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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_03790  ATI04939.1  322 aa undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase 1.3e-30 ●○○○○ -0.69 -0.688441335792526
Escherichia coli M12  CO715_13375  ATI06612.1  73 aa hypothetical protein 6.5e-7 ●○○○○ -0.69 -0.687189459707033
Escherichia coli M12  CO715_20345  ATI07867.1  320 aa taurine ABC transporter substrate-binding protein 5.7e-16 ●○○○○ -0.69 -0.686980813692784
Escherichia coli M12  CO715_11160  ATI06211.1  161 aa ATP-independent periplasmic protein-refolding chaperone 1.4e-17 ●○○○○ -0.69 -0.686772167678535
Escherichia coli M12  CO715_01290  ATI04486.1  387 aa hypothetical protein 6.5e-8 ●○○○○ -0.69 -0.685728937607291
Escherichia coli M12  CO715_07475  ATI05568.1  702 aa bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL 5.6e-41 ●○○○○ -0.69 -0.685311645578793
Escherichia coli M12  CO715_07345  ATI05545.1  597 aa hydrogenase 2 large subunit 9.9e-45 ●○○○○ -0.68 -0.684685707536046
Escherichia coli M12  CO715_13245  ATI06588.1  481 aa metalloprotease TldD 0.0001 ●○○○○ -0.68 -0.683016539422055
Escherichia coli M12  CO715_10035  ATI06016.1  192 aa phage tail protein 0.027 ●○○○○ -0.68 -0.682599247393558
Escherichia coli M12  CO715_16990  ATI07262.1  203 aa formate hydrogenlyase subunit 2 9.7e-9 ●○○○○ -0.68 -0.681138725293816
Escherichia coli M12  CO715_12465  ATI06447.1  414 aa serine/threonine transporter SstT 1.7e-81 ●○○○○ -0.68 -0.679052265151327
Escherichia coli M12  CO715_19830  ATI07769.1  215 aa DNA-binding transcriptional repressor AcrR 3.8e-27 ●○○○○ -0.68 -0.67842632710858
Escherichia coli M12  CO715_12760  ATI06501.1  346 aa permease 2.7e-8 ●○○○○ -0.68 -0.676548512980341
Escherichia coli M12  CO715_09490  ATI05924.1  648 aa PTS N-acetyl glucosamine transporter subunit IIABC 2.0e-8 ●○○○○ -0.68 -0.675713928923345
Escherichia coli M12  CO715_03815  ATI04944.1  402 aa competence/damage-inducible protein A 0.014 ●○○○○ -0.68 -0.675296636894848
Escherichia coli M12  CO715_03630  ATI04910.1  312 aa transcriptional regulator 5.4e-28 ●○○○○ -0.68 -0.675087990880599
Escherichia coli M12  CO715_01715  ATI08707.1  111 aa protein PhnA 1.0e-16 ●○○○○ -0.68 -0.675087990880599
Escherichia coli M12  CO715_24670  ATI08621.1  120 aa hypothetical protein 0.0003 ●○○○○ -0.67 -0.673627468780857
Escherichia coli M12  CO715_16680  ATI07207.1  149 aa peptidoglycan-binding protein LysM 2.2e-6 ●○○○○ -0.67 -0.671541008638368
Escherichia coli M12  CO715_21555  ATI08087.1  294 aa cytidine deaminase 1.3e-37 ●○○○○ -0.67 -0.669871840524377
Escherichia coli M12  CO715_11180  ATI06215.1  344 aa arginine N-succinyltransferase 3.6e-16 ●○○○○ -0.67 -0.669454548495879
Escherichia coli M12  CO715_08760  ATI05796.1  248 aa amino acid ABC transporter substrate-binding protein 6.8e-23 ●○○○○ -0.67 -0.669245902481631
Escherichia coli M12  CO715_08085  ATI05674.1  215 aa MBL fold metallo-hydrolase 1.1e-12 ●○○○○ -0.67 -0.667159442339142
Escherichia coli M12  CO715_06080  ATI08745.1  315 aa GGDEF domain-containing protein 1.1e-20 ●○○○○ -0.67 -0.666950796324893
Escherichia coli M12  CO715_10105  ATI06026.1  70 aa cold-shock protein CspI 6.7e-8 ●○○○○ -0.67 -0.666950796324893
