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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_11480  ATI06271.1  321 aa oxidoreductase 0.03 ●●○○○ -1.63 -1.62630516984116
Escherichia coli M12  CO715_14390  ATI06791.1  120 aa arsenical resistance operon transcriptional repressor ArsD 0.00034 ●●○○○ -1.63 -1.62547058578416
Escherichia coli M12  CO715_15165  ATI06936.1  236 aa hypothetical protein 8.7e-22 ●●○○○ -1.62 -1.62484464774142
Escherichia coli M12  CO715_07080  ATI05499.1  122 aa lambda prophage-derived protein ea10 8.9e-56 ●●○○○ -1.62 -1.62421870969867
Escherichia coli M12  CO715_21640  ATI08100.1  243 aa osmoprotectant uptake system permease 1.3e-7 ●●○○○ -1.62 -1.62421870969867
Escherichia coli M12  CO715_16460  ATI07166.1  428 aa chaperone SurA 1.3e-12 ●●○○○ -1.62 -1.62380141767017
Escherichia coli M12  CO715_07330  ATI05542.1  132 aa hydrogenase-1 operon protein HyaE 0.0043 ●●○○○ -1.62 -1.62380141767017
Escherichia coli M12  CO715_17135  ATI07289.1  302 aa sulfate adenylyltransferase subunit 2 7.0e-8 ●●○○○ -1.62 -1.62234089557043
Escherichia coli M12  CO715_20540  ATI07902.1  164 aa FMN reductase 0.00021 ●●○○○ -1.62 -1.62234089557043
Escherichia coli M12  CO715_05695  ATI05264.1  81 aa hypothetical protein 4.1e-10 ●●○○○ -1.62 -1.61941985137094
Escherichia coli M12  CO715_02245  ATI04657.1  309 aa homoserine O-succinyltransferase 0.03 ●●○○○ -1.62 -1.61941985137094
Escherichia coli M12  CO715_21660  ATI08104.1  239 aa DNA-binding response regulator 0.00012 ●●○○○ -1.62 -1.6192112053567
Escherichia coli M12  CO715_02665  ATI04734.1  282 aa formate transporter FocA 2.2e-7 ●●○○○ -1.62 -1.61858526731395
Escherichia coli M12  CO715_09910  ATI05996.1  285 aa isochorismatase 9.0e-11 ●●○○○ -1.62 -1.61816797528545
Escherichia coli M12  CO715_20625  ATI07917.1  354 aa phosphate starvation protein PhoH 0.00022 ●●○○○ -1.62 -1.61816797528545
Escherichia coli M12  CO715_05125  ATI05166.1  121 aa flagellar protein FliT 0.0017 ●●○○○ -1.62 -1.61733339122846
Escherichia coli M12  CO715_11670  ATI06304.1  433 aa inorganic triphosphatase 0.00024 ●●○○○ -1.61 -1.61462099304322
Escherichia coli M12  CO715_22085  ATI08182.1  279 aa transcriptional regulator 0.0049 ●●○○○ -1.61 -1.61399505500047
Escherichia coli M12  CO715_11590  ATI06291.1  269 aa 23S rRNA (guanine(745)-N(1))-methyltransferase 1.8e-16 ●●○○○ -1.61 -1.61316047094348
Escherichia coli M12  CO715_01655  ATI04550.1  302 aa melibiose operon regulatory protein 1.2e-20 ●●○○○ -1.61 -1.61044807275824
Escherichia coli M12  CO715_16170  ATI07112.1  183 aa 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.031 ●●○○○ -1.61 -1.6098221347155
Escherichia coli M12  CO715_08625  ATI05772.1  303 aa glutathione ABC transporter permease GsiD 6.9e-9 ●●○○○ -1.61 -1.60857025863
Escherichia coli M12  CO715_19630  ATI08869.1  452 aa bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 2.9e-9 ●●○○○ -1.61 -1.60710973653026
Escherichia coli M12  CO715_08090  ATI08766.1  182 aa hypothetical protein 2.7e-6 ●●○○○ -1.61 -1.60648379848752
Escherichia coli M12  CO715_07905  ATI05641.1  120 aa hypothetical protein 6.9e-16 ●●○○○ -1.6 -1.60481463037352
