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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_24160  ATI08533.1  429 aa 16S rRNA m5C967 methyltransferase 1.5e-37 ●●○○○ -1.18 -1.18042863739134
Escherichia coli M12  CO715_01285  ATI04485.1  541 aa isovaleryl-CoA dehydrogenase 9.6e-24 ●●○○○ -1.18 -1.18021999137709
Escherichia coli M12  CO715_02920  ATI04780.1  289 aa N-acetylmuramoyl-L-alanine amidase AmiA 6.1e-17 ●●○○○ -1.18 -1.18021999137709
Escherichia coli M12  CO715_06110  ATI05328.1  96 aa autoinducer 2-degrading protein LsrG 4.2e-17 ●●○○○ -1.18 -1.17980269934859
Escherichia coli M12  CO715_00410  ATI04329.1  136 aa type II toxin-antitoxin system HicB family antitoxin 3.6e-7 ●●○○○ -1.18 -1.17959405333435
Escherichia coli M12  CO715_07775  ATI05619.1  332 aa Fe3+ dicitrate ABC transporter permease 1.4e-6 ●●○○○ -1.18 -1.17917676130585
Escherichia coli M12  CO715_09450  ATI05917.1  254 aa alpha/beta hydrolase 3.4e-10 ●●○○○ -1.18 -1.1789681152916
Escherichia coli M12  CO715_11830  ATI06334.1  131 aa antitoxin 0.048 ●●○○○ -1.18 -1.17834217724885
Escherichia coli M12  CO715_15440  ATI06984.1  146 aa DUF805 domain-containing protein 0.00085 ●●○○○ -1.18 -1.17729894717761
Escherichia coli M12  CO715_10325  ATI06058.1  284 aa dimethyl sulfoxide reductase anchor subunit 1.6e-47 ●●○○○ -1.18 -1.17688165514911
Escherichia coli M12  CO715_24235  ATI08546.1  304 aa LysR family transcriptional regulator 6.1e-7 ●●○○○ -1.18 -1.17667300913486
Escherichia coli M12  CO715_03565  ATI04897.1  214 aa glutathione S-transferase 5.1e-5 ●●○○○ -1.18 -1.17646436312061
Escherichia coli M12  CO715_09080  ATI05857.1  239 aa nicotinamide riboside transporter PnuC 0.0074 ●●○○○ -1.18 -1.17646436312061
Escherichia coli M12  CO715_14195  ATI06755.1  296 aa iron-hydroxamate transporter substrate-binding subunit 1.3e-7 ●●○○○ -1.18 -1.17625571710636
Escherichia coli M12  CO715_03900  ATI04958.1  239 aa DNA-binding response regulator 9.0e-71 ●●○○○ -1.17 -1.17437790297812
Escherichia coli M12  CO715_07635  ATI05598.1  308 aa peptide ABC transporter ATP-binding protein 9.4e-11 ●●○○○ -1.17 -1.17437790297812
Escherichia coli M12  CO715_06970  ATI05478.1  71 aa holin 2.5e-40 ●●○○○ -1.17 -1.17354331892113
Escherichia coli M12  CO715_16815  ATI07234.1  142 aa hypothetical protein 0.00034 ●●○○○ -1.17 -1.17354331892113
Escherichia coli M12  CO715_20175  ATI07835.1  229 aa DNA-binding response regulator 0.0068 ●●○○○ -1.17 -1.17312602689263
Escherichia coli M12  CO715_21240  ATI08028.1  245 aa heme ABC transporter permease 3.8e-27 ●●○○○ -1.17 -1.17208279682139
Escherichia coli M12  CO715_15420  ATI06980.1  251 aa CDP-diacylglycerol pyrophosphatase 3.7e-19 ●●○○○ -1.17 -1.17187415080714
Escherichia coli M12  CO715_19535  ATI07719.1  891 aa aconitate hydratase AcnA 1.4e-53 ●●○○○ -1.17 -1.1704136287074
Escherichia coli M12  CO715_20160  ATI07832.1  457 aa proline-specific permease ProY 1.7e-66 ●●○○○ -1.17 -1.16790987653641
Escherichia coli M12  CO715_19030  ATI07624.1  222 aa DUF3313 domain-containing protein 2.2e-14 ●●○○○ -1.17 -1.16749258450791
Escherichia coli M12  CO715_13205  ATI06580.1  312 aa malate dehydrogenase 1.9e-13 ●●○○○ -1.17 -1.16686664646516