Escherichia coli M12  CO715_19815  ATI07766.1  54 aa DUF2496 domain-containing protein 2.8e-11 ●○○○○ -0.67 -0.665907566253649
Escherichia coli M12  CO715_08360  ATI05724.1  231 aa aquaporin 7.8e-9 ●○○○○ -0.67 -0.6656989202394
Escherichia coli M12  CO715_18130  ATI07466.1  347 aa ABC transporter substrate-binding protein 5.3e-10 ●○○○○ -0.66 -0.664238398139658
Escherichia coli M12  CO715_19385  ATI07690.1  421 aa 4-aminobutyrate transaminase 1.0e-8 ●○○○○ -0.66 -0.657353079669445
Escherichia coli M12  CO715_02240  ATI04656.1  533 aa malate synthase A 5.7e-32 ●○○○○ -0.66 -0.656727141626699
Escherichia coli M12  CO715_21505  ATI08077.1  385 aa DUF418 family protein 0.00048 ●○○○○ -0.66 -0.656309849598201
Escherichia coli M12  CO715_04080  ATI04992.1  393 aa MFS transporter 2.4e-6 ●○○○○ -0.66 -0.655266619526957
Escherichia coli M12  CO715_14695  ATI06850.1  119 aa hypothetical protein 0.024 ●○○○○ -0.65 -0.653388805398717
Escherichia coli M12  CO715_21625  ATI08097.1  305 aa ABC transporter substrate-binding protein 2.6e-5 ●○○○○ -0.65 -0.650885053227731
Escherichia coli M12  CO715_09510  ATI05928.1  250 aa ribonucleotide monophosphatase NagD 2.1e-5 ●○○○○ -0.65 -0.650676407213482
Escherichia coli M12  CO715_16965  ATI07257.1  255 aa formate hydrogenlyase 4.1e-10 ●○○○○ -0.65 -0.648381301056744
Escherichia coli M12  CO715_20720  ATI07932.1  385 aa glucan biosynthesis protein C 4.0e-83 ●○○○○ -0.65 -0.645668902871509
Escherichia coli M12  CO715_12175  ATI06399.1  178 aa general secretion pathway protein 1.4e-11 ●○○○○ -0.64 -0.644625672800265
Escherichia coli M12  CO715_17415  ATI07341.1  366 aa 23S rRNA (cytidine(2498)-2'-O)-methyltransferase RlmM 1.4e-25 ●○○○○ -0.64 -0.643999734757518
Escherichia coli M12  CO715_21000  ATI07987.1  265 aa metal-dependent hydrolase 0.00077 ●○○○○ -0.64 -0.643373796714772
Escherichia coli M12  CO715_00115  ATI04278.1  337 aa cytoskeleton protein RodZ 0.023 ●○○○○ -0.64 -0.642121920629279
Escherichia coli M12  CO715_16310  ATI07139.1  152 aa division/cell wall cluster transcriptional repressor MraZ 1.1e-22 ●○○○○ -0.64 -0.63815764635855
Escherichia coli M12  CO715_06040  ATI05316.1  221 aa stress protection protein MarC 0.002 ●○○○○ -0.64 -0.636697124258808
Escherichia coli M12  CO715_01180  ATI04465.1  475 aa MFS transporter 1.6e-7 ●○○○○ -0.64 -0.635653894187564
Escherichia coli M12  CO715_04845  ATI05118.1  461 aa two-component system response regulator 2.6e-7 ●○○○○ -0.64 -0.635236602159066
Escherichia coli M12  CO715_06960  ATI05476.1  153 aa lysis protein 2.7e-6 ●○○○○ -0.63 -0.633776080059324
Escherichia coli M12  CO715_13940  ATI06709.1  343 aa methionine import ATP-binding protein MetN 3.0e-15 ●○○○○ -0.63 -0.629185867745849
Escherichia coli M12  CO715_08045  ATI05667.1  433 aa uracil/xanthine transporter 8.8e-6 ●○○○○ -0.63 -0.629185867745849
Escherichia coli M12  CO715_23190  ATI08373.1  260 aa transcriptional regulator 1.2e-7 ●○○○○ -0.63 -0.628559929703103
Escherichia coli M12  CO715_00890  ATI04414.1  357 aa DNA replication and repair protein RecF 2.5e-20 ●○○○○ -0.63 -0.627099407603361
