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Sorted by significance (p<0.05) and Fitness z-Scores (highest impact first):

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Pathogen Locus Protein UniProt Gene Length Product p-Value Fitness z-Score  Precise fitness z-Score
Escherichia coli M12  CO715_21720  ATI08115.1  369 aa protein mrp 5.3e-11 ●○○○○ -0.94 -0.941737597090643
Escherichia coli M12  CO715_12550  ATI06462.1  233 aa pirin family protein 0.0073 ●○○○○ -0.94 -0.938190614848413
Escherichia coli M12  CO715_06170  ATI05340.1  102 aa superoxide dismutase 1.1e-32 ●○○○○ -0.94 -0.937773322819915
Escherichia coli M12  CO715_14410  ATI06795.1  450 aa glutathione-disulfide reductase 4.3e-12 ●○○○○ -0.93 -0.934434986591933
Escherichia coli M12  CO715_15855  ATI07053.1  340 aa lysophospholipase 1.3e-37 ●○○○○ -0.93 -0.932974464492191
Escherichia coli M12  CO715_11205  ATI06219.1  225 aa protein YdjY 2.4e-20 ●○○○○ -0.93 -0.932765818477942
Escherichia coli M12  CO715_11720  ATI06314.1  262 aa 4,5-DOPA dioxygenase extradiol 2.2e-32 ●○○○○ -0.93 -0.930888004349702
Escherichia coli M12  CO715_19185  ATI07653.1  879 aa YdbH family protein 4.4e-75 ●○○○○ -0.93 -0.92963612826421
Escherichia coli M12  CO715_08895  ATI05821.1  150 aa molybdopterin synthase catalytic subunit MoaE 2.7e-10 ●○○○○ -0.93 -0.92963612826421
Escherichia coli M12  CO715_22300  ATI08222.1  229 aa uracil-DNA glycosylase 0.00015 ●○○○○ -0.93 -0.929010190221463
Escherichia coli M12  CO715_23510  ATI08416.1  152 aa NfeD family protein 0.01 ●○○○○ -0.93 -0.928592898192965
Escherichia coli M12  CO715_10500  ATI06090.1  530 aa PTS sugar transporter subunit IIBC 1.8e-5 ●○○○○ -0.93 -0.927549668121721
Escherichia coli M12  CO715_11695  ATI06309.1  66 aa glycogen synthase 0.00014 ●○○○○ -0.92 -0.920664349651508
Escherichia coli M12  CO715_03605  ATI04905.1  216 aa sugar phosphatase 2.6e-10 ●○○○○ -0.92 -0.920038411608762
Escherichia coli M12  CO715_19420  ATI07696.1  81 aa DUF2543 domain-containing protein 3.9e-16 ●○○○○ -0.92 -0.918786535523269
Escherichia coli M12  CO715_02060  ATI04622.1  165 aa chorismate--pyruvate lyase 0.036 ●○○○○ -0.92 -0.917951951466273
Escherichia coli M12  CO715_21250  ATI08030.1  159 aa cytochrome c-type biogenesis protein CcmE 0.00068 ●○○○○ -0.92 -0.915656845309536
Escherichia coli M12  CO715_05270  ATI05190.1  329 aa arabinose ABC transporter substrate-binding protein 3.7e-16 ●○○○○ -0.92 -0.915239553281038
Escherichia coli M12  CO715_19140  ATI08865.1  430 aa hypothetical protein 1.7e-73 ●○○○○ -0.91 -0.913570385167047
Escherichia coli M12  CO715_15845  ATI07051.1  206 aa threonine export protein RhtC 0.014 ●○○○○ -0.91 -0.913570385167047
Escherichia coli M12  CO715_06090  ATI05324.1  483 aa altronate oxidoreductase 8.2e-54 ●○○○○ -0.91 -0.909188818867821
Escherichia coli M12  CO715_07810  ATI05624.1  360 aa phosphoporin PhoE 1.7e-213 ●○○○○ -0.91 -0.907728296768079
Escherichia coli M12  CO715_06645  ATI05421.1  656 aa TonB-dependent receptor 3.7e-48 ●○○○○ -0.91 -0.907102358725332
Escherichia coli M12  CO715_07580  ATI05588.1  803 aa formate dehydrogenase-N subunit alpha 2.7e-8 ●○○○○ -0.91 -0.907102358725332
