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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_08655  ATI05778.1  249 aa molybdopterin-synthase adenylyltransferase MoeB 2.3e-8 ●●○○○ -1.75 -1.75149277839047
Escherichia coli M12  CO715_09905  ATI05995.1  248 aa 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 7.4e-10 ●●○○○ -1.75 -1.75065819433348
Escherichia coli M12  CO715_03840  ATI04948.1  191 aa Fe-S biogenesis protein NfuA 1.2e-8 ●●○○○ -1.75 -1.7473198581055
Escherichia coli M12  CO715_04365  ATI05047.1  529 aa bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 1.2e-53 ●●○○○ -1.75 -1.74565068999151
Escherichia coli M12  CO715_17470  ATI07349.1  443 aa N-acetylglutamate synthase 1.7e-10 ●●○○○ -1.75 -1.74523339796301
Escherichia coli M12  CO715_11585  ATI06290.1  206 aa hypothetical protein 9.5e-10 ●●○○○ -1.74 -1.74481610593451
Escherichia coli M12  CO715_04670  ATI05091.1  75 aa hypothetical protein 1.0e-8 ●●○○○ -1.74 -1.74439881390601
Escherichia coli M12  CO715_07260  ATI05532.1  390 aa pentaheme c-type cytochrome TorC 5.4e-12 ●●○○○ -1.74 -1.74419016789176
Escherichia coli M12  CO715_20980  ATI07983.1  269 aa aminodeoxychorismate lyase 7.0e-52 ●●○○○ -1.74 -1.74335558383477
Escherichia coli M12  CO715_05305  ATI05197.1  192 aa flagellar transcriptional regulator FlhC 0.011 ●●○○○ -1.74 -1.74252099977777
Escherichia coli M12  CO715_24635  ATI08614.1  202 aa glutathione S-transferase 0.00039 ●●○○○ -1.74 -1.74126912369228
Escherichia coli M12  CO715_08670  ATI05781.1  810 aa formate C-acetyltransferase/glycerol dehydratase family glycyl radical enzyme 1.9e-20 ●●○○○ -1.74 -1.74064318564953
Escherichia coli M12  CO715_07310  ATI08755.1  436 aa phytase AppA 5.7e-7 ●●○○○ -1.74 -1.74064318564953
Escherichia coli M12  CO715_08950  ATI05832.1  429 aa adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA 4.7e-6 ●●○○○ -1.74 -1.74022589362104
Escherichia coli M12  CO715_15120  ATI06929.1  46 aa 50S ribosomal protein L36 5.2e-10 ●●○○○ -1.74 -1.74001724760679
Escherichia coli M12  CO715_20825  ATI07952.1  215 aa DUF480 domain-containing protein 1.3e-9 ●●○○○ -1.74 -1.73918266354979
Escherichia coli M12  CO715_11540  ATI06283.1  532 aa cyclic diguanylate phosphodiesterase 6.5e-22 ●●○○○ -1.74 -1.73897401753554
Escherichia coli M12  CO715_11645  ATI06300.1  122 aa bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase 1.0e-8 ●●○○○ -1.73 -1.73271463710808
Escherichia coli M12  CO715_01390  ATI04505.1  379 aa tRNA epoxyqueuosine(34) reductase QueG 3.6e-6 ●●○○○ -1.73 -1.73146276102258
Escherichia coli M12  CO715_03695  ATI04923.1  485 aa NADH-quinone oxidoreductase subunit N 8.4e-12 ●●○○○ -1.73 -1.73125411500833
Escherichia coli M12  CO715_09965  ATI06007.1  400 aa enterochelin esterase 7.4e-35 ●●○○○ -1.73 -1.7281244247946
Escherichia coli M12  CO715_06185  ATI05343.1  156 aa hypothetical protein 2.2e-18 ●●○○○ -1.72 -1.72290827443838
Escherichia coli M12  CO715_03595  ATI04903.1  151 aa hypothetical protein 5.3e-5 ●●○○○ -1.72 -1.72290827443838
Escherichia coli M12  CO715_18195  ATI07478.1  169 aa transcriptional regulator 3.2e-14 ●●○○○ -1.72 -1.72269962842413
