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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_06755  ATI05441.1  133 aa inhibitor of g-type lysozyme 6.2e-43 ●●○○○ -1.03 -1.02561329481869
Escherichia coli M12  CO715_03180  ATI04826.1  306 aa lipid A biosynthesis palmitoleoyl acyltransferase 5.4e-10 ●●○○○ -1.03 -1.02561329481869
Escherichia coli M12  CO715_15640  ATI07019.1  334 aa N-acetyl-gamma-glutamyl-phosphate reductase 3.2e-15 ●●○○○ -1.02 -1.02394412670469
Escherichia coli M12  CO715_21135  ATI08011.1  356 aa hypothetical protein 7.3e-86 ●●○○○ -1.02 -1.02373548069045
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1963  WP_000754800.1  E8XA77  185 aa DJ-1 family protein 3.7e-11 ●●○○○ -1.02 -1.02344314952965
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1118  NP_230763.1  Q9KSY8  142 aa transcriptional regulator 1.8e-6 ●●○○○ -1.02 -1.02188075928343
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3066  WP_000253545.1  E8XL54  pcm  208 aa protein-L-isoaspartate(D-aspartate) O-methyltransferase 0.04 ●●○○○ -1.02 -1.02185818957192
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1372  NP_231016.1  Q9KS87  392 aa GGDEF family protein 4.3e-10 ●●○○○ -1.02 -1.02170609655089
Escherichia coli M12  CO715_05120  ATI05165.1  69 aa antitoxin of toxin-antitoxin stability system 2.1e-16 ●●○○○ -1.02 -1.02164902054796
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0213  NP_229870.1  Q9KVD3  lpxL  318 aa lipid A biosynthesis lauroyl acyltransferase 7.3e-6 ●●○○○ -1.02 -1.02146644792968
Escherichia coli M12  CO715_05590  ATI05248.1  218 aa protein-serine/threonine phosphatase 0.001 ●●○○○ -1.02 -1.02081443649096
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3532  WP_000210306.1  E8XD75  maf  197 aa septum formation inhibitor Maf 0.044 ●●○○○ -1.02 -1.02038665002682
Escherichia coli M12  CO715_00355  ATI04322.1  332 aa sugar ABC transporter permease 9.0e-9 ●●○○○ -1.02 -1.01935391439122
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2070  AIK80675.1  355 aa phosphoribosylaminoimidazole carboxylase, ATPasesubunit 0.00055 ●●○○○ -1.02 -1.01848201851722
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0281  NP_232677.1  Q9KMP2  385 aa integrase 0.0046 ●●○○○ -1.02 -1.01765001191666
Escherichia coli M12  CO715_06035  ATI05315.1  144 aa multiple antibiotic resistance transcriptional regulator MarR 2.8e-6 ●●○○○ -1.02 -1.01747610026298
Escherichia coli M12  CO715_22295  ATI08221.1  345 aa tRNA/rRNA methyltransferase 1.6e-9 ●●○○○ -1.02 -1.01726745424873
Escherichia coli M12  CO715_16865  ATI07239.1  353 aa DNA recombination/repair protein RecA 8.0e-5 ●●○○○ -1.02 -1.01726745424873
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3320  AIK81877.1  139 aa D-ribose utilization <1e-323 ●●○○○ -1.02 -1.01596717820902
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1614  AIK80234.1  183 aa putative bacterial nucleoid DNA-binding protein 0.021 ●●○○○ -1.02 -1.01589664069229
Escherichia coli M12  CO715_10995  ATI06179.1  326 aa vitamin B12 import system permease BtuC 5.0e-10 ●●○○○ -1.02 -1.01580693214899
Escherichia coli M12  CO715_09685  ATI05954.1  203 aa adenosylcobalamin/alpha-ribazole phosphatase 2.2e-15 ●●○○○ -1.01 -1.01497234809199
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4300  AIK82845.1  417 aa N-acetylmuramyl-L-alanine amidase 1.8e-9 ●●○○○ -1.01 -1.01411107411875
Escherichia coli M12  CO715_09045  ATI05851.1  382 aa galactokinase 5.2e-5 ●●○○○ -1.01 -1.01392911802075
