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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2724  NP_232351.1  P41851  epsM  166 aa cholera toxin secretion protein EpsM 9.6e-11 ●●●○○ -2.27 -2.27349222326896
Vibrio parahaemolyticus RIMD 2210633  VPA_1322  BAC62665.1  Q87GJ4  98 aa putative zinc finger protein 0.037 ●●●○○ -2.27 -2.27160134604951
Escherichia coli M12  CO715_15535  ATI06998.1  105 aa met repressor 3.6e-14 ●●●○○ -2.27 -2.27060406184164
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1080  NP_230725.1  Q9KT25  121 aa hypothetical protein 3.8e-8 ●●●○○ -2.27 -2.2703360841789
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1127  NP_230772.1  Q9KSX9  hflD  205 aa hypothetical protein 1.8e-8 ●●●○○ -2.27 -2.2682801862215
Vibrio parahaemolyticus RIMD 2210633  VP_1036  BAC59299.1  Q87QW3  mukE  248 aa MukE protein 0.027 ●●●○○ -2.27 -2.26805256700272
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0962  NP_233346.1  Q9KKY8  402 aa hypothetical protein 6.2e-9 ●●●○○ -2.27 -2.26665444463719
Streptococcus pyogenes M1 5448  SP5448_05000  WP_002989733.1  185 aa membrane protein 0.029 ●●●○○ -2.27 -2.26508534775969
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4254  AIK82799.1  392 aa acetyl-CoA C-acetyltransferase family protein 7.1e-7 ●●●○○ -2.26 -2.26435629177333
Mycobacterium avium subsp. paratuberculosis K10  MAP_0900  AAS03217.1  Q04959  298 aa hypothetical protein 0.01 ●●●○○ -2.26 -2.26350988151121
Acinetobacter baumannii ATCC 17978  A1S_0545  ABO10998.2  A3M254  ilvC  338 aa acetohydroxy acid isomeroreductase 9.4e-36 ●●●○○ -2.26 -2.26244515492444
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2511  WP_001112946.1  E8XFM3  yfeA  729 aa sensor domain-containing phosphodiesterase 1.5e-5 ●●●○○ -2.26 -2.2622490561586
Acinetobacter baumannii ATCC 17978  A1S_0439  ABO10894.2  878 aa DNA topoisomerase type I omega protein 4.3e-11 ●●●○○ -2.26 -2.26180738070448
Haemophilus influenzae Rd KW20  HI_1146  NP_439304.2  P45071  285 aa hypothetical protein 0.026 ●●●○○ -2.26 -2.2609561686427
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1763  NP_231398.1  Q9KR80  244 aa chemotaxis protein MotB-like protein 4.8e-11 ●●●○○ -2.26 -2.26001823827481
Haemophilus influenzae Rd KW20  HI_1277  NP_439430.2  P45135  mrp  370 aa ATPase 0.026 ●●●○○ -2.26 -2.25970995479329
Mycobacterium avium subsp. paratuberculosis K10  MAP_4254  AAS06804.1  Q73S22  299 aa hypothetical protein 0.01 ●●●○○ -2.26 -2.25910385617472
Acinetobacter baumannii ATCC 17978  A1S_1710  ABO12137.2  263 aa putative membrane protein 4.3e-37 ●●●○○ -2.26 -2.25899370638008
Mycobacterium avium subsp. paratuberculosis K10  MAP_1090  AAS03407.1  Q741K0  dppD  535 aa DppD_2 0.01 ●●●○○ -2.26 -2.25551182951984
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1348  WP_000562009.1  E8XGF0  cdgr  237 aa anti-FlhDC factor YdiV 2.5e-17 ●●●○○ -2.26 -2.25530328717998
Acinetobacter baumannii ATCC 17978  A1S_0004  ABO10501.2  822 aa DNA gyrase 4.1e-10 ●●●○○ -2.26 -2.25528896830291
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1004  NP_230650.1  Q9KT99  purF  504 aa amidophosphoribosyltransferase 3.8e-13 ●●●○○ -2.25 -2.25369019399535
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1232  WP_002868857.1  A0A0H3PCX2  846 aa hypothetical protein 0.016 ●●●○○ -2.25 -2.25348244801
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0351  WP_001247039.1  E8XJN5  stbE  252 aa fimbrial assembly chaperone 2.7e-17 ●●●○○ -2.25 -2.25320758586659
Vibrio parahaemolyticus RIMD 2210633  VP_1105  BAC59368.1  Q87QP4  ftsK  1028 aa putative cell division protein FtsK 0.027 ●●●○○ -2.25 -2.25250949319165