Escherichia coli M12  CO715_19850  ATI07773.1  72 aa hemolysin expression-modulating protein Hha 0.0018 ●●○○○ -1.6 -1.60439733834503
Escherichia coli M12  CO715_17195  ATI07299.1  244 aa phosphoadenosine phosphosulfate reductase 8.3e-9 ●●○○○ -1.6 -1.60356275428803
Escherichia coli M12  CO715_01550  ATI04531.1  191 aa transcriptional regulator 0.00017 ●●○○○ -1.6 -1.60356275428803
Escherichia coli M12  CO715_19965  ATI07794.1  207 aa ATP-dependent Clp protease proteolytic subunit 0.0022 ●●○○○ -1.6 -1.60126764813129
Escherichia coli M12  CO715_05495  ATI05230.1  480 aa pyruvate kinase 1.9e-55 ●●○○○ -1.6 -1.6008503561028
Escherichia coli M12  CO715_17165  ATI07294.1  351 aa type I-E CRISPR-associated protein Cas7/Cse4/CasC 2.2e-34 ●●○○○ -1.6 -1.6000157720458
Escherichia coli M12  CO715_09610  ATI05940.1  224 aa amino acid ABC transporter permease 8.5e-18 ●●○○○ -1.6 -1.5995984800173
Escherichia coli M12  CO715_16480  ATI07170.1  280 aa bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 3.1e-6 ●●○○○ -1.6 -1.5995984800173
Escherichia coli M12  CO715_02370  ATI04679.1  265 aa lipopolysaccharide core heptose(I) kinase RfaP 2.7e-18 ●●○○○ -1.6 -1.59938983400305
Escherichia coli M12  CO715_05755  ATI05274.1  192 aa phage tail protein 6.3e-5 ●●○○○ -1.6 -1.59751201987481
Escherichia coli M12  CO715_20975  ATI07982.1  413 aa beta-ketoacyl-[acyl-carrier-protein] synthase II 0.00063 ●●○○○ -1.6 -1.59709472784632
Escherichia coli M12  CO715_11175  ATI06214.1  492 aa N-succinylglutamate 5-semialdehyde dehydrogenase 4.8e-8 ●●○○○ -1.6 -1.59646878980357
Escherichia coli M12  CO715_15915  ATI07065.1  89 aa twin-arginine translocase subunit TatA 3.3e-5 ●●○○○ -1.59 -1.59479962168958
Escherichia coli M12  CO715_06595  ATI05412.1  210 aa dihydroxyacetone kinase subunit L 0.0085 ●●○○○ -1.59 -1.5902094093761
Escherichia coli M12  CO715_16910  ATI07248.1  321 aa arabinose-5-phosphate isomerase GutQ 7.9e-11 ●●○○○ -1.59 -1.58958347133336
Escherichia coli M12  CO715_02675  ATI04736.1  137 aa formate hydrogenlyase maturation protein HycH 6.5e-29 ●●○○○ -1.59 -1.58895753329061
Escherichia coli M12  CO715_18425  ATI07521.1  235 aa hypothetical protein 2.2e-14 ●●○○○ -1.59 -1.58895753329061
Escherichia coli M12  CO715_02625  ATI04726.1  345 aa phosphoribosylformylglycinamidine cyclo-ligase 4.6e-39 ●●○○○ -1.59 -1.58791430321937
Escherichia coli M12  CO715_09975  ATI08774.1  206 aa enterobactin synthase subunit EntD 2.4e-8 ●●○○○ -1.59 -1.58645378111962
Escherichia coli M12  CO715_04755  ATI08727.1  104 aa flagellar hook-basal body complex protein FliE 5.7e-54 ●●○○○ -1.59 -1.58520190503413
Escherichia coli M12  CO715_12695  ATI06488.1  144 aa PTS N-acetylgalactosamine transporter subunit IIA 1.9e-52 ●●○○○ -1.58 -1.58478461300563
Escherichia coli M12  CO715_00970  ATI04429.1  445 aa NCS2 family permease 1.1e-9 ●●○○○ -1.58 -1.58311544489164
Escherichia coli M12  CO715_20275  ATI07853.1  364 aa D-alanine--D-alanine ligase 1.5e-9 ●●○○○ -1.58 -1.57873387859242
Escherichia coli M12  CO715_04305  ATI05036.1  158 aa sigma D regulator 3.4e-7 ●●○○○ -1.58 -1.57852523257817
Escherichia coli M12  CO715_20870  ATI07961.1  401 aa flagellar hook protein FlgE 1.3e-6 ●●○○○ -1.58 -1.57685606446418