Escherichia coli M12  CO715_19590  ATI07728.1  196 aa cob(I)yrinic acid a,c-diamide adenosyltransferase 1.4e-10 ●○○○○ -0.91 -0.906059128654088
Escherichia coli M12  CO715_10515  ATI06093.1  346 aa oxidoreductase 4.0e-15 ●○○○○ -0.91 -0.905850482639839
Escherichia coli M12  CO715_19430  ATI07698.1  547 aa ABC transporter substrate-binding protein 2.8e-16 ●○○○○ -0.9 -0.904181314525848
Escherichia coli M12  CO715_02730  ATI04747.1  190 aa glycine cleavage system transcriptional repressor 0.011 ●○○○○ -0.9 -0.90376402249735
Escherichia coli M12  CO715_21195  ATI08021.1  207 aa hypothetical protein 1.7e-20 ●○○○○ -0.9 -0.903555376483102
Escherichia coli M12  CO715_01855  ATI04585.1  127 aa heme lyase NrfEFG subunit NrfF 0.0033 ●○○○○ -0.9 -0.902929438440355
Escherichia coli M12  CO715_16505  ATI07175.1  95 aa ferredoxin-like protein FixX 3.1e-5 ●○○○○ -0.9 -0.900842978297866
Escherichia coli M12  CO715_18635  ATI07556.1  427 aa histidine kinase 1.5e-30 ●○○○○ -0.9 -0.900634332283618
Escherichia coli M12  CO715_19660  ATI07740.1  212 aa outer membrane protein OmpW 1.3e-99 ●○○○○ -0.9 -0.899799748226622
Escherichia coli M12  CO715_18795  ATI07583.1  356 aa 3-deoxy-7-phosphoheptulonate synthase 7.7e-16 ●○○○○ -0.9 -0.896670058012889
Escherichia coli M12  CO715_14330  ATI06779.1  660 aa TonB-dependent receptor 1.3e-35 ●○○○○ -0.9 -0.89646141199864
Escherichia coli M12  CO715_21120  ATI08008.1  542 aa anaerobic glycerol-3-phosphate dehydrogenase subunit A 2.8e-27 ●○○○○ -0.9 -0.89646141199864
Escherichia coli M12  CO715_06305  ATI05364.1  417 aa voltage-gated potassium channel 2.7e-35 ●○○○○ -0.9 -0.896252765984392
Escherichia coli M12  CO715_19380  ATI07689.1  325 aa phage shock protein operon transcriptional activator 0.00014 ●○○○○ -0.9 -0.896044119970143
Escherichia coli M12  CO715_04580  ATI05076.1  211 aa sulfoxide reductase heme-binding subunit YedZ 3.2e-34 ●○○○○ -0.9 -0.895418181927396
Escherichia coli M12  CO715_21395  ATI08056.1  393 aa sugar efflux transporter SetB 3.5e-12 ●○○○○ -0.9 -0.895209535913147
Escherichia coli M12  CO715_21610  ATI08094.1  310 aa D-alanyl-D-alanine endopeptidase 7.1e-61 ●○○○○ -0.89 -0.894583597870401
Escherichia coli M12  CO715_05960  ATI05302.1  427 aa MFS transporter 6.0e-33 ●○○○○ -0.89 -0.894374951856152
Escherichia coli M12  CO715_01130  ATI04458.1  330 aa asparagine synthetase A 3.7e-9 ●○○○○ -0.89 -0.893331721784908
Escherichia coli M12  CO715_22625  ATI08275.1  450 aa cell envelope integrity protein CreD 6.3e-10 ●○○○○ -0.89 -0.89291442975641
Escherichia coli M12  CO715_11335  ATI06244.1  358 aa alcohol dehydrogenase 1.8e-23 ●○○○○ -0.89 -0.891871199685166
Escherichia coli M12  CO715_09980  ATI06009.1  50 aa protein HokE 5.2e-6 ●○○○○ -0.89 -0.891245261642419
Escherichia coli M12  CO715_22225  ATI08209.1  376 aa dTDP-4-amino-4,6-dideoxygalactose transaminase 1.5e-29 ●○○○○ -0.89 -0.890827969613921
Escherichia coli M12  CO715_03515  ATI04887.1  189 aa 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 2.8e-100 ●○○○○ -0.89 -0.889784739542677
Escherichia coli M12  CO715_18800  ATI07584.1  373 aa bifunctional chorismate mutase/prephenate dehydrogenase 0.0061 ●○○○○ -0.89 -0.889784739542677