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2680  WP_001022463.1  E8XHF3  308 aa LysR family transcriptional regulator 7.2e-5 ●●●○○ -2.25 -2.25205665461304
Escherichia coli O157:H7 str. EDL933  Z1403  AAG55534.1  214 aa putative regulator 0.014 ●●●○○ -2.25 -2.25173430625925
Vibrio parahaemolyticus RIMD 2210633  VP_1780  BAC60043.1  Q87NT8  60 aa hypothetical protein 0.028 ●●●○○ -2.25 -2.25085196114016
Streptococcus pyogenes M1 5448  SP5448_05105  WP_002995035.1  468 aa citrate transporter 0.034 ●●●○○ -2.25 -2.25066530028872
Mycobacterium avium subsp. paratuberculosis K10  MAP_0404c  AAS02721.1  Q744D7  ephE  321 aa EphE 0.01 ●●●○○ -2.25 -2.25029559557863
Acinetobacter baumannii ATCC 17978  A1S_0241  ABO10716.2  306 aa site-specific tyrosine recombinase 6.3e-14 ●●●○○ -2.25 -2.2500964201407
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4189  WP_001062055.1  E8XJJ3  413 aa coproporphyrinogen III oxidase family protein 2.9e-17 ●●●○○ -2.25 -2.24887435942775
Streptococcus pyogenes M1 5448  SP5448_03470  WP_011285632.1  88 aa DUF4177 domain-containing protein 0.032 ●●●○○ -2.25 -2.2458586177984
Streptococcus pyogenes M1 5448  SP5448_07815  WP_010921936.1  275 aa exodeoxyribonuclease III 0.038 ●●●○○ -2.25 -2.2458586177984
Streptococcus pyogenes M1 5448  SP5448_09040  WP_010922747.1  285 aa VOC family protein 0.048 ●●●○○ -2.25 -2.2458586177984
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4744  WP_014344524.1  E8XCI6  343 aa SIS domain-containing protein 8.1e-5 ●●●○○ -2.24 -2.24455195654635
Mycobacterium avium subsp. paratuberculosis K10  MAP_3714  AAS06264.1  Q73TK4  fadD2  561 aa FadD2 0.011 ●●●○○ -2.24 -2.24381705162436
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0666  CBW16765.1  A0A0H3NAQ1  nagB  266 aa glucosamine-6-phosphate deaminase 5.4e-5 ●●●○○ -2.24 -2.24320251592827
Escherichia coli M12  CO715_11715  ATI06313.1  257 aa zinc transporter ZupT 3.2e-17 ●●●○○ -2.24 -2.24306278796079
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0128  NP_232529.1  Q9KN37  rbsA  500 aa D-ribose transporter ATP-binding protein 1.1e-5 ●●●○○ -2.24 -2.24272108478126
Acinetobacter baumannii ATCC 17978  A1S_2868  ABO13274.1  275 aa hypothetical protein 1.5e-5 ●●●○○ -2.24 -2.24201456682218
Streptococcus pyogenes M1 5448  SP5448_07495  WP_002990747.1  288 aa Rgg/GadR/MutR family transcriptional regulator 0.028 ●●●○○ -2.24 -2.24201327180614
Vibrio parahaemolyticus RIMD 2210633  VP_0924  BAC59186.1  Q87R75  202 aa hypothetical protein 0.028 ●●●○○ -2.24 -2.24083985089494
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3905  CBW19996.1  A0A0H3NUG9  uvrD  720 aa DNA helicase II 2.2e-6 ●●●○○ -2.24 -2.24013337622903
Escherichia coli CFT073  c1975  AAN80435.1  Q8FHC4  ynfC  248 aa Hypothetical protein ynfC 0.036 ●●●○○ -2.24 -2.23928692714784
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2862  AIK81451.1  220 aa iron-sulfur cluster repair di-iron protein 2.9e-9 ●●●○○ -2.24 -2.23858986287854
Vibrio parahaemolyticus RIMD 2210633  VPA_1562  BAC62905.1  Q87FW6  181 aa putative transcriptional regulator 0.04 ●●●○○ -2.24 -2.23841263662664
Acinetobacter baumannii ATCC 17978  A1S_1125  ABO11555.2  291 aa putative transferase 1.4e-35 ●●●○○ -2.24 -2.23819874372992
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2606  WP_000773647.1  E8XGJ4  737 aa sensor domain-containing phosphodiesterase 9.2e-5 ●●●○○ -2.24 -2.23697132376163
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5042  AIK83568.1  355 aa hisB <1e-323 ●●●○○ -2.24 -2.23675219941848
