Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Serratia marcescens Strain UMH9  BVG96_22245  ASM00163.1  432 aa adenylosuccinate synthase 1.3e-7 ●●●●● -4.07 -4.06937826154029
Mycobacterium avium subsp. paratuberculosis K10  MAP_1260  AAS03577.1  Q740T2  fadD11  606 aa FadD11_1 3.3e-5 ●●●●● -4.07 -4.06848664537763
Serratia marcescens Strain UMH9  BVG96_21325  ASM00001.1  303 aa tyrosine recombinase XerC 1.1e-5 ●●●●● -4.07 -4.06738186689728
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3017  WP_000922300.1  E8XL06  sptP  543 aa SPI-1 type III secretion system effector GTPase-activating protein SptP 4.1e-10 ●●●●● -4.06 -4.06408700276066
Streptococcus pyogenes M1 5448  SP5448_02790  WP_010922550.1  171 aa DUF1273 domain-containing protein 6.7e-5 ●●●●● -4.06 -4.06374593563894
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0070  WP_001126305.1  E8XG89  carB  1075 aa carbamoyl-phosphate synthase large subunit 4.8e-10 ●●●●● -4.06 -4.05899257830388
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4135  AIK82681.1  410 aa serA <1e-323 ●●●●● -4.06 -4.05861779133859
Vibrio parahaemolyticus RIMD 2210633  VPA_1360  BAC62703.1  Q87GF6  205 aa hypothetical protein 0.00013 ●●●●● -4.05 -4.05490413570304
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2495  AIK81092.1  466 aa leuC <1e-323 ●●●●● -4.05 -4.05285378708489
Acinetobacter baumannii ATCC 17978  A1S_2283  ABO12706.2  302 aa putative inorganic polyphosphate/ATP-NAD kinase 4.7e-67 ●●●●● -4.05 -4.0522026856651
Vibrio parahaemolyticus RIMD 2210633  VPA_1343  BAC62686.1  Q87GH3  97 aa hypothetical protein 0.00014 ●●●●● -4.05 -4.04872071231497
Serratia marcescens Strain UMH9  BVG96_19175  ASL99616.1  502 aa glycerol-3-phosphate dehydrogenase 2.8e-5 ●●●●● -4.04 -4.04396854626926
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2628  NP_232256.1  Q9KNV2  aroB  366 aa 3-dehydroquinate synthase 5.3e-8 ●●●●● -4.04 -4.04254408519615
Vibrio parahaemolyticus RIMD 2210633  VP_2744  BAC61007.1  Q87L68  aroB  366 aa 3-dehydroquinate synthase 0.0001 ●●●●● -4.03 -4.03483939794543
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2773  WP_001235094.1  E8XIC8  clpB  857 aa ATP-dependent chaperone ClpB 2.7e-9 ●●●●● -4.03 -4.03339080754162
Serratia marcescens Strain UMH9  BVG96_21250  ASL99989.1  246 aa lipopolysaccharide N-acetylmannosaminouronosyltransferase 1.8e-5 ●●●●● -4.03 -4.02561879875283
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4701  WP_000864857.1  E8XCE3  202 aa DUF1062 domain-containing protein 4.7e-30 ●●●●● -4.02 -4.02489429625233
Vibrio parahaemolyticus RIMD 2210633  VPA_1339  BAC62682.1  Q87GH7  487 aa putative type III secretion system EscC protein 0.00015 ●●●●● -4.02 -4.02427772548101
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1349  CBW17445.1  A0A0H3NB84  ssaN  433 aa Type III secretion ATP synthase 1.0e-16 ●●●●● -4.02 -4.02098092270892
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1343  CBW17439.1  A0A0H3NG97  ssaJ  249 aa Type III secretion system apparatus 1.0e-16 ●●●●● -4.02 -4.01685405946589
