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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_00700  ATI04381.1  500 aa signal transduction histidine-protein kinase/phosphatase UhpB 1.3e-13 ●○○○○ -0.82 -0.824269891068534
Escherichia coli M12  CO715_12995  ATI06542.1  260 aa phospholipid ABC transporter permease 4.5e-15 ●○○○○ -0.82 -0.823852599040037
Escherichia coli M12  CO715_10385  ATI06069.1  121 aa multidrug transporter subunit MdtJ 1.0e-29 ●○○○○ -0.82 -0.823435307011539
Escherichia coli M12  CO715_10945  ATI06169.1  792 aa phosphoenolpyruvate synthase 2.0e-26 ●○○○○ -0.82 -0.82322666099729
Escherichia coli M12  CO715_19025  ATI07623.1  403 aa BenE family transporter YdcO 6.3e-10 ●○○○○ -0.82 -0.822809368968792
Escherichia coli M12  CO715_14200  ATI06756.1  265 aa iron(3+)-hydroxamate import ATP-binding protein FhuC 0.00023 ●○○○○ -0.82 -0.821557492883299
Escherichia coli M12  CO715_07725  ATI05612.1  69 aa hypothetical protein 0.0011 ●○○○○ -0.82 -0.821348846869051
Escherichia coli M12  CO715_06200  ATI05346.1  339 aa aldo/keto reductase 0.00072 ●○○○○ -0.82 -0.820514262812055
Escherichia coli M12  CO715_11455  ATI06267.1  212 aa leucine efflux protein 3.4e-19 ●○○○○ -0.82 -0.820305616797806
Escherichia coli M12  CO715_21590  ATI08091.1  478 aa multidrug transporter permease 1.7e-24 ●○○○○ -0.82 -0.819262386726562
Escherichia coli M12  CO715_12290  ATI08796.1  278 aa L(+)-tartrate dehydratase subunit alpha 8.4e-9 ●○○○○ -0.82 -0.818636448683815
Escherichia coli M12  CO715_07770  ATI05618.1  300 aa Fe(3+)-dicitrate ABC transporter substrate-binding protein FecB 2.0e-7 ●○○○○ -0.82 -0.818427802669566
Escherichia coli M12  CO715_08060  ATI05669.1  400 aa nicotinate phosphoribosyltransferase 0.011 ●○○○○ -0.82 -0.815298112455834
Escherichia coli M12  CO715_10315  ATI08784.1  807 aa dimethyl sulfoxide reductase subunit A 6.2e-23 ●○○○○ -0.81 -0.81404623637034
Escherichia coli M12  CO715_03110  ATI04812.1  400 aa nucleoside permease NupC 2.9e-10 ●○○○○ -0.81 -0.813420298327594
Escherichia coli M12  CO715_11885  ATI06345.1  219 aa DedA family protein 1.6e-5 ●○○○○ -0.81 -0.813420298327594
Escherichia coli M12  CO715_13980  ATI06717.1  140 aa aminoacyl-tRNA hydrolase 0.034 ●○○○○ -0.81 -0.811959776227852
Escherichia coli M12  CO715_11360  ATI06249.1  284 aa aldo/keto reductase 0.00035 ●○○○○ -0.81 -0.80862143999987
Escherichia coli M12  CO715_10695  ATI06124.1  389 aa MFS transporter 2.2e-5 ●○○○○ -0.81 -0.806952271885879
Escherichia coli M12  CO715_22770  ATI08301.1  148 aa ribosomal-protein-alanine N-acetyltransferase RimI 0.0024 ●○○○○ -0.81 -0.805909041814635
Escherichia coli M12  CO715_01020  ATI04437.1  296 aa phosphate ABC transporter, permease protein PstA 1.5e-7 ●○○○○ -0.8 -0.804657165729142
Escherichia coli M12  CO715_12110  ATI06387.1  37 aa prepilin peptidase A domain protein 1.3e-5 ●○○○○ -0.8 -0.803822581672146
Escherichia coli M12  CO715_17850  ATI07415.1  310 aa carbamate kinase-like protein YqeA 7.0e-15 ●○○○○ -0.8 -0.803613935657897
Escherichia coli M12  CO715_06860  ATI05459.1  403 aa diguanylate phosphodiesterase 9.0e-99 ●○○○○ -0.8 -0.803196643629399
