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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_05065  ATI05157.1  352 aa YeeE/YedE family protein 1.1e-132 ●○○○○ -0.99 -0.98993482638213
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0663  NP_230312.1  365 aa peptide chain release factor 2 3.8e-9 ●○○○○ -0.99 -0.989571042437967
Acinetobacter baumannii ATCC 17978  A1S_0049  ABO10544.2  728 aa protein tyrosine kinase 0.047 ●○○○○ -0.99 -0.989025987258829
Porphyromonas gingivalis ATCC 33277  PGN_1126  WP_012458045.1  B2RJV0  141 aa translesion error-prone DNA polymerase V autoproteolytic subunit 2.2e-16 ●○○○○ -0.99 -0.989015621973325
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2186  WP_000770904.1  E8XCT9  wcaK  426 aa colanic acid biosynthesis pyruvyl transferase WcaK 0.039 ●○○○○ -0.99 -0.988855518773109
Escherichia coli M12  CO715_11535  ATI06282.1  454 aa L-serine ammonia-lyase 1.9e-150 ●○○○○ -0.99 -0.987848366239642
Escherichia coli CFT073  c2478  AAN80937.1  Q8FGA4  cobS  259 aa Cobalamin [5'-phosphate] synthase 0.02 ●○○○○ -0.99 -0.987469748599242
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3480  AIK82036.1  566 aa acyltransferase family protein <1e-323 ●○○○○ -0.99 -0.986858504858952
Escherichia coli M12  CO715_05805  ATI05282.1  131 aa phage tail protein 0.023 ●○○○○ -0.99 -0.985761906097153
Porphyromonas gingivalis ATCC 33277  PGN_1347  WP_039417524.1  B2RKH1  816 aa TonB-dependent receptor <1e-323 ●○○○○ -0.99 -0.985156685453406
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1354  WP_000069340.1  E8XGF6  pps  792 aa phosphoenolpyruvate synthase 0.049 ●○○○○ -0.98 -0.984871149788768
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3183  AIK81751.1  416 aa polysaccharide biosynthesis family protein 1.6e-8 ●○○○○ -0.98 -0.984524320293708
Escherichia coli M12  CO715_00270  ATI04306.1  86 aa ferredoxin 5.2e-7 ●○○○○ -0.98 -0.981797631826425
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2098  WP_001669456.1  E8XB80  485 aa EmmdR/YeeO family multidrug/toxin efflux MATE transporter 0.0005 ●○○○○ -0.98 -0.981732266717694
Escherichia coli M12  CO715_04805  ATI05112.1  495 aa alpha-amylase 2.0e-15 ●○○○○ -0.98 -0.981588985812176
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2522  AIK81119.1  275 aa dnaJ domain protein <1e-323 ●○○○○ -0.98 -0.981282605576323
Escherichia coli M12  CO715_05520  ATI05235.1  392 aa formate-dependent phosphoribosylglycinamide formyltransferase 1.1e-33 ●○○○○ -0.98 -0.98075440175518
Escherichia coli M12  CO715_05310  ATI05198.1  295 aa flagellar motor stator protein MotA 0.00027 ●○○○○ -0.98 -0.980545755740932
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4277  AIK82823.1  338 aa galR transcriptional repressor GalR transcriptional dual regulator 8.0e-14 ●○○○○ -0.98 -0.979822889893516
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2356  AIK80953.1  118 aa putative regulator in colanic acid synthesis; interacts with RcsB <1e-323 ●○○○○ -0.98 -0.979493696628959
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0651  NP_233040.1  Q9KLU0  193 aa hypothetical protein 0.00072 ●○○○○ -0.98 -0.979473360123816
Escherichia coli M12  CO715_20220  ATI07842.1  225 aa hypothetical protein 1.8e-11 ●○○○○ -0.98 -0.97908523364119
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2209  WP_000042954.1  E8XCW2  996 aa diguanylate cyclase 1.2e-5 ●○○○○ -0.98 -0.97877100953496
Escherichia coli M12  CO715_13055  ATI06554.1  90 aa phosphocarrier protein NPr 0.00072 ●○○○○ -0.98 -0.978459295598443
