Browse BacFITBase

Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

Download Table  
Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Acinetobacter baumannii ATCC 17978  A1S_1649  ABO12076.2  479 aa Putative RND family drug transporter 0.00027 ●○○○○ -0.94 -0.944761297359051
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3163  WP_000253650.1  E8X9I8  araE  472 aa sugar porter family MFS transporter 0.017 ●○○○○ -0.94 -0.944243523732312
Escherichia coli M12  CO715_08080  ATI05673.1  396 aa aspartate aminotransferase 9.0e-29 ●○○○○ -0.94 -0.944032703247381
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0198  NP_232598.1  Q9KMW8  383 aa site-specific DNA-methyltransferase 0.0036 ●○○○○ -0.94 -0.943961871765805
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1807  WP_000070978.1  E8X8F6  597 aa Ni/Fe-hydrogenase large subunit 0.00025 ●○○○○ -0.94 -0.943850569706786
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3314  AIK81872.1  327 aa rbsR transcriptional repressor <1e-323 ●○○○○ -0.94 -0.943373438349715
Porphyromonas gingivalis ATCC 33277  PGN_0126  WP_012457266.1  B2RH00  429 aa MFS transporter <1e-323 ●○○○○ -0.94 -0.943132623491783
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1301  WP_001294900.1  E8XGA3  selD  347 aa selenide, water dikinase SelD 1.9e-8 ●○○○○ -0.94 -0.94267748240992
Porphyromonas gingivalis ATCC 33277  PGN_0719  WP_012457726.1  B2RIP3  789 aa ABC transporter permease <1e-323 ●○○○○ -0.94 -0.942259213766835
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3296  AIK81857.1  349 aa ntrB 0.0059 ●○○○○ -0.94 -0.942097770193866
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1951  AIK80557.1  195 aa transcriptional repressor BetI 1.2e-6 ●○○○○ -0.94 -0.941839188820062
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2719  WP_000669690.1  E8XHJ2  133 aa hypothetical protein 0.021 ●○○○○ -0.94 -0.941760023630645
Acinetobacter baumannii ATCC 17978  A1S_0914  ABO11346.1  242 aa hypothetical protein 0.0043 ●○○○○ -0.94 -0.941746875585762
Escherichia coli M12  CO715_21720  ATI08115.1  369 aa protein mrp 5.3e-11 ●○○○○ -0.94 -0.941737597090643
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4709  WP_001094622.1  E8XCF1  trpS2  337 aa tryptophan--tRNA ligase 5.5e-5 ●○○○○ -0.94 -0.941388388513103
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2366  WP_001061919.1  E8XEB2  rcsB  216 aa transcriptional regulator RcsB 2.2e-5 ●○○○○ -0.94 -0.940887514656483
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0990  NP_233374.1  Q9KKW0  428 aa DEAD/DEAH box helicase 0.00038 ●○○○○ -0.94 -0.939684746826251
Escherichia coli M12  CO715_12550  ATI06462.1  233 aa pirin family protein 0.0073 ●○○○○ -0.94 -0.938190614848413
Escherichia coli M12  CO715_06170  ATI05340.1  102 aa superoxide dismutase 1.1e-32 ●○○○○ -0.94 -0.937773322819915
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3107  WP_000097015.1  E8X8P6  gudT  452 aa MFS transporter 0.0001 ●○○○○ -0.94 -0.936585601856773
Escherichia coli CFT073  c0862  AAN79335.1  P65382  moaA  356 aa Molybdenum cofactor biosynthesis protein A 0.042 ●○○○○ -0.94 -0.935137912171921
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3057  AIK81642.1  106 aa branched-chain amino acid transport family protein 0.0041 ●○○○○ -0.93 -0.934510037903876
Escherichia coli M12  CO715_14410  ATI06795.1  450 aa glutathione-disulfide reductase 4.3e-12 ●○○○○ -0.93 -0.934434986591933
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0983  NP_230629.1  P24003  toxS  173 aa regulatory protein ToxS 2.7e-6 ●○○○○ -0.93 -0.933583252767775