Escherichia coli M12  CO715_08770  ATI05798.1  240 aa glutamine ABC transporter ATP-binding protein 6.3e-24 ●○○○○ -0.89 -0.888115571428686
Escherichia coli M12  CO715_20860  ATI07959.1  134 aa flagellar basal body rod protein FlgC 0.0033 ●○○○○ -0.89 -0.887072341357442
Escherichia coli M12  CO715_08530  ATI05755.1  85 aa GrxA family glutaredoxin 0.0014 ●○○○○ -0.89 -0.886446403314695
Escherichia coli M12  CO715_21340  ATI08045.1  529 aa microcin C ABC transporter ATP-binding protein YejF 4.9e-8 ●○○○○ -0.88 -0.884359943172206
Escherichia coli M12  CO715_09360  ATI05900.1  247 aa Nif3-like dinuclear metal center hexameric protein 2.1e-137 ●○○○○ -0.88 -0.883316713100962
Escherichia coli M12  CO715_20785  ATI07944.1  372 aa N-methyl-L-tryptophan oxidase 1.3e-59 ●○○○○ -0.88 -0.883108067086713
Escherichia coli M12  CO715_11490  ATI06273.1  561 aa long-chain-fatty-acid--CoA ligase 3.0e-9 ●○○○○ -0.88 -0.882899421072465
Escherichia coli M12  CO715_10435  ATI06078.1  239 aa DNA-binding response regulator 2.0e-15 ●○○○○ -0.88 -0.882690775058216
Escherichia coli M12  CO715_11950  ATI06357.1  328 aa hydrogenase-2 operon protein HybA 2.2e-39 ●○○○○ -0.88 -0.882482129043967
Escherichia coli M12  CO715_14235  ATI08816.1  122 aa glutamate decarboxylase 2.6e-5 ●○○○○ -0.88 -0.881438898972722
Escherichia coli M12  CO715_01505  ATI04523.1  117 aa hypothetical protein 0.02 ●○○○○ -0.88 -0.876640040644999
Escherichia coli M12  CO715_11770  ATI06323.1  275 aa phosphodiesterase 0.00013 ●○○○○ -0.87 -0.873718996445515
Escherichia coli M12  CO715_11210  ATI06220.1  235 aa TVP38/TMEM64 family protein 0.00038 ●○○○○ -0.87 -0.873510350431266
Escherichia coli M12  CO715_13690  ATI08811.1  237 aa oxidoreductase 1.6e-11 ●○○○○ -0.87 -0.87267576637427
Escherichia coli M12  CO715_21100  ATI08004.1  65 aa hypothetical protein 0.00012 ●○○○○ -0.87 -0.872258474345773
Escherichia coli M12  CO715_11095  ATI06199.1  753 aa catalase HPII 3.2e-61 ●○○○○ -0.87 -0.872049828331524
Escherichia coli M12  CO715_11380  ATI06253.1  491 aa GGDEF domain-containing protein 4.8e-218 ●○○○○ -0.87 -0.869754722174786
Escherichia coli M12  CO715_04440  ATI05054.1  316 aa transcriptional regulator Cbl 0.00062 ●○○○○ -0.87 -0.867042323989551
Escherichia coli M12  CO715_04990  ATI05145.1  388 aa UDP-glucose 6-dehydrogenase 2.5e-23 ●○○○○ -0.87 -0.866833677975302
Escherichia coli M12  CO715_07620  ATI05596.1  71 aa protein bdm 3.0e-27 ●○○○○ -0.87 -0.865790447904058
Escherichia coli M12  CO715_17645  ATI07382.1  163 aa hypothetical protein 0.00081 ●○○○○ -0.86 -0.864955863847062
Escherichia coli M12  CO715_08250  ATI05705.1  814 aa dimethylsulfoxide reductase subunit A 3.8e-31 ●○○○○ -0.86 -0.863912633775818
Escherichia coli M12  CO715_00825  ATI04405.1  110 aa YceK/YidQ family lipoprotein 2.3e-27 ●○○○○ -0.86 -0.862869403704574
Escherichia coli M12  CO715_21075  ATI08001.1  1148 aa transcription-repair coupling factor 4.0e-16 ●○○○○ -0.86 -0.862660757690325
Escherichia coli M12  CO715_04325  ATI05040.1  196 aa hypothetical protein 4.0e-5 ●○○○○ -0.86 -0.861617527619081
Escherichia coli M12  CO715_21375  ATI08052.1  328 aa GTP-binding protein 0.041 ●○○○○ -0.86 -0.860782943562085