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0467  WP_000973433.1  E8XKN4  bolA  105 aa transcriptional regulator BolA 0.042 ●○○○○ -0.98 -0.978265762529062
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4353  AIK82896.1  131 aa hypothetical protein <1e-323 ●○○○○ -0.98 -0.97813487626046
Escherichia coli M12  CO715_03115  ATI04813.1  412 aa divalent metal cation transporter 6.2e-48 ●○○○○ -0.98 -0.97720741951295
Escherichia coli M12  CO715_02395  ATI04684.1  269 aa formamidopyrimidine-DNA glycosylase 2.2e-17 ●○○○○ -0.98 -0.976998773498701
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0034  NP_232435.1  Q9KND1  290 aa hypothetical protein 1.7e-5 ●○○○○ -0.98 -0.976449367705002
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4602  WP_071527475.1  E8XAT0  77 aa hypothetical protein 0.0019 ●○○○○ -0.98 -0.975207014912804
Escherichia coli M12  CO715_17665  ATI07385.1  72 aa hypothetical protein 7.8e-5 ●○○○○ -0.98 -0.975120959370461
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3019  WP_000692254.1  E8XL08  86 aa hypothetical protein 0.00082 ●○○○○ -0.98 -0.975104510495635
Escherichia coli M12  CO715_09885  ATI05991.1  362 aa oxidoreductase 9.4e-112 ●○○○○ -0.97 -0.974912313356212
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0431  NP_230085.2  Q9KUT4  argR  156 aa arginine repressor ArgR 0.00026 ●○○○○ -0.97 -0.974731933497604
Escherichia coli M12  CO715_11320  ATI06241.1  278 aa ketose-bisphosphate aldolase 1.3e-37 ●○○○○ -0.97 -0.974703667341963
Acinetobacter baumannii ATCC 17978  A1S_0499  ABO10952.2  A3M208  rlmN  410 aa putative Fe-S-cluster redox enzyme 3.4e-9 ●○○○○ -0.97 -0.973428339122279
Acinetobacter baumannii ATCC 17978  A1S_2779  ABO13191.2  163 aa rod shape-determining protein 4.6e-8 ●○○○○ -0.97 -0.973213880055103
Escherichia coli M12  CO715_23505  ATI08415.1  120 aa hypothetical protein 1.5e-12 ●○○○○ -0.97 -0.973034499227972
Escherichia coli CFT073  c1853  AAN80316.1  A0A0H2V795  tehA  366 aa Tellurite resistance protein tehA 0.014 ●○○○○ -0.97 -0.972832484885002
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3285  AIK81846.1  309 aa formate dehydrogenase accessory protein FdhE <1e-323 ●○○○○ -0.97 -0.972443856350512
Acinetobacter baumannii ATCC 17978  A1S_1235  ABO11663.2  A3M419  cysS  473 aa cysteinyl-tRNA synthetase 6.8e-5 ●○○○○ -0.97 -0.97236213338276
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3685  WP_000729713.1  E8XEM1  86 aa type II toxin-antitoxin system RelB/DinJ family antitoxin 0.049 ●○○○○ -0.97 -0.97216297377017
Porphyromonas gingivalis ATCC 33277  PGN_0904  WP_043876361.1  B2RJ78  fimS  602 aa sensor histidine kinase 8.1e-15 ●○○○○ -0.97 -0.971525845303305
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2522  NP_232151.1  Q9KP54  332 aa hypothetical protein 1.9e-8 ●○○○○ -0.97 -0.971444789644352
Escherichia coli M12  CO715_14395  ATI06792.1  117 aa transcriptional regulator 1.1e-6 ●○○○○ -0.97 -0.971156685099733
Escherichia coli M12  CO715_08390  ATI05728.1  333 aa low-specificity L-threonine aldolase 3.4e-14 ●○○○○ -0.97 -0.970113455028489
Escherichia coli M12  CO715_09805  ATI05976.1  302 aa citrate (pro-3S)-lyase subunit beta 1.1e-6 ●○○○○ -0.97 -0.970113455028489
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0582  NP_232972.1  Q9KM07  160 aa hypothetical protein 0.00066 ●○○○○ -0.97 -0.969265029387798
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2510  AIK81107.1  281 aa araC 0.0026 ●○○○○ -0.97 -0.969086751204925
Escherichia coli M12  CO715_07210  ATI05524.1  348 aa spermidine/putrescine ABC transporter substrate-binding protein PotD 3.9e-214 ●○○○○ -0.97 -0.968235640900249
