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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_07510  ATI05574.1  381 aa alkanesulfonate monooxygenase, FMNH(2)-dependent 4.7e-36 ●●●●● -5.71 -5.71326329694785
Escherichia coli M12  CO715_02760  ATI04753.1  232 aa esterase 1.5e-12 ●●●●● -4.54 -4.54317644904024
Escherichia coli M12  CO715_24835  ATI08647.1  321 aa bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA 4.9e-7 ●●●●● -4.48 -4.47703566252335
Escherichia coli M12  CO715_20855  ATI07958.1  138 aa flagellar biosynthesis protein FlgB 6.5e-11 ●●●●● -4.36 -4.36165441664373
Escherichia coli M12  CO715_05005  ATI05147.1  203 aa bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 6.6e-6 ●●●●○ -3.95 -3.95270822871596
Escherichia coli M12  CO715_09170  ATI05866.1  97 aa cyd operon protein YbgE 6.6e-6 ●●●○○ -2.68 -2.68330587802589
Escherichia coli M12  CO715_09615  ATI05941.1  241 aa glutamate/aspartate transport ATP-binding protein GltL 1.1e-18 ●●●○○ -2.43 -2.43084420078477
Escherichia coli M12  CO715_11890  ATI06346.1  395 aa cystathionine beta-lyase MetC 2.2e-15 ●●●○○ -2.38 -2.38097780337929
Escherichia coli M12  CO715_19880  ATI07777.1  129 aa methylated-DNA--[protein]-cysteine S-methyltransferase 3.1e-18 ●●●○○ -2.34 -2.33674484835853
Escherichia coli M12  CO715_09145  ATI05861.1  430 aa protein TolB 1.6e-11 ●●●○○ -2.34 -2.33507568024454
Escherichia coli M12  CO715_16565  ATI07187.1  1072 aa carbamoyl-phosphate synthase large subunit 3.3e-14 ●●●○○ -2.29 -2.28520928283906
Escherichia coli M12  CO715_15535  ATI06998.1  105 aa met repressor 3.6e-14 ●●●○○ -2.27 -2.27060406184164
Escherichia coli M12  CO715_11715  ATI06313.1  257 aa zinc transporter ZupT 3.2e-17 ●●●○○ -2.24 -2.24306278796079
Escherichia coli M12  CO715_12750  ATI06499.1  196 aa phosphoheptose isomerase 7.0e-10 ●●●○○ -2.24 -2.23555153144783
Escherichia coli M12  CO715_04360  ATI05046.1  429 aa phosphoribosylamine--glycine ligase 2.3e-16 ●●●○○ -2.22 -2.2234500626214
Escherichia coli M12  CO715_07050  ATI05493.1  75 aa DNA-binding protein 1.7e-13 ●●●○○ -2.22 -2.21906849632217
Escherichia coli M12  CO715_18290  ATI07494.1  165 aa SprT family protein 8.6e-17 ●●●○○ -2.22 -2.21510422205144
Escherichia coli M12  CO715_01445  ATI04511.1  602 aa fumarate reductase (quinol) flavoprotein subunit 1.1e-12 ●●●○○ -2.2 -2.19903847895428
Escherichia coli M12  CO715_05780  ATI05277.1  110 aa head decoration protein 5.7e-14 ●●●○○ -2.19 -2.19382232859806
Escherichia coli M12  CO715_07845  ATI05631.1  313 aa helix-turn-helix domain-containing protein 3.7e-8 ●●●○○ -2.19 -2.18756294817059
Escherichia coli M12  CO715_03850  ATI04950.1  256 aa pimeloyl-[acyl-carrier protein] methyl ester esterase 2.5e-13 ●●●○○ -2.19 -2.1867283641136
Escherichia coli M12  CO715_22120  ATI08188.1  309 aa branched chain amino acid aminotransferase 2.1e-15 ●●●○○ -2.14 -2.14332999314984
Escherichia coli M12  CO715_07815  ATI05625.1  127 aa antitermination protein 7.1e-11 ●●●○○ -2.14 -2.1402003029361
Escherichia coli M12  CO715_02615  ATI04724.1  688 aa polyphosphate kinase 1.6e-6 ●●●○○ -2.14 -2.1397830109076
