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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0757  WP_000775561.1  E8XAW7  sdhA  588 aa succinate dehydrogenase flavoprotein subunit 2.1e-17 ●●●○○ -2.87 -2.86662011792421
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2971  CBW19070.1  A0A0H3NLQ8  recD  611 aa exonuclease V alpha-subunit 1.1e-9 ●●●○○ -2.87 -2.86538917800379
Serratia marcescens Strain UMH9  BVG96_21675  ASM00069.1  233 aa NAD(P)H-flavin reductase 0.0029 ●●●○○ -2.86 -2.86486602351704
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2419  NP_232049.1  Q9KPE9  xerD  302 aa site-specific tyrosine recombinase XerD 1.7e-11 ●●●○○ -2.86 -2.8639689970678
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0579  CBW16679.1  A0A0H3NAF3  fepG  329 aa ferric enterobactin transport protein FepG 1.0e-8 ●●●○○ -2.86 -2.86265208000554
Vibrio parahaemolyticus RIMD 2210633  VP_0797  BAC59060.1  Q87RJ7  322 aa cysteine synthase A 0.0058 ●●●○○ -2.86 -2.86089113091514
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2332  WP_000894640.1  E8XDS7  443 aa NTPase 4.2e-22 ●●●○○ -2.86 -2.86001312805927
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1359  NP_231003.1  Q9KSA0  251 aa amino acid ABC transporter ATP-binding protein 6.5e-11 ●●●○○ -2.86 -2.8552455966619
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3451  CBW19546.1  A0A0H3NSZ5  dam  278 aa DNA adenine methylase 7.9e-8 ●●●○○ -2.85 -2.85477791773724
Vibrio parahaemolyticus RIMD 2210633  VPA_1363  BAC62706.1  Q87GF3  96 aa putative chaperone 0.0084 ●●●○○ -2.85 -2.85022817101637
Streptococcus pyogenes M1 5448  SP5448_03635  WP_010922465.1  86 aa hypothetical protein 0.0082 ●●●○○ -2.85 -2.84861660208503
Streptococcus pyogenes M1 5448  SP5448_03635  WP_010922466.1  74 aa hypothetical protein 0.0082 ●●●○○ -2.85 -2.84861660208503
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3297  WP_000083044.1  E8XAJ7  hybC  567 aa hydrogenase 2 large subunit 2.7e-7 ●●●○○ -2.85 -2.84793790736516
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1622  CBW17717.1  A0A0H3NBS4  sapA  549 aa peptide transport periplasmic protein SapA precursor 2.0e-7 ●●●○○ -2.85 -2.84701983553652
Acinetobacter baumannii ATCC 17978  A1S_0688  ABO11132.2  A3M2I8  hisC  361 aa histidinol-phosphate aminotransferase 1.3e-43 ●●●○○ -2.85 -2.84520778647996
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3884  CBW19974.1  A0A0H3NHW2  rffA  376 aa lipopolysaccharide biosynthesis protein 4.6e-9 ●●●○○ -2.84 -2.84367239440839
Acinetobacter baumannii ATCC 17978  A1S_2251  ABO12674.2  513 aa amidophosphoribosyltransferase 5.8e-20 ●●●○○ -2.84 -2.84158648922185
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3958  WP_001152234.1  E8XGY1  157 aa PTS sugar transporter subunit IIA 5.6e-19 ●●●○○ -2.84 -2.84034503640969
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3204  WP_000111140.1  E8X9M8  ubiH  392 aa 2-octaprenyl-6-methoxyphenyl hydroxylase 3.2e-19 ●●●○○ -2.84 -2.83788008051745
Vibrio parahaemolyticus RIMD 2210633  VP_1211  BAC59474.1  Q87QD8  449 aa sensor histidine kinase 0.0062 ●●●○○ -2.84 -2.83755079492366
Vibrio parahaemolyticus RIMD 2210633  VP_2519  BAC60782.1  Q87LU2  887 aa pyruvate dehydrogenase, E1 component 0.0062 ●●●○○ -2.84 -2.83557718386571
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1965  CBW18062.1  A0A0H3NCU8  402 aa predicted bacteriophage protein 2.3e-9 ●●●○○ -2.83 -2.82892721744232
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1356  CBW17452.1  A0A0H3NCS1  ssaU  352 aa Type III secretion system protein 7.2e-7 ●●●○○ -2.83 -2.82852234212644
Mycobacterium avium subsp. paratuberculosis K10  MAP_0480  AAS02797.1  Q743W1  297 aa hypothetical protein 0.0024 ●●●○○ -2.83 -2.82754579201878
Serratia marcescens Strain UMH9  BVG96_04615  ASL96926.1  177 aa dTDP-4-dehydrorhamnose 3,5-epimerase 0.027 ●●●○○ -2.83 -2.82611074384897