Acinetobacter baumannii ATCC 17978  A1S_2460  ABO12878.2  231 aa putative transcriptional regulator (tetR family) 4.6e-6 ●○○○○ -0.93 -0.933315170553972
Escherichia coli M12  CO715_15855  ATI07053.1  340 aa lysophospholipase 1.3e-37 ●○○○○ -0.93 -0.932974464492191
Escherichia coli M12  CO715_11205  ATI06219.1  225 aa protein YdjY 2.4e-20 ●○○○○ -0.93 -0.932765818477942
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1867  NP_231501.1  Q9KQY0  342 aa hypothetical protein 2.3e-6 ●○○○○ -0.93 -0.932726075301782
Acinetobacter baumannii ATCC 17978  A1S_1821  ABO12248.1  254 aa Short-chain dehydrogenase/reductase SDR 4.3e-6 ●○○○○ -0.93 -0.931822380518583
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4544  WP_001236755.1  E8XAM6  1108 aa miniconductance mechanosensitive channel MscM 0.031 ●○○○○ -0.93 -0.931804236413426
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_2275  AIK80880.1  221 aa HAD phosphoserine phosphatase-like hydrolase, IBfamily protein 2.0e-6 ●○○○○ -0.93 -0.931101635176441
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3139  AIK81711.1  39 aa hypothetical protein 7.3e-14 ●○○○○ -0.93 -0.931071153921515
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0802  NP_230451.1  Q9KTT6  132 aa hypothetical protein 6.3e-5 ●○○○○ -0.93 -0.930945232609503
Escherichia coli M12  CO715_11720  ATI06314.1  262 aa 4,5-DOPA dioxygenase extradiol 2.2e-32 ●○○○○ -0.93 -0.930888004349702
Escherichia coli M12  CO715_19185  ATI07653.1  879 aa YdbH family protein 4.4e-75 ●○○○○ -0.93 -0.92963612826421
Escherichia coli M12  CO715_08895  ATI05821.1  150 aa molybdopterin synthase catalytic subunit MoaE 2.7e-10 ●○○○○ -0.93 -0.92963612826421
Escherichia coli M12  CO715_22300  ATI08222.1  229 aa uracil-DNA glycosylase 0.00015 ●○○○○ -0.93 -0.929010190221463
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4505  WP_000773784.1  E8X9W0  466 aa DUF1996 domain-containing protein 0.025 ●○○○○ -0.93 -0.928845423125776
Escherichia coli M12  CO715_23510  ATI08416.1  152 aa NfeD family protein 0.01 ●○○○○ -0.93 -0.928592898192965
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3258  AIK81819.1  457 aa sensory histidine kinase in two-component regulatory system with CpxR 8.6e-10 ●○○○○ -0.93 -0.927785839947628
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4724  WP_001595639.1  E8XCG6  47 aa hypothetical protein 0.0012 ●○○○○ -0.93 -0.927556556688807
Escherichia coli M12  CO715_10500  ATI06090.1  530 aa PTS sugar transporter subunit IIBC 1.8e-5 ●○○○○ -0.93 -0.927549668121721
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3312  WP_000130262.1  E8XB87  metC  395 aa cystathionine beta-lyase 0.028 ●○○○○ -0.93 -0.927031103666375
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4213  AIK82758.1  190 aa hypothetical protein 5.0e-15 ●○○○○ -0.93 -0.926783136840346
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3553  AIK82109.1  218 aa hypothetical protein <1e-323 ●○○○○ -0.92 -0.922987540040914
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0738  NP_233125.2  Q9KLK5  386 aa hypothetical protein 7.0e-5 ●○○○○ -0.92 -0.921576155390879
Escherichia coli M12  CO715_11695  ATI06309.1  66 aa glycogen synthase 0.00014 ●○○○○ -0.92 -0.920664349651508
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0323  NP_232719.1  Q9KML4  98 aa hypothetical protein 0.00015 ●○○○○ -0.92 -0.920458901922754
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3734  AIK82289.1  72 aa hypothetical protein <1e-323 ●○○○○ -0.92 -0.920457861466697
Porphyromonas gingivalis ATCC 33277  PGN_0290  WP_012457398.1  B2RHG4  333 aa hypothetical protein <1e-323 ●○○○○ -0.92 -0.920436801047332