Escherichia coli M12  CO715_08475  ATI05744.1  375 aa 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC 3.4e-12 ●●●○○ -2.14 -2.13623602866537
Escherichia coli M12  CO715_05685  ATI05262.1  99 aa DUF4222 domain-containing protein 3.8e-11 ●●●○○ -2.13 -2.13248040040889
Escherichia coli M12  CO715_21860  ATI08142.1  453 aa U32 family peptidase 2.2e-15 ●●●○○ -2.13 -2.12955935620941
Escherichia coli M12  CO715_22125  ATI08189.1  616 aa dihydroxy-acid dehydratase 4.6e-17 ●●●○○ -2.11 -2.11224173702675
Escherichia coli M12  CO715_19960  ATI07793.1  424 aa ATP-dependent Clp protease ATP-binding subunit ClpX 8.4e-5 ●●●○○ -2.11 -2.10639964862779
Escherichia coli M12  CO715_07045  ATI05492.1  99 aa hypothetical protein 0.00043 ●●●○○ -2.1 -2.1038958964568
Escherichia coli M12  CO715_09060  ATI05854.1  350 aa 3-deoxy-7-phosphoheptulonate synthase 2.6e-16 ●●●○○ -2.09 -2.08887338343088
Escherichia coli M12  CO715_13255  ATI06590.1  489 aa ribonuclease E/G 2.6e-17 ●●●○○ -2.08 -2.08428317111741
Escherichia coli M12  CO715_10170  ATI06034.1  124 aa hypothetical protein 1.0e-14 ●●●○○ -2.07 -2.07426816243346
Escherichia coli M12  CO715_05415  ATI05216.1  131 aa hypothetical protein 2.0e-13 ●●●○○ -2.07 -2.06884336606299
Escherichia coli M12  CO715_08660  ATI05779.1  220 aa fructose-6-phosphate aldolase 5.2e-12 ●●●○○ -2.07 -2.0675914899775
Escherichia coli M12  CO715_21110  ATI08006.1  396 aa anaerobic glycerol-3-phosphate dehydrogenase subunit C 1.0e-7 ●●●○○ -2.06 -2.06133210955003
Escherichia coli M12  CO715_04955  ATI05138.1  392 aa hypothetical protein 8.1e-10 ●●●○○ -2.06 -2.06070617150729
Escherichia coli M12  CO715_02600  ATI04721.1  50 aa hypothetical protein 3.0e-12 ●●●○○ -2.05 -2.05027387079484
Escherichia coli M12  CO715_18385  ATI07513.1  239 aa tRNA (guanosine(46)-N7)-methyltransferase TrmB 4.6e-14 ●●●○○ -2.05 -2.0496479327521
Escherichia coli M12  CO715_02955  ATI04787.1  298 aa N-acetylmuramic acid 6-phosphate etherase 3.7e-13 ●●●○○ -2.05 -2.04818741065235
Escherichia coli M12  CO715_15650  ATI07021.1  457 aa argininosuccinate lyase 1.3e-11 ●●●○○ -2.04 -2.0406761541394
Escherichia coli M12  CO715_13210  ATI06581.1  156 aa arginine repressor 4.9e-7 ●●●○○ -2.04 -2.03587729581167
Escherichia coli M12  CO715_19955  ATI07792.1  784 aa Lon protease 5.5e-13 ●●●○○ -2.03 -2.03337354364069
Escherichia coli M12  CO715_00470  ATI04340.1  155 aa YhcH/YjgK/YiaL family protein 2.8e-5 ●●●○○ -2.03 -2.03337354364069
Escherichia coli M12  CO715_04000  ATI04976.1  225 aa ribulose-phosphate 3-epimerase 2.7e-10 ●●●○○ -2.03 -2.03253895958369
Escherichia coli M12  CO715_04295  ATI05034.1  211 aa thiamine phosphate synthase 2.8e-15 ●●●○○ -2.03 -2.0312870834982
Escherichia coli M12  CO715_08000  ATI05658.1  355 aa 5-(carboxyamino)imidazole ribonucleotide synthase 1.7e-5 ●●●○○ -2.03 -2.02711416321322
Escherichia coli M12  CO715_07890  ATI05638.1  120 aa hypothetical protein 4.5e-13 ●●●○○ -2.02 -2.0214807208285
Escherichia coli M12  CO715_07500  ATI05572.1  191 aa NAD(P)H-dependent FMN reductase 1.5e-8 ●●●○○ -2.02 -2.02043749075726
Escherichia coli M12  CO715_17980  ATI07441.1  219 aa hemolysin III family protein 4.6e-6 ●●●○○ -2.02 -2.02043749075726