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4610  WP_000977203.1  E8XBG6  387 aa metallo-dependent hydrolase 0.00022 ●●●○○ -2.82 -2.82306171793991
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3101  WP_000226838.1  E8X8P0  relA  744 aa GTP diphosphokinase 9.9e-8 ●●●○○ -2.82 -2.82067334331252
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4751  WP_000936657.1  E8XCJ3  yjjQ  241 aa response regulator transcription factor 9.5e-11 ●●●○○ -2.82 -2.81865209355431
Vibrio parahaemolyticus RIMD 2210633  VPA_1225  BAC62568.1  Q87GU0  51 aa hypothetical protein 0.0092 ●●●○○ -2.82 -2.81818582080665
Acinetobacter baumannii ATCC 17978  A1S_0471  ABO10926.2  A3M1Y2  metXS  386 aa homoserine O-acetyltransferase 5.9e-28 ●●●○○ -2.81 -2.81258875587926
Streptococcus pyogenes M1 5448  SP5448_08295  WP_010922659.1  635 aa FtsX-like permease family protein 0.003 ●●●○○ -2.81 -2.81208581515857
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0440  NP_232834.1  Q9KMC4  148 aa hypothetical protein 1.7e-8 ●●●○○ -2.81 -2.81050514144171
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3189  WP_000813394.1  E8X9L3  recJ  577 aa single-stranded-DNA-specific exonuclease RecJ 6.7e-7 ●●●○○ -2.81 -2.8097352702206
Vibrio parahaemolyticus RIMD 2210633  VP_2373  BAC60636.1  Q87M85  recD  715 aa exodeoxyribonuclease V, 67 kDa subunit 0.0067 ●●●○○ -2.81 -2.80746560269439
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2935  WP_001051100.1  E8XK41  133 aa DNA-binding protein StpA 6.7e-7 ●●●○○ -2.8 -2.80133615433023
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1373  WP_000418970.1  E8XGH4  sufA  122 aa Fe-S cluster assembly scaffold SufA 1.3e-6 ●●●○○ -2.8 -2.8011388739376
Vibrio parahaemolyticus RIMD 2210633  VP_1811  BAC60074.1  Q87NQ7  49 aa hypothetical protein 0.0069 ●●●○○ -2.8 -2.8000875502287
Acinetobacter baumannii ATCC 17978  A1S_0256  ABO10731.2  234 aa high affinity phosphate uptake transcriptional repressor 1.5e-16 ●●●○○ -2.8 -2.79999986570586
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1825  CBW17919.1  A0A0H3NCN2  znuA  333 aa high-affinity zinc uptake system periplasmic binding protein 3.0e-7 ●●●○○ -2.8 -2.79982503259041
Serratia marcescens Strain UMH9  BVG96_21315  ASL99998.1  274 aa diaminopimelate epimerase 0.0021 ●●●○○ -2.8 -2.79969001688169
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0204  WP_001090554.1  E8XHZ3  stfA  186 aa fimbrial major subunit StfA 0.00032 ●●●○○ -2.8 -2.79826281345096
Streptococcus pyogenes M1 5448  SP5448_01620  WP_002992274.1  400 aa NupC/NupG family nucleoside CNT transporter 0.011 ●●●○○ -2.8 -2.79670443118953
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0259  NP_229915.2  H9L4P1  370 aa lipopolysaccharide biosynthesis protein RfbV 1.3e-10 ●●●○○ -2.8 -2.79531819769152
Haemophilus influenzae Rd KW20  HI_1301  NP_439452.1  P45148  can  229 aa carbonic anhydrase 0.0068 ●●●○○ -2.8 -2.79518600500986
Vibrio parahaemolyticus RIMD 2210633  VP_2374  BAC60637.1  Q87M84  recB  1227 aa exodeoxyribonuclease V, 135 kDa subunit 0.007 ●●●○○ -2.8 -2.7951338314261
Vibrio parahaemolyticus RIMD 2210633  VP_0406  BAC58669.1  Q87SL6  147 aa conserved hypothetical protein 0.007 ●●●○○ -2.8 -2.7951338314261
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0307  WP_000994224.1  E8XIW0  91 aa type I addiction module toxin, SymE family 1.4e-7 ●●●○○ -2.79 -2.79465214230224
Acinetobacter baumannii ATCC 17978  A1S_0769  ABO11209.2  253 aa ferredoxin--NADP+ reductase 3.7e-6 ●●●○○ -2.79 -2.79286209829476
Streptococcus pyogenes M1 5448  SP5448_02780  WP_009880659.1  721 aa penicillin-binding protein 0.0099 ●●●○○ -2.79 -2.78901373920501
Vibrio parahaemolyticus RIMD 2210633  VP_2578  BAC60841.1  Q87LN3  192 aa RNA polymerase sigma-E factor 0.0071 ●●●○○ -2.79 -2.78890172375188
