Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4022  AIK82569.1  258 aa catalytic LigB subunit of aromatic ring-opening dioxygenase family protein 0.00021 ○○○○○ 0.13 0.130182483571403
Escherichia coli M12  CO715_05335  ATI05201.1  533 aa methyl-accepting chemotaxis protein 4.8e-6 ○○○○○ 0.13 0.130494270134255
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2561  AIK81158.1  134 aa hypothetical protein 4.8e-5 ○○○○○ 0.13 0.130856411741981
Escherichia coli M12  CO715_09635  ATI05945.1  235 aa DUF1266 domain-containing protein 0.00033 ○○○○○ 0.13 0.130911562162752
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2900  AIK81489.1  379 aa putative iron-sulfur cluster-binding protein 3.9e-12 ○○○○○ 0.13 0.13150631919556
Escherichia coli M12  CO715_02605  ATI04722.1  747 aa sensor domain-containing phosphodiesterase 3.3e-43 ○○○○○ 0.13 0.131537500205499
Escherichia coli M12  CO715_03315  ATI04850.1  445 aa integrase 5.6e-16 ○○○○○ 0.13 0.131746146219748
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4397  AIK82940.1  590 aa sulfite reductase [NADPH] flavoprotein, alpha-component 1.6e-9 ○○○○○ 0.13 0.132301666579157
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2885  AIK81474.1  810 aa ribonuclease R <1e-323 ○○○○○ 0.13 0.132454008575286
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0946  NP_233330.1  Q9KL04  malK  373 aa maltose/maltodextrin transporter ATP-binding protein 0.026 ○○○○○ 0.13 0.132588621061757
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1872  NP_231506.1  Q9KQX5  644 aa hypothetical protein 0.0082 ○○○○○ 0.13 0.132641659851265
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2209  AIK80814.1  213 aa isochorismatase family protein 0.00029 ○○○○○ 0.13 0.133067862706842
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3607  AIK82162.1  680 aa oligopeptidase A <1e-323 ○○○○○ 0.13 0.133311355112974
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2445  NP_232074.1  Q9KPC7  529 aa general secretion pathway protein A 0.025 ○○○○○ 0.13 0.133359408993814
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4676  AIK83210.1  792 aa SEC-C motif family protein 3.8e-15 ○○○○○ 0.13 0.133646951040825
Escherichia coli M12  CO715_15070  ATI06919.1  1417 aa intimin-like adhesin FdeC 7.5e-37 ○○○○○ 0.13 0.133832606362236
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3038  AIK81623.1  171 aa zur transcriptional repressor 8.3e-10 ○○○○○ 0.14 0.135309859521266
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4891  AIK83418.1  386 aa sulfate transporter family protein 0.0084 ○○○○○ 0.14 0.136584444357421
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2198  NP_231829.1  Q9KQ09  235 aa flagellar basal body rod modification protein 0.00019 ○○○○○ 0.14 0.136700996773052
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2679  NP_232307.1  Q9KNQ2  rpmE  72 aa 50S ribosomal protein L31 0.021 ○○○○○ 0.14 0.136800460092506
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0198  NP_229855.1  Q9KVE8  125 aa hypothetical protein 0.019 ○○○○○ 0.14 0.138250024733108
Escherichia coli M12  CO715_17885  ATI07422.1  956 aa molybdopterin-dependent oxidoreductase Mo/Fe-S-binding subunit 7.0e-6 ○○○○○ 0.14 0.138840110704209
Escherichia coli M12  CO715_01995  ATI04611.1  359 aa alanine racemase 2.3e-9 ○○○○○ 0.14 0.139257402732707
Escherichia coli M12  CO715_12105  ATI06386.1  1522 aa DUF4092 domain-containing protein 8.6e-8 ○○○○○ 0.14 0.139257402732707
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0422  NP_232816.1  Q9KMD9  97 aa hypothetical protein 0.014 ○○○○○ 0.14 0.139431993854809