Escherichia coli M12  CO715_17475  ATI07350.1  608 aa exodeoxyribonuclease V subunit alpha 4.1e-20 ●○○○○ -0.8 -0.80131882950116
Escherichia coli M12  CO715_02655  ATI04732.1  487 aa beta-barrel assembly-enhancing protease 0.00017 ●○○○○ -0.8 -0.800901537472662
Escherichia coli M12  CO715_00375  ATI04325.1  400 aa 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD+ reductase component 2.1e-10 ●○○○○ -0.8 -0.799858307401418
Escherichia coli M12  CO715_18970  ATI07613.1  474 aa gamma-aminobutyraldehyde dehydrogenase 2.1e-20 ●○○○○ -0.8 -0.796937263201934
Escherichia coli M12  CO715_07670  ATI05605.1  460 aa diguanylate cyclase 1.8e-35 ●○○○○ -0.8 -0.795894033130689
Escherichia coli M12  CO715_21815  ATI08134.1  420 aa tagatose-bisphosphate aldolase subunit GatZ 4.9e-22 ●○○○○ -0.8 -0.795059449073694
Escherichia coli M12  CO715_14565  ATI06826.1  409 aa beta-ketoacyl-ACP synthase II 3.8e-30 ●○○○○ -0.79 -0.793807572988201
Escherichia coli M12  CO715_10910  ATI06162.1  303 aa AraC family transcriptional regulator 7.4e-36 ●○○○○ -0.79 -0.793598926973952
Escherichia coli M12  CO715_02980  ATI04792.1  291 aa sulfate ABC transporter permease subunit CysW 0.0073 ●○○○○ -0.79 -0.792972988931205
Escherichia coli M12  CO715_08845  ATI05811.1  332 aa transporter 1.2e-7 ●○○○○ -0.79 -0.792764342916956
Escherichia coli M12  CO715_08375  ATI05726.1  550 aa hydroxylamine reductase 2.1e-5 ●○○○○ -0.79 -0.792347050888459
Escherichia coli M12  CO715_22035  ATI08175.1  464 aa undecaprenyl-phosphate glucose phosphotransferase 1.5e-12 ●○○○○ -0.79 -0.79213840487421
Escherichia coli M12  CO715_08590  ATI05766.1  371 aa aldose dehydrogenase 2.8e-67 ●○○○○ -0.79 -0.790886528788717
Escherichia coli M12  CO715_10790  ATI06140.1  208 aa hypothetical protein 5.8e-44 ●○○○○ -0.79 -0.789426006688975
Escherichia coli M12  CO715_12445  ATI06444.1  227 aa hypothetical protein 2.8e-77 ●○○○○ -0.79 -0.788174130603481
Escherichia coli M12  CO715_10925  ATI06165.1  312 aa electron transfer flavoprotein subunit alpha 3.4e-15 ●○○○○ -0.79 -0.786922254517988
Escherichia coli M12  CO715_04740  ATI05104.1  228 aa flagellar assembly protein FliH 3.3e-18 ●○○○○ -0.79 -0.786713608503739
Escherichia coli M12  CO715_10420  ATI06075.1  460 aa arginine:ornithine antiporter 8.8e-21 ●○○○○ -0.78 -0.784627148361251
Escherichia coli M12  CO715_04910  ATI05131.1  162 aa ecotin 0.00024 ●○○○○ -0.78 -0.780454228076274
Escherichia coli M12  CO715_06865  ATI05460.1  243 aa helix-turn-helix-type transcriptional regulator 1.9e-5 ●○○○○ -0.77 -0.774612139677306
Escherichia coli M12  CO715_09650  ATI05948.1  235 aa DUF1266 domain-containing protein 9.0e-23 ●○○○○ -0.77 -0.77377755562031
Escherichia coli M12  CO715_22870  ATI08318.1  423 aa TRAP transporter large permease 4.9e-9 ●○○○○ -0.77 -0.772108387506319
Escherichia coli M12  CO715_20375  ATI07872.1  369 aa S-(hydroxymethyl)glutathione dehydrogenase 0.00028 ●○○○○ -0.77 -0.771482449463573
Escherichia coli M12  CO715_16400  ATI07156.1  254 aa hypothetical protein 1.6e-5 ●○○○○ -0.77 -0.770647865406577
Escherichia coli M12  CO715_02435  ATI04691.1  238 aa ribonuclease PH 0.00085 ●○○○○ -0.77 -0.767518175192844
Escherichia coli M12  CO715_24180  ATI08537.1  374 aa DNA-protecting protein DprA 9.3e-35 ●○○○○ -0.76 -0.762302024836623