Salmonella enterica Serovar Typhimurium SL1344  SL1344_4240  CBW20326.1  A0A0H3NIL7  dcuR  239 aa two-component response regulator 0.049 ●○○○○ -0.97 -0.967573491993549
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2384  AIK80981.1  264 aa methionine aminopeptidase, type I 0.00056 ●○○○○ -0.97 -0.967101492042232
Escherichia coli M12  CO715_08210  ATI05698.1  760 aa formate acetyltransferase 1.8e-30 ●○○○○ -0.97 -0.965105950686516
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0910  WP_000644017.1  E8XCN1  495 aa sulfatase 1.2e-5 ●○○○○ -0.97 -0.965071183877899
Escherichia coli M12  CO715_20695  ATI07928.1  151 aa major curlin subunit CsgA 6.5e-70 ●○○○○ -0.96 -0.964688658658018
Escherichia coli M12  CO715_00380  ATI04326.1  270 aa 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase 2.1e-58 ●○○○○ -0.96 -0.964480012643769
Escherichia coli M12  CO715_22755  ATI08298.1  201 aa molecular chaperone OsmY 0.0041 ●○○○○ -0.96 -0.964480012643769
Acinetobacter baumannii ATCC 17978  A1S_1854  ABO12281.2  768 aa Cu2+-containing amine oxidase 1.7e-6 ●○○○○ -0.96 -0.963910664296104
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1212  AIK79835.1  179 aa intracellular septation protein A 4.2e-5 ●○○○○ -0.96 -0.963354555175817
Porphyromonas gingivalis ATCC 33277  PGN_1493  WP_012458315.1  B2RKW7  515 aa hypothetical protein 0.0025 ●○○○○ -0.96 -0.963255071117676
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3897  AIK82446.1  209 aa cyclic nucleotide-binding domain protein <1e-323 ●○○○○ -0.96 -0.962857601616783
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3860  WP_001062558.1  E8XG02  69 aa hypothetical protein 0.027 ●○○○○ -0.96 -0.962540754862711
Escherichia coli M12  CO715_14305  ATI06775.1  207 aa anaerobilin reductase 3.1e-18 ●○○○○ -0.96 -0.962393552501281
Escherichia coli M12  CO715_06285  ATI05362.1  931 aa insulinase family protein 1.1e-72 ●○○○○ -0.96 -0.961558968444285
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3193  AIK81761.1  109 aa thioredoxin <1e-323 ●○○○○ -0.96 -0.961449885955664
Escherichia coli M12  CO715_18620  ATI07553.1  173 aa PTS sorbitol transporter subunit IIC 5.4e-29 ●○○○○ -0.96 -0.960307092358792
Escherichia coli M12  CO715_03235  ATI04837.1  512 aa multidrug resistance protein EmrY 1.1e-71 ●○○○○ -0.96 -0.959889800330294
Escherichia coli M12  CO715_18200  ATI07479.1  321 aa fructose-bisphosphatase class II 3.3e-17 ●○○○○ -0.96 -0.959889800330294
Escherichia coli M12  CO715_12195  ATI06402.1  216 aa ABC transporter ATP-binding protein 2.9e-36 ●○○○○ -0.96 -0.959263862287548
Escherichia coli M12  CO715_06050  ATI05318.1  371 aa hypothetical protein 1.8e-57 ●○○○○ -0.96 -0.959055216273299
Escherichia coli M12  CO715_10425  ATI06076.1  240 aa dihydromonapterin reductase 4.8e-46 ●○○○○ -0.96 -0.95884657025905
Acinetobacter baumannii ATCC 17978  A1S_2640  ABO13057.1  802 aa putative oxidoreductase molybdopterin 3.3e-9 ●○○○○ -0.96 -0.958172594484798
Escherichia coli M12  CO715_21025  ATI07992.1  213 aa penicillin-binding protein activator LpoB 3.1e-198 ●○○○○ -0.96 -0.958011986202054
Acinetobacter baumannii ATCC 17978  A1S_2370  ABO12789.2  A3M795  hemE  357 aa uroporphyrinogen decarboxylase 0.036 ●○○○○ -0.96 -0.957870123927548
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2163  WP_000954848.1  E8XC32  hisI  203 aa bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.00042 ●○○○○ -0.96 -0.957435112169304
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1007  WP_014343823.1  E8XDH0  96 aa hypothetical protein 0.016 ●○○○○ -0.96 -0.957161639478537