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0309  WP_002826355.1  A0A0H3PAG7  cheW  173 aa purine-binding chemotaxis protein CheW 0.0043 ●●●○○ -2.79 -2.78652603638
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2219  AIK80824.1  304 aa glucokinase family protein <1e-323 ●●●○○ -2.79 -2.78582075542143
Haemophilus influenzae Rd KW20  HI_0841  NP_439001.1  P44898  585 aa hypothetical protein 0.007 ●●●○○ -2.78 -2.78391203662548
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2994  WP_000337636.1  E8XKY3  hypB  290 aa hydrogenase nickel incorporation protein HypB 1.1e-6 ●●●○○ -2.78 -2.78241003566757
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4693  WP_001095590.1  E8XCD5  1225 aa BREX-1 system adenine-specific DNA-methyltransferase PglX 1.1e-21 ●●●○○ -2.78 -2.77993947169563
Vibrio parahaemolyticus RIMD 2210633  VP_2576  BAC60839.1  Q87LN5  320 aa sigma-E factor regulatory protein RseB 0.0073 ●●●○○ -2.78 -2.7793025843003
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2695  WP_000593433.1  E8XHG8  274 aa tail protein 4.7e-8 ●●●○○ -2.77 -2.77421065185465
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3939  CBW20030.1  A0A0H3NI08  trkH  483 aa trk system potassium uptake protein 2.2e-7 ●●●○○ -2.77 -2.7726836522706
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2862  WP_000155500.1  E8XJ87  341 aa site-specific integrase 1.3e-21 ●●●○○ -2.77 -2.77134089481011
Acinetobacter baumannii ATCC 17978  A1S_2529  ABO12946.2  356 aa hypothetical protein 7.1e-20 ●●●○○ -2.77 -2.76719160853959
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1696  WP_001235493.1  E8XK12  513 aa TyrR family transcriptional regulator 2.0e-16 ●●●○○ -2.77 -2.7655026055029
Escherichia coli CFT073  c1855  AAN80318.1  A0A0H2V768  42 aa Hypothetical protein 0.014 ●●●○○ -2.77 -2.76535015900051
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2361  WP_000884990.1  E8XEA7  alkB  216 aa DNA oxidative demethylase AlkB 7.9e-22 ●●●○○ -2.76 -2.7649722330121
Acinetobacter baumannii ATCC 17978  A1S_0373  ABO10833.2  496 aa apolipoprotein N-acyltransferase copper homeostasis protein 1.0e-41 ●●●○○ -2.76 -2.76370309390159
Vibrio parahaemolyticus RIMD 2210633  VP_0283  BAC58546.1  Q87SY9  rplQ  126 aa ribosomal protein L17 0.0076 ●●●○○ -2.76 -2.76351669994995
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0199  WP_000918127.1  E8XHY8  mrcB  840 aa bifunctional glycosyl transferase/transpeptidase 6.8e-17 ●●●○○ -2.76 -2.76296715938818
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1826  CBW17920.1  A0A0H3NMC7  znuC  251 aa high-affinity zinc uptake system ATP-binding protein 1.4e-6 ●●●○○ -2.76 -2.76136347386829
Haemophilus influenzae Rd KW20  HI_1640  NP_439782.1  P45287  sapC  295 aa peptide ABC transporter permease 0.0074 ●●●○○ -2.76 -2.76104451176055
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4907  AIK83433.1  114 aa yejG-like family protein 1.0e-6 ●●●○○ -2.76 -2.76040706237889
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2306  CBW18408.1  A0A0H3NDR5  ackA  400 aa acetate kinase 8.6e-7 ●●●○○ -2.76 -2.75973538448106
Acinetobacter baumannii ATCC 17978  A1S_0930  ABO11362.1  447 aa high-affinity choline transporter (BCCT family) 2.5e-35 ●●●○○ -2.76 -2.75744865981564
Streptococcus pyogenes M1 5448  SP5448_04965  WP_010922343.1  293 aa NAD-dependent deacetylase 0.00046 ●●●○○ -2.75 -2.75344428877661
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1087  WP_000240046.1  E8XE51  copS  454 aa heavy metal sensor histidine kinase 2.2e-20 ●●●○○ -2.75 -2.75290297457032
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2183  WP_000981469.1  E8XC52  galF  297 aa GalU regulator GalF 6.8e-21 ●●●○○ -2.75 -2.751946321551
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0879  WP_002856853.1  A0A0H3P9N9  xerH  354 aa integrase 0.0047 ●●●○○ -2.75 -2.7511222216