Escherichia coli M12  CO715_13890  ATI06702.1  220 aa iron-sulfur cluster repair protein YtfE 6.5e-7 ●○○○○ -0.76 -0.761050148751129
Escherichia coli M12  CO715_15405  ATI06977.1  300 aa cation-efflux pump FieF 3.8e-18 ●○○○○ -0.76 -0.760215564694134
Escherichia coli M12  CO715_21445  ATI08065.1  362 aa kinase 1.6e-11 ●○○○○ -0.76 -0.760215564694134
Escherichia coli M12  CO715_13260  ATI06591.1  197 aa septum formation inhibitor Maf 2.8e-17 ●○○○○ -0.76 -0.760006918679885
Escherichia coli M12  CO715_01335  ATI04494.1  432 aa adenylosuccinate synthetase 8.1e-5 ●○○○○ -0.76 -0.759589626651388
Escherichia coli M12  CO715_03150  ATI04820.1  345 aa aminopeptidase 1.5e-31 ●○○○○ -0.76 -0.757503166508899
Escherichia coli M12  CO715_23575  ATI08428.1  271 aa HTH-type transcriptional repressor AllR 1.1e-19 ●○○○○ -0.75 -0.754790768323664
Escherichia coli M12  CO715_01540  ATI04529.1  112 aa divalent-cation tolerance protein CutA 0.043 ●○○○○ -0.75 -0.754582122309415
Escherichia coli M12  CO715_16795  ATI07230.1  390 aa multidrug export protein EmrA 1.9e-12 ●○○○○ -0.75 -0.754164830280917
Escherichia coli M12  CO715_12460  ATI06446.1  59 aa hypothetical protein 0.037 ●○○○○ -0.75 -0.752495662166926
Escherichia coli M12  CO715_15350  ATI06968.1  489 aa rhamnulokinase 1.8e-12 ●○○○○ -0.75 -0.752078370138429
Escherichia coli M12  CO715_15865  ATI07055.1  299 aa EamA family transporter 5.1e-5 ●○○○○ -0.75 -0.751661078109931
Escherichia coli M12  CO715_06455  ATI05388.1  598 aa nitrate/nitrite two-component system sensor histidine kinase NarX 6.5e-15 ●○○○○ -0.75 -0.749574617967442
Escherichia coli M12  CO715_20575  ATI07908.1  1320 aa trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase 8.7e-190 ●○○○○ -0.75 -0.748948679924695
Escherichia coli M12  CO715_09085  ATI05858.1  347 aa quinolinate synthase 2.6e-5 ●○○○○ -0.75 -0.748740033910447
Escherichia coli M12  CO715_03875  ATI04954.1  75 aa ferrous iron transporter A 4.8e-52 ●○○○○ -0.75 -0.745401697682465
Escherichia coli M12  CO715_03560  ATI04896.1  215 aa thiol:disulfide oxidoreductase 5.7e-9 ●○○○○ -0.74 -0.744358467611221
Escherichia coli M12  CO715_11155  ATI06210.1  191 aa protein Ves 2.5e-7 ●○○○○ -0.74 -0.744149821596972
Escherichia coli M12  CO715_01480  ATI04518.1  48 aa entericidin B 3.1e-17 ●○○○○ -0.74 -0.741228777397488
Escherichia coli M12  CO715_15435  ATI06983.1  199 aa DUF1454 domain-containing protein 2.7e-5 ●○○○○ -0.74 -0.737890441169506
Escherichia coli M12  CO715_12385  ATI06432.1  327 aa transcriptional regulator EbgR 8.8e-6 ●○○○○ -0.74 -0.737681795155257
Escherichia coli M12  CO715_14880  ATI06884.1  91 aa hypothetical protein 6.1e-7 ●○○○○ -0.73 -0.733717520884529
Escherichia coli M12  CO715_02840  ATI04767.1  233 aa ethanolamine utilization acetate kinase EutQ 0.00088 ●○○○○ -0.73 -0.732465644799036
Escherichia coli M12  CO715_18185  ATI07476.1  225 aa ABC transporter ATP-binding protein 0.0056 ●○○○○ -0.73 -0.731422414727791
Escherichia coli M12  CO715_18610  ATI07551.1  326 aa PTS sorbitol transporter subunit IIB 8.3e-20 ●○○○○ -0.73 -0.730796476685045
Escherichia coli M12  CO715_15505  ATI06994.1  176 aa HslU--HslV peptidase proteolytic subunit 0.00018 ●○○○○ -0.73 -0.729544600599552