Escherichia coli M12  CO715_21470  ATI08070.1  489 aa lysine transporter 3.1e-12 ●●○○○ -1.01 -1.01351182599225
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4617  WP_000083110.1  E8XBH3  478 aa myo-inositol import MFS transporter IolT2 6.0e-5 ●●○○○ -1.01 -1.01341720081617
Porphyromonas gingivalis ATCC 33277  PGN_0416  WP_005873496.1  B2RHU0  337 aa hypothetical protein <1e-323 ●●○○○ -1.01 -1.01326861188117
Escherichia coli M12  CO715_21960  ATI08160.1  379 aa lipoprotein 9.7e-85 ●●○○○ -1.01 -1.01246859592101
Porphyromonas gingivalis ATCC 33277  PGN_0959  WP_021663951.1  B2RJD3  104 aa XRE family transcriptional regulator <1e-323 ●●○○○ -1.01 -1.01185560290921
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1684  NP_231320.1  Q9KRF8  262 aa peptide ABC transporter ATP-binding protein 1.9e-6 ●●○○○ -1.01 -1.01182107289151
Escherichia coli M12  CO715_18945  ATI07610.1  77 aa hypothetical protein 1.3e-5 ●●○○○ -1.01 -1.01163401186401
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3140  AIK81713.1  263 aa magnesium-dependent DNase 1.4e-5 ●●○○○ -1.01 -1.01040835373583
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0212  WP_000845425.1  E8XI01  yadQ  473 aa H(+)/Cl(-) exchange transporter ClcA 4.5e-6 ●●○○○ -1.01 -1.01029083322991
Escherichia coli M12  CO715_05980  ATI05306.1  248 aa NAD(P)-dependent oxidoreductase 1.2e-22 ●●○○○ -1.01 -1.01017348976427
Escherichia coli M12  CO715_16820  ATI07235.1  188 aa fructose-1-phosphate/6-phosphogluconate phosphatase 0.0033 ●●○○○ -1.01 -1.01017348976427
Escherichia coli M12  CO715_16975  ATI07259.1  569 aa hydrogenase large subunit 4.9e-44 ●●○○○ -1.01 -1.00975619773577
Escherichia coli M12  CO715_18995  ATI07618.1  468 aa PLP-dependent aminotransferase family protein 4.8e-10 ●●○○○ -1.01 -1.00954755172152
Escherichia coli M12  CO715_19970  ATI07795.1  432 aa trigger factor 7.1e-6 ●●○○○ -1.01 -1.00954755172152
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4486  AIK83029.1  166 aa recX family protein 9.3e-6 ●●○○○ -1.01 -1.00915543094441
Escherichia coli M12  CO715_19650  ATI07738.1  166 aa YciE/YciF family protein 1.6e-70 ●●○○○ -1.01 -1.00850432165028
Escherichia coli M12  CO715_05425  ATI05218.1  188 aa hydrolase 2.0e-7 ●●○○○ -1.01 -1.00850432165028
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2997  AIK81582.1  185 aa fimbrial family protein 8.9e-16 ●●○○○ -1.01 -1.0084704976927
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1595  WP_000200329.1  E8XJ30  nhoA  281 aa N-hydroxyarylamine O-acetyltransferase 1.5e-5 ●●○○○ -1.01 -1.00792771287747
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4707  AIK83241.1  117 aa transcriptional regulator, Spx/MgsR family protein <1e-323 ●●○○○ -1.01 -1.00721993698053
Escherichia coli M12  CO715_17040  ATI07270.1  114 aa nitrous oxide-stimulated promoter family protein 2.1e-17 ●●○○○ -1.01 -1.00683515353629
Escherichia coli M12  CO715_17800  ATI07408.1  250 aa hypothetical protein 1.2e-43 ●●○○○ -1.01 -1.00620921549354
Porphyromonas gingivalis ATCC 33277  PGN_0779  WP_004585294.1  B2RIV3  upp  216 aa uracil phosphoribosyltransferase <1e-323 ●●○○○ -1.01 -1.0061626993063
Acinetobacter baumannii ATCC 17978  A1S_0493  ABO10946.2  727 aa carboxy-terminal protease 9.6e-10 ●●○○○ -1.01 -1.00569039371145
Escherichia coli M12  CO715_20630  ATI07918.1  228 aa DUF2726 domain-containing protein 1.1e-29 ●●○○○ -1.01 -1.00558327745079
Escherichia coli M12  CO715_18180  ATI08854.1  225 aa cobalt ABC transporter ATP-binding protein 4.5e-7 ●●○○○ -1.01 -1.0051659854223