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2389  NP_232019.1  Q9KPH9  carB  1076 aa carbamoyl phosphate synthase large subunit 3.2e-11 ●●●○○ -2.75 -2.74752898576556
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2292  CBW18394.1  A0A0H3NJN6  nuoG  908 aa NADH dehydrogenase I chain G 1.3e-6 ●●●○○ -2.75 -2.74748404844115
Vibrio parahaemolyticus RIMD 2210633  VP_0140  BAC58403.1  Q87TD0  336 aa general secretion pathway protein K 0.008 ●●●○○ -2.74 -2.74397935420436
Streptococcus pyogenes M1 5448  SP5448_05220  WP_010922309.1  137 aa VOC family protein 0.013 ●●●○○ -2.74 -2.74383092379597
Escherichia coli CFT073  c1757  AAN80223.1  Q8FHT6  rnb  644 aa Exoribonuclease II 0.045 ●●●○○ -2.74 -2.74356999449681
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0379  NP_232773.1  Q9KMH5  131 aa hypothetical protein 2.9e-11 ●●●○○ -2.74 -2.74021096562399
Streptococcus pyogenes M1 5448  SP5448_05145  WP_009880716.1  238 aa DUF3307 domain-containing protein 0.0023 ●●●○○ -2.74 -2.73998557780371
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2291  CBW18393.1  A0A0H3NDQ1  nuoH  325 aa NADH dehydrogenase I chain H 6.0e-6 ●●●○○ -2.74 -2.73953983514405
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1179  WP_000096425.1  E8XEV2  flgK  553 aa flagellar hook-associated protein FlgK 4.5e-6 ●●●○○ -2.74 -2.73829379455954
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2710  NP_232337.1  Q9KNM2  spoT  705 aa bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 1.1e-8 ●●●○○ -2.74 -2.73736243297668
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4173  WP_001046887.1  E8XJH7  mobA  194 aa molybdenum cofactor guanylyltransferase MobA 4.9e-7 ●●●○○ -2.74 -2.73634017463832
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0382  WP_000205278.1  E8XJR6  prpR  541 aa propionate catabolism operon regulatory protein PrpR 5.2e-5 ●●●○○ -2.74 -2.73536145126261
Campylobacter jejuni subsp. jejuni 81-176  CJJ81176_0305  WP_002857581.1  A0A0H3PJH5  carB  1089 aa carbamoyl-phosphate synthase large subunit 0.0049 ●●●○○ -2.73 -2.73447180297
Serratia marcescens Strain UMH9  BVG96_20100  ASL99782.1  366 aa glycosyl transferase 0.0013 ●●●○○ -2.73 -2.73424611585086
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1201  NP_230846.1  Q9KSQ5  241 aa hypothetical protein 2.2e-10 ●●●○○ -2.73 -2.73383967352254
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2285  WP_000443208.1  E8XDN3  455 aa L-serine ammonia-lyase 1.4e-16 ●●●○○ -2.73 -2.73265543103416
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0666  NP_233055.1  Q9KLS5  476 aa L-serine dehydratase 1 2.7e-7 ●●●○○ -2.73 -2.73051445003167
Vibrio parahaemolyticus RIMD 2210633  VPA_1219  BAC62562.1  Q87GU6  154 aa putative transcription regulator 0.012 ●●●○○ -2.73 -2.73001294144048
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3520  WP_001257852.1  E8XD63  argR  156 aa transcriptional regulator ArgR 5.8e-7 ●●●○○ -2.73 -2.72847435134543
Mycobacterium avium subsp. paratuberculosis K10  MAP_0973  AAS03290.1  Q741W4  284 aa hypothetical protein 0.0032 ●●●○○ -2.73 -2.72807037720727
Vibrio parahaemolyticus RIMD 2210633  VP_2561  BAC60824.1  Q87LQ0  eno  433 aa enolase 0.0084 ●●●○○ -2.73 -2.72802706631293
Streptococcus pyogenes M1 5448  SP5448_05010  WP_010922337.1  407 aa aminoacyltransferase 0.012 ●●●○○ -2.73 -2.72748820332886
Streptococcus pyogenes M1 5448  SP5448_05685  WP_010922255.1  145 aa peptide-methionine (R)-S-oxide reductase MsrB 0.0072 ●●●○○ -2.73 -2.72556553033273
Vibrio parahaemolyticus RIMD 2210633  VP_0036  BAC58299.1  Q87TN3  83 aa conserved hypothetical protein 0.0085 ●●●○○ -2.72 -2.72399283495476
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3956  WP_000997824.1  E8XGX9  452 aa PTS galactitol transporter subunit IIC 6.9e-7 ●●●○○ -2.72 -2.72052506950283
Retrieved entries 901–1,000 out of 36,363 total in 9.6 ms (Link to these results)