Acinetobacter baumannii ATCC 17978  A1S_1069  ABO11500.1  A3M3K6  argG  187 aa argininosuccinate synthetase 3.0e-9 ●○○○○ -0.96 -0.955458257679581
Escherichia coli M12  CO715_23545  ATI08423.1  228 aa ABC transporter ATP-binding protein 4.5e-10 ●○○○○ -0.96 -0.955090942002571
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2983  AIK81568.1  252 aa hypothetical protein 1.0e-12 ●○○○○ -0.95 -0.954975034736963
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1469  WP_014343837.1  E8XI43  ydgJ  371 aa oxidoreductase 0.04 ●○○○○ -0.95 -0.95475784535841
Escherichia coli M12  CO715_24435  ATI08579.1  256 aa amidohydrolase 5.3e-9 ●○○○○ -0.95 -0.954465003959824
Acinetobacter baumannii ATCC 17978  A1S_2179  ABO12606.2  198 aa hypothetical protein 4.4e-5 ●○○○○ -0.95 -0.953596834227848
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2632  WP_000508279.1  E8XGL9  801 aa dimethyl sulfoxide reductase subunit A 0.00023 ●○○○○ -0.95 -0.953284757216813
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1600  NP_231240.1  Q9KRN6  229 aa hypothetical protein 4.3e-8 ●○○○○ -0.95 -0.95325501146268
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2593  AIK81190.1  440 aa thymidine phosphorylase <1e-323 ●○○○○ -0.95 -0.951697280153892
Escherichia coli M12  CO715_23675  ATI08444.1  289 aa hypothetical protein 1.9e-16 ●○○○○ -0.95 -0.950083437660598
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3271  WP_000712459.1  E8XAH1  579 aa arylsulfatase 0.0015 ●○○○○ -0.95 -0.949795609867654
Escherichia coli M12  CO715_05710  ATI05267.1  113 aa head decoration protein 7.7e-5 ●○○○○ -0.95 -0.948831561575105
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1898  NP_231532.1  Q9KQV0  672 aa methyl-accepting chemotaxis protein 6.4e-8 ●○○○○ -0.95 -0.948781653362877
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4065  WP_000224491.1  E8XIK6  rbsR  332 aa ribose operon transcriptional repressor RbsR 4.8e-5 ●○○○○ -0.95 -0.948451195970032
Escherichia coli M12  CO715_04415  ATI05050.1  247 aa adenosylcobinamide-GDP ribazoletransferase 3.6e-8 ●○○○○ -0.95 -0.948414269546607
Acinetobacter baumannii ATCC 17978  A1S_2435  ABO12853.2  382 aa D-ala-D-ala-carboxypeptidase; penicillin-binding protein 5 (precursor) 9.5e-9 ●○○○○ -0.95 -0.948184835697357
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2510  WP_000376347.1  E8XFM2  nupC  400 aa nucleoside permease NupC 1.5e-5 ●○○○○ -0.95 -0.947982042895286
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1314  NP_230958.1  Q9KSE3  487 aa transporter 3.8e-7 ●○○○○ -0.95 -0.94780082046044
Acinetobacter baumannii ATCC 17978  A1S_0862  ABO11294.2  150 aa putative membrane protein 0.0056 ●○○○○ -0.95 -0.947773203450146
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1871  WP_001207294.1  E8X9A7  yebS  427 aa paraquat-inducible protein A 1.9e-5 ●○○○○ -0.95 -0.94742452945915
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3658  AIK82213.1  295 aa ugpA <1e-323 ●○○○○ -0.95 -0.947259212829144
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2740  AIK81330.1  865 aa pglZ domain protein 2.2e-5 ●○○○○ -0.95 -0.94582770858952
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4080  AIK82626.1  360 aa hypothetical protein <1e-323 ●○○○○ -0.95 -0.945779845767583
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3532  AIK82088.1  161 aa putative electron transport protein HydN 4.2e-8 ●○○○○ -0.95 -0.945278893391205
Retrieved entries 4,201–4,300 out of 36,363 total in 7.7 ms (Link to these results)