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0902  NP_230549.2  Q9KTK0  queF  281 aa 7-cyano-7-deazaguanine reductase 0.0087 ○○○○○ 0.14 0.140447258009646
Escherichia coli M12  CO715_23800  ATI08466.1  217 aa oxygen-insensitive NAD(P)H nitroreductase 0.044 ○○○○○ 0.14 0.1405092788182
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4187  AIK82732.1  317 aa binding-protein-dependent transport system innermembrane component family protein <1e-323 ○○○○○ 0.14 0.140743754671497
Escherichia coli M12  CO715_14950  ATI06896.1  287 aa DUF2877 domain-containing protein 1.8e-23 ○○○○○ 0.14 0.141552508889444
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1482  NP_231123.1  Q9KS01  598 aa ATP-dependent protease LA-like protein 0.019 ○○○○○ 0.14 0.14178170911139
Porphyromonas gingivalis ATCC 33277  PGN_0151  WP_012457282.1  B2RH25  324 aa hypothetical protein 0.0018 ○○○○○ 0.14 0.141903436975281
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1229  NP_230874.1  Q9KSM7  291 aa hypothetical protein 0.03 ○○○○○ 0.14 0.142037216729761
Escherichia coli M12  CO715_01765  ATI04568.1  252 aa phosphonate C-P lyase system protein PhnK 0.0014 ○○○○○ 0.14 0.14238709294644
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1435  NP_231078.1  Q9KS26  224 aa hypothetical protein 0.00034 ○○○○○ 0.14 0.142488187818399
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0743  NP_230392.1  Q9KTY7  secD  617 aa preprotein translocase subunit SecD 0.028 ○○○○○ 0.14 0.142826808073765
Escherichia coli M12  CO715_23325  ATI08392.1  404 aa IS3 family transposase 0.037 ○○○○○ 0.14 0.143013030989186
Escherichia coli M12  CO715_19225  ATI07661.1  457 aa ATP-dependent RNA helicase DbpA 0.0075 ○○○○○ 0.14 0.143221677003435
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1696  NP_231332.2  Q9KRE6  77 aa DNA-binding protein 9.1e-5 ○○○○○ 0.14 0.143295084272734
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4167  AIK82713.1  192 aa 3-octaprenyl-4-hydroxybenzoate decarboxylase together with UbiG <1e-323 ○○○○○ 0.14 0.14351725596482
Escherichia coli M12  CO715_14735  ATI06858.1  367 aa branched chain amino acid ABC transporter substrate-binding protein 2.5e-9 ○○○○○ 0.14 0.144264907074679
Escherichia coli M12  CO715_17905  ATI07426.1  162 aa effector protein 2.7e-7 ○○○○○ 0.14 0.144682199103177
Escherichia coli M12  CO715_15285  ATI08825.1  70 aa CopG family transcriptional regulator 6.5e-25 ○○○○○ 0.15 0.145308137145924
Escherichia coli M12  CO715_11595  ATI06292.1  69 aa cold-shock protein CspC 0.018 ○○○○○ 0.15 0.145308137145924
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1196  NP_230841.1  Q9KSR0  229 aa hypothetical protein 0.039 ○○○○○ 0.15 0.14531896088012
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3033  AIK81618.1  327 aa qor <1e-323 ○○○○○ 0.15 0.145404567889244
Escherichia coli M12  CO715_21835  ATI08137.1  346 aa galactitol-1-phosphate 5-dehydrogenase 2.2e-22 ○○○○○ 0.15 0.145725429174421
Porphyromonas gingivalis ATCC 33277  PGN_0596  WP_012457631.1  B2RIC0  87 aa DUF3989 domain-containing protein <1e-323 ○○○○○ 0.15 0.145976200760067
Escherichia coli M12  CO715_08465  ATI05742.1  106 aa PTS sugar transporter IIB 0.00073 ○○○○○ 0.15 0.146142721202919
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2912  AIK81498.1  596 aa fumarate reductase, flavoprotein subunit <1e-323 ○○○○○ 0.15 0.14675561601027
Escherichia coli M12  CO715_22605  ATI08272.1  228 aa RNA methyltransferase 0.0054 ○○○○○ 0.15 0.146768659245666
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2159  NP_231790.1  Q9KQ45  180 aa glycine cleavage system transcriptional repressor 0.043 ○○○○○ 0.15 0.147223050707644