Acinetobacter baumannii ATCC 17978  A1S_0457  ABO10912.2  169 aa dihydrofolate reductase 2.1e-34 ●●●●● -4.01 -4.01055865850499
Serratia marcescens Strain UMH9  BVG96_22840  ASM00271.1  149 aa DNA polymerase III subunit chi 0.0022 ●●●●● -4.01 -4.00638545436557
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4629  WP_000736098.1  E8XBI5  340 aa D-chiro-inositol-2-dehydrogenase IolG2 4.7e-61 ●●●●● -4.01 -4.00520529854997
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4285  WP_000398248.1  E8XKH0  metL  239 aa mechanosensitive ion channel 6.1e-26 ●●●●● -4 -4.00432061528077
Vibrio parahaemolyticus RIMD 2210633  VP_2349  BAC60612.1  Q87MA8  nqrC  261 aa sodium-translocating NADH-quinone reductase, subunit C 0.00012 ●●●●● -4 -4.00282429196122
Acinetobacter baumannii ATCC 17978  A1S_2742  ABO13155.1  776 aa valyl-tRNA synthetase 1.2e-26 ●●●●● -4 -4.00185533109759
Vibrio parahaemolyticus RIMD 2210633  VP_3036  BAC61299.1  Q87KE1  purE  161 aa phosphoribosylaminoimidazole carboxylase, catalytic subunit 0.00012 ●●●●● -4 -4.0014722305726
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0291  NP_232687.1  H9L4R7  320 aa site-specific recombinase IntI4 3.4e-7 ●●●●● -4 -4.0007426896147
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1352  CBW17448.1  A0A0H3NB13  ssaQ  322 aa Type III secretion system protein 8.2e-18 ●●●●○ -4 -3.99864130147445
Mycobacterium avium subsp. paratuberculosis K10  MAP_1527c  AAS03844.1  Q73ZS4  172 aa hypothetical protein 4.4e-5 ●●●●○ -4 -3.99840004656795
Haemophilus influenzae Rd KW20  HI_0846  NP_439006.1  P31810  dsbA  205 aa oxidoreductase 0.00011 ●●●●○ -4 -3.99645412257898
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4696  WP_000233467.1  E8XCD8  104 aa hypothetical protein 1.1e-44 ●●●●○ -3.99 -3.9926239641137
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0328  WP_001226198.1  E8XJL6  dinP  351 aa DNA polymerase IV 6.2e-30 ●●●●○ -3.99 -3.99057320637364
Serratia marcescens Strain UMH9  BVG96_04495  ASM00473.1  298 aa UTP--glucose-1-phosphate uridylyltransferase 0.00021 ●●●●○ -3.99 -3.99023907143094
Vibrio parahaemolyticus RIMD 2210633  VPA_1341  BAC62684.1  Q87GH5  227 aa putative Spa29, component of the Mxi-Spa secretion machinery 0.00017 ●●●●○ -3.99 -3.98953027190144
Mycobacterium avium subsp. paratuberculosis K10  MAP_1047  AAS03364.1  Q741P2  relA  788 aa RelA 4.8e-5 ●●●●○ -3.98 -3.97905701918241
Vibrio parahaemolyticus RIMD 2210633  VP_2190  BAC60453.1  Q87MP1  truA  264 aa tRNA pseudouridine synthase A 0.00013 ●●●●○ -3.98 -3.97551880184839
Vibrio parahaemolyticus RIMD 2210633  VP_2211  BAC60474.1  Q87MM0  242 aa hypothetical protein 0.00013 ●●●●○ -3.97 -3.97407679150473
Vibrio parahaemolyticus RIMD 2210633  VP_2347  BAC60610.1  Q87MB0  nqrE  198 aa sodium-translocating NADH-quinone reductase, subunit E 0.00013 ●●●●○ -3.97 -3.96872677278926
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3945  CBW20036.1  A0A0H3NUM9  dsbA  207 aa thiol:disulfide interchange protein 1.2e-15 ●●●●○ -3.97 -3.96842712480531
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3142  AIK81714.1  259 aa twin arginine-targeting protein translocase TatC <1e-323 ●●●●○ -3.96 -3.96389695647803