Escherichia coli M12  CO715_17510  ATI07357.1  156 aa prepilin-type cleavage/methylation domain-containing protein 0.00039 ●○○○○ -0.62 -0.624387009418126
Escherichia coli M12  CO715_20595  ATI07912.1  447 aa hypothetical protein 1.3e-5 ●○○○○ -0.62 -0.620840027175895
Escherichia coli M12  CO715_19905  ATI07782.1  593 aa multidrug resistance-like ATP-binding protein MdlB 8.7e-36 ●○○○○ -0.62 -0.620422735147397
Escherichia coli M12  CO715_16025  ATI07085.1  264 aa 3-methyl-2-oxobutanoate hydroxymethyltransferase 2.0e-6 ●○○○○ -0.62 -0.619379505076153
Escherichia coli M12  CO715_01750  ATI04565.1  194 aa phosphonate C-P lyase system protein PhnH 1.9e-7 ●○○○○ -0.62 -0.616458460876669
Escherichia coli M12  CO715_20400  ATI07877.1  316 aa acetaldehyde dehydrogenase 0.00069 ●○○○○ -0.61 -0.610407726463452
Escherichia coli M12  CO715_14560  ATI06825.1  195 aa 4'-phosphopantetheinyl transferase AcpT 9.6e-7 ●○○○○ -0.61 -0.608112620306714
Escherichia coli M12  CO715_06770  ATI05444.1  231 aa septum site-determining protein MinC 1.5e-36 ●○○○○ -0.61 -0.607903974292465
Escherichia coli M12  CO715_11065  ATI06193.1  178 aa hypothetical protein 1.2e-49 ●○○○○ -0.61 -0.60706939023547
Escherichia coli M12  CO715_00320  ATI04316.1  112 aa nitrogen regulatory protein P-II 1 2.2e-13 ●○○○○ -0.61 -0.606234806178474
Escherichia coli M12  CO715_12245  ATI06410.1  295 aa dTDP-4-dehydrorhamnose reductase 5.6e-5 ●○○○○ -0.6 -0.603731054007488
Escherichia coli M12  CO715_04665  ATI05090.1  271 aa mannosyl-3-phosphoglycerate phosphatase-related protein 3.2e-9 ●○○○○ -0.6 -0.603522407993239
Escherichia coli M12  CO715_10240  ATI06044.1  62 aa cell division inhibition protein DicB 1.2e-10 ●○○○○ -0.6 -0.600392717779506
Escherichia coli M12  CO715_08810  ATI05806.1  361 aa malate/lactate/ureidoglycolate dehydrogenase 6.3e-5 ●○○○○ -0.6 -0.600392717779506
Escherichia coli M12  CO715_21095  ATI08003.1  267 aa 2-keto-3-deoxy-L-rhamnonate aldolase 0.029 ●○○○○ -0.6 -0.597471673580022
Escherichia coli M12  CO715_06195  ATI05345.1  190 aa flavodoxin family protein 3.7e-8 ●○○○○ -0.6 -0.595385213437534
Escherichia coli M12  CO715_07660  ATI05603.1  193 aa D-alanyl-D-alanine dipeptidase 0.028 ●○○○○ -0.6 -0.595385213437534
Escherichia coli M12  CO715_24135  ATI08528.1  122 aa hypothetical protein 5.1e-6 ●○○○○ -0.59 -0.594550629380538
Escherichia coli M12  CO715_04735  ATI05103.1  457 aa flagellum-specific ATP synthase FliL 0.0014 ●○○○○ -0.59 -0.593924691337792
Escherichia coli M12  CO715_18845  ATI07592.1  189 aa flavin reductase family protein 2.0e-25 ●○○○○ -0.59 -0.593090107280796
Escherichia coli M12  CO715_06820  ATI05452.1  327 aa porin 1.1e-53 ●○○○○ -0.59 -0.591838231195303
Escherichia coli M12  CO715_11350  ATI06247.1  331 aa aldehyde dehydrogenase 7.0e-27 ●○○○○ -0.59 -0.586204788810584
Escherichia coli M12  CO715_03250  ATI08714.1  331 aa transcriptional regulator 3.7e-10 ●○○○○ -0.59 -0.585578850767837
Escherichia coli M12  CO715_01935  ATI04599.1  154 aa redox-sensitive transcriptional activator SoxR 6.7e-7 ●○○○○ -0.58 -0.581823222511358
Escherichia coli M12  CO715_09920  ATI05998.1  391 aa isochorismate synthase EntC 0.0012 ●○○○○ -0.58 -0.581197284468611