Escherichia coli M12  CO715_03605  ATI04905.1  216 aa sugar phosphatase 2.6e-10 ●○○○○ -0.92 -0.920038411608762
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1038  WP_077248257.1  E8XDK1  501 aa host specificity protein J 2.4e-5 ●○○○○ -0.92 -0.919205657612476
Escherichia coli M12  CO715_19420  ATI07696.1  81 aa DUF2543 domain-containing protein 3.9e-16 ●○○○○ -0.92 -0.918786535523269
Porphyromonas gingivalis ATCC 33277  PGN_0085  WP_012457229.1  B2RGV9  143 aa DUF1896 domain-containing protein <1e-323 ●○○○○ -0.92 -0.918625633262929
Escherichia coli M12  CO715_02060  ATI04622.1  165 aa chorismate--pyruvate lyase 0.036 ●○○○○ -0.92 -0.917951951466273
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1541  NP_231181.1  Q9KRU3  327 aa hypothetical protein 6.4e-6 ●○○○○ -0.92 -0.917698895264514
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1987  NP_231621.1  Q9KQL1  202 aa outer membrane lipoprotein Slp 2.3e-7 ●○○○○ -0.92 -0.91623611369078
Escherichia coli M12  CO715_21250  ATI08030.1  159 aa cytochrome c-type biogenesis protein CcmE 0.00068 ●○○○○ -0.92 -0.915656845309536
Porphyromonas gingivalis ATCC 33277  PGN_0079  WP_012457223.1  B2RGV3  345 aa DUF1016 domain-containing protein <1e-323 ●○○○○ -0.92 -0.915581768924981
Escherichia coli M12  CO715_05270  ATI05190.1  329 aa arabinose ABC transporter substrate-binding protein 3.7e-16 ●○○○○ -0.92 -0.915239553281038
Porphyromonas gingivalis ATCC 33277  PGN_1041  WP_012457978.1  B2RJL5  529 aa cytochrome ubiquinol oxidase subunit I 3.2e-11 ●○○○○ -0.91 -0.913859006934632
Escherichia coli M12  CO715_19140  ATI08865.1  430 aa hypothetical protein 1.7e-73 ●○○○○ -0.91 -0.913570385167047
Escherichia coli M12  CO715_15845  ATI07051.1  206 aa threonine export protein RhtC 0.014 ●○○○○ -0.91 -0.913570385167047
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4723  AIK83257.1  279 aa ethanolamine utilization protein EutJ 1.2e-11 ●○○○○ -0.91 -0.912491624034988
Salmonella enterica Serovar Typhimurium ST4 74  STM474_3088  WP_000080404.1  E8X8M7  cysH  244 aa phosphoadenosine phosphosulfate reductase 0.01 ●○○○○ -0.91 -0.912283873703622
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3735  AIK82290.1  319 aa alpha/beta hydrolase fold family protein <1e-323 ●○○○○ -0.91 -0.912104017155658
Salmonella enterica Serovar Typhimurium ST4 74  STM474_1288  WP_001518010.1  E8XFL3  yeaG  644 aa PrkA family serine protein kinase 0.0003 ●○○○○ -0.91 -0.912056626774241
Acinetobacter baumannii ATCC 17978  A1S_2024  ABO12451.1  122 aa Glutamate 5-kinase 0.0024 ●○○○○ -0.91 -0.912028322567135
Salmonella enterica Serovar Typhimurium ST4 74  STM474_0951  WP_000850250.1  E8XCS1  dmsA  814 aa dimethylsulfoxide reductase subunit A 0.0041 ●○○○○ -0.91 -0.911954178962377
Porphyromonas gingivalis ATCC 33277  PGN_1106  WP_005873416.1  B2RJT0  176 aa hypothetical protein <1e-323 ●○○○○ -0.91 -0.91135132039301
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A1027  NP_233411.1  Q9KKS3  278 aa maltose operon periplasmic protein 2.0e-7 ●○○○○ -0.91 -0.91107350587112
Escherichia coli M12  CO715_06090  ATI05324.1  483 aa altronate oxidoreductase 8.2e-54 ●○○○○ -0.91 -0.909188818867821
Vibrio cholerae O1 biovar El Tor str. N16961  VC_1765  NP_231400.1  Q9KR78  1022 aa type I restriction enzyme HsdR 1.4e-5 ●○○○○ -0.91 -0.90842997730658
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_1727  AIK80347.1  70 aa putative dTDP-4-dehydrorhamnose reductase 0.019 ●○○○○ -0.91 -0.907755497736225