Escherichia coli O157:H7 str. EDL933  Z4898  AAG58630.1  680 aa oligopeptidase A 0.015 ●●●○○ -2.24 -2.23669191321641
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1354  NP_230998.2  Q9KSA5  rlmI  397 aa hypothetical protein 5.5e-9 ●●●○○ -2.24 -2.23652404891046
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3445  AIK82002.1  335 aa zinc-binding alcohol dehydrogenase family protein 9.3e-9 ●●●○○ -2.24 -2.23650073940503
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0860  WP_002852501.1  A0A0H3PHH5  93 aa YggT family protein 0.017 ●●●○○ -2.24 -2.23577674495
Escherichia coli M12  CO715_12750  ATI06499.1  196 aa phosphoheptose isomerase 7.0e-10 ●●●○○ -2.24 -2.23555153144783
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2620  AIK81214.1  157 aa hypothetical protein 2.2e-5 ●●●○○ -2.24 -2.23516484668183
Mycobacterium avium subsp. paratuberculosis K10  MAP_0868c  AAS03185.1  Q742G7  359 aa hypothetical protein 0.011 ●●●○○ -2.23 -2.23436967643235
Streptococcus pyogenes M1 5448  SP5448_05070  WP_010922330.1  510 aa citrate lyase subunit alpha 0.027 ●●●○○ -2.23 -2.23336124332356
Mycobacterium avium subsp. paratuberculosis K10  MAP_3541c  AAS06091.1  Q73U27  376 aa hypothetical protein 0.011 ●●●○○ -2.23 -2.23277586888285
Streptococcus pyogenes M1 5448  SP5448_01575  WP_009880482.1  448 aa type I glutamate--ammonia ligase 0.007 ●●●○○ -2.23 -2.23143857032743
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0003  NP_062587.1  Q9KVY5  mnmE  464 aa tRNA modification GTPase TrmE 2.0e-8 ●●●○○ -2.23 -2.23094440933541
Vibrio parahaemolyticus RIMD 2210633  VP_2670  BAC60933.1  Q87LE2  488 aa RNA polymerase sigma-54 factor 0.029 ●●●○○ -2.23 -2.23083346174841
Streptococcus pyogenes M1 5448  SP5448_03400  WP_002989112.1  564 aa phospho-sugar mutase 0.03 ●●●○○ -2.23 -2.2295158973313
Vibrio parahaemolyticus RIMD 2210633  VP_2916  BAC61179.1  Q87KR0  hemE  355 aa uroporphyrinogen decarboxylase 0.029 ●●●○○ -2.23 -2.22901143308912
Vibrio parahaemolyticus RIMD 2210633  VP_2986  BAC61249.1  Q87KJ1  cyaY  104 aa CyaY protein 0.029 ●●●○○ -2.23 -2.22901143308912
Mycobacterium avium subsp. paratuberculosis K10  MAP_3146c  AAS05694.1  Q73V68  pgmA  547 aa PgmA 0.011 ●●●○○ -2.23 -2.22692704483972
Escherichia coli M12  CO715_04360  ATI05046.1  429 aa phosphoribosylamine--glycine ligase 2.3e-16 ●●●○○ -2.22 -2.2234500626214
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3539  AIK82095.1  331 aa D-xylose ABC transporter, D-xylose-binding protein <1e-323 ●●●○○ -2.22 -2.22274847162684
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1687  WP_000208473.1  E8XK03  196 aa TetR/AcrR family transcriptional regulator 3.8e-17 ●●●○○ -2.22 -2.2225841549492
Escherichia coli O157:H7 str. EDL933  Z5120  AAG58833.1  675 aa escV 0.015 ●●●○○ -2.22 -2.22193229512334
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1488  WP_002797496.1  A0A0H3PIE6  142 aa hypothetical protein 0.018 ●●●○○ -2.22 -2.22152254002
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_1488  WP_002855458.1  A0A0H3PIE6  172 aa hypothetical protein 0.018 ●●●○○ -2.22 -2.22152254002
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2077  AIK80682.1  256 aa short chain dehydrogenase family protein 9.1e-5 ●●●○○ -2.22 -2.22147455174209
Streptococcus pyogenes M1 5448  SP5448_04490  WP_011018131.1  88 aa hypothetical protein 0.045 ●●●○○ -2.22 -2.21990253235065
Mycobacterium avium subsp. paratuberculosis K10  MAP_4031  AAS06581.1  Q73SP2  156 aa hypothetical protein 0.011 ●●●○○ -2.22 -2.21955838529882