Escherichia coli M12  CO715_04275  ATI05030.1  377 aa 2-iminoacetate synthase ThiH 0.00054 ●○○○○ -0.73 -0.729127308571054
Escherichia coli M12  CO715_21680  ATI08108.1  378 aa VWA domain-containing protein 0.0031 ●○○○○ -0.73 -0.728710016542556
Escherichia coli M12  CO715_10855  ATI06153.1  1018 aa FAD-binding oxidoreductase 1.3e-15 ●○○○○ -0.73 -0.72620626437157
Escherichia coli M12  CO715_18975  ATI07614.1  264 aa spermidine/putrescine ABC transporter permease 0.0011 ●○○○○ -0.72 -0.723493866186334
Escherichia coli M12  CO715_16740  ATI07219.1  133 aa class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI 0.0001 ●○○○○ -0.72 -0.721824698072344
Escherichia coli M12  CO715_23560  ATI08425.1  364 aa tRNA 2-selenouridine(34) synthase MnmH 5.8e-18 ●○○○○ -0.72 -0.721616052058095
Escherichia coli M12  CO715_23315  ATI08391.1  151 aa hypothetical protein 0.00089 ●○○○○ -0.72 -0.721198760029597
Escherichia coli M12  CO715_09950  ATI06004.1  372 aa LPS O-antigen length regulator 1.3e-11 ●○○○○ -0.72 -0.718903653872859
Escherichia coli M12  CO715_16870  ATI07240.1  165 aa nicotinamide-nucleotide amidohydrolase PncC 2.1e-13 ●○○○○ -0.72 -0.716608547716122
Escherichia coli M12  CO715_21690  ATI08110.1  362 aa MoxR family ATPase 1.0e-12 ●○○○○ -0.72 -0.71514802561638
Escherichia coli M12  CO715_00780  ATI04397.1  497 aa hypothetical protein 2.1e-79 ●○○○○ -0.71 -0.712852919459643
Escherichia coli M12  CO715_11960  ATI06359.1  567 aa hydrogenase-2 large chain 7.2e-49 ●○○○○ -0.71 -0.712435627431145
Escherichia coli M12  CO715_24335  ATI08563.1  349 aa type VI secretion system baseplate subunit TssG 1.3e-12 ●○○○○ -0.71 -0.707428123089172
Escherichia coli M12  CO715_22510  ATI08258.1  300 aa peptide ABC transporter permease 2.4e-10 ●○○○○ -0.71 -0.706593539032177
Escherichia coli M12  CO715_02160  ATI04640.1  90 aa hypothetical protein 7.1e-12 ●○○○○ -0.7 -0.703463848818444
Escherichia coli M12  CO715_19390  ATI07691.1  426 aa FAD-binding oxidoreductase 0.0053 ●○○○○ -0.7 -0.700125512590462
Escherichia coli M12  CO715_15955  ATI07073.1  729 aa fatty acid oxidation complex subunit alpha FadB <1e-323 ●○○○○ -0.7 -0.697830406433725
Escherichia coli M12  CO715_21985  ATI08165.1  405 aa colanic acid biosynthesis glycosyltransferase WcaC 1.3e-14 ●○○○○ -0.7 -0.697830406433725
Escherichia coli M12  CO715_02025  ATI04616.1  171 aa transcriptional regulator Zur 2.6e-13 ●○○○○ -0.7 -0.695743946291236
Escherichia coli M12  CO715_24595  ATI08608.1  318 aa hypothetical protein 7.3e-70 ●○○○○ -0.7 -0.695326654262738
Escherichia coli M12  CO715_19315  ATI07676.1  306 aa alpha/beta hydrolase 2.0e-12 ●○○○○ -0.69 -0.691988318034756
Escherichia coli M12  CO715_14705  ATI06852.1  198 aa 16S rRNA (guanine(966)-N(2))-methyltransferase 0.00075 ●○○○○ -0.69 -0.689901857892268
Escherichia coli M12  CO715_08605  ATI05769.1  128 aa type II toxin-antitoxin system RelE/ParE family toxin 7.3e-25 ●○○○○ -0.69 -0.689693211878019
Escherichia coli M12  CO715_12680  ATI06485.1  157 aa PTS N-acetylgalactosamine transporter subunit IIB 4.7e-5 ●○○○○ -0.69 -0.689275919849521
Retrieved entries 1,301–1,400 out of 3,550 total in 51.5 ms (Link to these results)