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1510  NP_231151.1  Q9KRX3  140 aa hypothetical protein 0.025 ○○○○○ 0.15 0.147361778349142
Escherichia coli M12  CO715_02070  ATI04624.1  526 aa hypothetical protein 2.0e-11 ○○○○○ 0.15 0.148020535331159
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2418  NP_232048.1  Q9KPF0  250 aa thiol:disulfide interchange protein DsbC 0.0056 ○○○○○ 0.15 0.148142505203201
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2616  AIK81210.1  293 aa bacterial regulatory helix-turn-helix, AraC family protein <1e-323 ○○○○○ 0.15 0.148222531085661
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1169  NP_230814.1  Q9KST7  trpA  268 aa tryptophan synthase subunit alpha 0.0052 ○○○○○ 0.15 0.148302141644861
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2910  AIK81496.1  500 aa amino acid permease family protein <1e-323 ○○○○○ 0.15 0.148742628452305
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4850  AIK83377.1  306 aa ribonuclease Z 0.006 ○○○○○ 0.15 0.148750136263906
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4415  AIK82958.1  400 aa sugar (and other) transporter family protein <1e-323 ○○○○○ 0.15 0.148938923240239
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4295  AIK82840.1  950 aa peptidase M16 inactive domain protein <1e-323 ○○○○○ 0.15 0.149278858826184
Porphyromonas gingivalis ATCC 33277  PGN_0598  WP_012457633.1  B2RIC2  traJ  328 aa conjugative transposon protein TraJ 3.4e-5 ○○○○○ 0.15 0.150066176133061
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2789  AIK81378.1  273 aa putative cytoplasmic protein 0.002 ○○○○○ 0.15 0.150234678510521
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1364  NP_231008.1  Q9KS95  273 aa hypothetical protein 0.017 ○○○○○ 0.15 0.151155390435085
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0981  NP_230627.1  Q9KTC2  189 aa phosphodiesterase 0.018 ○○○○○ 0.15 0.151252301428609
Escherichia coli M12  CO715_15985  ATI07078.1  472 aa polynucleotide adenylyltransferase PcnB 0.016 ○○○○○ 0.15 0.15156751757339
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4231  AIK82776.1  219 aa gram-negative pili assembly chaperone, C-terminal domain protein 9.1e-7 ○○○○○ 0.15 0.151758813464582
Escherichia coli M12  CO715_06115  ATI05329.1  291 aa 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase 0.0014 ○○○○○ 0.15 0.152819393658883
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_5038  AIK83564.1  199 aa phosphoribosyl-ATP diphosphatase 1.2e-11 ○○○○○ 0.15 0.152878373566098
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1983  AIK80589.1  113 aa bacterial regulatory helix-turn-helix, AraC family protein 0.00048 ○○○○○ 0.15 0.15435400479579
Escherichia coli M12  CO715_24780  ATI08639.1  457 aa oxygen-independent coproporphyrinogen III oxidase 1.0e-8 ○○○○○ 0.15 0.154697207787123
Escherichia coli M12  CO715_14765  ATI06864.1  255 aa ABC transporter ATP-binding protein 0.00073 ○○○○○ 0.15 0.154697207787123
Escherichia coli M12  CO715_09235  ATI05878.1  433 aa dicarboxylate/amino acid:cation symporter 4.5e-17 ○○○○○ 0.16 0.155531791844118
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3460  AIK82016.1  329 aa sulfate ABC transporter, sulfate-binding family protein <1e-323 ○○○○○ 0.16 0.156056929672806
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3065  AIK81649.1  80 aa hypothetical protein 0.014 ○○○○○ 0.16 0.156305448878641
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2180  NP_231811.1  Q9KQ24  hemA  419 aa glutamyl-tRNA reductase 0.03 ○○○○○ 0.16 0.156474655538255