Escherichia coli M12  CO715_10115  ATI06028.1  177 aa lysozyme 5.9e-18 ●○○○○ -0.86 -0.85994835950509
Escherichia coli M12  CO715_14670  ATI06845.1  221 aa VUT family protein 2.7e-31 ●○○○○ -0.86 -0.859322421462343
Escherichia coli M12  CO715_02895  ATI04776.1  295 aa ethanolamine ammonia-lyase light chain 9.1e-13 ●○○○○ -0.86 -0.856610023277108
Escherichia coli M12  CO715_08930  ATI05828.1  225 aa ATP-dependent dethiobiotin synthetase BioD 7.3e-8 ●○○○○ -0.85 -0.854940855163117
Escherichia coli M12  CO715_10195  ATI06038.1  341 aa hypothetical protein 4.7e-7 ●○○○○ -0.85 -0.852019810963633
Escherichia coli M12  CO715_09350  ATI05898.1  310 aa hypothetical protein 0.023 ●○○○○ -0.85 -0.848681474735651
Escherichia coli M12  CO715_08835  ATI05810.1  454 aa ATP-dependent RNA helicase RhlE 1.4e-25 ●○○○○ -0.85 -0.848055536692905
Escherichia coli M12  CO715_21925  ATI08154.1  450 aa molecular chaperone 3.2e-29 ●○○○○ -0.85 -0.847220952635909
Escherichia coli M12  CO715_10375  ATI06067.1  273 aa serine protease 2.6e-28 ●○○○○ -0.84 -0.842839386336683
Escherichia coli M12  CO715_09425  ATI05912.1  894 aa two-component system sensor histidine kinase KdbD 4.6e-14 ●○○○○ -0.84 -0.842004802279688
Escherichia coli M12  CO715_17925  ATI07430.1  41 aa hypothetical protein 1.0e-5 ●○○○○ -0.84 -0.840126988151448
Escherichia coli M12  CO715_16750  ATI07221.1  319 aa class 1b ribonucleoside-diphosphate reductase subunit beta 6.7e-42 ●○○○○ -0.84 -0.838666466051706
Escherichia coli M12  CO715_11815  ATI06331.1  130 aa TIGR00156 family protein 8.7e-11 ●○○○○ -0.84 -0.836997297937715
Escherichia coli M12  CO715_03040  ATI04804.1  72 aa hypothetical protein 7.4e-5 ●○○○○ -0.84 -0.836580005909217
Escherichia coli M12  CO715_01955  ATI04603.1  93 aa hypothetical protein 0.016 ●○○○○ -0.84 -0.836580005909217
Escherichia coli M12  CO715_01650  ATI04549.1  451 aa alpha-glucosidase/alpha-galactosidase 2.3e-6 ●○○○○ -0.84 -0.835954067866471
Escherichia coli M12  CO715_07605  ATI05593.1  336 aa alcohol dehydrogenase AdhP 6.2e-60 ●○○○○ -0.83 -0.834702191780978
Escherichia coli M12  CO715_08115  ATI05679.1  261 aa tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM 0.012 ●○○○○ -0.83 -0.833867607723982
Escherichia coli M12  CO715_06100  ATI05326.1  304 aa hypothetical protein 1.0e-27 ●○○○○ -0.83 -0.831989793595742
Escherichia coli M12  CO715_16780  ATI07227.1  245 aa branched-chain amino acid ABC transporter permease 1.8e-44 ●○○○○ -0.83 -0.830737917510249
Escherichia coli M12  CO715_04785  ATI05110.1  77 aa SirA-like protein 0.0043 ●○○○○ -0.83 -0.829277395410507
Escherichia coli M12  CO715_14440  ATI06801.1  144 aa universal stress protein A 3.2e-12 ●○○○○ -0.83 -0.828442811353512
Escherichia coli M12  CO715_09370  ATI05902.1  472 aa deoxyribodipyrimidine photo-lyase 2.8e-11 ●○○○○ -0.83 -0.825939059182525
Escherichia coli M12  CO715_09715  ATI05960.1  403 aa D-alanyl-D-alanine carboxypeptidase 4.4e-18 ●○○○○ -0.83 -0.825730413168277
Escherichia coli M12  CO715_07125  ATI05508.1  79 aa DUF4222 domain-containing protein 7.1e-8 ●○○○○ -0.82 -0.824478537082783
Retrieved entries 1,201–1,300 out of 3,550 total in 46.2 ms (Link to these results)