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4243  WP_001077320.1  E8XKC8  fieF  300 aa cation-efflux pump FieF 2.1e-29 ●●●●○ -3.96 -3.95898855454464
Haemophilus influenzae Rd KW20  HI_1193  NP_439349.1  P54689  ilvE  343 aa branched-chain amino acid aminotransferase 0.00013 ●●●●○ -3.96 -3.95837948781027
Mycobacterium avium subsp. paratuberculosis K10  MAP_0339c  AAS02656.1  Q744K2  697 aa hypothetical protein 5.3e-5 ●●●●○ -3.95 -3.95423172915175
Vibrio parahaemolyticus RIMD 2210633  VP_2981  BAC61244.1  Q87KJ6  xerC  310 aa integrase/recombinase XerC 0.00014 ●●●●○ -3.95 -3.95411507930019
Escherichia coli M12  CO715_05005  ATI05147.1  203 aa bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 6.6e-6 ●●●●○ -3.95 -3.95270822871596
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0960  WP_000642539.1  E8XCT0  focA  285 aa formate transporter FocA 7.3e-9 ●●●●○ -3.95 -3.94985536548292
Haemophilus influenzae Rd KW20  HI_0221  NP_438392.1  P44334  guaB  488 aa inosine 5'-monophosphate dehydrogenase 0.00014 ●●●●○ -3.95 -3.94541740851075
Vibrio parahaemolyticus RIMD 2210633  VP_0424  BAC58687.1  Q87SJ9  hldE  476 aa ADP-heptose synthase 0.00015 ●●●●○ -3.94 -3.94378396736436
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3551  WP_001085725.1  E8XD94  envR  220 aa acrEF/envCD operon transcriptional regulator 1.4e-9 ●●●●○ -3.94 -3.93874074408071
Acinetobacter baumannii ATCC 17978  A1S_3245  ABO13635.2  A3M9P1  hisF  252 aa imidazole glycerol phosphate synthase cyclase subunit 5.5e-32 ●●●●○ -3.94 -3.93848449124718
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4631  WP_001019386.1  E8XBI7  271 aa 2-keto-myo-inositol isomerase IolI2 1.4e-25 ●●●●○ -3.94 -3.93787180591458
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0903  NP_233288.1  Q9KL45  377 aa hypothetical protein 1.5e-9 ●●●●○ -3.93 -3.93452762578224
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1548  AIK80168.1  412 aa 3-phosphoshikimate 1-carboxyvinyltransferase 4.9e-7 ●●●●○ -3.93 -3.93173354643981
Haemophilus influenzae Rd KW20  HI_0693  NP_438853.1  P26093  hel  274 aa lipoprotein E 0.00015 ●●●●○ -3.93 -3.92791612443042
Acinetobacter baumannii ATCC 17978  A1S_0476  ABO10931.2  201 aa ATP-dependent Clp protease proteolytic subunit 3.4e-32 ●●●●○ -3.91 -3.91330384385776
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3791  WP_001205771.1  E8XFD5  yhjS  523 aa cellulose biosynthesis protein BcsE 1.9e-18 ●●●●○ -3.91 -3.91105744254589
Mycobacterium avium subsp. paratuberculosis K10  MAP_0675  AAS02992.1  Q743B0  318 aa hypothetical protein 6.3e-5 ●●●●○ -3.91 -3.91065791365897
Haemophilus influenzae Rd KW20  HI_0314  NP_438480.1  P44633  ruvC  190 aa Holliday junction resolvase 0.00016 ●●●●○ -3.91 -3.90567801680205
Acinetobacter baumannii ATCC 17978  A1S_3103  ABO13500.2  276 aa toluene tolerance efflux transporter 1.5e-19 ●●●●○ -3.9 -3.90447867839348
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3205  AIK81773.1  616 aa dihydroxy-acid dehydratase <1e-323 ●●●●○ -3.9 -3.90415881208498