Escherichia coli M12  CO715_09940  ATI06002.1  330 aa iron-enterobactin transporter permease 1.4e-27 ●●●○○ -2.02 -2.01835103061477
Escherichia coli M12  CO715_05040  ATI05154.1  299 aa ATP phosphoribosyltransferase 1.2e-14 ●●●○○ -2.02 -2.01668186250078
Escherichia coli M12  CO715_06480  ATI05392.1  76 aa cation transport regulator ChaB 1.5e-9 ●●●○○ -2.01 -2.00791872990232
Escherichia coli M12  CO715_07035  ATI05490.1  233 aa Replication protein P 1.1e-14 ●●●○○ -2.01 -2.00750143787383
Escherichia coli M12  CO715_13300  ATI06598.1  276 aa hypothetical protein 2.4e-14 ●●○○○ -2 -1.99936424331812
Escherichia coli M12  CO715_05475  ATI05227.1  251 aa zinc ABC transporter ATP-binding protein ZnuC 9.3e-18 ●●○○○ -2 -1.99811236723263
Escherichia coli M12  CO715_03745  ATI04932.1  285 aa 1,4-dihydroxy-2-naphthoyl-CoA synthase 6.8e-11 ●●○○○ -2 -1.99644319911864
Escherichia coli M12  CO715_15150  ATI06933.1  222 aa fimbrial chaperone EcpB 4.2e-11 ●●○○○ -2 -1.99519132303314
Escherichia coli M12  CO715_12145  ATI06393.1  160 aa type II secretion system protein GspG 2.1e-149 ●●○○○ -1.99 -1.98788871253443
Escherichia coli M12  CO715_09930  ATI06000.1  416 aa MFS transporter 9.4e-13 ●●○○○ -1.99 -1.98726277449169
Escherichia coli M12  CO715_12345  ATI06426.1  254 aa siderophore-interacting protein 4.9e-13 ●●○○○ -1.99 -1.98663683644894
Escherichia coli M12  CO715_15410  ATI06978.1  320 aa ATP-dependent 6-phosphofructokinase 4.7e-8 ●●○○○ -1.98 -1.98246391616396
Escherichia coli M12  CO715_22725  ATI08292.1  259 aa 2-deoxyribose-5-phosphate aldolase 2.6e-13 ●●○○○ -1.98 -1.98037745602147
Escherichia coli M12  CO715_04835  ATI05116.1  216 aa CoA transferase subunit B 2.2e-12 ●●○○○ -1.98 -1.976621827765
Escherichia coli M12  CO715_20165  ATI07833.1  439 aa branched-chain amino acid transport system 2 carrier protein 1.2e-6 ●●○○○ -1.98 -1.9762045357365
Escherichia coli M12  CO715_17350  ATI07328.1  181 aa protein Syd 6.2e-11 ●●○○○ -1.97 -1.97057109335178
Escherichia coli M12  CO715_20410  ATI07879.1  288 aa 2-hydroxy-6-oxononadienedioate/2-hydroxy-6- oxononatrienedioate hydrolase 1.6e-7 ●●○○○ -1.97 -1.96827598719504
Escherichia coli M12  CO715_19750  ATI07754.1  434 aa inosine/guanosine kinase 6.9e-12 ●●○○○ -1.96 -1.96452035893856
Escherichia coli M12  CO715_06215  ATI05349.1  84 aa AraC family transcriptional regulator 5.4e-14 ●●○○○ -1.96 -1.96431171292431
Escherichia coli M12  CO715_06990  ATI05482.1  125 aa antitermination protein 2.0e-90 ●●○○○ -1.96 -1.96139066872483
Escherichia coli M12  CO715_17895  ATI07424.1  439 aa guanine deaminase 0.00029 ●●○○○ -1.96 -1.95638316438286
Escherichia coli M12  CO715_06140  ATI05334.1  317 aa transcriptional regulator LsrR 2.3e-14 ●●○○○ -1.95 -1.95387941221187
Escherichia coli M12  CO715_17705  ATI07391.1  79 aa type III secretion system needle complex protein 8.1e-12 ●●○○○ -1.95 -1.95033242996964
Escherichia coli M12  CO715_21805  ATI08132.1  350 aa fructose-bisphosphate aldolase 6.6e-13 ●●○○○ -1.95 -1.95012378395539
Escherichia coli M12  CO715_13120  ATI06565.1  229 aa N-acetylmannosamine-6-phosphate 2-epimerase 1.2e-27 ●●○○○ -1.95 -1.94678544772741