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2633  NP_232261.1  Q9KNU7  196 aa fimbrial assembly protein PilN 0.0036 ○○○○○ 0.16 0.156993683284674
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1369  NP_231013.1  Q9KS90  338 aa hypothetical protein 0.0077 ○○○○○ 0.16 0.157103463138734
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1601  NP_231241.1  Q9KRN5  267 aa hypothetical protein 0.011 ○○○○○ 0.16 0.157786327253661
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4327  AIK82872.1  319 aa cobalamin biosynthesis protein CobD 1.3e-14 ○○○○○ 0.16 0.157956876865854
Escherichia coli M12  CO715_05395  ATI05212.1  366 aa cytochrome C 0.00053 ○○○○○ 0.16 0.158035544015104
Porphyromonas gingivalis ATCC 33277  PGN_0654  WP_012457676.1  B2RIH8  313 aa hypothetical protein 6.1e-12 ○○○○○ 0.16 0.158311768880742
Escherichia coli M12  CO715_02120  ATI04633.1  698 aa hypothetical protein 2.2e-5 ○○○○○ 0.16 0.158452836043602
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0417  NP_232811.1  Q9K330  178 aa acetyltransferase 0.0027 ○○○○○ 0.16 0.159879992353617
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4403  AIK82946.1  475 aa cysN 0.032 ○○○○○ 0.16 0.160277900213167
Escherichia coli M12  CO715_17320  ATI07324.1  446 aa glucarate dehydratase 0.012 ○○○○○ 0.16 0.161165234228837
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4108  AIK82654.1  406 aa major Facilitator Superfamily protein 1.3e-7 ○○○○○ 0.16 0.161829964919963
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2808  AIK81397.1  153 aa aspartate carbamoyltransferase, regulatory subunit 0.0026 ○○○○○ 0.16 0.162146644679859
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0868  NP_230515.1  Q9KTN3  70 aa hypothetical protein 0.012 ○○○○○ 0.16 0.162925565548214
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0568  NP_232958.1  Q9KM21  388 aa hypothetical protein 0.033 ○○○○○ 0.16 0.162947228878679
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1126  AIK79749.1  400 aa major Facilitator Superfamily protein 0.0076 ○○○○○ 0.16 0.163400413483504
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3596  AIK82151.1  440 aa H+ symporter family protein 1.1e-9 ○○○○○ 0.16 0.163865278455257
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4507  AIK83045.1  326 aa proX 2.1e-11 ○○○○○ 0.16 0.164074727870543
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2936  AIK81522.1  433 aa transporter, anaerobic C4-dicarboxylate uptake family protein <1e-323 ○○○○○ 0.16 0.164215322012929
Escherichia coli M12  CO715_16625  ATI07198.1  473 aa type III effector 3.8e-31 ○○○○○ 0.16 0.16429492444257
Escherichia coli M12  CO715_14555  ATI06824.1  524 aa nickel ABC transporter, nickel/metallophore periplasmic binding protein 2.6e-6 ○○○○○ 0.16 0.16429492444257
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4546  AIK83084.1  355 aa 2OG-Fe(II) oxygenase superfamily protein <1e-323 ○○○○○ 0.16 0.164488215373729
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4174  AIK82719.1  405 aa alpha/beta hydrolase fold family protein <1e-323 ○○○○○ 0.16 0.16458215567785
Escherichia coli M12  CO715_16010  ATI07082.1  186 aa fimbrial protein 4.2e-26 ○○○○○ 0.17 0.165129508499566
Escherichia coli M12  CO715_14215  ATI06759.1  809 aa ATP-dependent helicase HrpB 0.0085 ○○○○○ 0.17 0.165129508499566
Escherichia coli M12  CO715_15200  ATI06941.1  421 aa MFS transporter 3.4e-8 ○○○○○ 0.17 0.165546800528063
Retrieved entries 32,101–32,200 out of 36,363 total in 5.7 ms (Link to these results)