Escherichia coli M12  CO715_03540  ATI04892.1  257 aa histidine transport ATP-binding protein HisP 1.8e-12 ●●○○○ -1.17 -1.16644935443667
Escherichia coli M12  CO715_10440  ATI06079.1  433 aa two-component system sensor histidine kinase RstB 3.3e-51 ●●○○○ -1.16 -1.16352831023718
Escherichia coli M12  CO715_12375  ATI06430.1  110 aa tRNA-binding protein 2.0e-29 ●●○○○ -1.16 -1.16227643415169
Escherichia coli M12  CO715_21385  ATI08054.1  190 aa elongation factor P-like protein YeiP 1.0e-60 ●●○○○ -1.16 -1.16081591205195
Escherichia coli M12  CO715_12150  ATI06394.1  187 aa type II secretion system protein GspH 0.00031 ●●○○○ -1.16 -1.1606072660377
Escherichia coli M12  CO715_17440  ATI07345.1  147 aa cysteine desulfurase sulfur acceptor subunit CsdE 9.0e-14 ●●○○○ -1.16 -1.1597726819807
Escherichia coli M12  CO715_14740  ATI06859.1  127 aa aspartate 1-decarboxylase autocleavage activator PanM 4.6e-5 ●●○○○ -1.16 -1.15935538995221
Escherichia coli M12  CO715_13885  ATI06701.1  321 aa EamA/RhaT family transporter 5.5e-13 ●●○○○ -1.16 -1.15872945190946
Escherichia coli M12  CO715_06435  ATI05384.1  1247 aa nitrate reductase subunit alpha 7.2e-76 ●●○○○ -1.16 -1.15810351386671
Escherichia coli M12  CO715_09925  ATI05999.1  318 aa Fe2+-enterobactin ABC transporter substrate-binding protein 2.7e-7 ●●○○○ -1.16 -1.15747757582397
Escherichia coli M12  CO715_10800  ATI06142.1  470 aa pyruvate kinase 0.00052 ●●○○○ -1.16 -1.15643434575272
Escherichia coli M12  CO715_04350  ATI05044.1  458 aa two-component system sensor histidine kinase ZraS 1.5e-47 ●●○○○ -1.16 -1.15601705372422
Escherichia coli M12  CO715_06710  ATI05433.1  513 aa Na+/H+ antiporter NhaB 4.7e-20 ●●○○○ -1.16 -1.15539111568148
Escherichia coli M12  CO715_18225  ATI07483.1  314 aa Band 7 protein 1.4e-6 ●●○○○ -1.15 -1.15372194756749
Escherichia coli M12  CO715_15615  ATI07014.1  113 aa PTS fructose-like transporter subunit EIIB 1.3e-9 ●●○○○ -1.15 -1.15330465553899
Escherichia coli M12  CO715_05155  ATI05171.1  183 aa flagella biosynthesis regulatory protein FliZ 1.6e-14 ●●○○○ -1.15 -1.15267871749624
Escherichia coli M12  CO715_10365  ATI06065.1  111 aa acid shock protein 2.5e-14 ●●○○○ -1.15 -1.15184413343925
Escherichia coli M12  CO715_06520  ATI05400.1  277 aa protein-(glutamine-N5) methyltransferase, release factor-specific 0.029 ●●○○○ -1.15 -1.15184413343925
Escherichia coli M12  CO715_19655  ATI07739.1  168 aa ferritin-like domain-containing protein 1.8e-37 ●●○○○ -1.15 -1.151635487425
Escherichia coli M12  CO715_23045  ATI08350.1  167 aa protein FimG 2.6e-27 ●●○○○ -1.15 -1.14996631931101
Escherichia coli M12  CO715_10830  ATI06148.1  248 aa Fe-S cluster assembly ATPase SufC 4.2e-13 ●●○○○ -1.15 -1.14996631931101
Escherichia coli M12  CO715_22745  ATI08296.1  357 aa patatin family protein 1.5e-41 ●●○○○ -1.15 -1.14913173525401
Escherichia coli M12  CO715_19415  ATI07695.1  461 aa APC family permease 2.5e-20 ●●○○○ -1.15 -1.14892308923976
Escherichia coli M12  CO715_14845  ATI06878.1  231 aa pirin family protein 3.7e-28 ●●○○○ -1.15 -1.14808850518277
Escherichia coli M12  CO715_10380  ATI06068.1  109 aa spermidine export protein MdtI 1.8e-5 ●●○○○ -1.15 -1.14767121315427