Escherichia coli M12  CO715_08195  ATI05695.1  230 aa DUF421 domain-containing protein 3.7e-5 ●●○○○ -1.95 -1.94532492562767
Escherichia coli M12  CO715_16980  ATI07260.1  307 aa hydrogenase 3 membrane subunit 1.0e-19 ●●○○○ -1.94 -1.94490763359917
Escherichia coli M12  CO715_18000  ATI07444.1  129 aa glycine cleavage system protein H 2.4e-8 ●●○○○ -1.94 -1.94344711149943
Escherichia coli M12  CO715_20005  ATI07802.1  663 aa cytochrome ubiquinol oxidase subunit I 5.4e-35 ●●○○○ -1.94 -1.94261252744243
Escherichia coli M12  CO715_00950  ATI04425.1  391 aa multidrug resistance protein MdtL 1.0e-11 ●●○○○ -1.94 -1.94031742128569
Escherichia coli M12  CO715_06570  ATI05408.1  84 aa hypothetical protein 2.8e-10 ●●○○○ -1.94 -1.93927419121445
Escherichia coli M12  CO715_18055  ATI07453.1  410 aa D-3-phosphoglycerate dehydrogenase 2.8e-9 ●●○○○ -1.94 -1.93802231512896
Escherichia coli M12  CO715_19245  ATI07664.1  187 aa DNA endonuclease SmrA 2.1e-12 ●●○○○ -1.93 -1.93322345680123
Escherichia coli M12  CO715_03420  ATI04869.1  361 aa chorismate synthase 0.013 ●●○○○ -1.93 -1.93113699665874
Escherichia coli M12  CO715_05855  ATI08741.1  67 aa phage tail protein 5.6e-23 ●●○○○ -1.93 -1.9292591825305
Escherichia coli M12  CO715_16570  ATI07188.1  382 aa carbamoyl-phosphate synthase small subunit 6.5e-14 ●●○○○ -1.93 -1.92905053651625
Escherichia coli M12  CO715_02995  ATI04795.1  122 aa hypothetical protein 7.1e-6 ●●○○○ -1.93 -1.92884189050201
Escherichia coli M12  CO715_23185  ATI08372.1  210 aa protein SgcE 3.8e-11 ●●○○○ -1.93 -1.92717272238801
Escherichia coli M12  CO715_05150  ATI05170.1  239 aa RNA polymerase sigma factor FliA 7.9e-15 ●●○○○ -1.93 -1.92654678434527
Escherichia coli M12  CO715_10670  ATI06119.1  215 aa ribonuclease T 5.4e-6 ●●○○○ -1.93 -1.92592084630252
Escherichia coli M12  CO715_13555  ATI06641.1  614 aa ATP-dependent DNA helicase RecQ 3.5e-21 ●●○○○ -1.92 -1.9202874039178
Escherichia coli M12  CO715_19625  ATI07734.1  531 aa bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD 1.1e-10 ●●○○○ -1.92 -1.91924417384656
Escherichia coli M12  CO715_07215  ATI05525.1  153 aa hypothetical protein 3.2e-8 ●●○○○ -1.92 -1.91882688181806
Escherichia coli M12  CO715_05895  ATI05292.1  232 aa phage minor tail protein L 2.4e-14 ●●○○○ -1.92 -1.91861823580381
Escherichia coli M12  CO715_13910  ATI06706.1  206 aa peptidylprolyl isomerase 1.3e-6 ●●○○○ -1.92 -1.91674042167557
Escherichia coli M12  CO715_12440  ATI06443.1  167 aa M48 family peptidase 0.014 ●●○○○ -1.91 -1.91194156334785
Escherichia coli M12  CO715_07995  ATI05657.1  169 aa 5-(carboxyamino)imidazole ribonucleotide mutase 2.1e-33 ●●○○○ -1.91 -1.91027239523386
Escherichia coli M12  CO715_10685  ATI06122.1  275 aa endopeptidase 7.2e-11 ●●○○○ -1.91 -1.90943781117686
Escherichia coli M12  CO715_12755  ATI06500.1  191 aa osmotically-inducible protein OsmY 8.9e-13 ●●○○○ -1.91 -1.90881187313412
Escherichia coli M12  CO715_01185  ATI04466.1  230 aa FadR family transcriptional regulator 4.7e-13 ●●○○○ -1.91 -1.90860322711987
Retrieved entries 1–100 out of 3,550 total in 82.3 ms (Link to these results)