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4107  WP_000183621.1  E8XIN9  wecG  246 aa lipopolysaccharide N-acetylmannosaminouronosyltransferase 1.4e-9 ●●●●○ -3.89 -3.89366902983641
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3064  CBW19163.1  A0A0H3NRQ2  yqgD  99 aa hypothetical inner membrane protein 6.6e-13 ●●●●○ -3.89 -3.88753401461009
Vibrio parahaemolyticus RIMD 2210633  VPA_1338  BAC62681.1  Q87GH8  420 aa putative ATPase YscN 0.00026 ●●●●○ -3.89 -3.88515337107752
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3299  WP_001081721.1  E8XAJ9  hybA  328 aa hydrogenase 2 operon protein HybA 1.1e-8 ●●●●○ -3.88 -3.88362564513113
Acinetobacter baumannii ATCC 17978  A1S_0999  ABO11431.1  480 aa putative signal peptide 1.0e-47 ●●●●○ -3.88 -3.88176408422515
Acinetobacter baumannii ATCC 17978  A1S_3425  ABO13814.2  A3MA70  purC  239 aa phosphoribosylaminoimidazole-succinocarboxamide synthase 2.4e-32 ●●●●○ -3.88 -3.87909830339656
Vibrio parahaemolyticus RIMD 2210633  VP_0793  BAC59056.1  Q87RK1  169 aa PTS system, glucose-specific IIA component 0.00019 ●●●●○ -3.88 -3.87891594334117
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3918  WP_000016748.1  E8XGU4  recG  693 aa ATP-dependent DNA helicase RecG 2.5e-9 ●●●●○ -3.88 -3.87502990578126
Vibrio parahaemolyticus RIMD 2210633  VPA_0702  BAC62045.1  Q87IA4  37 aa hypothetical protein 0.00027 ●●●●○ -3.87 -3.87428238229951
Vibrio parahaemolyticus RIMD 2210633  VPA_1350  BAC62693.1  Q87GG6  217 aa hypothetical protein 0.00027 ●●●●○ -3.87 -3.87314580852887
Acinetobacter baumannii ATCC 17978  A1S_2598  ABO13015.2  204 aa putative RNA polymerase sigma factor 1.7e-12 ●●●●○ -3.87 -3.86890159539523
Vibrio parahaemolyticus RIMD 2210633  VP_2442  BAC60705.1  Q87M16  132 aa DNA polymerase III, psi subunit 0.0002 ●●●●○ -3.87 -3.86813842559443
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2294  NP_231925.1  Q9KPS2  nqrB  427 aa Na(+)-translocating NADH-quinone reductase subunit B 1.8e-15 ●●●●○ -3.87 -3.86627990375558
Vibrio parahaemolyticus RIMD 2210633  VPA_1311  BAC62654.1  Q87GK4  31 aa hypothetical protein 0.00028 ●●●●○ -3.87 -3.86573230381247
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2169  WP_000009017.1  E8XC38  rfbM  479 aa mannose-1-phosphate guanylyltransferase RfbM 6.1e-22 ●●●●○ -3.86 -3.86087015007892
Mycobacterium avium subsp. paratuberculosis K10  MAP_2683  AAS05000.1  Q73WH7  402 aa hypothetical protein 7.7e-5 ●●●●○ -3.86 -3.85849665718247
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1673  WP_001574288.1  E8XJZ0  fnr  264 aa fumarate/nitrate reduction transcriptional regulator Fnr 2.0e-9 ●●●●○ -3.86 -3.85823372685163
Haemophilus influenzae Rd KW20  HI_0141  NP_438310.1  P44538  nagB  270 aa glucosamine-6-phosphate deaminase 0.0002 ●●●●○ -3.85 -3.85058021706103
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3916  WP_000280481.1  E8XGU2  spoT  703 aa bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 3.1e-9 ●●●●○ -3.85 -3.85024165814973
Vibrio parahaemolyticus RIMD 2210633  VP_0444  BAC58707.1  Q87SH9  211 aa stringent starvation protein A 0.00021 ●●●●○ -3.85 -3.84749714089466