Escherichia coli M12  CO715_04970  ATI05141.1  376 aa UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) 4.8e-70 ●●○○○ -1 -1.00495733940805
Escherichia coli M12  CO715_19275  ATI07668.1  508 aa p-aminobenzoyl-glutamate transporter 1.1e-30 ●●○○○ -1 -1.00495733940805
Escherichia coli M12  CO715_06830  ATI05454.1  72 aa hypothetical protein 5.5e-19 ●●○○○ -1 -1.00495733940805
Escherichia coli M12  CO715_09580  ATI05935.1  359 aa PhoH family protein 6.3e-28 ●●○○○ -1 -1.00454004737955
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3090  AIK81671.1  145 aa heavy-metal resistance family protein 6.8e-14 ●●○○○ -1 -1.00421132778764
Escherichia coli CFT073  c1889  AAN80349.1  A0A0H2V7C5  200 aa Hypothetical protein 0.0087 ●●○○○ -1 -1.00414811639419
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4291  WP_000108103.1  E8XL63  katG  726 aa catalase/peroxidase HPI 0.047 ●●○○○ -1 -1.00401832930384
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0203  WP_001526021.1  E8XHZ2  fhuB  68 aa hypothetical protein 5.3e-9 ●●○○○ -1 -1.00378660795881
Escherichia coli M12  CO715_03620  ATI04908.1  405 aa glutamate--pyruvate aminotransferase AlaA 1.3e-56 ●●○○○ -1 -1.00370546332256
Porphyromonas gingivalis ATCC 33277  PGN_0088  WP_009347177.1  B2RGW2  69 aa XRE family transcriptional regulator <1e-323 ●●○○○ -1 -1.00303889670621
Escherichia coli M12  CO715_19130  ATI07643.1  1300 aa ATP-dependent RNA helicase HrpA 6.9e-21 ●●○○○ -1 -1.00287087926556
Escherichia coli M12  CO715_03025  ATI04801.1  253 aa sulfate transporter CysZ 3.7e-13 ●●○○○ -1 -1.00287087926556
Escherichia coli M12  CO715_15880  ATI07058.1  271 aa carboxymethylenebutenolidase 0.00017 ●●○○○ -1 -1.00245358723706
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1782  WP_014344081.1  E8X8D1  narK  61 aa hypothetical protein 4.9e-5 ●●○○○ -1 -1.00233551279571
Escherichia coli M12  CO715_23475  ATI08409.1  720 aa type I secretion system permease/ATPase 5.9e-22 ●●○○○ -1 -1.00203629520856
Acinetobacter baumannii ATCC 17978  A1S_1874  ABO12301.2  306 aa putative transcriptional regulator (LysR family) 5.1e-9 ●●○○○ -1 -1.00196649499235
Escherichia coli M12  CO715_11100  ATI06200.1  249 aa chitooligosaccharide deacetylase 7.9e-32 ●●○○○ -1 -1.00141035716582
Escherichia coli M12  CO715_03335  ATI04853.1  251 aa phospholipid-binding lipoprotein MlaA 1.7e-35 ●●○○○ -1 -1.00120171115157
Escherichia coli M12  CO715_04515  ATI05066.1  366 aa thiazolinyl imide reductase 1.3e-60 ●●○○○ -1 -1.00099306513732
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2209  NP_231840.1  2413 aa nonribosomal peptide synthetase VibF 3.2e-6 ●●○○○ -1 -1.00092030343131
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0460  WP_000019878.1  E8XKM7  cyoD  109 aa cytochrome o ubiquinol oxidase subunit IV 5.5e-6 ●●○○○ -1 -1.00067788460956
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1286  NP_230931.1  Q9KSH0  340 aa LacI family transcription regulator 1.1e-6 ●●○○○ -1 -1.00058423887655
Salmonella enterica Serovar Typhimurium SL1344  SL1344_3749  CBW19840.1  A0A0H3NHK0  95 aa hypothetical IIB component of PTS system 0.049 ●○○○○ -1 -0.999056706153447
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1633  NP_231270.1  Q9KRK7  245 aa hypothetical protein 0.0019 ●○○○○ -1 -0.999044060892688
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4248  AIK82793.1  190 aa bacterial regulatory, luxR family protein 1.0e-7 ●○○○○ -1 -0.998760026482244