Escherichia coli M12  CO715_08680  ATI05783.1  421 aa DUF1479 domain-containing protein 3.5e-59 ●●○○○ -1.72 -1.72228233639563
Escherichia coli M12  CO715_10255  ATI06047.1  83 aa DNA-binding protein 7.5e-10 ●●○○○ -1.72 -1.72123910632439
Escherichia coli M12  CO715_16065  ATI07093.1  146 aa PTS sugar transporter subunit IIA 2.2e-5 ●●○○○ -1.72 -1.72082181429589
Escherichia coli M12  CO715_20845  ATI07956.1  97 aa anti-sigma-28 factor FlgM 0.023 ●●○○○ -1.72 -1.71852670813915
Escherichia coli M12  CO715_14585  ATI06830.1  194 aa DUF3261 domain-containing protein 5.1e-10 ●●○○○ -1.71 -1.71477107988267
Escherichia coli M12  CO715_05870  ATI05289.1  125 aa phage tail protein 0.00025 ●●○○○ -1.71 -1.71205868169744
Escherichia coli M12  CO715_12420  ATI06439.1  138 aa transcriptional regulator 8.5e-25 ●●○○○ -1.71 -1.71143274365469
Escherichia coli M12  CO715_12555  ATI06463.1  54 aa hypothetical protein 0.009 ●●○○○ -1.71 -1.71122409764044
Escherichia coli M12  CO715_17575  ATI07369.1  311 aa LysR family transcriptional regulator 7.0e-10 ●●○○○ -1.71 -1.7093462835122
Escherichia coli M12  CO715_07305  ATI05539.1  70 aa cold-shock protein CspH 2.5e-10 ●●○○○ -1.71 -1.70892899148371
Escherichia coli M12  CO715_17345  ATI07327.1  109 aa hypothetical protein 2.0e-6 ●●○○○ -1.71 -1.70830305344096
Escherichia coli M12  CO715_16785  ATI07228.1  111 aa L-valine transporter subunit YgaH 4.0e-9 ●●○○○ -1.71 -1.70725982336972
Escherichia coli M12  CO715_04020  ATI04980.1  120 aa PRD domain-containing protein 9.5e-5 ●●○○○ -1.71 -1.70705117735547
Escherichia coli M12  CO715_00105  ATI04276.1  143 aa nucleoside-diphosphate kinase 1.4e-8 ●●○○○ -1.71 -1.70579930126997
Escherichia coli M12  CO715_12880  ATI06523.1  447 aa argininosuccinate synthase 2.0e-6 ●●○○○ -1.7 -1.70183502699924
Escherichia coli M12  CO715_24185  ATI08538.1  157 aa hypothetical protein 1.9e-8 ●●○○○ -1.7 -1.69953992084251
Escherichia coli M12  CO715_13095  ATI06560.1  1486 aa glutamate synthase large subunit 6.3e-60 ●●○○○ -1.7 -1.69933127482826
Escherichia coli M12  CO715_04620  ATI05082.1  121 aa permease 4.0e-12 ●●○○○ -1.7 -1.69787075272852
Escherichia coli M12  CO715_06705  ATI05432.1  239 aa fatty acid metabolism transcriptional regulator FadR 3.4e-27 ●●○○○ -1.7 -1.69745346070002
Escherichia coli M12  CO715_20370  ATI07871.1  91 aa transcriptional regulator 0.0028 ●●○○○ -1.69 -1.69453241650053
Escherichia coli M12  CO715_20795  ATI07946.1  81 aa DNA-damage-inducible protein I 9.0e-12 ●●○○○ -1.69 -1.69244595635805
Escherichia coli M12  CO715_00605  ATI04367.1  187 aa DNA-3-methyladenine glycosylase I 4.3e-20 ●●○○○ -1.69 -1.69077678824406
Escherichia coli M12  CO715_11995  ATI06365.1  499 aa low-affinity inorganic phosphate transporter 2 4.4e-8 ●●○○○ -1.69 -1.68576928390208
Escherichia coli M12  CO715_02795  ATI04759.1  659 aa oxidoreductase FeS-binding subunit 6.7e-36 ●●○○○ -1.68 -1.68368282375959
Escherichia coli M12  CO715_22590  ATI08270.1  310 aa homoserine kinase 1.7e-30 ●●○○○ -1.68 -1.68347417774535
Escherichia coli M12  CO715_03510  ATI04886.1  505 aa amidophosphoribosyltransferase 2.9e-8 ●●○○○ -1.68 -1.68305688571685
