATCC 17978  A1S_0835  ABO11269.1  192 aa outer-membrane lipoprotein precursor 3.9e-10 ●●●○○ -2.61 -2.60904132184974
Haemophilus influenzae Rd KW20  HI_0639  NP_438799.1  P44797  purB  456 aa adenylosuccinate lyase 0.011 ●●●○○ -2.61 -2.60742868689522
Vibrio parahaemolyticus RIMD 2210633  VP_2741  BAC61004.1  Q87L71  223 aa ribulose-phosphate 3-epimerase 0.012 ●●●○○ -2.61 -2.60703243247293
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4176  AIK82721.1  65 aa virulence Q domain protein 0.0077 ●●●○○ -2.61 -2.60610573815763
Streptococcus pyogenes M1 5448  SP5448_08530  WP_010922683.1  249 aa isoprenyl transferase 0.011 ●●●○○ -2.6 -2.60443713157657
Vibrio parahaemolyticus RIMD 2210633  VP_2838  BAC61101.1  Q87KY6  epmA  323 aa lysyl-tRNA synthetase-related protein 0.012 ●●●○○ -2.6 -2.60261561367051
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2541  NP_232169.1  Q9KP38  ubiX  211 aa aromatic acid decarboxylase 5.8e-11 ●●●○○ -2.6 -2.59899067145847
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1193  AIK79816.1  520 aa anthranilate synthase component I 0.0016 ●●●○○ -2.6 -2.59844744322448
Acinetobacter baumannii ATCC 17978  A1S_1179  ABO11609.2  439 aa adenylosuccinate synthetase 4.1e-5 ●●●○○ -2.6 -2.59804978523795
Streptococcus pyogenes M1 5448  SP5448_05120  WP_010922322.1  376 aa sodium ion-translocating decarboxylase subunit beta 0.0065 ●●●○○ -2.6 -2.59674643959205
Escherichia coli CFT073  c1859  AAN80322.1  A0A0H2V8F8  ydcP  667 aa Putative protease ydcP precursor 0.024 ●●●○○ -2.6 -2.59613185008052
Streptococcus pyogenes M1 5448  SP5448_03185  WP_011285644.1  577 aa sensor histidine kinase 0.014 ●●●○○ -2.6 -2.59578510309399
Acinetobacter baumannii ATCC 17978  A1S_0127  ABO10612.2  213 aa putative integral membrane protein (DedA) 1.5e-5 ●●●○○ -2.59 -2.59266270215728
Streptococcus pyogenes M1 5448  SP5448_06665  WP_010922117.1  164 aa F0F1 ATP synthase subunit B 0.0047 ●●●○○ -2.59 -2.59193975710173
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2413  NP_232043.1  Q9KPF5  635 aa dihydrolipoamide acetyltransferase 8.8e-10 ●●●○○ -2.59 -2.59164476751619
Retrieved entries 1,001–1,100 out of 36,363 total in 6.1 ms (Link to these results)