Escherichia coli M12  CO715_08860  ATI05814.1  368 aa inner membrane transport permease YbhR 4.7e-6 ●○○○○ -0.58 -0.57765030222638
Escherichia coli M12  CO715_13125  ATI06566.1  496 aa MFS transporter 5.6e-8 ●○○○○ -0.57 -0.574311965998399
Escherichia coli M12  CO715_02900  ATI04777.1  219 aa ethanolamine utilization microcompartment protein EutL 0.018 ●○○○○ -0.57 -0.573686027955652
Escherichia coli M12  CO715_18775  ATI07579.1  160 aa hypothetical protein 0.034 ●○○○○ -0.57 -0.570556337741919
Escherichia coli M12  CO715_06130  ATI05332.1  342 aa autoinducer 2 ABC transporter permease LsrC 1.1e-8 ●○○○○ -0.57 -0.569095815642177
Escherichia coli M12  CO715_19175  ATI07651.1  107 aa DUF1318 domain-containing protein 5.4e-12 ●○○○○ -0.57 -0.568052585570933
Escherichia coli M12  CO715_24445  ATI08581.1  814 aa acyl-CoA dehydrogenase 9.9e-19 ●○○○○ -0.57 -0.567843939556684
Escherichia coli M12  CO715_15895  ATI07061.1  475 aa DNA recombination protein RmuC 0.0011 ●○○○○ -0.57 -0.567635293542435
Escherichia coli M12  CO715_11325  ATI06242.1  347 aa NAD(P)-dependent alcohol dehydrogenase 1.2e-51 ●○○○○ -0.57 -0.565966125428444
Escherichia coli M12  CO715_16585  ATI07190.1  304 aa non-specific ribonucleoside hydrolase RihC 1.6e-38 ●○○○○ -0.57 -0.565548833399947
Escherichia coli M12  CO715_17670  ATI07386.1  167 aa lytic transglycosylase 0.0069 ●○○○○ -0.56 -0.5649228953572
Escherichia coli M12  CO715_21360  ATI08049.1  518 aa phage resistance protein 0.025 ●○○○○ -0.56 -0.563462373257458
Escherichia coli M12  CO715_06005  ATI05309.1  296 aa sensor domain-containing diguanylate cyclase 4.7e-15 ●○○○○ -0.56 -0.561793205143467
Escherichia coli M12  CO715_01350  ATI04497.1  419 aa protease modulator HflK 4.2e-9 ●○○○○ -0.56 -0.558454868915485
Escherichia coli M12  CO715_09320  ATI05893.1  816 aa fimbrial biogenesis outer membrane usher protein 8.2e-119 ●○○○○ -0.56 -0.55762028485849
Escherichia coli M12  CO715_00490  ATI04344.1  417 aa valine--pyruvate transaminase 6.3e-6 ●○○○○ -0.56 -0.557411638844241
Escherichia coli M12  CO715_14540  ATI06821.1  254 aa nickel import ATP-binding protein NikD 9.7e-27 ●○○○○ -0.56 -0.556994346815743
Escherichia coli M12  CO715_01340  ATI04495.1  65 aa DUF2065 domain-containing protein 0.0086 ●○○○○ -0.56 -0.556577054787246
Escherichia coli M12  CO715_10535  ATI06096.1  146 aa DUF2569 domain-containing protein 7.1e-13 ●○○○○ -0.56 -0.556159762758748
Escherichia coli M12  CO715_05735  ATI05272.1  253 aa abortive phage resistance protein 5.2e-16 ●○○○○ -0.56 -0.555325178701752
Escherichia coli M12  CO715_20425  ATI07881.1  315 aa transcriptional regulator 6.3e-9 ●○○○○ -0.56 -0.555116532687503
Escherichia coli M12  CO715_14685  ATI06848.1  732 aa zinc/cadmium/mercury/lead-transporting ATPase 1.4e-61 ●○○○○ -0.55 -0.554699240659006
Escherichia coli M12  CO715_09330  ATI05895.1  353 aa hypothetical protein 7.7e-12 ●○○○○ -0.55 -0.554699240659006
Escherichia coli M12  CO715_12020  ATI06370.1  274 aa hypothetical protein 2.7e-36 ●○○○○ -0.55 -0.551360904431024
Escherichia coli M12  CO715_03460  ATI04876.1  392 aa arabinose transporter 5.8e-6 ●○○○○ -0.55 -0.550109028345531
Retrieved entries 1,401–1,500 out of 3,550 total in 52.3 ms (Link to these results)