Escherichia coli M12  CO715_12010  ATI06368.1  252 aa hypothetical protein 1.5e-17 ●●○○○ -1.58 -1.57643877243568
Escherichia coli M12  CO715_05540  ATI05239.1  389 aa transposase 3.3e-9 ●●○○○ -1.57 -1.57497825033594
Escherichia coli M12  CO715_08235  ATI05702.1  208 aa hydrolase 0.00013 ●●○○○ -1.57 -1.57476960432169
Escherichia coli M12  CO715_08990  ATI05840.1  331 aa 6-phosphogluconolactonase 0.00017 ●●○○○ -1.57 -1.57435231229319
Escherichia coli M12  CO715_02940  ATI04784.1  299 aa peroxidase 9.8e-6 ●●○○○ -1.57 -1.57393502026469
Escherichia coli M12  CO715_06910  ATI05468.1  285 aa metal ABC transporter permease 0.00015 ●●○○○ -1.57 -1.5731004362077
Escherichia coli M12  CO715_14860  ATI06880.1  483 aa 2-methylcitrate dehydratase 5.8e-28 ●●○○○ -1.57 -1.5722658521507
Escherichia coli M12  CO715_03770  ATI04935.1  111 aa 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE 0.00032 ●●○○○ -1.57 -1.56871886990847
Escherichia coli M12  CO715_15875  ATI07057.1  753 aa 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 9.5e-80 ●●○○○ -1.57 -1.56851022389422
Escherichia coli M12  CO715_16440  ATI07162.1  219 aa bifunctional tRNA pseudouridine(32) synthase/ribosomal large subunit pseudouridine synthase RluA 1.7e-17 ●●○○○ -1.57 -1.56830157787997
Escherichia coli M12  CO715_22565  ATI08266.1  317 aa transaldolase B 2.6e-6 ●●○○○ -1.57 -1.56684105578023
Escherichia coli M12  CO715_17010  ATI07264.1  290 aa hydrogenase accessory protein HypB 3.1e-6 ●●○○○ -1.57 -1.56684105578023
Escherichia coli M12  CO715_22130  ATI08190.1  514 aa threonine ammonia-lyase, biosynthetic 2.9e-9 ●●○○○ -1.57 -1.56663240976598
Escherichia coli M12  CO715_01940  ATI04600.1  107 aa regulatory protein SoxS 1.6e-6 ●●○○○ -1.57 -1.56579782570899
Escherichia coli M12  CO715_12575  ATI06467.1  129 aa reactive intermediate/imine deaminase 2.0e-11 ●●○○○ -1.57 -1.56558917969474
Escherichia coli M12  CO715_00180  ATI04289.1  444 aa ATP-dependent RNA helicase SrmB 1.1e-9 ●●○○○ -1.57 -1.56558917969474
Escherichia coli M12  CO715_24760  ATI08636.1  928 aa DNA polymerase I 0.00022 ●●○○○ -1.57 -1.56558917969474
Escherichia coli M12  CO715_11420  ATI06261.1  84 aa hypothetical protein 0.00037 ●●○○○ -1.57 -1.56558917969474
Escherichia coli M12  CO715_08285  ATI05711.1  321 aa thioredoxin-disulfide reductase 1.2e-8 ●●○○○ -1.56 -1.56454594962349
Escherichia coli M12  CO715_16365  ATI07149.1  201 aa 3-isopropylmalate dehydratase small subunit 0.00022 ●●○○○ -1.56 -1.56245948948101
Escherichia coli M12  CO715_04890  ATI05127.1  354 aa bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada 1.0e-13 ●●○○○ -1.56 -1.56225084346676
Escherichia coli M12  CO715_02890  ATI04775.1  453 aa ethanolamine ammonia-lyase heavy chain 3.9e-12 ●●○○○ -1.56 -1.56225084346676
Escherichia coli M12  CO715_13900  ATI06704.1  387 aa hypothetical protein 3.3e-7 ●●○○○ -1.56 -1.56183355143826
Escherichia coli M12  CO715_04155  ATI05007.1  184 aa glutathione-regulated potassium-efflux system ancillary protein KefG 8.4e-26 ●●○○○ -1.56 -1.55953844528152
Escherichia coli M12  CO715_12835  ATI06516.1  294 aa lipoprotein NlpI 0.007 ●●○○○ -1.56 -1.55807792318178