Escherichia coli M12  CO715_17395  ATI07337.1  591 aa L-fucose isomerase 3.2e-6 ●●○○○ -1.15 -1.14683662909727
Escherichia coli M12  CO715_20385  ATI07874.1  179 aa DUF2058 domain-containing protein 4.0e-40 ●●○○○ -1.15 -1.14579339902603
Escherichia coli M12  CO715_01150  ATI08701.1  139 aa D-ribose pyranase 2.8e-28 ●●○○○ -1.15 -1.14537610699753
Escherichia coli M12  CO715_09455  ATI08772.1  97 aa LexA regulated protein 7.2e-15 ●●○○○ -1.14 -1.14099454069831
Escherichia coli M12  CO715_06600  ATI05413.1  472 aa dihydroxyacetone kinase subunit DhaM 8.4e-19 ●●○○○ -1.14 -1.13953401859856
Escherichia coli M12  CO715_03050  ATI04806.1  308 aa LysR family transcriptional regulator 2.2e-14 ●●○○○ -1.14 -1.13911672657007
Escherichia coli M12  CO715_00055  ATI04266.1  107 aa iron-sulfur cluster assembly accessory protein 0.0013 ●●○○○ -1.14 -1.13890808055582
Escherichia coli M12  CO715_10295  ATI06055.1  186 aa spermidine acetyltransferase 2.2e-36 ●●○○○ -1.14 -1.13869943454157
Escherichia coli M12  CO715_20025  ATI07806.1  454 aa MFS transporter 1.3e-5 ●●○○○ -1.14 -1.13849078852732
Escherichia coli M12  CO715_07555  ATI05583.1  418 aa leucine-rich repeat domain-containing protein 2.6e-73 ●●○○○ -1.14 -1.13807349649882
Escherichia coli M12  CO715_04635  ATI05085.1  156 aa very short patch repair endonuclease 0.0095 ●●○○○ -1.14 -1.13640432838483
Escherichia coli M12  CO715_10940  ATI06168.1  548 aa cyclohexanecarboxylate-CoA ligase 1.2e-145 ●●○○○ -1.14 -1.13536109831359
Escherichia coli M12  CO715_10260  ATI06048.1  431 aa site-specific integrase 3.8e-119 ●●○○○ -1.13 -1.13473516027084
Escherichia coli M12  CO715_19325  ATI07678.1  242 aa murein peptide amidase A 1.8e-25 ●●○○○ -1.13 -1.13473516027084
Escherichia coli M12  CO715_18100  ATI07460.1  331 aa methylmalonyl Co-A mutase-associated GTPase MeaB 0.0019 ●●○○○ -1.13 -1.13306599215685
Escherichia coli M12  CO715_18595  ATI07548.1  211 aa 3-hexulose-6-phosphate synthase 2.8e-16 ●●○○○ -1.13 -1.1328573461426
Escherichia coli M12  CO715_10725  ATI06130.1  382 aa cyclopropane-fatty-acyl-phospholipid synthase 1.2e-5 ●●○○○ -1.13 -1.13223140809985
Escherichia coli M12  CO715_05340  ATI05202.1  286 aa protein-glutamate O-methyltransferase CheR 0.00027 ●●○○○ -1.13 -1.1320227620856
Escherichia coli M12  CO715_05660  ATI05257.1  75 aa AlpA family phage regulatory protein 5.7e-15 ●●○○○ -1.13 -1.13118817802861
Escherichia coli M12  CO715_11085  ATI06197.1  267 aa hypothetical protein 1.7e-18 ●●○○○ -1.13 -1.13077088600011
Escherichia coli M12  CO715_20610  ATI07914.1  375 aa iron uptake system protein EfeO 2.9e-10 ●●○○○ -1.13 -1.13056223998586
Escherichia coli M12  CO715_22885  ATI08320.1  716 aa carbon starvation protein A 2.2e-8 ●●○○○ -1.13 -1.13056223998586
Escherichia coli M12  CO715_22315  ATI08225.1  67 aa LysR family transcriptional regulator 2.9e-5 ●●○○○ -1.13 -1.12972765592887
Escherichia coli M12  CO715_19475  ATI07707.1  644 aa exoribonuclease 2 4.5e-64 ●●○○○ -1.13 -1.12931036390037
Escherichia coli M12  CO715_05555  ATI05241.1  686 aa oligopeptidase B 1.9e-15 ●●○○○ -1.13 -1.12931036390037