Escherichia coli M12  CO715_21010  ATI07989.1  729 aa TonB-dependent siderophore receptor 7.1e-18 ●●○○○ -1.68 -1.68263959368835
Escherichia coli M12  CO715_13955  ATI06712.1  134 aa Rcs stress response system protein RcsF 1.3e-10 ●●○○○ -1.68 -1.6824309476741
Escherichia coli M12  CO715_19375  ATI07688.1  222 aa phage shock protein A 0.026 ●●○○○ -1.68 -1.68159636361711
Escherichia coli M12  CO715_02300  ATI04665.1  427 aa murein hydrolase activator EnvC 9.4e-49 ●●○○○ -1.68 -1.68138771760286
Escherichia coli M12  CO715_04070  ATI04990.1  108 aa nitrite reductase small subunit 0.00064 ●●○○○ -1.68 -1.67971854948887
Escherichia coli M12  CO715_10640  ATI08788.1  173 aa superoxide dismutase [Cu-Zn] SodC2 0.001 ●●○○○ -1.68 -1.67909261144612
Escherichia coli M12  CO715_04290  ATI05033.1  251 aa thiazole biosynthesis adenylyltransferase ThiF 1.3e-62 ●●○○○ -1.68 -1.67825802738912
Escherichia coli M12  CO715_02745  ATI04750.1  237 aa phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.026 ●●○○○ -1.68 -1.67742344333213
Escherichia coli M12  CO715_22820  ATI08309.1  157 aa hypothetical protein 3.0e-7 ●●○○○ -1.67 -1.67491969116114
Escherichia coli M12  CO715_11905  ATI06349.1  141 aa biopolymer transporter ExbD 0.0062 ●●○○○ -1.67 -1.67471104514689
Escherichia coli M12  CO715_03360  ATI04858.1  436 aa acetyl-CoA C-acyltransferase FadI 9.6e-56 ●●○○○ -1.67 -1.67408510710415
Escherichia coli M12  CO715_07540  ATI05580.1  514 aa nitrate reductase subunit beta 1.6e-7 ●●○○○ -1.67 -1.66928624877642
Escherichia coli M12  CO715_04925  ATI05134.1  87 aa protein NapD 2.4e-8 ●●○○○ -1.67 -1.66740843464818
Escherichia coli M12  CO715_03690  ATI04922.1  509 aa NADH-quinone oxidoreductase subunit M 4.5e-5 ●●○○○ -1.67 -1.66699114261968
Escherichia coli M12  CO715_06160  ATI05338.1  440 aa type II toxin-antitoxin system HipA family toxin 0.00057 ●●○○○ -1.67 -1.66699114261968
Escherichia coli M12  CO715_03930  ATI04963.1  133 aa heat-shock protein 15 0.0001 ●●○○○ -1.67 -1.66573926653419
Escherichia coli M12  CO715_15785  ATI07041.1  298 aa tyrosine recombinase XerC 3.8e-5 ●●○○○ -1.66 -1.66469603646295
Escherichia coli M12  CO715_13335  ATI06605.1  321 aa tRNA dihydrouridine synthase DusB 5.5e-13 ●●○○○ -1.66 -1.6636528063917
Escherichia coli M12  CO715_15260  ATI06952.1  290 aa hypothetical protein 2.0e-11 ●●○○○ -1.66 -1.66344416037745
Escherichia coli M12  CO715_03300  ATI04847.1  63 aa hypothetical protein 0.0041 ●●○○○ -1.66 -1.66135770023497
Escherichia coli M12  CO715_24480  ATI08588.1  579 aa flagellar type III secretion system protein FlhA 3.8e-5 ●●○○○ -1.66 -1.66031447016372
Escherichia coli M12  CO715_08925  ATI05827.1  673 aa excinuclease ABC subunit B 4.5e-11 ●●○○○ -1.66 -1.65906259407823
Escherichia coli M12  CO715_15055  ATI06916.1  197 aa hypothetical protein 9.8e-9 ●●○○○ -1.66 -1.65885394806398
Escherichia coli M12  CO715_03810  ATI04943.1  180 aa hypothetical protein 2.0e-23 ●●○○○ -1.66 -1.65822801002123
Escherichia coli M12  CO715_03835  ATI04947.1  438 aa gluconate transporter 1.2e-26 ●●○○○ -1.66 -1.65614154987874