Salmonella enterica Serovar Typhimurium SL1344  SL1344_1168  CBW17264.1  E1WFA0  phoQ  487 aa sensor protein PhoQ, regulator of virulence determinants 1.6e-16 ●●●●○ -3.85 -3.84649438772514
Vibrio parahaemolyticus RIMD 2210633  VP_0230  BAC58493.1  Q87T40  412 aa putative glycosyltransferase 0.00021 ●●●●○ -3.85 -3.8455559793708
Vibrio parahaemolyticus RIMD 2210633  VP_2592  BAC60855.1  Q87LL9  rpiA  218 aa ribose-5-phosphate isomerase 0.00021 ●●●●○ -3.84 -3.84431843425413
Salmonella enterica Serovar Typhimurium SL1344  SL1344_2331  CBW18433.1  A0A0H3NDU2  purF  505 aa amidophosphoribosyltransferase 9.1e-20 ●●●●○ -3.84 -3.84364314310318
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2828  WP_001274643.1  E8XII2  539 aa phage tail protein 4.0e-26 ●●●●○ -3.84 -3.83820208373748
Serratia marcescens Strain UMH9  BVG96_04530  ASL96912.1  412 aa PST family polysaccharide transporter 0.0006 ●●●●○ -3.83 -3.83165083990592
Acinetobacter baumannii ATCC 17978  A1S_0061  ABO10556.2  210 aa putative UDP-galactose phosphate transferase 7.4e-35 ●●●●○ -3.83 -3.82797021712493
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2424  WP_000386728.1  E8XEH0  nuoB  220 aa NADH-quinone oxidoreductase subunit B 1.9e-8 ●●●●○ -3.82 -3.82392225727817
Vibrio parahaemolyticus RIMD 2210633  VP_1945  BAC60208.1  Q87NC3  214 aa transcriptional regulator, LuxR family 0.00024 ●●●●○ -3.82 -3.8171482449427
Vibrio parahaemolyticus RIMD 2210633  VP_0654  BAC58917.1  Q87RX2  dnaJ  381 aa DnaJ protein 0.00024 ●●●●○ -3.81 -3.81215071675726
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2392  WP_000879248.1  E8XED8  ais  201 aa lipopolysaccharide core heptose(II)-phosphate phosphatase 6.1e-29 ●●●●○ -3.8 -3.80377028686558
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2915  WP_001521746.1  E8XK21  virK  65 aa hypothetical protein 3.4e-18 ●●●●○ -3.8 -3.80262804634392
Haemophilus influenzae Rd KW20  HI_0334  NP_438498.1  P44644  relA  743 aa GTP pyrophosphokinase 0.00025 ●●●●○ -3.8 -3.80127404676561
Vibrio parahaemolyticus RIMD 2210633  VP_0617  BAC58880.1  Q87S07  guaA  517 aa GMP synthase 0.00026 ●●●●○ -3.8 -3.79809043243665
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0545  WP_000484503.1  E8X8B1  ybbY  432 aa uracil/xanthine transporter 1.5e-59 ●●●●○ -3.79 -3.79435663046311
Serratia marcescens Strain UMH9  BVG96_04575  ASM00474.1  464 aa undecaprenyl-phosphate glucose phosphotransferase 1.4e-8 ●●●●○ -3.79 -3.79369032472354
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3825  WP_000702452.1  E8XFW8  155 aa GNAT family N-acetyltransferase 6.6e-20 ●●●●○ -3.79 -3.79279517988286
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0248  NP_229905.1  Q9KVA1  80 aa acyl carrier protein 8.7e-15 ●●●●○ -3.79 -3.78934291249925
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4096  WP_000771937.1  E8XIM8  rfe  367 aa UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase 3.3e-24 ●●●●○ -3.79 -3.78906927071998
Retrieved entries 301–400 out of 36,363 total in 566.6 ms (Link to these results)