Escherichia coli M12  CO715_07050  ATI05493.1  75 aa DNA-binding protein 1.7e-13 ●●●○○ -2.22 -2.21906849632217
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4529  WP_001229227.1  E8X9Y3  yjeJ  285 aa hypothetical protein 3.8e-6 ●●●○○ -2.22 -2.21717591172156
Vibrio parahaemolyticus RIMD 2210633  VP_1133  BAC59396.1  Q87QL6  135 aa DNA-binding protein H-NS 0.03 ●●●○○ -2.22 -2.21701985955463
Streptococcus pyogenes M1 5448  SP5448_02190  WP_002983385.1  263 aa aminoglycoside phosphotransferase 0.031 ●●●○○ -2.22 -2.21605718635839
Escherichia coli M12  CO715_18290  ATI07494.1  165 aa SprT family protein 8.6e-17 ●●●○○ -2.22 -2.21510422205144
Streptococcus pyogenes M1 5448  SP5448_00945  WP_076634046.1  547 aa transcription antiterminator 0.043 ●●●○○ -2.22 -2.21509584986033
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0939  NP_233323.1  Q9KL11  321 aa sensory box/GGDEF family protein 2.0e-7 ●●●○○ -2.21 -2.21207807965017
Mycobacterium avium subsp. paratuberculosis K10  MAP_2430  AAS04747.1  Q73X79  467 aa hypothetical protein 0.011 ●●●○○ -2.21 -2.21172364383759
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3716  WP_001038951.1  E8XEQ2  323 aa DMT family transporter 5.2e-17 ●●●○○ -2.21 -2.20977678670273
Vibrio parahaemolyticus RIMD 2210633  VP_2186  BAC60449.1  Q87MP5  163 aa bacteriocin production protein 0.03 ●●●○○ -2.21 -2.20870041522905
Acinetobacter baumannii ATCC 17978  A1S_2031  ABO12458.2  156 aa hypothetical protein 2.9e-8 ●●●○○ -2.21 -2.20817428221294
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0015  WP_000534902.1  E8XG35  315 aa LysR family transcriptional regulator 2.3e-18 ●●●○○ -2.21 -2.2078839468573
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3302  WP_001059119.1  E8XAK2  yghW  95 aa DUF2623 domain-containing protein 1.1e-6 ●●●○○ -2.21 -2.20780584919346
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4406  WP_000907494.1  E8X8X4  174 aa phage major tail tube protein 6.2e-16 ●●●○○ -2.21 -2.20778684487119
Vibrio parahaemolyticus RIMD 2210633  VPA_0398  BAC61741.1  Q87J55  35 aa hypothetical protein 0.043 ●●●○○ -2.21 -2.2070111018099
Vibrio parahaemolyticus RIMD 2210633  VP_2846  BAC61109.1  Q87KX8  340 aa conserved hypothetical protein 0.03 ●●●○○ -2.21 -2.20615610052871
Escherichia coli O157:H7 str. EDL933  Z5134  AAG58846.1  89 aa escS 0.016 ●●●○○ -2.21 -2.20589370813502
Acinetobacter baumannii ATCC 17978  A1S_1683  ABO12110.2  403 aa o-succinylhomoserine sulfhydrylase 1.4e-14 ●●●○○ -2.2 -2.20423622340471
Vibrio parahaemolyticus RIMD 2210633  VP_0471  BAC58734.1  Q87SF3  carB  1077 aa carbamoyl-phosphate synthase, large subunit 0.031 ●●●○○ -2.2 -2.20248648161302
Vibrio parahaemolyticus RIMD 2210633  VPA_0644  BAC61987.1  Q87IG2  34 aa hypothetical protein 0.043 ●●●○○ -2.2 -2.20226474657675
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2731  NP_232358.1  P45780  epsF  406 aa general secretion pathway protein F 2.9e-9 ●●●○○ -2.2 -2.20216188334646
Acinetobacter baumannii ATCC 17978  A1S_1432  ABO11860.2  472 aa hypothetical protein 1.6e-24 ●●●○○ -2.2 -2.20197203390961
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2190  WP_000605938.1  E8XCU3  manC  480 aa mannose-1-phosphate guanyltransferase 0.00042 ●●●○○ -2.2 -2.20121034708949
Mycobacterium avium subsp. paratuberculosis K10  MAP_0875c  AAS03192.1  Q742G0  ku  302 aa hypothetical protein 0.012 ●●●○○ -2.2 -2.20048936260528
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0558  WP_002869310.1  A1VYP2  sucC  387 aa ADP-forming succinate--CoA ligase subunit beta 0.018 ●●●○○ -2.2 -2.19926356122
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