Escherichia coli M12  CO715_18235  ATI07485.1  252 aa metalloprotease 1.1e-16 ●●○○○ -1.66 -1.65572425785025
Escherichia coli M12  CO715_24730  ATI08631.1  89 aa hypothetical protein 0.0049 ●●○○○ -1.65 -1.65009081546553
Escherichia coli M12  CO715_17955  ATI07436.1  298 aa site-specific tyrosine recombinase XerD 0.0021 ●●○○○ -1.65 -1.64988216945128
Escherichia coli M12  CO715_12115  ATI06388.1  269 aa prepilin peptidase 6.5e-11 ●●○○○ -1.65 -1.64904758539428
Escherichia coli M12  CO715_19640  ATI07736.1  268 aa tryptophan synthase subunit alpha 0.028 ●●○○○ -1.65 -1.64863029336579
Escherichia coli M12  CO715_22260  ATI08214.1  432 aa MFS transporter 1.3e-12 ●●○○○ -1.65 -1.64550060315205
Escherichia coli M12  CO715_08260  ATI05707.1  447 aa replication-associated recombination protein A 0.0034 ●●○○○ -1.65 -1.64550060315205
Escherichia coli M12  CO715_24555  ATI08602.1  367 aa glutamate 5-kinase 3.2e-25 ●●○○○ -1.64 -1.64320549699532
Escherichia coli M12  CO715_05025  ATI05151.1  355 aa bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 2.6e-10 ●●○○○ -1.64 -1.64278820496682
Escherichia coli M12  CO715_15575  ATI07006.1  205 aa DUF1287 domain-containing protein 1.9e-11 ●●○○○ -1.64 -1.64257955895257
Escherichia coli M12  CO715_08070  ATI05671.1  362 aa phosphoporin PhoE 2.2e-13 ●●○○○ -1.64 -1.63965851475308
Escherichia coli M12  CO715_07780  ATI05620.1  318 aa iron-dicitrate transporter subunit FecD 2.8e-8 ●●○○○ -1.64 -1.63944986873884
Escherichia coli M12  CO715_12690  ATI06487.1  292 aa PTS N-acetylgalactosamine transporter subunit IID 5.2e-8 ●●○○○ -1.64 -1.63819799265334
Escherichia coli M12  CO715_10610  ATI06109.1  369 aa anhydro-N-acetylmuramic acid kinase 4.0e-5 ●●○○○ -1.64 -1.63819799265334
Escherichia coli M12  CO715_11495  ATI06274.1  193 aa hypothetical protein 0.00074 ●●○○○ -1.64 -1.63736340859635
Escherichia coli M12  CO715_17960  ATI07437.1  173 aa flavodoxin-2 0.0089 ●●○○○ -1.64 -1.6367374705536
Escherichia coli M12  CO715_05560  ATI05242.1  220 aa DNA polymerase III subunit epsilon 9.2e-10 ●●○○○ -1.64 -1.63527694845386
Escherichia coli M12  CO715_09035  ATI05849.1  338 aa UDP-glucose 4-epimerase GalE 0.029 ●●○○○ -1.63 -1.63465101041111
Escherichia coli M12  CO715_20715  ATI08879.1  473 aa phospholipase D family protein 2.8e-10 ●●○○○ -1.63 -1.63319048831137
Escherichia coli M12  CO715_24845  ATI08649.1  64 aa hypothetical protein 1.4e-6 ●●○○○ -1.63 -1.63235590425437
Escherichia coli M12  CO715_06915  ATI05469.1  285 aa metal ABC transporter permease 2.3e-5 ●●○○○ -1.63 -1.63235590425437
Escherichia coli M12  CO715_18345  ATI07505.1  378 aa YggW family oxidoreductase 1.5e-9 ●●○○○ -1.63 -1.63047809012613
Escherichia coli M12  CO715_16100  ATI07099.1  115 aa hypothetical protein 2.2e-5 ●●○○○ -1.63 -1.63006079809764
Escherichia coli M12  CO715_09900  ATI05994.1  137 aa proofreading thioesterase EntH 0.029 ●●○○○ -1.63 -1.62943486005489
Escherichia coli M12  CO715_16145  ATI07108.1  887 aa pyruvate dehydrogenase E1 component 2.9e-9 ●●○○○ -1.63 -1.62630516984116
Retrieved entries 201–300 out of 3,550 total in 49.5 ms (Link to these results)