Escherichia coli M12  CO715_07810  ATI05624.1  360 aa phosphoporin PhoE 1.7e-213 ●○○○○ -0.91 -0.907728296768079
Salmonella enterica Serovar Typhimurium ST4 74  STM474_4065  WP_001738602.1  E8XIK6  rbsR  81 aa hypothetical protein 0.042 ●○○○○ -0.91 -0.907154348245446
Escherichia coli M12  CO715_06645  ATI05421.1  656 aa TonB-dependent receptor 3.7e-48 ●○○○○ -0.91 -0.907102358725332
Escherichia coli M12  CO715_07580  ATI05588.1  803 aa formate dehydrogenase-N subunit alpha 2.7e-8 ●○○○○ -0.91 -0.907102358725332
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2355  NP_231985.1  Q9KPL2  257 aa hypothetical protein 4.1e-7 ●○○○○ -0.91 -0.906599874841175
Escherichia coli M12  CO715_19590  ATI07728.1  196 aa cob(I)yrinic acid a,c-diamide adenosyltransferase 1.4e-10 ●○○○○ -0.91 -0.906059128654088
Escherichia coli M12  CO715_10515  ATI06093.1  346 aa oxidoreductase 4.0e-15 ●○○○○ -0.91 -0.905850482639839
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4275  AIK82820.1  470 aa 6-phospho-beta-glucosidase gmuD <1e-323 ●○○○○ -0.91 -0.905015974041412
Acinetobacter baumannii ATCC 17978  A1S_3176  ABO13573.2  532 aa putative membrane protein 0.0025 ●○○○○ -0.9 -0.90498103407535
Escherichia coli M12  CO715_19430  ATI07698.1  547 aa ABC transporter substrate-binding protein 2.8e-16 ●○○○○ -0.9 -0.904181314525848
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4421  AIK82964.1  50 aa hokE 2.3e-7 ●○○○○ -0.9 -0.904019256961218
Salmonella enterica Serovar Typhimurium ST4 74  STM474_2726  WP_000211410.1  E8XHJ8  187 aa ORF6N domain-containing protein 0.022 ●○○○○ -0.9 -0.903817092143558
Escherichia coli M12  CO715_02730  ATI04747.1  190 aa glycine cleavage system transcriptional repressor 0.011 ●○○○○ -0.9 -0.90376402249735
Escherichia coli M12  CO715_21195  ATI08021.1  207 aa hypothetical protein 1.7e-20 ●○○○○ -0.9 -0.903555376483102
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2082  NP_231714.1  Q9KQB8  znuC  262 aa zinc ABC transporter ATP-binding protein 1.5e-8 ●○○○○ -0.9 -0.903243929048672
Escherichia coli M12  CO715_01855  ATI04585.1  127 aa heme lyase NrfEFG subunit NrfF 0.0033 ●○○○○ -0.9 -0.902929438440355
Vibrio cholerae O1 biovar El Tor str. N16961  VC_A0849  NP_233235.1  Q9KL97  3263 aa hypothetical protein 0.00018 ●○○○○ -0.9 -0.90275377516103
Acinetobacter baumannii ATCC 17978  A1S_1020  ABO11452.2  672 aa penicillin-binding protein 2 0.00028 ●○○○○ -0.9 -0.901952176076406
Acinetobacter baumannii ATCC 17978  A1S_2139  ABO12566.2  201 aa hypothetical protein 0.00034 ●○○○○ -0.9 -0.901499781098744
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_4088  AIK82634.1  342 aa periplasmic binding and sugar binding domain of LacI family protein 0.00022 ●○○○○ -0.9 -0.901448683076368
Escherichia coli M12  CO715_16505  ATI07175.1  95 aa ferredoxin-like protein FixX 3.1e-5 ●○○○○ -0.9 -0.900842978297866
Escherichia coli M12  CO715_18635  ATI07556.1  427 aa histidine kinase 1.5e-30 ●○○○○ -0.9 -0.900634332283618
Vibrio cholerae O1 biovar El Tor str. N16961  VC_0086  NP_229745.1  P57051  tatA  82 aa twin-arginine translocation protein TatA 2.3e-7 ●○○○○ -0.9 -0.900237444444853
Vibrio cholerae O1 biovar El Tor str. N16961  VC_2567  NP_232195.1  Q9KP12  190 aa hypothetical protein 2.3e-7 ●○○○○ -0.9 -0.900003805020071
Escherichia coli M12  CO715_19660  ATI07740.1  212 aa outer membrane protein OmpW 1.3e-99 ●○○○○ -0.9 -0.899799748226622
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1  VK055_3369  AIK81926.1  367 aa galactonate dehydratase 9.2e-14 ●○○○○ -0.9 -0.899250114078673
Retrieved entries 4,301–4,400 out of 36,363 total in 9.2 ms (Link to these results)