Escherichia coli M12  CO715_13075  ATI06558.1  778 aa hybrid sensor histidine kinase/response regulator 1.4e-22 ●●○○○ -1.56 -1.55724333912478
Escherichia coli M12  CO715_00705  ATI04382.1  196 aa DNA-binding response regulator 1.9e-14 ●●○○○ -1.55 -1.5543222949253
Escherichia coli M12  CO715_17505  ATI07356.1  187 aa prepilin-type cleavage/methylation domain-containing protein 0.0001 ●●○○○ -1.55 -1.55411364891105
Escherichia coli M12  CO715_06670  ATI05425.1  304 aa muramoyltetrapeptide carboxypeptidase 6.2e-7 ●●○○○ -1.55 -1.55369635688255
Escherichia coli M12  CO715_16110  ATI07101.1  264 aa S-adenosylmethionine decarboxylase proenzyme 0.00016 ●●○○○ -1.55 -1.5534877108683
Escherichia coli M12  CO715_10915  ATI06163.1  58 aa hypothetical protein 1.3e-9 ●●○○○ -1.55 -1.55244448079706
Escherichia coli M12  CO715_00330  ATI04318.1  417 aa serine hydroxymethyltransferase 0.036 ●●○○○ -1.55 -1.55098395869732
Escherichia coli M12  CO715_08500  ATI05749.1  370 aa spermidine/putrescine ABC transporter substrate-binding protein PotF 0.0077 ●●○○○ -1.55 -1.54973208261183
Escherichia coli M12  CO715_20675  ATI07926.1  216 aa transcriptional regulator CsgD 6.1e-35 ●●○○○ -1.55 -1.54806291449783
Escherichia coli M12  CO715_04540  ATI05071.1  600 aa ABC transporter ATP-binding protein 1.7e-5 ●●○○○ -1.55 -1.54785426848359
Escherichia coli M12  CO715_22585  ATI08269.1  428 aa threonine synthase 0.036 ●●○○○ -1.55 -1.54785426848359
Escherichia coli M12  CO715_14935  ATI06893.1  316 aa carbamate kinase 1.7e-24 ●●○○○ -1.55 -1.54722833044084
Escherichia coli M12  CO715_08575  ATI05764.1  252 aa DNA-binding transcriptional repressor DeoR 2.5e-10 ●●○○○ -1.55 -1.54701968442659
Escherichia coli M12  CO715_21795  ATI08130.1  334 aa ADP-ribosylglycohydrolase family protein 4.0e-13 ●●○○○ -1.54 -1.5445159322556
Escherichia coli M12  CO715_00205  ATI04294.1  318 aa sigma-E factor regulatory protein RseB 2.0e-6 ●●○○○ -1.54 -1.54222082609887
Escherichia coli M12  CO715_02865  ATI04771.1  467 aa aldehyde dehydrogenase EutE 5.2e-7 ●●○○○ -1.54 -1.53950842791363
Escherichia coli M12  CO715_03480  ATI04880.1  270 aa tRNA pseudouridine(38-40) synthase TruA 0.0068 ●●○○○ -1.54 -1.53950842791363
Escherichia coli M12  CO715_20830  ATI07953.1  307 aa virulence factor MviM 5.0e-11 ●●○○○ -1.54 -1.53888248987088
Escherichia coli M12  CO715_09495  ATI05925.1  266 aa glucosamine-6-phosphate deaminase 2.7e-14 ●●○○○ -1.54 -1.53804790581389
Escherichia coli M12  CO715_18275  ATI07492.1  384 aa S-adenosylmethionine synthase 0.0017 ●●○○○ -1.54 -1.53742196777114
Escherichia coli M12  CO715_18905  ATI07603.1  353 aa hypothetical protein 1.2e-20 ●●○○○ -1.54 -1.5355441536429
Escherichia coli M12  CO715_03120  ATI04814.1  108 aa hypothetical protein 2.8e-8 ●●○○○ -1.54 -1.5355441536429
Escherichia coli M12  CO715_02355  ATI04676.1  337 aa UDP-glucose--(galactosyl) LPS alpha1,2-glucosyltransferase 3.4e-10 ●●○○○ -1.53 -1.53470956958591
Escherichia coli M12  CO715_13545  ATI06639.1  69 aa hypothetical protein 7.6e-7 ●●○○○ -1.53 -1.53429227755741
Escherichia coli M12  CO715_08345  ATI05721.1  371 aa MacA family efflux pump subunit 2.1e-66 ●●○○○ -1.53 -1.53324904748616
Retrieved entries 301–400 out of 3,550 total in 50.2 ms (Link to these results)