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4033  AIK82580.1  449 aa sensor protein qseC <1e-323 ●○○○○ -1 -0.998650617643058
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1325  WP_001010662.1  E8XGC7  ydjN  463 aa L-cystine transporter 9.9e-6 ●○○○○ -1 -0.998648957302492
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3779  WP_000158675.1  E8XFC3  686 aa AsmA family protein 8.4e-5 ●○○○○ -1 -0.998524391357285
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0055  WP_000377406.1  E8XG74  228 aa response regulator 0.00048 ●○○○○ -1 -0.998269476897438
Escherichia coli M12  CO715_05320  ATI05200.1  654 aa chemotaxis protein CheA 1.9e-40 ●○○○○ -1 -0.998072020937836
Escherichia coli M12  CO715_03575  ATI04899.1  180 aa NUDIX hydrolase 0.0036 ●○○○○ -1 -0.998072020937836
Escherichia coli CFT073  c1688  AAN80155.1  A0A0H2V978  narI  225 aa Respiratory nitrate reductase 1 gamma chain 0.039 ●○○○○ -1 -0.997330890775445
Escherichia coli M12  CO715_20110  ATI07822.1  294 aa nucleoside-specific channel-forming protein Tsx 1.1e-13 ●○○○○ -1 -0.99723743688084
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0040  WP_001055835.1  E8XG59  417 aa hypothetical protein 0.026 ●○○○○ -1 -0.997093316296045
Escherichia coli M12  CO715_06385  ATI05379.1  337 aa two-component system response regulator RssB 0.0083 ●○○○○ -1 -0.997028790866592
Escherichia coli M12  CO715_19180  ATI07652.1  61 aa lipoprotein 3.0e-10 ●○○○○ -1 -0.996611498838094
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1873  NP_231507.1  Q9KQX4  423 aa hypothetical protein 4.7e-6 ●○○○○ -1 -0.996524376567916
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3875  AIK82425.1  211 aa mlaC <1e-323 ●○○○○ -1 -0.995565599647985
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3562  AIK82118.1  187 aa 3-methyladenine DNA glycosylase I <1e-323 ●○○○○ -0.99 -0.994515768097818
Acinetobacter baumannii ATCC 17978  A1S_2386  ABO12805.2  322 aa putative ferric acinetobactin binding protein 0.0006 ●○○○○ -0.99 -0.994168929397013
Escherichia coli M12  CO715_06810  ATI05450.1  109 aa hypothetical protein 1.5e-26 ●○○○○ -0.99 -0.994107746667107
Escherichia coli M12  CO715_23145  ATI08366.1  248 aa SAM-dependent methyltransferase 1.1e-24 ●○○○○ -0.99 -0.99369045463861
Escherichia coli M12  CO715_08545  ATI05758.1  178 aa DNA-binding transcriptional regulator 4.5e-9 ●○○○○ -0.99 -0.993273162610112
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2048  NP_231682.1  Q9KQF0  254 aa VacJ lipoprotein 0.00011 ●○○○○ -0.99 -0.992754016247223
Acinetobacter baumannii ATCC 17978  A1S_1644  ABO12071.2  457 aa hypothetical protein 0.00074 ●○○○○ -0.99 -0.992748898849344
Porphyromonas gingivalis ATCC 33277  PGN_0484  WP_012457546.1  B2RI08  384 aa galactokinase 1.2e-9 ●○○○○ -0.99 -0.991902827193453
Escherichia coli M12  CO715_11880  ATI06344.1  318 aa AraC family transcriptional regulator 1.1e-16 ●○○○○ -0.99 -0.990978056453375
Porphyromonas gingivalis ATCC 33277  PGN_1475  WP_012458300.1  B2RKU9  228 aa 5'-methylthioadenosine/adenosylhomocysteine nucleosidase 9.4e-15 ●○○○○ -0.99 -0.990642525976095
Escherichia coli M12  CO715_19670  ATI07741.1  247 aa hypothetical protein 1.9e-9 ●○○○○ -0.99 -0.990560764424877
Salmonella enterica Serovar Typhimurium SL1344  SL1344_0054  CBW16155.1  A0A0H3NH19  citA2  539 aa two-component sensor kinase 0.047 ●○○○○ -0.99 -0.989969046303325
Retrieved entries 4,101–4,200 out of 36,363 total in 8.3 ms (Link to these results)