Escherichia coli M12  CO715_19715  ATI07747.1  264 aa hypothetical protein 1.1e-24 ●●○○○ -1.13 -1.12826713382913
Escherichia coli M12  CO715_23940  ATI08491.1  252 aa DeoR/GlpR family transcriptional regulator 0.00033 ●●○○○ -1.13 -1.12784984180063
Escherichia coli M12  CO715_20875  ATI07962.1  251 aa flagellar biosynthesis protein FlgF 5.7e-125 ●●○○○ -1.13 -1.12638931970089
Escherichia coli M12  CO715_19115  ATI07640.1  266 aa DUF218 domain-containing protein 1.8e-6 ●●○○○ -1.13 -1.12638931970089
Escherichia coli M12  CO715_00315  ATI04315.1  444 aa transcriptional regulator 0.00058 ●●○○○ -1.13 -1.12555473564389
Escherichia coli M12  CO715_03710  ATI04926.1  402 aa deubiquitinase 5.0e-39 ●●○○○ -1.13 -1.12534608962964
Escherichia coli M12  CO715_19335  ATI07680.1  168 aa 2-Cys peroxiredoxin 6.6e-20 ●●○○○ -1.12 -1.12492879760114
Escherichia coli M12  CO715_09740  ATI05965.1  37 aa DNA-binding protein 0.0011 ●●○○○ -1.12 -1.1230509834729
Escherichia coli M12  CO715_08765  ATI05797.1  219 aa glutamine ABC transporter permease 0.025 ●●○○○ -1.12 -1.1230509834729
Escherichia coli M12  CO715_21355  ATI08048.1  604 aa ABC transporter substrate-binding protein 7.9e-19 ●●○○○ -1.12 -1.12284233745865
Escherichia coli M12  CO715_10340  ATI06061.1  231 aa dethiobiotin synthase 0.0079 ●●○○○ -1.12 -1.12221639941591
Escherichia coli M12  CO715_07200  ATI05522.1  285 aa spermidine/putrescine ABC transporter permease PotB 1.2e-28 ●●○○○ -1.12 -1.12179910738741
Escherichia coli M12  CO715_10890  ATI06158.1  288 aa quinate/shikimate dehydrogenase 8.1e-16 ●●○○○ -1.12 -1.11825212514518
Escherichia coli M12  CO715_18805  ATI07585.1  386 aa bifunctional chorismate mutase/prephenate dehydratase 2.1e-66 ●●○○○ -1.12 -1.11658295703119
Escherichia coli M12  CO715_13155  ATI06571.1  212 aa stringent starvation protein A 3.7e-11 ●●○○○ -1.12 -1.11616566500269
Escherichia coli M12  CO715_22165  ATI08197.1  421 aa ATP-dependent RNA helicase RhlB 6.0e-58 ●●○○○ -1.11 -1.1144964968887
Escherichia coli M12  CO715_23830  ATI08472.1  50 aa protein HokE 1.3e-5 ●●○○○ -1.11 -1.1144964968887
Escherichia coli M12  CO715_06740  ATI05438.1  219 aa isomerase/hydrolase 7.7e-9 ●●○○○ -1.11 -1.11428785087445
Escherichia coli M12  CO715_19730  ATI07750.1  550 aa bifunctional UDP-sugar hydrolase/5'-nucleotidase 1.7e-17 ●●○○○ -1.11 -1.11366191283171
Escherichia coli M12  CO715_19410  ATI07694.1  472 aa gamma-glutamylputrescine synthetase PuuA 3.4e-52 ●●○○○ -1.11 -1.11282732877471
Escherichia coli M12  CO715_00610  ATI04368.1  232 aa autotransporter outer membrane beta-barrel domain-containing protein 7.2e-27 ●●○○○ -1.11 -1.11241003674621
Escherichia coli M12  CO715_18325  ATI07501.1  234 aa YggS family pyridoxal phosphate enzyme 3.1e-6 ●●○○○ -1.11 -1.11220139073196
Escherichia coli M12  CO715_22310  ATI08224.1  195 aa cysteine/O-acetylserine transporter 0.008 ●●○○○ -1.11 -1.11157545268922
Escherichia coli M12  CO715_14700  ATI06851.1  89 aa hypothetical protein 1.9e-5 ●●○○○ -1.11 -1.11053222261797
Escherichia coli M12  CO715_05170  ATI05174.1  222 aa amino acid ABC transporter permease 0.0003 ●●○○○ -1.11 -1.11053222261797
Retrieved entries 901–1,000 out of 3,550 total in 48.9 ms (Link to these results)